2022
Takahashi, K., Jia, H., Takahashi, S. and Kato, H. Comprehensive miRNA and DNA microarray analysis reveal the response of
hepatic miR-203 and its target gene to protein malnutrition in rats. Genes, 13, 75 (2022)
Miyoshi, M., Saito, K., Jia, H. and Kato, H. Maternal protein restriction and post-weaning high-fat feeding alter plasma amino acid profiles and hepatic gene expression in mice offspring. Foods, 11, 753 (2022)
Yang, Y., Jia, H., Furukawa, K., Li, X., Hasebe, Y. and Kato, H. Dietary eggshell membrane powder improves survival rate and ameliorates
gut dysbiosis in interleukin-10 knockout mice. Front. Nutr. 9, 895665 (2022)
Takahashi, S., Saito, K., Li, X., Jia, H. and Kato, H. iTRAQ-based quantitative proteomics reveals the energy metabolism alterations
induced by chlorogenic acid in HepG2 cells. Nutrients, 14, 1676 (2022)
Jia,H., Yamashita,T. ,Li,X. and Kato, H. Laurel attenuates dexamethasone-induced skeletal muscle atrophy in vitro
and in a rat model.Nutrients,14, 2029 (2022)
Jia,H., Lyu,W,Hirota,K., Saito,E., Miyoshi,M., Hohjoh,H., Furukawa,K., Saito,K., Haritani,M., Taguchi,A., Hasebe,Y. and Kato, H.Eggshell membrane modulatesgut microbiota to prevent murine pre-cachexia
through suppression of T helper celldifferentiation.J. Cachexia Sarcopenia Muscle,13, 2088-2102(2022)
Watanabe, K., Hirayama, M., Arumgam, S., Sugawara, M., Kato, H., Nakamura,
S., Ohtsubo, K., Matsumoto, H., Nomi, Y., Homma, N., Fujii,Y., Murohashi,
N., Thandavarayan, A., Suzuki, H., Fujihara, K., Kodama,S. and Sone, H.
Effect of heat-moisture treated brown rice crackers on postprandial flow-mediated
dilation in adults with mild endothelial dysfunction.
Heliyon, 8, e10284 (2022)
Miyoshi, M., Imakado, Y., Otani, L., Kaji, M., Aanzai, Y., Sugimoto, N.,
Murakami, T., Fukuoka, M., Hohjoh, H., Jia, H. and Kato, H. Maternal protein
restriction induces renal AT2R promoter hypomethylation in salt-sensitive,
hypertensive rats. Food Sci. Nutr.9, 1452-1459 (2021)
Yamamura, J., Ma, S., Jia, H. and Kato, H. ATF4-dependent hsa-miR-663a transcription
mediates mTORC1/p70S6K1 signaling under leucine deprivation. Front. Nutr. 9, 965771 (2022)
Igarashi,
M., Nogawa, S., Hachiya, T., Furukawa, K., Takahashi, S., Jia, H., Saito,
K. and Kato,
H. Association between dietary behaviors and BMI stratified by sex and the
ALDH2 rs671 polymorphism in Japanese adults. Nutrients, 14, 5116
(2022)
Furukawa, K.,
Kousaka, M., Jia, H. and Kato, H. Suppressive effects of turmeric
extract on muscle atrophy in dexamethasone-treated mice and myotubes. Nutrients, 14, 3929 (2022)
Ma, S., Hasegawa, E., Nakai, Y., Jia, H. and Kato,
H. Transcriptome and methylome profiling in rat skeletal muscle: Impact of
post-weaning protein restriction. Int. J.
