研究報文
2017年
  • Heterologous expression in Pichia pastoris and characterization of a beta-glucosidase from the xylophagous cockroach Panesthia angustipennis spadica displaying high specific activity for cellobiose
  • Li, Y., Arakawa, G., Tokuda, G., Watanabe, H., and Arioka, M.
  • Enzyme Microb. Technol., 97, 104-113 (2017)
  • AoAtg26, a putative sterol glucosyltransferase, is required for autophagic degradation of peroxisomes, mitochondria, and nuclei in the filamentous fungus Aspergillus oryzae
  • T. Kikuma, T. Tadokoro, J. Maruyama, K. Kitamoto
  • Biosci. Biotechnol Biochem., 81, 384-395 (2017)
2016年
  • Carbon and nitrogen depletion-induced nucleophagy and selective autophagic sequestration of a whole nucleus in multinucleate cells of the filamentous fungus Aspergillus oryzae
  • T. Kikuma, T. Mitani, T. Kohara, J. Maruyama, K. Kitamoto
  • J. Gen. Appl. Microbiol., in press (2016)
  • Subcellular localization of acyl-CoA binding protein in Aspergillus oryzae is regulated by autophagy machinery
  • K. Kawaguchi, T. Kikuma, Y. Higuchi, K. Takegawa, K. Kitamoto
  • Biochem. Biophys. Res. Commun. 480, 8-12 (2016)
  • Yor022c protein is a phospholipase A1 that localizes to the mitochondrial matrix
  • Urafuji, K. and Arioka, M.
  • Biochem. Biophys. Res. Commun. 480, 302-308 (2016)
  • Mitochondria-localized phospholipase A2, AoPlaA, in Aspergillus oryzae displays phosphatidylethanolamine-specific activity and is involved in the maintenance of mitochondrial phospholipid composition
  • Kotani, S., Izawa, S., Komai, N., Takayanagi, A., and Arioka, M.
  • Fungal Genet. Biol. 96, 1-11 (2016)
  • Functional expression and characterization of a glucuronoyl esterase from the fungus Neurospora crassa: identification of novel consensus sequences containing the catalytic triad
  • Huynh, H.H. and Arioka, M.
  • J. Gen. Appl. Microbiol., in press (2016)
  • Comparative genomic analysis identified a mutation related to enhanced heterologous protein production in the filamentous fungus Aspergillus oryzae
  • F. J. Jin, T. Katayama, J. Maruyama, K. Kitamoto
  • Appl. Microbiol. Biotechnol., 100, 9163-9174 (2016)
  • Molecular dissection of SO (SOFT) protein in stress-induced aggregation and cell-to-cell interactive functions in filamentous fungal multicellularity
  • W. Tsukasaki, K. Saeki, T. Katayama, J. Maruyama, K. Kitamoto
  • Fungal Biol., 120, 775-782 (2016)
  • Development of a genome editing technique using the CRISPR/Cas9 system in the industrial filamentous fungus Aspergillus oryzae
  • T. Katayama, Y. Tanaka, T. Okabe, H. Nakamura, W. Fujii, K. Kitamoto, J. Maruyama
  • Biotechnol. Lett., 38, 637-642 (2016)
  • AoRim15 is involved in conidial stress tolerance, conidiation and sclerotia formation in the filamentous fungus Aspergillus oryzae
  • H. Nakamura, T. Kikuma, F. J. Jin, J. Maruyama, K. Kitamoto
  • J. Biosci. Bioeng., 121, 365-371 (2016)
2015年
  • Expression, purification, refolding, and enzymatic characterization of two secretory phospholipases A2 from Neurospora crassa
  • Takayanagi, A., Miyakawa, T., Asano, A., Ohtsuka, J., Tanokura, M., and Arioka, M.
  • Protein Expr. Purif. 115, 69–75 (2015)
  • Functional analysis of AoAtg11 in selective autophagy in the filamentous fungus Aspergillus oryzae
  • T. Tadokoro, T. Kikuma, K. Kitamoto
  • Fungal Biol., 119, 560-567 (2015)
  • Modulating ER-Golgi cargo receptors for improving secretion of carrier-fused heterologous proteins in the filamentous fungus Aspergillus oryzae
  • H. Hoang, J. Maruyama, K. Kitamoto
  • Appl. Environ. Microbiol., 81,533-543 (2015)
2014年
  • The GH26 β-mannanase RsMan26H from a Symbiotic Protist of the Termite Reticulitermes speratus is an endo-Processive Mannobiohydrolase: Heterologous Expression and Characterization
  • H. Tsukagoshi, A. Nakamura, T. Ishida, M. Otagiri, S. Moriya, M. Samejima, K. Igarashi, K. Kitamoto, M. Arioka
  • Biochem. Biophys. Res. Commun., 452, 520-525 (2014)
  • Aspergillus oryzae CsyB catalyzes the condensation of two β-ketoacyl-CoAs to form 3-acetyl-6-alkyl-α-pyrone
  • M. Hashimoto, T. Koen, H. Takahashi, C, Suda, K. Kitamoto, I. Fujii
  • J. Biol. Chem., 289, 19976-19984 (2014)
  • A large non-conserved region of the tethering protein Leashin is involved in regulating the position, movement and function of Woronin bodies in Aspergillus oryzae
  • P. Han, F. J. Jin, J. Maruyama, K. Kitamoto
  • Eukaryot. Cell, 13, 866-877 (2014)
  • Structural and biochemical analyses of glycoside hydrolase family 26 beta-mannanase from a symbiotic protist of the termite Reticulitermes speratus
  • H. Tsukagoshi, A. Nakamura, T. Ishida, K.K. Touhara, M. Otagiri, S. Moriya, M. Samejima, K. Igarashi, S. Fushinobu, K. Kitamoto, M. Arioka
  • J. Biol. Chem., 289, 10843-10852 (2014)
  • Establishment of a new method to quantitatively evaluate hyphal fusion ability in Aspergillus oryzae
  • W. Tsukasaki, J. Maruyama, K. Kitamoto
  • Biosci. Biotechnol. Biochem., 78, 1254-62 (2014)
  • Efficient formation of heterokaryotic sclerotia in the filamentous fungus Aspergillus oryzae
  • R. Wada, F. J. Jin, Y. Koyama, J. Maruyama, K. Kitamoto
  • Appl. Microbiol. Biotechnol., 98, 325-334 (2014)
2013年
  • Aspergillus oryzae type Ⅲ polyketide synthase CsyB uses a fatty acyl starter for the biosynthesis of csypyrone B compounds
  • M. Hashimoto, S. Ishida, Y. Seshime, K. Kitamoto, I. Fujii
  • Bioorganic & Medicinal Chemistry Letters, 23, 5637–5640 (2013)
  • Aspergillus oryzae AoSO Is a novel component of stress granules upon heat stress in filamentous fungi
  • H.-T. Huang, J. Maruyama, K. Kitamoto
  • PLoS ONE, 8, e72209 (2013)
  • A novel glucose-tolerant β-glucosidase from the salivary gland of the termite Nasutitermes takasagoensis.
