Publications

Original papers

  1. The Tetrafluoroethylene-Mediated Ring-Closing Metathesis: Enabling Unfavored Reactions
    Akiyama, M.*; Amabe, Y.; Sugiyama, M.; Sugiyama, K.; Gatzenmeier, T.; Okazoe, T.
    J. Am. Chem. Soc., in press.

  2. Exceptionally Short Tetracoordinated Carbon–Halogen Bonds in Hexafluorodihalocubanes
    Sugiyama, M.; Uetake, Y.*; Miyagi, N.; Yoshida, M.; Nozaki, K.; Okazoe, T.; Akiyama, M.*
    J. Am. Chem. Soc., 2024, 146, 30686–30697.

    Highlighted in ChemistryViews.

  3. Highly Alternating Copolymer of [1.1.1]Propellane and Perfluoro Vinyl Ether: Forming a Hydrophobic and Oleophobic Surface with <50% Fluorine Monomer Content
    Okuda. M.; Akiyama, M.*; Funahashi, K.; Masuda, J.; Kohata, A.; Nakagawa, S.; Kashiwagi, K.; Sugiyama, N.; Okazoe, T.; Kawaguchi, D.*
    ACS Macro Lett. 2024, 13, 1383–1389.

    Selected as ACS Editor's Choice.

  4. Pd-Catalyzed Thiotritylation Cross-Coupling of Aryl Bromides and Iodides to Access Sulfur Functional Groups
    Liu, Y.; Okazoe, T.; Gatzenmeier, T.; Nozaki, K.
    ChemistryEurope 2024, e202400053.


  5. Fluoro-Crown Ether Phosphate as Efficient Cell-Permeable Drug Carrier by Disrupting Hydration Layer
    Goswami, A*; Kohata, A.; Okazoe, T.; Huang, H.; Aida, T.*
    J. Am. Chem. Soc. 2024, 146, 23406–23411.


  6. Fluorocarbon–DNA conjugates for enhanced cellular delivery: Formation of a densely packed DNA nano-assembly
    Narita. M.; Kohata, A.*; Kageyama, T.; Watanabe, H.; Aikawa, K.*; Kawaguchi, D.; Morihiro, K.; Okamoto, A.; Okazoe, T.
    ChemBioChem 2024, e202400436.


  7. Copper-catalyzed Aminoazidation of Alkenes with NFC: One-step Vicinal Functionalization for CuAAC and SuFEx Reactions
    Kimura, H.; Aikawa, K.*; Hashimoto, T.*
    Asian J. Org. Chem. 2023, e202300522.


  8. Cellular Penetration and Intracellular Dynamics of Perfluorocarbon-Conjugated DNA/RNA as a Potential Means of Conditional Nucleic Acid Delivery
    Takatsu, M.; Morihiro, K.; Watanabe, H.; Yuki, M.; Hattori, T.; Noi, K.; Aikawa, K.*; Noguchi, K.; Yohda, M.; Okazoe, T.; Okamoto, A.*
    ACS Chem. Biol 2023, 18, 2590–2598.


  9. Fluoroalkylated Hypervalent Sulfur Fluorides: Radical Addition of Arylchlorotetrafluoro-λ6-sulfanes to Tetrafluoroethylene
    Yasuo, E.; Aikawa, K.*; Nozaki, K.; Okazoe, T.
    Chem. Sci. 2023, 14, 12379–12385.


  10. Difluorination of Heterobenzylic C–H Bonds with N-Fluoro-N-(fluorosulfonyl)carbamate (NFC)
    Adachi, A.; Hashimoto, T.*; Aikawa, K.*; Nozaki, K.; Okazoe, T.
    Org. Chem. Front. 2023, 10, 5362–5368.

    Featured on the Back cover.


  11. Synthesis of Short Peptides with Perfluoroalkyl Side Chains and Evaluation of Their Cellular Uptake Efficiency
    Kadota, K.; Mikami, T.; Kohata, A.; Morimoto, J.; Sando, S.; Aikawa, K.*; Okazoe, T.
    ChemBioChem 2023, e202300374.

    Featured on the Front cover.

  12. N-Fluorobenzenesulfonimide (NFSI) analogs with deprotectable substituents: Synthesis of β-fluoroamines via catalytic aminofluorination of styrenes
    Ito, Y.; Adachi, A.; Aikawa, K.*; Nozaki, K.; Okazoe, T.
    Chem. Commun. 2023, 59, 9195–9198.

    Featured on the Front cover.

  13. Straightforward Pentafluorosulfanylation for Molecular Design
    Gatzenmeir, T.*; Liu, Y.; Akamatsu, M.; Okazoe, T.; Nozaki, K.*
    ChemRxiv (preprint) 2023.

  14. The Fluorocarbene Exploit: Enforcing Alternation in Ring-Opening Metathesis Polymerization
    Tashiro, K.; Akiyama, M.*; Kashiwagi, K.; Okazoe, T.
    J. Am. Chem. Soc. 2023, 145, 2941–2950.


