Laboratory of Molecular Design and Molecular Evolution
Molecular Design for Understanding Life Phenomena and Advancing Disease Treatment
1. Disease Metabolic Imaging
We aim to identify disease biomarkers and realize metabolic imaging of biological systems to elucidate disease mechanisms and facilitate early diagnosis.
・In Vivo Molecular ChemistryWe develop molecular probes for disease metabolic imaging based on original designs grounded in organic chemistry.
2. Design of functional middle-sized molecules
We are pioneering synthetic methodologies for medium-sized molecules, building high-throughput screening platforms, and leveraging data science to design molecules with novel functions.
・Artificial Peptide Drug DiscoveryWe are advancing research on peptides and peptidomimetics based on our original molecular design technologies, aiming to develop tools for biomolecular manipulation and innovative peptide-based therapeutics. We also aim to realize functional peptides through our original DNA-encoded peptide libraries and data science approaches.
・Chemical biology of fatty acids and lipidsEnglish ver. coming soon.