  • C. A. Uchima, G.Tokuda, H. Watanabe, K. Kitamoto, M. Arioka
  • J. Gen. Appl. Microbiol., 59, 141-145 (2013)
  • Lysophosphatidylcholine enhances NGF-induced MAPK and Akt signals through the extracellular domain of TrkA in PC12 cells
  • Wuhanqimuge, A. Itakura, Y. Matsuki, M. Tanaka, M. Arioka
  • EBS Open Bio, 3, 243–251 (2013)
  • Enhanced production of bovine chymosin by autophagy deficiency in the filamentous fungus Aspergillus oryzae
  • J. Yoon, T. Kikuma, J. Maruyama, K. Kitamoto
  • PLoS ONE, 8, e62512 (2013)
  • Functional analysis of Abp1p-interacting proteins involved in endocytosis of the MCC component in Aspergillus oryzae
  • K. Matsuo, Y. Higuchi, T. Kikuma, M. Arioka, K. Kitamoto
  • Fungal Genet. Biol., 56, 125-134 (2013)
  • Further enhanced production of heterologous proteins by double-gene disruption (ΔAosedD ΔAovps10) in a hyper-producing mutant of Aspergillus oryzae
  • L. Zhu, J. Maruyama, K. Kitamoto
  • Appl. Microbiol. Biotechnol., 97, 6347-6357 (2013)
  • Identification of Csypyrone B2 and B3 as the minor products of Aspergillus oryzae type III polyketide synthase CsyB
  • M. Hashimoto, Y. Seshime, K. Kitamoto, N. Uchiyama, Y. Goda, I. Fujii
  • Bioorganic & Medicinal Chemistry Letters, 23, 650-653 (2013)
  • Heterologous expression and characterization of a glycoside hydrolase family 45 endo-beta-1,4-glucanase from a symbiotic protist of the lower termite, Reticulitermes speratus
  • M. Otagiri, C. M. Lopez, K. Kitamoto, M. Arioka, T. Kudo, S. Moriya
  • Appl. Biochem. Biotechnol., 169, 1910-1918 (2013)
  • Functional analysis of Aoatg1 and detection of the Cvt pathway in Aspergillus oryzae
  • S. Yanagisawa, T. Kikuma, K. Kitamoto
  • FEMS Microbiol. Lett., 338, 168-176 (2013)
2012年
  • Hyphal heterogeneity in Aspergillus oryzae is the result of dynamic closure of septa by Woronin bodies
  • R. J. Bleichrodt, G. J. van Veluw, B. Recter, J. Maruyama, K. Kitamoto, H. A. Wösten
  • Mol Microbiol., 86, 1334-1344 (2012)
  • The Aspergillus nidulans MAPK Module AnSte11-Ste50-Ste7-Fus3 Controls Development and Secondary Metabolism
  • Ö. Bayram, Ö. S. Bayram, Y. L. Ahmed, J. Maruyama, O. Valerius, S. O. Rizzoli, R. Ficner, S. Irniger, G. H. Braus
  • PLoS Genet., 8, e1002816 (2012)
  • Contribution ratios of amyA, amyB, amyC genes to high-level α-amylase expression in Aspergillus oryzae
  • T. Nemoto, J. Maruyama, K. Kitamoto
  • Biosci. Biotechnol. Biochem., 76, 1477-1483 (2012)
  • Heterologous expression in Pichia pastoris and characterization of an endogenous thermostable and high-glucose-tolerant-glucosidase from the termite Nasutitermes takasagoensis
  • C. A. Uchima, G. Tokuda, H. Watanabe, K. Kitamoto, M. Arioka
  • Appl. Environ. Microbiol., 78, 4288-4293 (2012)
  • Expression and one-step purification of recombinant proteins using an alternative episomal vector for the expression of N-tagged heterologous proteins in Pichia pastoris
  • C. A. Uchima, M. Arioka
  • Biosci. Biotechnol. Biochem., 76, 368-371 (2012)
  • Improved heterologous protein production by a tripeptidyl peptidase gene (AosedD) disruptant of the filamentous fungus Aspergillus oryzae
  • L. Zhu, T. Nemoto, J. Yoon, J. Maruyama, K. Kitamoto
  • J. Gen. Appl. Microbiol., 58, 199-209 (2012)
  • Presence and functionality of mating-type genes in the supposedly asexual filamentous fungus Aspergillus oryzae
  • R. Wada, J. Maruyama, H. Yamaguchi, N. Yamamoto, Y. Wagu, M. Paoletti, D. B. Archer, P. S. Dyer, K. Kitamoto
  • Appl. Environ. Microbiol., 78, 2819-2829 (2012)
2011年
  • Whole-Genome Sequencing of Sake Yeast Saccharomyces cerevisiae Kyokai no. 7
  • T. Akao, I. Yashiro, A. Hosoyama, H. Kitagaki, H. Horikawa, D. Watanabe, R. Akada, Y. Ando, S. Harashima, T. Inoue, Y. Inoue, S. Kajiwara, K. Kitamoto, N. Kitamoto, O. Kobayashi, S. Kuhara, T. Masubuchi, H. Mizoguchi, Y. Nakao, A. Nakazato, M. Namise, T. Oba, T. Ogata, A. Ohta, M. Sato, S. Shibasaki, Y. Takatsume, S. Tanimoto, H. Tsuboi, A. Nishimura, K. Yoda, T. Ishikawa, K. Iwashita, N. Fujita, and H. Shimoi
  • DNA Res., 18, 423-434 (2011)
  • Peroxisomes are involved in biotin biosynthesis in Aspergillus and Arabidopsis
  • Y. Tanabe, J. Maruyama, S. Yamaoka, D. Yahagi, I. Matsuo, N. Tsutsumi, K. Kitamoto
  • J. Biol. Chem., 286, 30455-30461 (2011)
  • A carrier fusion significantly induces unfolded protein response in heterologous protein production by Aspergillus oryzae
  • A. Ohno, J. Maruyama, T. Nemoto, M. Arioka, K. Kitamoto
  • Appl. Microbiol. Biotechnol., 92, 1197-1206 (2011)
  • Genetic Safeguard against Mycotoxin Cyclopiazonic Acid Production in Aspergillus oryzae
  • N. Kato, M. Tokuoka, Y. Shinohara, M. Kawatani, M. Uramoto, Y. Seshime, I. Fujii, K. Kitamoto, T. Takahashi, S. Takahashi, Y. Koyama, H. Osada
  • Chembiochem, 12, 1376-1382 (2011)
  • Septum-directed secretion in the filamentous fungus Aspergillus oryzae
  • Y. Hayakawa, E. Ishikawa, J. Shoji, H. Nakano, K. Kitamoto
  • Mol. Microbiol., 81, 40-55 (2011)
  • SclR, a basic helix-loop-helix transcription factor, regulates hyphal morphology and promotes sclerotial formation in Aspergillus oryzae
  • F. J. Jin, T. Takahashi, K. Matsushima, S. Hara, Y. Shinohara, J. Maruyama, K. Kitamoto, Y. Koyama
  • Eukaryot. Cell, 10, 945-955 (2011)
  • Functional analysis of the putative AAA ATPase AipA localizing at the endocytic sites in the filamentous fungus Aspergillus oryzae
  • Y. Higuchi, M. Arioka, K. Kitamoto
  • FEMS Microbiol. Lett., 320, 63-71 (2011)
  • Autophagy delivers misfolded secretory proteins accumulated in endoplasmic reticulum to vacuoles in the filamentous fungus Aspergillus oryzae
  • S. Kimura, J. Maruyama, T. Kikuma, M. Arioka, K. Kitamoto
  • Biochem. Biophys. Res. Commun., 406, 464-470 (2011)
  • Functional analysis and subcellular location of two flavohemoglobins from Aspergillus oryzae
  • S. Zhou, S. Fushinobu, S. W. Kim, Z. Zhou, Y. Nakanishi, J. Maruyama, K. Kitamoto, T. Wakagi, H. Shoun
  • Fungal Genet. Biol., 48, 200-207 (2011)
  • Heterologous expression and characterization of a glucose-stimulated β-glucosidase from the termite Neotermes koshunensis in Aspergillus oryzae
  • C. A. Uchima, G. Tokuda, H. Watanabe, K. Kitamoto, M. Arioka
  • Appl. Microbiol. Biotechnol., 89, 1761-71 (2011)
  • Disruption of ten protease genes in the filamentous fungus Aspergillus oryzae highly improves production of heterologous proteins
  • J. Yoon, J. Maruyama, K. Kitamoto
  • Appl. Microbiol. Biotechnol., 89, 747-759 (2011)