Mol. Sci. 23, 15771 (2022)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Ando, C., Ma, S., Miyoshi, M., Furukawa, K., Li, X., Jia, H. and
Kato, H. Postnatal nutrition environment reprograms renal DNA methylation
patterns in offspring of maternal protein-restricted stroke-prone spontaneously
hypertensive rats. Front. Nutr. 10, in press (2023)
著書・総説
Warman, D.J., Jia, H. and Kato, H. The potential roles of probiotics, resistant starch, and resistant proteins
in ameliorating inflammation during aging (inflammaging). Nutrients, 14, 747 (2022)
加藤久典、プレシジョン栄養の幕開け、実験医学(増刊)、40, 1202-1205 (2022)
Livingstone, K.M., Ramos-Lopez, O., Perusse, L., Kato, H. Ordovas, J.M., Martinez, J.A. Precision nutrition: A review of current
approaches and future endeavors. Trends Food Sci. Technol. 128, 253-264 (2022)
加藤久典、妊娠中のタンパク質栄養と子の高血圧および食塩感受性、食と医療、24,30-35(2023)
加藤久典(監修)「文系のための東大の先生が教える食と栄養」ニュートンプレス、(2023)
Takahashi, K., Jia, H., Takahashi, H. and Kato H. Comprehensive miRNA and DNA microarray analysis reveal the response of
hepatic miR-203 and its target gene to protein malnutrition in rats. Genes, in press
Jia, H. Wen, Y.,
Aw, W., Saito, Y. and Kato, H. Ameliorating effects of coriander on gastrocnemius muscles undergoing
precachexia in a rat model of rheumatoid arthritis: A proteomics analysis.Nutrients, 13, 4041 (2021)
Saito, K., Ito,
M., Chiba, T., Jia, H. and Kato, H. A comparison of gene expression profiles of rat tissues after mild and
short-term calorie restrictions. Nutrients,
13, 2277 (2021)
Furukawa, K.,
Kono M., Kataoka, T., Hasebe, Y., Jia, H. and Kato, H. Effects of eggshell
membrane on keratinocyte differentiation and skin aging in vitro and in vivo. Nutrients, 13, 2144 (2021)
Yang, Y., Fukui, R., Jia, H. and Kato, H. Amaranth supplementation ameliorates high-fat diet-induced dyslipidemia
and deterioration of gut microbiota structure in mice. Foods, 10, 1259 (2021)
Lyu, W., Jia, H., Deng, C., Yamada, S. and Kato, H. Zeolite-containing mixture alleviates microbial dysbiosis in dextran
sodium sulfate induced colitis in mice. Food Sci. Nutr. 9, 772-780 (2021)
Miyoshi, M., Imakado, Y., Otani, L., Kaji, M., Aanzai, Y., Sugimoto, N.,
Murakami, T., Fukuoka, M., Hohjoh, H., Jia, H. and Kato, H. Maternal protein restriction induces renal AT2R promoter hypomethylation
in salt-sensitive, hypertensive rats. Food Sci. Nutr.9, 1452-1459 (2021)
Aw, W., Jia, H., Lyu, W., Fukuda, S., Tomita, M., Otani, L. and Kato, H. Integrated omics profiling of dextran sodium sulfate-induced colitic mice supplemented with Wolfberry (Lycium barbarum) Sci.Food, 4, 5 (2020)
Toyoshima, Y., Yoshizawa, F., Tokita, R., Taguchi, Y., Takahashi, S.-I.,
Kato, H. and Minami, S. A translation repressor, 4E-BP1, regulates the
triglyceride level in rat liver during protein deprivation. Am. J. Physiol.
Endocrinol. Metab. 318 . E636-E945 (2020)
Ramli, N. S., Jia, H., Sekine, A., Lyu, W., Furukawa, K., Saito, K., Hasebe,
Y. and Kato, H. Eggshell membrane powder lowers plasma triglyceride and
liver total cholesterol by modulating gut microbiota and accelerating lipid
metabolism in high ‐fat diet‐fed mice. Food Sci.Nutr.8, 2512-2523 (2020)
Kawafune, K., Hachiya, T., Nogawa, S., Takahashi, S., Jia, H., Saito, K.
and Kato, H. Strong association between the 12q24 locus and sweet taste
preference in the Japanese population revealed by genome-wide meta-analysis.