  15. Electron in a cube: Synthesis and characterization of perfluorocubane as an electron acceptor
    Sugiyama, M.; Akiyama, M.*; Yonezawa, Y.; Komaguchi, K.; Higashi, M.; Nozaki, K.; Okazoe, T.
    Science 2022, 377, 756–759. (Press Release from AGC Inc., UTokyo)
    (Highlighted by Science perspective, C&EN, Marketscreener, tech+, Chemistry World, 文藝春秋 10月号 p.265, 日本経済新聞, 東大新聞, Chem-Station, Science pipeline, Synform, C&EN molecules of the year, and 化学 2月号)


  16. Synthesis of Crystalline CF3-Rich Perfluoropolyethers from Hexafluoropropylene Oxide and (Trifluoromethyl)trimethylsilane
    Koyama, M.; Akiyama, M.*; Kashiwagi, K.; Nozaki, K.; Okazoe, T.
    Macromol. Rapid Commun. 2022, 43, 2200038.


  17. An N-Fluorinated Imide for Practical Catalytic Imidations
    Oe, Y.; Yoshida, R.; Tanaka, A.; Adachi, A.; Ishibashi, Y.; Okazoe, T.; Aikawa, K.*; Hashimoto, T.*
    J. Am. Chem. Soc. 2022, 144, 2107–2113. (Highlighted by ChemistryViews)


  18. Highly Active Cross Metathesis of Tetrafluoroethylene with a Seven-membered NHC-Ruthenium Catalyst
    Mori, K.; Akiyama, M.*; Inada, K.; Imamura, Y.; Ishibashi, Y.; Takahira, Y.; Nozaki, K.*; Okazoe, T.
    J. Am. Chem. Soc. 2021, 143, 20980–20987. (Highlighted by SYNFACTS)


  19. Methyl to trifluoromethyl substitution as a strategy to increase the membrane permeability of short peptides
    Ono, T.; Aikawa, K.; Okazoe, T.; Morimoto, J.*; Sando, S.*
    Org. Biomol. Chem. 2021, 19, 9386–9389.

  20. Bench-Stable Electrophilic Fluorinating Reagents for Highly Selective Mono- and Difluorination of Silyl Enol Ethers
    Adachi, A.; Aikawa, K.*; Ishibashi, Y.; Nozaki, K.; Okazoe, T.
    Chem. Eur. J. 2021, 27, 11919–11925.


  21. Synthesis of Fluorinated Dialkyl Carbonates from Carbon Dioxide as a Carbonyl Source
    Sugiyama, M.; Akiyama, M.; Nishiyama, K.; Okazoe, T.; Nozaki, K.*
    ChemSusChem 2020, 13, 1775–1784.


  22. Cyanide Free One-pot Synthesis of Methacrylic Esters from Acetone
    Koyama, M.; Kawakami, T.; Okazoe, T.; Nozaki, K.*
    Chem. Eur. J. 2019, 25, 10913–10917.

Books

  1. Aikawa, K.; Okazoe, T. "Perfluoroalkyl-containing Compounds as a Tool for Drug Delivery Systems,",
    Perfluoroalkyl Substances: Synthesis, Applications, Challenges and Regulations Ed. Améduri, B. Royal Society of Chemistry, 2022.