  • High-throughput recombinant gene expression systems in Pichia pastoris using newly developed plasmid vectors
  • T. Sasagawa, M. Matsui, Y. Kobayashi, M. Odagiri, S. Moriya, Y. Sakamoto, Y. Ito, C. C. Lee, K. Kitamoto, M. Arioka
  • Plasmid, 65, 65-69 (2011)
  • Analysis of autophagy in Aspergillus oryzae by disruption of Aoatg13, Aoatg4, and Aoatg15 genes
  • T. Kikuma, K. Kitamoto
  • FEMS Microbiol. Lett., 316, 61-69 (2011)
2010年
  • Macroautophagy-mediated degradation of whole nuclei in the filamentous fungus Aspergillus oryzae
  • J. Shoji, T. Kikuma, M. Arioka, K. Kitamoto
  • PLoS ONE, 5, e15650 (2010)
  • In vivo imaging of endoplasmic reticulum and distribution of mutant α-amylase in Aspergillus oryzae
  • S. Kimura, J. Maruyama, T. Watanabe, Y. Ito, M. Arioka, K. Kitamoto
  • Fungal Genet. Biol., 47, 1044-1054 (2010)
  • Purification and characterization of termite endogenous beta-1,4-Endoglucanases produced in Aspergillus oryzae
  • K. Hirayama, H. Watanabe, G. Tokuda, K. Kitamoto, M. Arioka
  • Biosci. Biotechnol. Biochem., 74, 1680-1686 (2010)
  • Aspergillus oryzae type III polyketide synthase CsyA is involved in the biosynthesis of 3,5-dihydroxybenzoic acid
  • Y. Seshime, P. R. Juvvadi, K. Kitamoto, Y. Ebizuka, T. Nonaka, I. Fujii
  • Bioorg. Med. Chem. Lett., 20, 4785-4788 (2010)
  • Enhanced production and secretion of heterologous proteins by the filamentous fungus Aspergillus oryzae via disruption of vacuolar protein sorting receptor gene Aovps10
  • J. Yoon, T. Aishan, J. Maruyama, K. Kitamoto
  • Appl. Environ. Microbiol., 76, 5718-5727 (2010)
  • A Eukaryotic Copper-Containing Nitrite Reductase Derived from a NirK Homolog Gene of Aspergillus oryzae
  • Y. Nakanishi, S. Zhou, S. W. Kim, S. Fushinobu, J. Maruyama, K. Kitamoto, T. Wakagi, H. Shoun
  • Biosci. Biotechnol. Biochem., 74, 984-991 (2010)
  • Identification of csypyrone B1 as the novel product of Aspergillus oryzae type III polyketide synthase CsyB
  • Y. Seshime, P. R. Juvvadi, K. Kitamoto, Y. Ebizuka, I. Fujii
  • Bioorganic & Medicinal Chemistry Letters, 18, 4542-4546 (2010)
  • Promotion of efficient Saccharification with Aspergillus fumigatus AfSwo1 towards crystalline cellulose
  • X. Chen, N. Ishida, N. Todaka, R. Nakamura, J. Maruyama, H. Takahashi, K. Kitamoto
  • Appl. Environ. Microbiol., 76, 2556-2561 (2010)
  • AoSO protein accumulates at the septal pore in response to various stresses in the filamentous fungus Aspergillus oryzae
  • J. Maruyama, C. S. Escano, K. Kitamoto
  • Biochem. Biophys. Res. Commun., 391, 868-873 (2010)
  • Distinct enzymatic and cellular characteristics of two secretory phospholipases A(2) in the filamentous fungus Aspergillus oryzae
  • T. Nakahama, Y. Nakanishi, A. R. Viscomi, K. Takaya, K. Kitamoto, S. Ottonello, M. Arioka
  • Fungal Genet. Biol., 47, 318-331 (2010)
  • Heterologous expression and characterization of an endoglucanase from a symbiotic protist of the lower termite, Reticulitermes speratus
  • N. Todaka, C. M. Lopez, T. Inoue, K. Saita, J. Maruyama, M. Arioka, K. Kitamoto, T. Kudo, S. Moriya
  • Appl. Biochem. Biotechnol., 160, 1168-1178 (2010)
2009年
  • A cytosolic phospholipase A(2)-like protein in the filamentous fungus Aspergillus oryzae localizes to the intramembrane space of the mitochondria
  • K. Takaya, Y. Higuchi, K. Kitamoto, M. Arioka
  • FEMS Microbiol. Lett., 301, 201-209 (2009)
  • Improvement of heterologous protein production in Aspergillus oryzae by RNA interference of α-amylase genes
  • T. Nemoto, J. Maruyama, K. Kitamoto
  • Biosci. Biotech. Biochem., 73, 2370-2373 (2009)
  • Using a new GPI-anchored-protein identification system to mine the protein databases of Aspergillus fumigatus, Aspergillus nidulans, and Aspergillus oryzae
  • W. Cao, J. Maruyama, K, Kitamoto, K. Sumikoshi, T. Terada, S. Nakamura, K. Shimizu
  • J. Gen. Appl. Microbiol., 55, 381-393 (2009)
  • Genetic analysis of glucosidase II beta-subunit in trimming of high-mannose-type glycans
  • T. Watanabe, K. Totani, I. Matsuo, J. Maruyama, K. Kitamoto, Y. Ito
  • lycobiology, 19, 834-840 (2009)
  • Functional expression of the Aspergillus flavus PKS-NRPS hybrid CpaA involved in the biosynthesis of cyclopiazonic acid
  • Y. Seshime, P. R. Juvvadi, M. Tokuoka, Y. Koyama, K. Kitamoto, Y. Ebizuka, I. Fujii
  • Bioorganic & Medicinal Chemistry Letters, 19, 3288-3292 (2009)
  • Cloning of Aspergillus oryzae Aovps5 gene, homologous to vacuolar protein sorting associated gene VPS5 and construction of the disruptant
  • C. Tokunaga, C. Saitoh, K. Kitamoto
  • J. Biosci. Bioeng., 108, 121-123 (2009)
  • Disruption of the Aopex11-1 gene involved in peroxisome proliferation leads to impaired Woronin body formation in Aspergillus oryzae
  • C. S. Escano, P. R. Juvvadi, F. J. Jin, T. Takahashi, Y. Koyama, S. Yamashita, J. Maruyama, K. Kitamoto
  • Eukaryot. Cell, 8, 296-305 (2009)
  • Isolation of Aspergillus oryzae mutants for heterologous protein production from a double proteinase gene disruptant
  • T. Nemoto, T. Watanabe, Y. Mizogami, J. Maruyama, K. Kitamoto
  • Appl. Microbiol. Biotechnol., 82, 1105-1114 (2009)
  • Construction of quintuple protease gene disruptant for heterologous protein production in Aspergillus oryzae
  • J. Yoon, S. Kimura, J. Maruyama, K. Kitamoto
  • Appl. Microbiol. Biotechnol., 82, 691-701 (2009)
  • Endocytosis is crucial for cell polarity and apical membrane recycling in the filamentous fungus Aspergillus oryzae
  • Y. Higuchi, J. Shoji, M. Arioka, K. Kitamoto
  • Eukaryot. Cell, 8, 37-46 (2009)
  • Lysophosphatidylcholine protects cerebellar granule neurons from apoptotic cell death
  • Y. Ikeno, S. H. Cheon, N. Konno, A. Nakamura, K. Kitamoto, M. Arioka
  • J. Neurosci. Res., 87, 190-199 (2009)
2008年
  • Codon optimization prevents premature polyadenylation of heterologously-expressed termite cellulases in Aspergillus oryzae and contributes to their improved production
  • S. Sasaguri, J. Maruyama, S. Moriya, T. Kudo, K. Kitamoto, M. Arioka
  • J. Gen. Appl. Microbiol., 54, 343-351 (2008)
  • Identification of a novel polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) gene required for the biosynthesis of cyclopiazonic acid in Aspergillus oryzae
  • M. Tokuoka, Y. Seshime, I. Fujii, K. Kitamoto, Y. Koyama
  • Fungal Genet. Biol., 45, 1608-1615 (2008)
  • Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis Inducing Factor (AIF)-like mitochondrial oxidoreductase
  • M. Savoldi, I. Malavazi, F. M. Soriani, J. L. Capellaro, K. Kitamoto, M. E. da Silva Ferreira, M. H. Goldman, G. H. Goldman.
