sPLA₂に関する研究業績（2007年以前）

Naoko Konno, Ayako Nakamura, Yutaka Ikeno, So-hyun Cheon, Katsuhiko Kitamoto, and Manabu Arioka.
Novel neurotrophic effects of sphingosylphosphorylcholine in cerebellar granule neurons and in PC12 cells., Biochem. Biophys. Res. Commun. (2007)

Scott, G. A., Arioka, M., Jacobs, S. E.
Lysophosphatidylcholine mediates melanocyte dendricity through PKCzeta activation., J. Invest. Dermatol. 127(3), 668-675 (2006)

Ikeno, Y., Konno, N., Cheon, S.-h., Bolchi, A., Ottonello, S., Kitamoto, K., and Arioka, M.
Secretory phospholipases A₂ induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor., J. Biol. Chem. 280(30), 28044-28052 (2005)

Arioka, M., Ikeno, Y., Cheon, S.-h., Nakashima, S., and Kitamoto, K.
A novel neurotrophic role of secretory phospholipases A₂ for cerebellar granule neurons., FEBS Lett. 579(12), 2693-2701 (2005)

Masuda, S., Murakami, M., Takanezawa, Y., Aoki, J., Arai, H., Ishikawa, Y., Ishii, T., Arioka, M., and Kudo, I.
Neuronal expression and neuritogenic action of group X secreted phospholipase A₂., J. Biol. Chem. 280(24), 23203-23214 (2005)

有岡　学
分泌型ホスホリパーゼA2の神経栄養因子としての新規な作用、バイオサイエンスとインダストリー 63(5), 297-302 (2005)

Nakashima, S., Kitamoto, K., and Arioka, M.
The catalytic activity, but not receptor binding, of sPLA₂s plays a critical role for neurite outgrowth induction in PC12 cells., Brain Res. 1015(1-2), 207-211 (2004)

Arioka, M., Nakashima, S., Shibasaki, Y., and Kitamoto, K.
Dibasic amino acid residues at the carboxy-terminal end of kinase homology domain participate in the plasma membrane localization and function of phosphatidylinositol 5-kinase g., Biochem. Biophys. Res. Commun. 319(2), 456-463 (2004)

Nakashima, S., Ikeno, Y., Yokoyama, T., Kuwana, M., Bolchi, A., Ottonello, S., Kitamoto, K., and Arioka, M.
Secretory phospholipases A₂ induce neurite outgrowth in PC12 cells., Biochem. J. 376(3), 655-666 (2003)

Nakashima, S., Wakatsuki, S., Yokoyama, T., Arioka, M., and Kitamoto, K.
Identification and characterization of Scp15, a novel protein from Streptomyces coelicolor A3(2) with neurite-inducing activity in PC12 cells., Biosci. Biotech. Biochem. 67(1), 77-82 (2003)

Nakashima, S., Arioka, M., and Kitamoto, K.
Functional expression in Aspergillus oryzae of p15, a protein with potent neurite-inducing activity in PC12 cells., Biosci. Biotech. Biochem. 66(3), 674-678 (2002)

Wakatsuki, S., Yokoyama, T., Nakashima, S., Nishimura, A., Arioka, M., and Kitamoto, K.
Molecular cloning, functional expression and characterization of p15, a novel fungal protein with potent neurite-inducing activity in PC12 cells., Biochim. Biophys. Acta 1522(2), 74-81 (2001)

Wenk, M. R., Pellegrini, L., Klenchin, V. A., Di Paolo, G., Chang, S., Daniell, L., Arioka, M., Martin, T. F., and De Camilli, P.
PIP kinase Ig is the major PI(4,5)P₂ synthesizing enzyme at the synapse., Neuron 32(1), 79-88 (2001)

Wakatsuki, S., Arioka, M., Dohmae, N., Takio, K., Yamasaki, M., and Kitamoto, K.
Characterization of a novel fungal protein p15 which induces neuronal differentiation of PC12 cells., J. Biochem. 126(6), 1151-1160 (1999)

Sato, T., Hanada, T., Arioka, M., Morita, T., Koshino, H., J., Uramoto, M., Yamasaki, M., and Kitamoto, K.
S19159, a modulator of neurite outgrowth produced by the ascomycete Preussia aemulans. II. Structure elucidation., J. Antibiot. 51(11), 1047-1050 (1998)

Sato, T., Hanada, T., Arioka, M., Ando, K., Sugiyama, J., Uramoto, M., Yamasaki, M., and Kitamoto, K.
S19159, a modulator of neurite outgrowth produced by the ascomycete Preussia aemulans. I. Producing strain, fermentation, isolation and biological activity., J. Antibiot. 51(10), 897-901 (1998)

Ho, S.-C., Wakatsuki, S., Arioka, M., Yamasaki, and Kitamoto, K.
Identification and characterization of porcine NP-190, a novel protein that is specifically expressed in the axonal membrane during the embryonic period., J. Biochem. 123(2), 332-338 (1998)

Wakatsuki, S., Ho, S.-C., Arioka, M., Yamasaki, M., and Kitamoto, K.
Isolation and characterization of a 230 kDa protein (p230) specifically expressed in fetal brains: its involvement in neurite outgrowth from rat cerebral cortex neurons grown on monolayer of astrocytes., J. Biochem. 122(6), 1146-1152 (1997)

Hanada, T., Sato, T., Arioka, M., Uramoto, M., and Yamasaki, M.
Purification and characterization of a 15 kDa protein (p15) produced by Helicosporium which exhibits distinct effects on neurite outgrowth from cortical neurons and PC12 cells., Biochem. Biophys. Res. Comm. 228(1), 209-215 (1996)