化学感覚分野で、数多くの研究成果を挙げています。
東原グループでは、発足1999年以降嗅覚研究を進めています。
その研究成果を論文や総説など様々なかたちで発表していますので紹介します。
生体膜形態形成(酵母)G発表論文 舘川准教授 ~2023.3在籍
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著 者 Yang Y, Liu G, Li F, Carey LB, Sun C, Ling K, Tachikawa H, Fujita M, Gao XD, Nakanishi H. タイトル "Receptor for advanced glycation end-products (RAGE) mediates phagocytosis in nonprofessional phagocytes" 掲載誌名 Communications Biology 5(1) 824 (2022) -
著 者 Liu G, Yang Y, Tachikawa H, Gao XD, Nakanishi H. タイトル "Application of yeast spores as β-glucan particles" 掲載誌名 Particuology 71: 34-40 (2022) -
著 者 Nakamura TS, Suda Y, Muneshige K, Fujieda Y, Okumura Y, Inoue I, Tanaka T, Takahashi T, Nakanishi H, Gao XD, Okada Y, Neiman AM, and Tachikawa H. タイトル "Suppression of Vps13 adaptor protein mutants reveals a central role for PI4P in regulating prospore membrane extension" 掲載誌名 PLOS Genetics 17(8): e1009727 (2021) -
著 者 Li F, Yang G, Tachikawa H, Shao K, Gao XD, Nakanishi H. タイトル "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT" 掲載誌名 The Journal of General and Applied Microbiology 67(1):33-41 (2021) -
著 者 Suda Y, Tachikawa H, Inoue I, Kurita T, Saito C, Kurokawa K, Nakano A, Irie K. タイトル "Activation of Rab GTPase Sec4 by its GEF Sec2 is required for prospore membrane formation during sporulation in yeast Saccharomyces cerevisiae" 掲載誌名 FEMS Yeast Research 18(1) (2018) -
著 者 Pan HP, Wang N, Tachikawa H, Gao XD, Nakanishi H. タイトル "Osw2 is required for proper assembly of glucan and/or mannan layers of the yeast spore wall" 掲載誌名 J. Biochem 163(4): 293-304 (2018) -
著 者 Nakamura TS, Numajiri Y, Okumura Y, Hidaka J, Tanaka T, Inoue I, Suda Y, Takahashi T, Nakanishi H, Gao XD, Neiman AM, Tachikawa H. タイトル "Dynamic localization of a yeast development-specific PP1 complex during prospore membrane formation is dependent on multiple localization signals and complex formation." 掲載誌名 Mol. Biol. Cell 28: 3881-3895 (2017) -
著 者 Pan HP, Wang N, Tachikawa H, Nakanishi H, Gao XD. タイトル "β-1,6-glucan synthesis-associated genes are required for proper spore wall formation in Saccharomyces cerevisiae." 掲載誌名 Yeast 34(11): 431-446 (2017) -
著 者 Okumura Y, Nakamura TS, Tanaka T, Inoue I, Suda Y, Takahashi T, Nakanishi H, Nakamura S, Gao XD, Tachikawa H タイトル "The Dysferlin domain-only protein, Spo73, is required for prospore membrane extension in Saccharomyces cerevisiae" 掲載誌名 mSphere 1(1): e00038-15 (2016) -
著 者 Mohamed LA, Tachikawa H, Gao XD, Nakanishi H タイトル "Yeast cell-based analysis of human lactate dehydrogenase isoforms" 掲載誌名 J. Biochem. 158(6):467-76 (2015) -
著 者 Zhang H, Tachikawa H, Gao XD, Nakanishi H タイトル "Applied uses of yeast spores as chitosan beads" 掲載誌名 Applied and Environmental Microbiology 80(16): 5098-5105 (2014) -
著 者 Shi L, Li Z, Tachikawa H, Gao XD, Nakanishi H タイトル "Microencapsulation of enzymes using yeast spores" 掲載誌名 Applied and Environmental Microbiology 80(15): 4502-4510 (2014) -
著 者 Park JS, Okumura Y, Tachikawa H, Neiman AM タイトル "SPO71 encodes a developmental stage-specific partner for Vps13 in Saccharomyces cerevisiae." 掲載誌名 Eukaryot Cell 12(11): 1530-1537 (2013) -
著 者 Lu J, Takahashi T, Ohoka A, Nakajima K, Hasjimoto R, Miura N, Tachikawa H, Gao XD タイトル "Alg14 organizes the formation of multi-glycosyltransferase complex involved in initiation of lipid-linked oligosaccharide biogenesis." 掲載誌名 Glycobiology 22(4): 504-516 (2012) -