J. Human, Genet. 65,939-947 (2020)
Toyoshima, Y.,
Nakamura, K., Tokita, R., Teramoto, N., Sugihara, H., Kato, H.,
Yamanouchi, K, and Minami, S. Disruption of insulin receptor substrate-2
impairs growth but not insulin function in rats. J.Biol. Chem.295,11914-11927 (2020)
Otani, L., Nishi,
H., Koyama, A., Akasaka, Y., Taguchi, Y., Toyoshima, Y., Yamanaka, D., Hakuno,
F., Jia, H., Takahashi, S.-I. and Kato, H. Low-arginine and low-protein diets induce hepatic lipid accumulation through
different mechanisms in growing rats. Nutr. Metab. 17,60 (2020)
Hamano, M., Tomonaga,
S., Osaki, Y., Oda, H., Kato, H. and Furuya, S. Transcriptional activation of Chac1 and other Atf4-target
genes induced by extracellular L-serine depletion is negated with glycine
consumption in Hepa1-6 hepatocarcinoma cells. Nutrients, 12,3018 (2020)
Furukawa, K.,
Igarashi, M., Jia, H., Nogawa, S., Kawafune, K., Hachiya, T., Takahashi, S.,
Saito, K. and Kato, H. A Genome-wide association study identifies the association between the
12q24 locus and black tea consumption in Japanese populations. Nutrients, 12, 3182 (2020)
Yagi,T.,Toyoshima,Y.,Tokita,R.,Taguchi,Y.,Okamoto,Y,Takahashi,SI,Kato,H.and Minami,S.Low-protain diet enhances adiponectin secretion in rats.Biosci.Biotechnol.Biochem.83,1774-1781(2019)
Igarashi,M.,Nogawa,S.,Kawafune,K.,Hachiya,T.,Takashima,S.,jia,H.,Saito,K
and Kato,H. Identification of the 12q24 locus associated with fish intake frequency by genome-wide meta-analysis in Japanese population.Gene Nutr.14,21(2019)
Jia,H.,Nogawa,S.,Kawafune,K.,Hachiya,T.,Takahashi,S.,Igarashi,M.,Saito,k.and Kato H. GWAS of habitual coffee consumption reveals a sex difference in the genetic
effect of the 12q24 locus in the Japanese population.BMC Genet.20,61(2019)
加藤久典、髙橋祥子 マルチオミクスとインターネットコホートによる食と栄養へのアプローチ、実験医学 37 536-541(2019)
加藤久典、加藤将夫(編著)「核酸の分子栄養学」エヌ・ティー・エス(2019)
Miyoshi,M.,Sato,M.,Saito,K.,Otani,L.,Shirahige,k.,Miura,F.,Ito,T.,jia,H.and
Kato,H.Meternal protein restriction alters the renal ptgerl DNA methylation
state in SHRSP offspring.Nutrients, 10,1436(2018)
Hamano, M., Haraguchi, Y., Sayano, T., Zyano, C., Arimoto, Y., Kawano,
Y., Moriyasu, K., Udono, M., Katakura, Y., Ogawa, T., Kato, H. and Furuya,
S. Enhanced vulnerability to oxidative stress and induction of inflammatory
gene
exprssion in 3-phosphoglycerate dehydrogenase-deficient fibroblasts. FEBS Open Bio, 8,914-922(2018)
Horiucti ,M., Takeda, T., Takanashi, H., Ozaki-Masuzawa, Y., Taguchi, Y.,Toypshima,
Y., Otani, L., Kato, H., Sone-Yonezawa, M.,Hakuno, F., Takahashi, S.-I.