Prizes

    ・2024.3　Masafumi Sugiyama, The 41st Inoue Research Award for Young Scientists
    ・2024.3　Masafumi Sugiyama, The University of Tokyo Dean's Award 2023 (Doctor)
    ・2024.3　Masafumi Sugiyama, Sigma-Aldrich Rising Star award
    ・2023.12　Eisuke Yasuo, The 12th Fluorine Chemistry Young Researchers’ Conference, poster award
    ・2023.10　Dr. Ai Kohata, The 46th Fluorine Conference of Japan, presentation award
    ・2023.9　Mizuki Okuda, 72nd Symposium on Macromolecules, poster award
    ・2023.9　Eisuke Yasuo, The 39th Symposium on Synthetic Organic Chemistry, poster award
    ・2023.3　Yue Liu, The 103rd CSJ Annual Meeting, CSJ student presentation award
    ・2023.3　Kaoru Tashiro, The University of Tokyo, Dean's Award
    ・2022.11　Eisuke Yasuo, The 83rd Symposium of SSOCJ Kanto Branch, presentation award
    ・2022.11　Masafumi Sugiyama, The 2nd Online Symposium on Physical Organic Chemistry for Young Chemists, TCI Outstanding Discussion Award
    ・2022.11　Dr. Ai Kohata, The 49th International Symposium on Nucleic Acid Chemistry/The 6th Annual Meeting of Japan Society of Nucleic Acids Chemistry, ISNAC Outstanding Poster Award in 2022
    ・2022.11　Yuki Ito, The 45th Fluorine Conference of Japan, poster award
    ・2022.11　Koji Kadota, The 45th Fluorine Conference of Japan, presentation award
    ・2022.10　Koji Kadota, The 59th Japanese Peptide Symposium, Excellent Poster Presentation Award
    ・2022.9　Kaoru Tashiro, The 68th Symposium on Organometallic Chemistry, poster award
    ・2022.9　Ai Kohata, The L'Oréal-UNESCO for women in science Japan fellowships 2022
    ・2022.8　Koji Kadota, The 54st Summer School of Peptide Chemistry, best presentation award
    ・2022.3　Minoru Koyama and Masafumi Sugiyama, The 102nd CSJ Annual Meeting, CSJ student presentation award
    ・2021.11　Dr. Midori Akiyama, The 44th Fluorine Conference of Japan, presentation award
    ・2021.9　Masafumi Sugiyama, 10th Fluorine Chemistry Young Researchers’ Conference, poster prize
    ・2021.9　Masafumi Sugiyama, The 31st Symposium on Physical Organic Chemistry, lectreship award for students
    ・2021.8　Masafumi Sugiyama, The 52st Summer School of Structural Organic Chemistry, best discussion award
    ・2020.12　Masafumi Sugiyama, The 47th 有機典型元素化学討論会　lectreship award for students (ChemCommun prize)
    ・2020.10　Akiya Adachi, The 10th CSJ Chemistry Festa, poster award
    ・2019.8　Masafumi Sugiyama, The 51st Summer School of Structural Organic Chemistry, poster prize by lecturer
    ・2017.7　Dr. Midori Akiyama, The L'Oréal-UNESCO for women in science Japan fellowships 2017