著 者 Onishi M, Koga T, Hirata A, Nakamura T, Asakawa H, Shimoda C, Bähler J, Wu JQ, Takegawa K. Tachikawa H, Pringle JR, Fukui Y タイトル Role of septins in the orientation of forespore-membrane extension during sporulation in fission yeast. 掲載誌名 Mol. Cell. Biol. 30(8): 2057-2074 (2010) -
著 者 Ishihara M, Suda Y, Inoue I, Tanaka T, Takahashi T, Gao XD, Fukui Y, Ihara S, Neiman AM, Tachikawa H タイトル A protein phosphatase type 1-interacting protein Ysw1 is involved in proper septin organization and prospore membrane formation during sporulation. 掲載誌名 Eukaryotic Cell 8: 1027-1037 (2009) -
著 者 Diamond A, Park JS, Inoue I, Tachikawa H, Neiman AM タイトル The anaphase promoting complex targeting subunit Ama1 links meiotic exit to cytokinesis during sporulation in Saccharomyces cerevisiae. 掲載誌名 Mol. Biol. Cell 20: 134-145 (2009) -
著 者 Pablo-Hernando EM, Arnaiz-Pita Y, Tachikawa H, Rey F, Neiman AM, Vazquez CR タイトル Septins localize to microtubules during nutritional limitation in Saccharomyces cerevisiae. 掲載誌名 BMC Cell Biology 9: 55 (2008) -
著 者 Onishi M, Iida M, Koga T, Yamada S, Hirata A, Iwaki T, Takegawa K, Fukui Y, Tachikawa H タイトル Fission yeast Sst4p, a conserved Vps27/Hrs homolog, functions downstream of PtdIns 3-kinase Pik3p to mediate proper spore formation. 掲載誌名 Eukaryotic Cell 6: 2343-2353 (2007) -
著 者 Gao XD, Tachikawa H, Sato T, Jigami Y, Dean N タイトル Alg14 recruits Alg13 to the cytoplasmic face of endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation. 掲載誌名 J. Biol. Chem. 280: 36254-36262 (2005) -
著 者 Tachikawa H, Bloecher A, Tatchell K, Neiman AM タイトル Gip1p-Glc7p phosphatase complex regulates septin organization and spore wall formation. 掲載誌名 J. Cell Biol. 155: 797-808 (2001)
その他共同研究の論文
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著 者 Izumikawa K, Ishikawa H, Yoshikawa H, Fujiyama S, Watanabe A, Aburatani H, Tachikawa H, Hayano T, Isobe T, Simpson R, Li L, Min J, Takahashi N. タイトル "LYAR potentiates rRNA synthesis by recruting BRD2/4 and MYST-type acetyltransferase KAT7 to rDNA" 掲載誌名 Nucleic Acids Research 47(19):10357-10372 (2019) -
著 者 Takahashi T, Nedachi T, Etoh T, Tachikawa H, Gao XD タイトル "Identification and characterization of transcriptional control region of human β1, 4-mannosyltransferase gene" 掲載誌名 Cytotechnology 69(3):417-434 (2017) -
著 者 Miura Y, Fujita H, Sakai F, Tachikawa H, Yagasaki K, Fujimoto D タイトル "Natural IgG antibody with anti-b-galactosyl specificity suppressed hepatoma cell invasion in culture." 掲載誌名 Cytotechnology 65(6): 909–913 (2013) -
著 者 Yoshikawa H, Komatsu W, Hayano T, Miura Y, Homma K, Izumikawa K, Ishikawa H, Miyazawa N, Tachikawa H, Yamauchi Y, Isobe T, Takahashi N タイトル Splicing factor 2-associated protein p32 participates in Ribosome biogenesis by regulating the binding of Nop52 and fibrillarin to pre-ribosome particles. 掲載誌名 Mol. Cell Proteomics. 10(8): M110.006148 (2011) -
著 者 Izumikawa K, Yanagida M, Hayano T, Tachikawa H, Komatsu W, Shimamoto A, Futami K, Furuichi Y, Shinkawa T, Yamauchi Y, Isobe T, Takahashi N タイトル Association of human DNA helicase RecQ5β with RNA polymerase II and its possible role in transcription. 掲載誌名 Biochemical J. 413: 505-516 (2008) -
著 者 Hamaguchi N, Ihara S, Ohdaira T, Nagano H, Iwamatsu A, Tachikawa H, Fukui Y タイトル Pleckstrin-2 selectively interacts with Phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading. 掲載誌名 Biochem. Biophys. Res. Commun. 361:270-275 (2007) -
著 者 Ishikawa H, Tachikawa H, Miura Y, Takahashi N タイトル TRIM11 binds to and destabilizes a key component of activator -mediated cofactor complex (ARC105) through the ubiquitin-proteasome system. 掲載誌名 FEBS Letters 580: 4784-4792 (2006)