  • Mol. Microbiol., 70, 44-59 (2008)
  • Multiple gene disruptions by marker recycling with highly efficient gene-targeting background (ΔligD) in Aspergillus oryzae
  • J. Maruyama, K. Kitamoto
  • Biotechnol. Lett., 30, 1811-1817 (2008)
  • Acid-induced sweetness of neoculin is ascribed to its pH-dependent agonistic-antagonistic interaction with human sweet taste receptor
  • K. Nakajima, Y. Morita, A. Koizumi, T. Asakura, T. Terada, K. Ito, A. Shimizu-Ibuka, J. Maruyama, K. Kitamoto, T. Misaka, K. Abe.
  • FASEB J., 22, 2323-2330 (2008)
  • Monitoring Global Gene Expression of Proteases and Improvement of Human Lysozyme Production in the nptB Gene Disruptant of Aspergillus oryzae
  • S. Kimura, J. Maruyama, M. Takeuchi, K. Kitamoto
  • Biosci. Biotech. Biochem., 72, 499-502 (2008)
2007年
  • Novel neurotrophic effects of sphingosylphosphorylcholine in cerebellar granule neurons and in PC12 cells
  • N. Konno, A. Nakamura, Y. Ikeno, S. H. Cheon, K. Kitamoto, M. Arioka
  • Biochem. Biophys. Res. Commun., 364, 163-168 (2007)
  • Aggregation of endosomal-vacuolar compartments in the Aovps24-deleted strain in the filamentous fungus Aspergillus oryzae
  • A. Tatsumi, J. Shoji, T. Kikuma, M. Arioka, K. Kitamoto
  • Biochem. Biophys. Res. Commun., 362, 474-479 (2007)
  • Identification and characterization of an intracellular lectin, calnexin, from Aspergillus oryzae using N-glycan-conjugated beads
  • T. Watanabe, I. Matsuo, J. Maruyama, K. Kitamoto, Y. Ito
  • Biosci. Biotech. Biochem., 71, 2688-2696 (2007)
  • Elevated expression of genes under the control of stress response element (STRE) and Msn2p in an ethanol tolerance sake yeast Kyokai no.11
  • M. Watanabe, K. Tamura, J. P. Magbanua, K. Takano, K. Kitamoto, H. Kitagaki, T. Akao, and H. Shimoi
  • J. Biosci. Bioeng., 104, 163-170 (2007)
  • Double disruption of the proteinase genes, tppA and pepE, increases the production level of human lysozyme by Aspergillus oryzae
  • F. J. Jin, T. Watanabe, P. R. Juvvadi, J. Maruyama, M. Arioka, K. Kitamoto
  • Appl. Microbiol. Biotechnol., 76, 1059-1068 (2007)
  • Microbial Production of Sensory-active Miraculin
  • K. Ito, T. Asakura, Y. Morita, K. Nakajima, A. Koizum, A. Shimizu-Ibuka, K. Masuda, M. Ishiguro, T. Terada, J. Maruyama, K. Kitamoto, T. Misaka, K. Abe
  • Biochem. Biophys. Res. Commun., 360, 407-411 (2007)
  • Light represses conidiation in Koji mold Aspergillus oryzae
  • R. Hatakeyama, T. Nakahama, Y. Higuchi, K. Kitamoto
  • Biosci. Biotech. Biochem., 71, 1844-1849 (2007)
  • Systematic analysis of SNARE localization in the filamentous fungus Aspergillus oryzae
  • M. Kuratsu, A. Taura, J. Shoji, S. Kikuchi, M. Arioka, K. Kitamoto
  • Fungal Genet. Biol., 44, 1310-1323 (2007)
  • Phosphorylation of the Aspergillus oryzae Woronin body protein, AoHex1, by protein kinase C: evidences for its role in the multimerization and proper localization of the Woronin body protein
  • P. R. Juvvadi, J. Maruyama, K. Kitamoto
  • Biochem. J., 405, 533-540 (2007)
  • Analysis of expressed sequence tags from the fungus Aspergillus oryzae cultured under different conditions
  • T. Akao, M. Sano, O. Yamada, T. Akeno, K. Fujii, K. Goto, S. Ohashi-Kunihiro, K. Takase, M. Yasukawa-Watanabe, K. Yamaguchi, Y. Kurihara, J. Maruyama, P. R. Juvvadi, A. Tanaka, Y. Hata, Y. Koyama, S. Yamaguchi, N. Kitamoto, K. Gomi, K. Abe, M. Takeuchi, T. Kobayashi, H. Horiuchi, K. Kitamoto, Y. Kashiwagi, M. Machida, O. Akita
  • DNA Res., 14, 47-57 (2007)
  • Lysophosphatidylcholine mediates melanocyte dendricity through PKCζ activation
  • G. A. Scott, M. Arioka, S. E. Jacobs
  • J. Invest. Dermatol., 127, 668-675 (2007)
2006年
Aspergillus 関連
  • Aovps24, a homologue of VPS24, is required for vacuolar formation which could maintain proper growth and development in the filamentous fungus Aspergillus oryzae
  • A. Tatsumi, T. Kikuma, M. Arioka, K. Kitamoto
  • Biochem. Biophys. Res. Commun., 347,970-978 (2006)
  • Functional analysis of the ATG8 homologue Aoatg8, and role of autophagy in differentiation and germination in Aspergillus oryzae
  • T. Kikuma, M. Ohneda, M. Arioka, K. Kitamoto
  • Eukaryot. Cell, 5, 1328-1336 (2006)
  • Development of a versatile expression plasmid construction system for Aspergillus oryzae and its application to visualization of mitochondria
  • Y. Mabashi, T. Kikuma, J. Maruyama, M. Arioka , K. Kitamoto