Presentations

  1. Aggregation States and Surface Functional Properties of Thin Films of Partially Fluorinated Polymers Containing High Degree of Alternating Sequences
    Daisuke Kawaguchi, Mizuki Okuda, Junki Masuda, Ai Kohata, Shintaro Nakagawa, Kosuke Funahashi, Kimiaki Kashiwagi, Norihide Sugiyama, Takashi Okazoe, Midori Akiyama
    The 73rd Symposium on Macromolecules, Ikarashi Campus, Nigata University 2024/09/25-27 3H08
  2. Synthesis and thin-film properties of poly(nonafluorobutylstyrene)s
    Akamatsu Misato, Aikawa Kohsuke, Takashi Okazoe, Daisuke Kawaguchi
    The 73rd Symposium on Macromolecules, Ikarashi Campus, Nigata University 2024/09/25-27 2Pf032
  3. Design of water and oil repellent surface using crystalline lamella of polyethylene
    Kaoru Tashiro, Takashi Okazoe, Daisuke Kawaguchi
    The 73rd Symposium on Macromolecules, Ikarashi Campus, Nigata University 2024/09/25-27 3L08
  4. Design of fluorinated polynorbornene based on structure-physical properties relationship
    Makoto Uno, Takashi Okazoe, Daisuke Kawaguchi
    The 73rd Symposium on Macromolecules, Ikarashi Campus, Nigata University 2024/09/25-27 3L09
  5. Nano-assembled structures and cellular delivery of fluorocarbon-DNA conjugates
    Minako Narita, Ai Kohata, Taiichi Kageyama, Honoka Watanabe, Kohsuke Aikawa, Daisuke Kawaguchi, Kunihiko Morihiro, Akimitsu Okamoto, Takashi Okazoe
    XXV International Round Table on Nucleosides, Nucleotides and Nucleic Acids, Tokyo University of Science, Tokyo 2024/09/03-06 2K10
  6. Synthesis and Thin Film Properties of Highly Fluorinated Polynorbornenes
    Makoto Uno, Daisuke Kawaguchi, Takashi Okazoe
    The 73rd SPSJ Annual Meeting, Sendai International Center, Miyagi 2024/06/05-07 2K11
  7. Aggregation States and Surface Wettability in Films of Copolymers Containing a Relatively High Content of Perfluorovinylether
    Daisuke Kawaguchi, Mizuki Okuda, Junki Masuda, Ai Kohata, Shintaro Nakagawa, Kimiaki Kashiwagi, Norihide Sugiyama, Takashi Okazoe, Midori Akiyama
    The 73rd SPSJ Annual Meeting, Sendai International Center, Miyagi 2024/06/05-07 2K10
  8. Synthesis of perfluorocycloalkyl compounds using fluorine gas and their property
    Toshiki Nakajima, Koji Kadota, Masafumi Sugiyama, Kohsuke Aikawa, Daisuke Kawaguchi, Takashi Okazoe
    The 104th CSJ Annual Meeting, Funabashi Campus, Nihon University, Chiba 2024/03/18-21 E1141-3am-03
  9. Aminofluorination of alkenes utilizing with N–F reagents under copper catalysis
    Akiya Adachi, Yuki Ito, Takuya Hashimoto, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 104th CSJ Annual Meeting, Funabashi Campus, Nihon University, Chiba 2024/03/18-21 E1141-3am-02
  10. SF5-Heterocycles synthesis using direct oxidative fluorination
    Misato Akamatsu, Yue Liu, Tim Gatzenmeier, Kyoko Nozaki, Takashi Okazoe
    The 12th Fluorine Chemistry Young Researchers’ Conference, AGC Co., Ltd. AGC Manufacturing Training Center, Kanagawa 2023/12/8 P-12 (poster)
  11. Radical Addition Reaction of Chlorotetrafluoro-λ6-sulfanyl Arenes to Fluoroolefins and Its Application
    Eisuke Yasuo, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 12th Fluorine Chemistry Young Researchers’ Conference, AGC Co., Ltd. AGC Manufacturing Training Center, Kanagawa 2023/12/8 P-24 (poster)
  12. Synthesis and Properties of Copolymers Composed of [1.1.1]Propellane and Fluoroalkenes
    Mizuki Okuda, Junki Masuda, Ai Kohata, Shintaro Nakagawa, Kimiaki Kashiwagi, Norihide Sugiyama, Takashi Okazoe, Daisuke Kawaguchi, Midori Akiyama
    The 6th G'L'owing Polymer Symposium in KANTO (GPS-K 2023), Online, 2023/11/25 A10 (Regular presentation)
  13. Difluorination of Heterobenzylic C–H Bonds using with Electrophilic Fluorinating Reagent
    Akiya Adachi, Takuya Hashimoto, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 85th Symposium of SSOCJ Kanto Branch, Igarashi Campus, Niigata University, Niigata 2023/11/25-26 A-14 (oral)
  14. Radical Addition Reaction of Chlorotetrafluoro-λ6-sulfanyl Arenes to Fluoroolefins
    Eisuke Yasuo, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 123rd Symposium on Organic Synthesis, International Conference Center of Waseda University, Tokyo 2023/11/7-8 O-18