  • Biosci. Biotech. Biochem., 70, 1882-1889 (2006)
  • Extracellular production of neoculin, a sweet-tasting heterodimeric protein with taste-modifying activity, by Aspergillus oryzae
  • K. Nakajima, T. Asakura, J. Maruyama, Y. Morita, H. Oike, A. Shimizu-Ibuka, T. Misaka, H. Sorimachi, S. Arai, K. Kitamoto, K. Abe
  • Appl. Environ. Microbiol., 72, 3716-3723 (2006)
  • Square-plate culture method allows detection of differential gene expression and screening of novel, region-specific genes in Aspergillus oryzae
  • K. Masai, J. Maruyama, K. Sakamoto, H. Nakajima, O. Akita, K. Kitamoto
  • Appl. Microbiol. Biotechnol., 71, 881-891 (2006)
  • Visualization of the endocytic pathway in the filamentous fungus Aspergillus oryzae using an EGFP-fused plasma membrane protein
  • Y. Higuchi, T. Nakahama, J. Shoji, M. Arioka, K. Kitamoto
  • Biochem. Biophys. Res. Commun., 340, 784-791 (2006)
  • Vacuolar membrane dynamics in the filamentous fungus Aspergillus oryzae
  • J. Shoji, M. Arioka, K. Kitamoto
  • Eukaryot. Cell, 5, 411-421 (2006)
  • Differential distribution of endoplasmic reticulum network as visualized by the BipA-EGFP fusion protein in hyphal compartments across the septum of the filamentous fungus, Aspergillus oryzae
  • J. Maruyama, S. Kikuchi, K. Kitamoto
  • Fungal Genet. Biol., 43, 642-654 (2006)
Yeast 関連
  • Metabolic engineering of Saccharomyces cerevisiae for efficient production of pure L-(+)-lactic acid
  • N. Ishida, S. Saitoh, T. Onishi, K. Tokuhiro, E. Nagamori, K. Kitamoto, H. Takahashi
  • Appl. Biochem. Biotechnol., 131, 795-807 (2006)
  • The effect of pyruvate decarboxylase gene knockout in Saccharomyces cerevisiae on L-lactic acid production
  • N. Ishida, S. Saitoh, T. Onishi, K. Tokuhiro, E. Nagamori, K. Kitamoto, H. Takahashi
  • Biosci. Biotech. Biochem., 70, 1148-1153 (2006)
  • D-lactic acid production by metabolically engineered Saccharomyces cerevisiae
  • N. Ishida, K. Tokuhiro, E. Nagamori, T. Onishi, S. Saitoh, K. Kitamoto, H. Takahashi
  • J. Biosci. Bioeng., 101, 172-177 (2006)
sPLA2関連
  • Lysophosphatidylcholine mediates melanocyte dendricity through PKCzeta activation
  • G. A. Scott, M. Arioka, S. E. Jacobs
  • J. Invest. Dermatol. 127(3), 668-675 (2006)
2005年
Aspergillus 関連
  • Genome sequencing and analysis of Aspergillus oryzae
  • M. Machida, K. Asai, M. Sano, T. Tanaka, T. Kumagai, G. Terai, K. Kusumoto, T. Arima, O. Akita, Y. Kashiwagi, K. Abe, K. Gomi, H. Horiuchi, K. Kitamoto, T. Kobayashi, M. Takeuchi, D. W. Denning, J. E. Galagan, W. C. Nierman, J. Yu, D. B. Archer, J. W. Bennett, D. Bhatnagar, T. E. Cleveland, N. D. Fedorova, O. Gotoh, H. Horikawa, A. Hosoyama, M. Ichinomiya, R. Igarashi, K. Iwashita, P. Rao Juvvadi, M. Kato, Y. Kato, T. Kin, A. Kokubun, H. Maeda, N. Maeyama, J. Maruyama, H. Nagasaki, T. Nakajima, K. Oda, K. Okada, I. Paulsen, K. Sakamoto, T. Sawano, M. Takahashi, K. Takase, Y. Terabayashi, J. Wortman, O. Yamada, Y. Yamagata, H. Anazawa, Y. Hata, Y. Koide, T. Komori, Y. Koyama, T. Minetoki, S. Suharnan, A. Tanaka, K. Isono, S. Kuhara, N. Ogasawara and H. Kikuchi
  • Nature, 438, 1157-1161 (2005)
  • Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
  • W. C. Nierman, A. Pain, M. J. Anderson, J. R. Wortman, H. S. Kim, J. Arroyo, M. Berriman, K. Abe, D. B. Archer, C. Bermejo, J. Bennett, P. Bowyer, D. Chen, M. Collins, R. Coulsen, R. Davies, P. S. Dyer, M. Farman, N. Fedorova, N. Fedorova, T. V. Feldblyum, R. Fischer, N. Fosker, A. Fraser, J. L. Garcia, M. J. Garcia, A. Goble, G. H. Goldman, K. Gomi, S. Griffith-Jones, R. Gwilliam, B. Haas, H. Haas, D. Harris, H. Horiuchi, J. Huang, S. Humphray, J. Jimenez, N. Keller, H. Khouri, K. Kitamoto, T. Kobayashi, S. Konzack, R. Kulkarni, T. Kumagai, A. Lafton, J. P. Latge, W. Li, A. Lord, C. Lu, W. H. Majoros, G. S. May, B. L. Miller, Y. Mohamoud, M. Molina, M. Monod, I. Mouyna, S. Mulligan, L. Murphy, S. O'neil, I. Paulsen, M. A. Penalva, M. Pertea, C. Price, B. L. Pritchard, M. A. Quail, E. Rabbinowitsch, N. Rawlins, M. A. Rajandream, U. Reichard, H. Renauld, G. D. Robson, S. R. de Cordoba, J. M. Rodriguez-Pena, C. M. Ronning, S. Rutter, S. L. Salzberg, M. Sanchez, J. C. Sanchez-Ferrero, D. Saunders, K. Seeger, R. Squares, S. Squares, M. Takeuchi, F. Tekaia, G. Turner, C. R. de Aldana, J. Weidman, O. White, J. Woodward, J. H. Yu, C. Fraser, J. E. Galagan, K. Asai, M. Machida, N. Hall, B. Barrell, D. W. Denning.