  15. CELLULAR UPTAKE OF PEPTIDES WITH VARIOUS FLUORINE FUNCTIONAL GROUPS: EFFECTS OF ALKYL AND FLUOROALKYL GROUPS
    Koji Kadota, Ai Kohata, Kohsuke Aikawa, Jumpei Morimoto, Shinsuke Sando and Takashi Okazoe
    The 60th Japanese Peptide Symposium, Biwako Hall, Center for the Performing Arts, Shiga 2023/11/8-10 2P-029 (Poster)
  16. Synthesis and Properties of Hexafluorodihalocubanes, and their interaction with Lewis Base
    Masafumi Sugiyama, Midori Akiyama, Kyoko Nozaki, and Takashi Okazoe
    The 46th Fluorine Conference of Japan, Kansaiidai Sho Hall (Osaka) 2023/10/16-17 O-06 (Oral)
  17. Cellular Uptake of Fluorine-Containing Ligand-Appended DNA
    Ai Kohata, Minako Narita, Taiichi Kageyama, Honoka Watanabe, Kohsuke Aikawa, Kunihiko Morihiro, Akimitsu Okamoto, and Takashi Okazoe
    The 46th Fluorine Conference of Japan, Kansaiidai Sho Hall (Osaka) 2023/10/16-17 O-18 (Oral)
  18. Difference between alkyl (RH) and perfluoroalkyl (RF) groups on peptide cellular uptake
    Koji Kadota, Ai Kohata, Kohsuke Aikawa, Jumpei Morimoto, Shinsuke Sando and Takashi Okazoe
    The 46th Fluorine Conference of Japan, Kansaiidai Sho Hall (Osaka) 2023/10/16-17 P-35 (Poster）
  19. Synthesis and Properties of Novel Fluoropolymers by Copolymerization of [1.1.1]Propellane and Fluoroalkenes
    Mizuki Okuda, Junki Masuda, Ai Kohata, Shintaro Nakagawa, Kimiaki Kashiwagi, Norihide Sugiyama, Takashi Okazoe, Daisuke Kawaguchi, Midori Akiyama
    72nd Symposium on Macromolecules, Saiwai-cho Campus, Kagawa University 2023/9/26-28 1Pe007(poster)
  20. Synthesis of perfluorocycloalkanes by liquid-phase fluorination using fluorine gas
    Toshiki Nakajima, Koji Kadota, Kohsuke Aikawa, Daisuke Kawaguchi, Takashi Okazoe
    The 46th Fluorine Conference of Japan, Hirakata Perfoming & Visual Arts Center, Osaka 2023/10/16-17 P-36 (poster)
  21. Radical Addition Reaction of Chlorotetrafluoro-λ6-sulfanyl Arenes to Tetrafluoroethylene and Its Application
    Eisuke Yasuo, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 39th Seminar on Synthetic Organic Chemistry, Awaji Yumebutai International Conference Center, Hyogo 2023/9/20-22 P-72 (poster)
  22. The Fluorocarbene Exploit: Enforcing Alternation in Ring-Opening Metathesis Polymerization
    Kaoru Tashiro, Midori Akiyama, Kimiaki Kashiwagi, Takashi Okazoe
    ISOM-XXIV–24th International Symposium on Olefin Metathesis and Related Chemistry, Bergen, Norway, 2023/07/02-05, PO30 (Poster)
  23. Novel Pathways to Pentafluorosulfanylated Compounds via Thiolation and Oxidative Fluorination
    Yue Liu, Tim Gatzenmeier, Takashi Okazoe, Kyoko Nozaki
    The 103rd CSJ Annual Meeting, Noda Campus, Tokyo University of Science, Chiba 2023/3/22-25 K703-2pm-07
  24. Development of Alternating Copolymerization by Ring-Opening Metathesis Polymerization of Fluoroalkenes
    Kaoru Tashiro, Midori Akiyama, Kimiaki Kashiwagi, Takashi Okazoe
    The 103rd CSJ Annual Meeting, Noda Campus, Tokyo University of Science, Chiba 2023/3/22-25 K301-1pm-06
  25. Fluorine-Containing Nucleic Acids with the Enhanced Cell Permeability
    Ai Kohata, Arisa Kagami, Taiichi Kageyama, Honoka Watanabe, Kohsuke Aikawa, Kunihiro Morihiro, Akimitsu Okamoto, Takashi Okazoe
    The 103rd CSJ Annual Meeting, Noda Campus, Tokyo University of Science, Chiba 2023/3/22-25 P1-1pm-28 (Poster)
  26. Synthesis and characterization of perfluorocubane as an electron acceptor
    M. Sugiyama, M. Akiyama, Y. Yonezawa, M. Higashi, K. Komaguchi, K. Nozaki, T. Okazoe
    26th Winter Fluorine Conference, Florida, USA, 2023/1/8-13
  27. Polyfluoroalkylation of Chlorotetrafluoro-λ6-sulfanyl Arenes
    Eisuke Yasuo, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 83rd Symposium of SSOCJ Kanto Branch, Niitsu Station East Campus, The Niigata University of Pharmacy and Medical and Life Sciences, Niigata 2022/11/26-27 B21
  28. Fluorinated DNAs for enhancing the cell permeability
    Ai Kohata, Taiichi Kageyama, Honoka Watanabe, Kohsuke Aikawa, Kunihiro Morihiro, Akimitsu Okamoto, Takashi Okazoe
    The 49th International Symposium on Nucleic Acid Chemistry/The 6th Annual Meeting of Japan Society of Nucleic Acids Chemistry, Katsushika Campus, Tokyo University of Science, Tokyo 2022/11/02-04 1P-62 (poster)
  29. Effects of perfluoroalkyl groups on cell penetrating peptides (CPPs)
    Koji Kadota, Toshiki Mikami, Ai Kohata, Kohsuke Aikawa, Jumpei Morimoto, Shinsuke Sando, Takashi Okazoe
    The 45th Fluorine Conference of Japan, Kyoto Institute of Technology Center Hall, Kyoto 2022/11/01-02 O-23
  30. Development of New Fluoropolymers by Copolymerization of [1.1.1]Propellane and Fluoroalkenes
    Mizuki Okuda, Junki Masuda, Midori Akiyama, Ai Kohata, Shintaro Nakagawa, Kimiaki Kashiwagi, Tokuhide Sugiyama, Takashi Okazoe
    The 45th Fluorine Conference of Japan, Kyoto Institute of Technology Center Hall, Kyoto 2022/11/01-02 P-52 (poster)
  31. Fluorinated modifiers for enhancing the cell permeability of nucleic acids
    Ai Kohata, Taiichi Kageyama, Honoka Watanabe, Kohsuke Aikawa, Kunihiro Morihiro, Akimitsu Okamoto, Takashi Okazoe
    The 45th Fluorine Conference of Japan, Kyoto Institute of Technology Center Hall, Kyoto 2022/11/01-02 P-49 (poster)
  32. Catalytic aminofluorination of alkenes utilizing NFSI derivatives with deprotectable substituents
    Yuki Ito, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 45th Fluorine Conference of Japan, Kyoto Institute of Technology Center Hall, Kyoto 2022/11/01-02 P-24 (poster)
  33. Cell-penetrating peptides (CPPs) with highly-fluorinated alkyl groups
    Koji Kadota, Toshiki Mikami, Ai Kohata, Kohsuke Aikawa, Jumpei Morimoto, Shinsuke Sando, Takashi Okazoe
    The 59th Japanese Peptide Symposium, TOHKnet Hall Sendai, Miyagi 2022/10/26-28 2P-052 (poster)
  34. Catalytic aminofluorination of alkenes utilizing NFSI derivatives with deprotectable substituents
    Yuki Ito, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 38th Seminar on Synthetic Organic Chemistry, Active Resorts FUKUOKA YAHATA, Fukuoka 2022/9/28-30 P-61 (poster)
  35. Radical Addition of Chlorotetrafluoro-λ6-sulfanyl Arenes to Tetrafluoroethylene
    Eisuke Yasuo, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 38th Seminar on Synthetic Organic Chemistry, Active Resorts FUKUOKA YAHATA, Fukuoka 2022/9/28-30 P-43 (poster)
  36. Alternating Copolymerization via Ring-Opening Metathesis Polymerization using Fluorinated Norbornenes
    Kaoru Tashiro, Midori Akiyama, Kimiaki Kashiwagi, Takashi Okazoe
    The 68th Symposium on Organometallic Chemistry, Online 2022/09/06-08 PC-37 (poster)
  37. Synthesis of Cycloenedioxyether by Ring-Closing Metathesis using Tetrafluoroethylene
    Yuki Amabe, Midori Akiyama, Tim Gatzenmeier, Takashi Okazoe
    The 68th Symposium on Organometallic Chemistry, Online 2022/09/06-08 PB-21 (poster)
  38. Development of New Fluoropolymers by Copolymerization of [1.1.1]Propellane and Fluoroalkenes
    Mizuki Okuda, Junki Masuda, Midori Akiyama, Ai Kohata, Shintaro Nakagawa, Kimiaki Kashiwagi, Tokuhide Sugiyama, Takashi Okazoe
    The 71st Symposium on Macromolecules, Sapporo Campus, Hokkaido University, Hokkaido 2022/09/05-07 2Pe015 (poster)
  39. Synthesis of novel perfluoropolyethers using hexafluoropropylene oxide
    Minoru Koyama, Midori Akiyama, Kimiaki Kashiwagi, Kyoko Nozaki, Takashi Okazoe
    The 102th CSJ Annual Meeting, Online 2022/3/23-26 C202-1pm-01
  40. Ring-Opening Metathesis Polymerization (ROMP) of norbornenes containing sp2 C–F bonds
    Kaoru Tashiro, Midori Akiyama, Takashi Okazoe
    The 102th CSJ Annual Meeting, Online 2022/3/23-26 D202-4am-03
  41. Synthesis and Properties of Perfluorocubane
    Masafumi Sugiyama, Midori Akiyama, Yuki Yonezawa, Kyoko Nozaki, Takashi Okazoe
    The 102th CSJ Annual Meeting, Online 2022/3/23-26 K1-4am-03
  42. Catalytic aminofluorination of alkenes utilizing NFSI derivatives with deprotectable substituents
    Yuki Ito, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 102th CSJ Annual Meeting, Online 2022/3/23-26 K4-4am-10
  43. Synthesis of Novel Tetrafluoro-λ6-sulfanyl Compounds using Tetrafluoroethylene
    Eisuke Yasuo, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 102th CSJ Annual Meeting, Online 2022/3/23-26 K4-4am-11
  44. Development of Fluorination at Benzylic Position of N-heterocycles using Electrophilic Fluorinating Reagents