  • Nature, 438, 1151-1156 (2005)
  • Genomic evidences for the existence of a phenylpropanoid metabolic pathway in Aspergillus oryzae
  • Y. Seshime, P. R. Juvvadi, I. Fujii, K. Kitamoto
  • Biochem. Biophys. Res. Commun., 337, 747-751 (2005)
  • Development of a modified positive selection medium that allows to isolate Aspergillus oryzae strains cured of the integrated niaD-based plasmid
  • K. Ishi, T. Watanabe, P. R. Juvvadi, J. Maruyama, K. Kitamoto
  • Biosci. Biotech. Biochem., 69, 2463-2465 (2005)
  • Three-dimensional image analysis of plugging at the septal pore by Woronin body during hypotonic shock inducing hyphal tip bursting in Aspergillus oryzae
  • J. Maruyama, P. R. Juvvadi, K. Ishi, K. Kitamoto
  • Biochem. Biophys. Res. Commun. 331, 1081-1088 (2005)
  • Discovery of a novel superfamily of type III polyketide synthases in Aspergillus oryzae
  • Y. Seshime, P. R. Juvvadi, I. Fujii, K. Kitamoto
  • Biochem. Biophys. Res. Commun., 331, 253-260 (2005)
  • Isolation and characterization of Aspergillus oryzae vacuolar protein sorting mutants
  • M. Ohneda, M. Arioka, K. Kitamoto
  • Appl. Environ. Microbiol., 71, 4856-4861 (2005)
  • Development of Aspergillus oryzae thiA promoter as a tool for molecularbiological studies
  • J. Shoji, J. Maruyama, M. Arioka, K. Kitamoto
  • FEMS Microbiology Letters, 244, 41-46 (2005)
  • Visualizing Nuclear Migration during Conidiophore Development in Aspergillus nidulans and Aspergillus oryzae: Multinucleation of Conidia Occurs through Direct Migration of Plural Nuclei from Phialides and Confers Greater Viability and Early Germination in Aspergillus oryzae
  • K. Ishi, J. Maruyama, P. R. Juvvadi, H. Nakajima, K. Kitamoto
  • Biosci. Biotech. Biochem., 69, 747-754 (2005)
Yeast 関連
  • Vacuolar H+-ATPase and plasma membrane H+-ATPase contribute to the tolerance against high-pressure carbon dioxide treatment in Saccharomyces cerevisiae
  • T. Watanabe, S. Furukawa, K. Kitamoto, A. Takatsuki, R. Hirata, H. Ogihara, M. Yamasaki
  • Int. J. Food Microbiol., 105, 131-137 (2005)
  • Efficient production of L-lactic acid by metabolically engineered Saccharomyces cerevisiae with a genome-integrated L-lactate dehydrogenase gene
  • N. Ishida, S. Saitoh, K. Tokuhiro, E. Nagamori, T. Matsuyama, K. Kitamoto, H. Takahashi
  • Appl. Environ. Microbiol., 71, 1964-1970 (2005)
  • Genetically engineered wine yeast produced a high concentration of L-lactic acid of extremely high optical purity
  • S. Saitoh, N. Ishida, K. Onishi, T. Tokuhiro, E. Nagamori, K. Kitamoto, H. Takahashi
  • Appl. Environ. Microbiol., 71, 2789-2792 (2005)
  • Identification and characterization of rns4/vps32 mutation in the RNase T1 expression sensitive strain of Saccharomyces cerevisiae: Evidence for altered ambient response resulting in transportation of the secretory protein to vacuoles
  • K. Unno, P. R. Juvvadi, H. Nakajima, K. Shirahige, K. Kitamoto
  • FEMS Yeast Research, 5, 801-812 (2005)
  • Isolation of Saccharomyces cerevisiae RNase T1 hypersentivie (rns) mutants and genetic analysis of the RNS1/DSL1 gene
  • T. Ishikawa, K. Unno, G. Nonaka, H. Nakajima, K. Kitamoto
  • J. Gen. Appl. Microbiol., 51, 73-82 (2005)
sPLA2関連
  • Secretory phospholipase A2 induces neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor
  • Y. Ikeno, N. Konno, S. H. Cheon, A. Bolchi, S. Ottonello, K. Kitamoto, M. Arioka
  • J. Biol. Chem., 280, 28044-28052 (2005)
  • Neuronal expression and neuritogenic action of group X secreted phospholipase A2
  • S. Masuda, M. Murakami, Y. Takanezawa, J. Aoki, H. Arai, Y. Ishikawa, T. Ishii, M. Arioka, I. Kudo
  • J. Biol. Chem., 17, 280, 23203-23214 (2005)
  • A novel neurotrophic role of secretory phospholipases A2 for cerebellar granule neurons
  • M. Arioka, S. H. Cheon, Y. Ikeno, S. Nakashima, K. Kitamoto
  • FEBS Lett., 579, 2693-2701 (2005)
その他
  • Design and synthesis of oligosaccharides that interfere with glycoprotein quality control system
  • M. A. Arai, I. Matsuo, S. Hagihara, K. Totani, J. Maruyama, K. Kitamoto, Y. Ito
  • ChemBioChem, 6, 2281-2289 (2005)
  • SspA, an outer membrane protein, is highly induced under salt-stressed conditions and is essential for growth under salt-stressed aerobic conditions in Rhodobacter sphaeroides f. sp. denitrificans
  • M. Tsuzuki, X. Xu, K. Sato, M. Abo, M. Arioka, H. Nakajima, K. Kitamoto, A. Okubo
  • Appl. Microbiol. Biotechnol., 68, 242-250 (2005)
2004年
  • Development of a novel quadruple auxotrophic host transformation system by argB gene disruption using adeA gene and exploiting adenine auxotrophy in Aspergillus oryzae
  • F. J. Jin, J. Maruyama, P. R. Juvvadi, M. Arioka, K. Kitamoto
  • FEMS Microbiol. Letters, 239, 79-85 (2004)
  • Dibasic amino acid residues at the carboxy-terminal end of kinase homology domain participate in the plasma membrane localization and function of phosphatidylinositol 5-kinase gamma
  • M. Arioka, S. Nakashima, Y. Shibasaki, K. Kitamoto
  • Biochem. Biophys. Res. Commun., 319, 456-463 (2004)
  • The catalytic activity, but not receptor binding, of sPLA(2)s plays a critical role for neurite outgrowth induction in PC12 cells
  • S. Nakashima, K. Kitamoto, M. Arioka
  • Brain Res., 1015, 207-211 (2004)
  • Adenine auxotrophic mutants of Aspergillus oryzae: development of a noveltransformation system with triple auxotrophic hosts
  • F. J. Jin, J. Maruyama, P. R. Juvvadi, M. Arioka, K. Kitamoto
  • Biosci. Biotechnol. Biochem., 68, 656-662 (2004)
  • Molecular cloning and functional characterization of avaB, a gene encoding Vam6p/Vps39p-like protein in Aspergillus nidulans
  • M. Oka, J. Maruyama, M. Arioka, H. Nakajima, K. Kitamoto
  • FEMS Microbiol. Letters, 232, 113-121 (2004)
  • Effects of protein transport inhibitors on the distribution and secretion of the fusion protein the RntA-EGFP in Aspergillus oryzae
  • K. Masai, J. Maruyama, H. Nakajima, K. Kitamoto
  • Biosci. Biotech. Biochem., 68, 1569-1573 (2004)
2003年
  • Identification and characterization of Scp15, a protein from Streptomyces coelicolor A3(2) inducing neurites in PC12 cells
  • S. Nakashima, S. Wakatsuki, T. Yokoyama, M. Arioka, K. Kitamoto
  • Biosci. Biotechnol. Biochem., 67, 77-82 (2003)
  • Functional analysis of the calcineurin-encoding gene cnaA from Aspergillus oryzae: evidence for its putative role in stress adaptation
  • P. R. Juvvadi, Y. Kuroki, M. Arioka, H. Nakajima, K. Kitamoto
  • Arch. Microbiol., 179, 416-422 (2003)
  • In vivo visualization of the distribution of a secretory protein in Aspergillus oryzae hyphae using the RntA-EGFP fusion protein
  • K. Masai, J. Maruyama , H. Nakajima, K. Kitamoto
  • Biosci. Biotech. Biochem., 67, 455-459 (2003)
  • Cloning and overexpression of b -N-acetylglucosaminidase encoding gene nagA from Aspergillus oryzae and enzyme-catalyzed synthesis of human milk oligosaccharide
  • I. Matsuo, S. Kim, Y. Yamamoto, K. Ajisaka, J. Maruyama, H. Nakajima, K. Kitamoto
  • Biosci. Biotechnol. Biochem., 67, 646-650 (2003)
  • Novel role of cytoplasmic dynein motor in maintenance of the nuclear number in conidia through organized conidiation in Aspergillus oryzae
  • J. Maruyama, H. Nakajima, K. Kitamoto
  • Biochem. Biophys. Res. Commun., 307, 900-906 (2003)
  • Secretory phospholipases A2 induce neurite outgrowth in PC12 cells
  • S. Nakashima, Y. Ikeno, T. Yokoyama, M. Kuwana, A. Bolchi, S. Ottonello, K. Kitamoto, M. Arioka
  • Biochem. J., 376, 655-666 (2003)
2002年
  • Visualization of Vacuoles in Aspergillus oryzae by expression of CPY-EGFP
  • M. Ohneda, M. Arioka, H. Nakajima, K. Kitamoto
  • Fungal Genet. Biol., 37, 29-38 (2002)
  • Cloning, nucleotide sequencing, and expression of the β-galactosidase-encoding gene (lacA) from Aspergillus oryzae
  • Y. Ito, T. Sasaki, K. Kitamoto, C. Kumagai, K. Takahashi, K. Gomi, G. Tamura
  • J. Gen. Appl. Microbiol., 48, 135-142 (2002)
  • Observation of EGFP-visualized nuclei and distribution of vacuoles in Aspergillus oryzae arpA null mutant
  • J. Maruyama, H. Nakajima, K. Kitamoto
  • FEMS Microbiol. Letters, 206, 57-61 (2002)
  • Biochemical characterization of horA-independent hop resistance mechanism in Lactobacillus brevis
  • K. Suzuki, M. Sami, H. Kadokura, H. Nakajima, K. Kitamoto
  • Int. J. Food Microbiol., 76, 223-230 (2002)
  • Cloning and characterzation of vmaA, the gene encoding a 69-kDA catalytic subninit of the vacuolar H+-ATPase during pH mediated growth of Aspergillus oryzae
  • Y. Kuroki, P. R. Juvvadi, M. Arioka, H. Nakajima, K. Kitamoto
  • FEMS Microbiol. Letters, 209, 277-282 (2002)
  • Cloning and characterization of a gene (avaA) from Aspergillus nidulans encoding a small GTPase involved in vacuolar biogenesis
  • K. Ohsumi, M. Arioka, H. Nakajima, K. Kitamoto
  • Gene, 291, 77-84 (2002)
  • Cloning and characterization of the nagA gene that encodes b-N-acetylglucosaminidase from Aspergillus nidulans and its expression in Aspergillus oryzae.