    Akiya Adachi, Kohsuke Aikawa, Takuya Hashimoto, Kyoko Nozaki, Takashi Okazoe
    The 102th CSJ Annual Meeting, Online 2022/3/23-26 K4-4am-12
  45. Development of Cell-Penetrating Peptides with a perfluoroalkyl group on the side chain
    Koji Kadota, Toshiki Mikami, Kohsuke Aikawa, Jumpei Morimoto, Shinsuke Sando, Takashi Okazoe
    The 44th Fluorine Conference of Japan, online, 2021/11/15-16 P-20 (poster)
  46. Highly Active Cross-Metathesis of Tetrafluoroethylene with a Seven-membered NHC-Ruthenium Catalyst
    Midori Akiyama, Kenta Mori, Ko Inada, Yutaka Imamura, Yuichiro Ishibashi, Yusuke Takahira, Kyoko Nozaki, Takashi Okazoe
    The 44th Fluorine Conference of Japan, online, 2021/11/15-16 O-15
  47. Development of catalytic aminofluorination using NFSI derivatives with nosyl group
    Yuki Ito, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 11th CSJ Chemistry Festa, Online 2021/10/19-21 P2-030 (Poster)
  48. Synthesis of Novel Tetrafluoro-λ6-sulfanyl Compounds using Tetrafluoroethylene
    Eisuke Yasuo, Kohsuke Aikawa, Kyoko Nozaki, Takashi Okazoe
    The 11th CSJ Chemistry Festa, Online 2021/10/19-21 P5-049 (Poster)
  49. Synthesis of Perfluorocubane: Direct Fluorination of Highly Strained Molecules with Fluorine Gas
    Masafumi Sugiyama, Midori Akiyama, Yuki Yonezawa, Kyoko Nozaki, Takashi Okazoe
    10th Fluorine Chemistry Young Researchers’ Conference　Online, 2021/09/24 Students' presentation-3 (Oral) P16(Poster)
  50. Synthesis and Properties of Perfluorocubane Generated by Liquid-Phase Direct Fluorination with Fluorine Gas
    Masafumi Sugiyama, Midori Akiyama, Yuki Yonezawa, Kyoko Nozaki, Takashi Okazoe
    The 31st Symposium on Physical Organic Chemistry　Online, 2021/09/21-23 1B01(Oral)
  51. Synthesis and Properties of Perfluorocubane Generated by Liquid-Phase Direct Fluorination with Fluorine Gas
    Masafumi Sugiyama, Midori Akiyama, Yuki Yonezawa, Kyoko Nozaki, Takashi Okazoe
    The 31st Symposium on Physical Organic Chemistry　Online, 2021/09/21-23 1B01(Oral)
  52. Development of Selective Mono- and Difluorination of Silyl Enol Ethers using Novel Electrophilic Fluorinating Reagents
    Akiya Adachi, Kohsuke Aikawa, Yuichiro Ishibashi, Kyoko Nozaki, Takashi Okazoe
    The 101th CSJ Annual Meeting, Online 2021/3/19-22 A11-1pm-03
  53. Synthesis of fluorine containing oligonucleotides for cell membrane permeability and their assay
    Honoka Watanabe, Kohsuke Aikawa, Kunihiko Morihiro, Akimitsu Okamoto, Takashi Okazoe
    The 101th CSJ Annual Meeting, Online 2021/3/19-22 A25-2am-09
  54. New Approaches to Pentafluorosulfanylation
    Tim Gatzenmeier, Kyoko Nozaki, Takashi Okazoe
    The 100th CSJ Annual Meeting, Online 2021/3/19-22 A10-3am-02
  55. Highly Active Cross-Metathesis of Tetrafluoroethylene with a Seven-membered NHC-Ruthenium Catalyst
    Midori Akiyama, Kenta Mori, Ko Inada, Yutaka Imamura, Yuichiro Ishibashi, Yusuke Takahira, Kyoko Nozaki, Takashi Okazoe
    The 100th CSJ Annual Meeting, Online 2021/3/19-22 A15-3pm-03
  56. Development of Cell-Penetrating Peptides with a perfluoroalkyl group on the side chain
    Koji Kadota, Toshiki Mikami, Kohsuke Aikawa, Jumpei Morimoto, Shinsuke Sando, Kyoko Nozaki, Takashi Okazoe
    The 100th CSJ Annual Meeting, Online 2021/3/19-22 A04-4pm-05
  57. Synthesis of Perfluorocubane
    Masafumi Sugiyama, Midori Akiyama, Kyoko Nozaki, Takashi Okazoe
    The 47th 有機典型元素化学討論会　Online, 2020/12/3-5 O-37
  58. Synthesis of Novel Electrophilic Fluorinating Reagents Prepared from Fluorine Gas and Its Application to Fluorination Reactions
    Akiya Adachi, Kohsuke Aikawa, Yuichiro Ishibashi, Takashi Okazoe, Kyoko Nozaki
    The 10th CSJ Chemistry Festa, Online, 2020/10/20-22 P6-040 (Poster)
  59. ペルフルオロアルキル基を有する含フッ素細胞膜透過性ペプチドの開発
    Toshiki Mikami, Koji Kadota, Kohsuke Aikawa, Jumpei Morimoto, Shinsuke Sando, Kyoko Nozaki, Takashi Okazoe
    The 10th CSJ Chemistry Festa, Online, 2020/10/20-22 P6-040 (Poster)
  60. DEVELOPMENT OF PERFLUOROALKYL-CONTAINING CELL-PENETRATING PEPTIDE
    Toshiki Mikami, Kohsuke Aikawa, Jumpei Morimoto, Shinsuke Sando, Kyoko Nozaki, Takashi Okazoe