  • S. Kim, I. Matsuo, K. Ajisaka, H. Nakajima, K. Kitamoto
  • Biosci. Biotechnol. Biochem., 66, 2168-2175 (2002)
  • Functional expression in Aspergillus oryzae of p15, a protein with potent neurite-inducing activity in PC12 cells
  • S. Nakashima, M. Arioka, K. Kitamoto
  • Biosci. Biotechnol. Biochem., 66, 674-678 (2002)
2001年
  • Cloning and characterization of Aspergillus nidulans vpsA gene which is involved in vacuolar biogenesis
  • Y. Tarutani, K. Ohsumi, M. Arioka, H. Nakajima, K. Kitamoto
  • Gene, 268, 23-30 (2001)
  • Metalloadsortption b Saccharomyces cerevisiae cells expressing invertase-metallothionein (Suc2-Cup1) fusion protein localized to the cells surface
  • H. Nakajima, T. iwasaki, K. Kitamoto
  • J. Gen. Appl. Microbiol., 47, 47-51 (2001)
  • Cloning and characterization of the cpyA gene encoding intracellular carboxypeptidase from Aspergillus nidulans
  • K. Ohsumi, Y. Matsuda, H. Nakajima, K. Kitamoto
  • Biosci. Biotech. Biochem., 65, 1175-1180 (2001)
  • Visualization of nuclei in Aspergillus oryzae with EGFP and analysis of the number of nuclei in each conidium by FACS
  • J. Maruyama, H. Nakajima, K. Kitamoto
  • Biosci. Biotech. Biochem., 65, 1504-1510 (2001)
  • Molecular cloning, functional expression and characterization of p15, a novel fungal protein with potent neurite-inducing activity in PC12 cells
  • S. Wakatsuki, T. Yokoyama, S. Nakashima, A. Nishimura, M. Arioka, K. Kitamoto
  • Biochim. Biophys. Acta, 1522, 74-81 (2001)
  • PIP kinase Ig is the major PI(4,5)P2 synthesizing enzyme at the synapse
  • M. R. Wenk, L. Pellegrini, V. A. Klenchin, G. Di Paolo, S. Chang, L. Daniell, M. Arioka, T. F. Martin, and P. De Camilli
  • Neuron 32(1), 79-88 (2001)
  • Efficient export of alkaline phosphatase overexpressed from a multicopy plasmid requires degP, a gene encoding a periplasmic protease of Escherichia coli
  • H. Kadokura, H. Kawasaki, K. Yoda, M. Yamasaki, K. Kitamoto
  • J. Gen. Appl. Microbiol., 47, 133-141 (2001)
  • Cloning and sequencing of a gene encoding a novel salt stress-induced membrane protein from Rhodobacter sphaeroides f. sp. Denitrificans
  • X. Y. Xu, H. Kadokura, A. Okubo, K. Kitamoto, S. Yamazaki
  • Appl. Microbiol. Biotechnol., 56,442-447 (2001)
  • Deletion analysis of the enosale gene (enoA) promoter from the filamentous fungus, Aspergillus oryzae
  • T. Toda, M. Sano, M. Honda, O. J. Rimoldi, Y. Ynag, M. Yamamoto, K. Takase, K. Hirozumi, K. Kitamoto, T. Minetoki, K. Gomi, M. Machida
  • Curr. Genet., 40, 260-267 (2001)
  • Cloning and sequence analysis of cnaA gene encoding the catalytic subunit of calcineurin from A. oryzae
  • P. R. Juvvadi, M. Arioka, H. Nakajima, K. Kitamoto
  • FEMS Microbiol. Letters, 204, 169-174 (2001)
2000年
  • Molecular breeding of yeast with higher metal-adsorption capacity by expression of histidine-repeat insertion in the protein anchored to the cell wall
  • H. K. Honjo, K. Ohsumi, H. Shimoi, H. Nakajima, and K. Kitamoto
  • J. Gen. Appl. Microbiol., 46, 113-117 (2000)
  • Molecular cloning and characterization of a gene encoding glutaminase from Aspergillus oryzae
  • K. Koibuchi, H. Nagasaki, A. Yuasa, J. Kataoka, K. Kitamoto
  • Appl. Microbiol. Biotechnol., 54, 59-68 (2000)
  • Purification and characterization of isoamyl acetate hydrolyzing esterase encoded by the IAH1 gene of Saccharomyces cerevisiae from a recombinant Escherichia coli
  • K. Fukuda, Y. Kiyokawa, T. Yanagiuchi, Y. Wakai, K. Kitamoto, Y. Inoue, and A. Kimura
  • Appl. Microbiol. Biotechnol., 53, 596-600 (2000)
  • Genetical analysis on growth inhibition of yeast cells caused by exprssion of A. oryzae RNase T1
  • G. Nonaka, T. Ishikawa, T. Liu, H. Nakajima, and K. Kitamoto
  • Biosci. Biotech. Biochem., 64, 2152-2158 (2000)
  • Production and product quality assessment of human hepatitis B virus Pre-s2 antigen in submerged and solid-state culture conditions of Aspergillus oryzae
  • J. Maruyama, H. Ohnuma, A. Yoshikawa, H. Kadokura, H. Nakajima, K. Kitamoto
  • J. Biosci. Bioeng., 90, 118-120 (2000)
1999年
  • Cloning and characterization of a gene (arpA) from Aspergillus oryzae encoding an actin-related protein required for normal nuclear distribution and morphology of conidiophores
  • K. Hirozumi, H. Nakajima, M. Machida, M. Yamaguchi, K. Takeo, and K. Kitamoto
  • Mol. Gen. Genet., 262, 758-767 (1999)
  • The protease activity of a calpain-like cysteine protease in Saccharomyces cerevisiae is required for alkaline adaptation and sporulation
  • E. Futai, T. Maeda, H. Sorimachi, K. Kitamoto, S. Ishiura, K. Suzuki
  • Mol. Gen. Genet., 260, 559-568 (1999)
  • Insertion analysis of putative functional elements in the promoter region of the Aspergillus oryzae Taka-amylase A gene (amyB) using a heterologous Aspergillus nidulans amdS-lacZ fusion gene system
  • Y. Kanemori, K. Gomi, K. Kitamoto, C. Kumagai, and G. Tamura
  • Biosci. Biotech. Biochem., 63, 180-183 (1999)
  • Aspergillus oryzae palBory encodes a clapain-like protease: homology to Emericella nidulans PalB and conservation of functional regions
  • E. Futai, H. Sorimachi, S. Y. Jeong, K. Kitamoto, S. Ishiura, and K. Suzuki
  • J. Biosci. Bioeng., 88, 438-440 (1999)
  • Cloning and characterization of the bipA gene encoding ER chaperone Bip from Aspergillus oryzae