    The 100th CSJ Annual Meeting, Noda Campus, Tokyo University of Science, Chiba, Japan 2020/03/22-25 1G1-09
  61. Synthesis of Novel Electrophilic Fluorinating Reagents Prepared from Fluorine Gas and Its Application to Fluorination Reactions
    Akiya Adachi, Kohsuke Aikawa, Yuichiro Ishibashi, Takashi Okazoe, Kyoko Nozaki
    The 100th CSJ Annual Meeting, Noda Campus, Tokyo University of Science, Chiba, Japan 2020/03/22-25 3G3-14
  62. Synthesis of novel fluorine-containing amino acids and their application to cell penetrating peptides
    Toshiki Mikami, Kohsuke Aikawa, Jumpei Morimoto, Shinsuke Sando, Kyoko Nozaki, Takashi Okazoe
    The 42nd Fluorine Conference of Japan, Kobe University, Rokko-dai 2nd campus, Hyogo, Japan 2019/11/21-22 (Poster)
  63. Development of electrophilic fluorination reagents prepared by fluorine gas
    Akiya Adachi, Kohsuke Aikawa, Yuichiro Ishibashi, Takashi Okazoe, Kyoko Nozaki
    The 116th Symposium on Synthetic Organic Chemistry 2019【autumn】
    Waseda University International Conferenece Center, Tokyo, Japan 2019/10/31-11/01 P-10(Poster)
  64. Fluorine-containing oligonucleotides for cell membrane permeability
    Honoka Watanabe, Kohsuke Aikawa, Kunihiko Morihiro, Akimitsu Okamoto, Yuichiro Ishibashi, Takashi Okazoe
    The 46th International Symposium on Nucleic Acids Chemistry/The 3rd Annual Meeting of Japan Society of Nucleic Acids Chemistry
    Koganei Civic Center (Miyaji Gakki hall), Tokyo, Japan 2019/10/29-31 (Poster)
  65. DEVELOPMENT OF FLUORINE-CONTAINING CELL-PENETRATING PEPTIDE
    Toshiki Mikami, Kosuke Aikawa, Jumpei Morimoto, Shinsuke Sando, Kyoko Nozaki, Takashi Okazoe
    The 56th Japanese Peptide Symposium, Tokyo Medical and Dental University, Akio Suzuki Memorial Hall, Tokyo, Japan 2019/10/23-25 (Poster)
  66. Synthesis of Polyfluorocubane
    Masafumi Sugiyama, Midori Akiyama, Kyoko Nozaki, Takashi Okazoe
    The 30th Symposium on Physical Organic Chemistry　Osaka International House Fondation, Osaka, Japan 2019/09/25-27 2P092(Poster)
  67. Synthesis of Fluorinated Dialkyl Carbonates from CO2
    Midori Akiyama, Masafumi Sugiyama, Kohei Nishiyama, Kyoko Nozaki, Takashi Okazoe
    19TH EUROPEAN SYMPOSIUM ON FLUORINE CHEMISTRY, Walsaw, Poland, 2019/8/25-31
  68. One-pot synthesis of methacrylic acid ester from acetone, chloroform, and alcohol
    Minoru Koyama, Takafumi Kawakami, Takashi Okazoe, Kyoko Nozaki
    8th JACI / GSC Symposium 2019 Tokyo International Forum, Tokyo, Japan 2019/06/24-25 C-29(Poster)
  69. Synthesis of Fluorinated Dialkyl Carbonates by CO2 fixation
    Masafumi Sugiyama, Midori Akiyama, Kohei Nishiyama, Kyoko Nozaki, Takashi Okazoe
    8th JACI / GSC Symposium 2019 Tokyo International Forum, Tokyo, Japan 2019/06/24-25 C-80(Poster)
  70. One-pot synthesis of methacrylic esters from acetone, chloroform and alcohols
    Minoru Koyama, Takafumi Kawakami, Takashi Okazoe, Kyoko Nozaki
    23rd Annual Green Chemistry & Engineering Conference/9th International Conference on Green & Sustainable Chemistry, Hyatt Regency Reston, Reston, Virginia, USA, 2019/6/11-13 (Poster)
  71. Investigation of the Ligand Effect on Cross Metathesis with Tetrafluoroethylene by Ruthenium Catalyst
    Kenta Mori, Midori Akiyama, Yusuke Takahira, Nobuyuki Otozawa, Takashi Okazoe, Kyoko Nozaki
    The 99th CSJ Annual Meeting, Okamoto Campus, Konan University, Kobe, Japan 2019/03/16-19 2D1-47
  72. Synthesis of Fluorinated Dialkyl Carbonates from Carbon Dioxide as Carbon Source
    Masafumi Sugiyama, Midori Akiyama, Kohei Nishiyama, Kyoko Nozaki, Takashi Okazoe
    The 99th CSJ Annual Meeting, Okamoto Campus, Konan University, Kobe, Japan 2019/03/16-19 1F2-12
  73. Synthesis of Fluorinated Dialkyl Carbonates from Carbon Dioxide
    Midori Akiyama, Masafumi Sugiyama, Kohei Nishiyama, Kyoko Nozaki, Takashi Okazoe
    The 41th Fluorine Conference of Japan, Hirosaki, Aomori, Japan 2018/10/25-26 O-25
  74. Non-Phosgene Method for Synthesis of Fluorinated Dialkyl Carbonates from Inorganic Carbonates
    Masafumi Sugiyama, Midori Akiyama, Kyoko Nozaki, Takashi Okazoe
    The 41th Fluorine Conference of Japan, Hirosaki, Aomori, Japan 2018/10/25-26 P-38(poster)