  • T. Kasuya, H. Nakajima, K. Kitamoto
  • J. Biosci. Bioeng., 88, 472-478 (1999)
  • Characterization of a novel fungal protein, p15, which induces neuronal differentiation of PC12 cells
  • S. Wakatsuki, M. Arioka, N. Dohmae, K. Takio, M. Yamasaki, K. Kitamoto
  • J. Biochem., 126, 1151-1160 (1999)
1998年
  • Multidrug resistance phenotype conferred by overexpressing bfr2+ /pad1+/sks1+ or pap1+ genes and mediated by bfr1+ gene product, a structural and functional homologue of P-glycoprotein in Schizosaccharomyces pombe
  • M. Arioka, M. Kouhashi, K. Yoda, A. Takatsuki, M. Yamasaki, and K. Kitamoto
  • Biosci. Biotech. Biochem., 62, 390-392 (1998)
  • A novel screening method for microorganisms that efficiently remove heavy metals from aqueous solution
  • H. K. Honjo, S. Hata, K. Ohsumi, and K. Kitamoto
  • Biotechnology Techniques, 12, 91-95 (1998)
  • Brewing properties of sake yeast whose EST2 gene encoding isoamyl acetate-hydrolyzing esterase was disrupted
  • K. Fukuda, N. Yamamoto, Y. Kiyokawa, T. Yanagiuchi, Y. Wakai, K. Kitamoto, Y. Inoue, and A. Kimura
  • J. Ferment. Bioeng., 85, 101-106 (1998)
  • Identification and characterization of porcine NP-190, a novel protein that is specifically ezpressed in the axonal membrane during the embryonic period
  • S. C. Ho, S. Wakatsuki, M. Arioka, M. Yamasaki, and K. Kitamoto
  • J. Biochem., 123, 332-338 (1998)
  • Balance of activities of alcohol acetyltransferase and esterase in Saccharomyces cerevisiae is important for production of isoamyl acetate
  • K. Fukuda, N. Yamamoto, Y. Kiyokawa, T. Yanagiuchi, Y. Wakai, K. Kitamoto, Y. Inoue, and A. Kimura
  • Appl. Environ. Microbiol., 64, 4076-4078 (1998)
  • S19159, a modulator of neurite outgrowth produced by the ascomycete Preussia aemulans. I. Producing strain, fermentation, isolation and biological activity
  • T. Sato, T. Hanada, M. Arioka, K. Ando, J. Sugiyama, M. Uramoto, M. Yamasaki and K. Kitamoto
  • J. Antibiotics, 51, 897-901 (1998)
  • S19159, a modulator of neurite outgrowth produced by the ascomycete Preussia aemulans. II. Structure elucidation
  • T. Sato, T. Hanada, M. Arioka, T. Morita, H. Koshino, M. Uramoto, M. Yamasaki and K. Kitamoto
  • J. Antibiotics, 51, 1047-1050 (1998)
  • A plasmid pRH45 of Lactobacillus brevis confers a hop resistance
  • M. Sami, K. Suzuki, K. Sakamoto, H. Kadokura, K. Kitamoto, and K. Yoda
  • J. Gen. Appl. Microbiol., 44, 361-363 (1998)
  • Improvement of promoter activity by the introduction of multiple copies of the conserved region III sequence, involved in the efficient expression of Aspergillus oryzae amylase-encoding genes
  • T. Minetoki, C. Kumagai, K. Gomi, K. Kitamoto, and K. Takahashi
  • Appl. Microbiol. Biotechnol., 50, 459-67 (1998)
1997年
  • Isolation and characterization of nickel-accumulating yeasts
  • H. K. Honjo, A. Sugawara, K. Yoda, K. Kitamoto, and M. Yamasaki
  • Appl. Microbiol. Biotechnol., 48, 373-378 (1997)
  • Hop resistance Lactobacillus brevis contains a novel plasmid harboring a multidrug resistance-like gene
  • M. Sami, H. Yamashita, T. Hirono, H. Kadokura, K. Kitamoto, K. Yoda , and M. Yamasaki
  • J. Ferment. Bioeng., 84, 1-6 (1997)
  • A new and rapid method for determination of beer-spoilage ability of Lactobacilli
  • M. Sami, H. Yamashita, H. Kadokura, K. Kitamoto, K. Yoda and M. Yamasaki
  • J. Am. Soc. Brew. Chem., 55, 137-140 (1997)
  • Isolation and characterization of a 230 kDa protein (p230) which is specifically expressed in fetal brains:Its involvement in neurite outgrowth from rat cerebral cortex neurons grown on monolayers of astrocytes
  • S. Wakatsuki, S. C. Ho, M. Arioka, M. Yamasaki, and K. Kitamoto
  • J. Biochem., 122, 1146-1152 (1997)
1996年
  • Purification and characterization of a 15 kDa protein (p15) produced by Helicosporium which exhibits distinct effects on neurite outgrowth from cortical neurons and PC12 cells
  • T. Hanada, T. Sato, M. Arioka, M. Uramoto, and M. Yamasaki
  • Biochem. Biophys. Res. Comm. 228(1), 209-215 (1996)
  • Breeding of a new type of baker's yeast by d-integration for overproduction of glucoamylase using a homothallic yeast
  • S. Saito, Y. Mieno, T. Nagashima, C. Kumagai, and K. Kitamoto
  • J. Ferment. Bioeng., 81, 98-103 (1996)
  • Molecular cloning and nucleotide sequence of the isoamyl acetate-hydrolyzing esterase gene (EST2) from Saccharomyces cerevisiae
  • K. Fukuda, O. Kuwahata, Y. Kiyokawa, T. Yanagiuchi, Y. Wakai, K. Kitamoto, Y. Inoue, and A. Kimura
  • J. Ferment. Bioeng., 82, 8-15 (1996)
  • Deletion analysis of promoter elements of the Aspergillus oryzae agdA gene encoding a-glucosidase
  • T. Minetoki, Y. Nunokawa, K. Gomi, K. Kitamoto, C. Kumagai, and G. Tamura
  • Curr. Genet., 30, 432-438 (1996)
  • Cloning, characterization and overexpression of a gene (pdiA) encoding protein disulfide isomerase of Aspergillus oryzae
  • B. R. Lee, O. Yamada, K. Kitamoto, and K. Takahashi
  • J. Ferment. Bioeng., 82, 538-543 (1996)
  • Property of Taka-amylase A with Glu or Asp of the catalytic residue replaced by the corresponding amine
  • T. Oyama, M. Myojin, Y. Nitta, H. Toda, T. Nagashima, and K. Kitamoto
  • Biosci. Biotech. Biochem., 60, 1351-1352 (1996)