and Takenaka, A. Branched-chain amino acid supplementation restores
reduced insulinotropic activity of a low-protein diet through the vagus
nerve in rats. Nutr.Metab. 14, 59 (2017)
Taguchi, Y., Tokita, R., Kato, H., Takahashi, S.-I., and Minami, S. Triglyceride synthesis in hepatocytes isolated from rats fed a low-protein diet is enhanced independently of upregulation of insulin signaling. Biochem. Biophys. Res. Commun. 490,800-805 (2017)
Lyu, W., Jia, H., Deng, C., Saito, K., Yamada, S. and Kato, H. Zeolite-containing
mixture supplementation ameliorated dextran sodium sulphate-induced colitis
in mice by suppressing the inflammatory bowel disease pathway and improving
apoptosis in colon mucosa. Nutrients 9, 467 (2017)
Jia, H., Hanate, M., Aw, W., Itoh, H., Saito, K., Kobayashi, S., Hachimura,
S., Fukuda, S., Tomita, M., Hasebe, Y. and Kato. H. Eggshell membrane powder
ameliorates intestinal inflammation by faciliating the restitution of epithelial
injury and alleviating microbial dybiosis. Sci. Rep. 7, 43993 (2017)
Sato, Y., Uchida, E., Aoki, H., Hanamura, T., Nagamine, K., Kato, H., Koizumi,
T. and Ishigami, A. Acerola (Malpighia emarginata DC.) juice intake suppresses
the UVB-induced skin pigmentation in SMP30/GNL knockout hairless mice PLoS One, 12,e0170438 (2017)
Takahashi, S., Jia, H., Saito, K. and Kato, H. Comparative integrated omics approach sterically understanding hepatic metabolic dynamics in mouse model. J. Integr. OMICS 7,200 (2017)
Nakamura, K., Morishita, S., Ono, T,. Murakoshi, M., Sugiyama, K., Kato,
H., Ikeda, I. and Nishino, H. Lactoferrin interacts with bile acids and
increases fecal cholesterol excretion in rats. Biochem. Cell Biol. 95,142-147 (2017)
Aoyama, S., Jia, H., Nakazawa, K., Yamamura, J., Saito, K. and Kato, H.
Dietary genistein prevents denervation-induced muscle atrophy in rodents
via effects on estrogen receptor-alpha J. Nutr.146, 1146-1154 (2016)
Otani, L,. Mori, T., Koyama, A,. Takahashi, S.-I., and Kato, H. Supplemental
arginine above the requirement during suckling causes obesity and insulin
resistance in rats. Nutr. Res. 36, 575-585 (2016)
Sayano, T., Kawano, Y., Kusada, W., Arimoto, Y., Esaki, K., Hamano, M.,
Udono, M., Katakura, Y., Ogawa, T., Kato, H., Hirabayashi, Y. and Furuya,
S. Adaptive response to L-serine deficiency is mediated by p38 MAPK activation
via deoxysphinganine in normal fibroblasts. FEBS Open Bio 6, 303-316 (2016)
Morishita, S., Kawaguchi H., Ono, T., Miura, N., Murakoshi, M., Sugiyama,
K., Kato, H., Tanimoto, A. and Nishino, H. Enteric lactoferrin attenuates
the development of high-fat and high-cholesterol diet-induced hypercholesterolemia
and atherosclerosis in Microminipigs. Biosci. Biotechnol. Biotechem.80,
295-393(2016)
Yoshimura, R, Takai, M., Namaki, H., Minami, K., Imamura, W., Kato, H.,
Kamei, Y. and Kanamoto R. Down regulation of asparagine synthetase and
3-phosphoglycerate dehydrogenase, and the up-regulation of serine dehydratase
in rat liver from intake of excess amount of leucine are not related to
leucine-caused amino acid imbalance. J. Nutr. Sci. Vitaminol. 61, 441-448
(2015)
Morishita, S., Tomita, K., Ono, T., Murakoshi, M., Saito, K., Sugiyama,
K., Nishino, H. and Kato, H. Lactoferrin attenuates fatty acid-induced
lipotoxicity via Akt signaling in hepatocarcinoma cells. Biochem. Cell
Biol.93, 566-573 (2015)
Ozaki, Y., Saito, K., Nakazawa, K,. Konishi, M., Itoh, N., Hakuno, H.,
Takahashi, S.-I., Kato, H. and Takenaka, A. Rapid increase of fibroblast
growth factor 21 under protein malnutrition and its impact on growth and
lipid metabolism. Brit. J. Nutr.114, 1410-1418 (2015)
Li, J., Inoue, J., Choi, J.-M., Nakamura, S., Yan, Z., Fushinobu, S., Kamada,
H., Kato, H., Hashidume, T., Shimizu, M. and Sato, R. Identification of
the flavonoid luteolin as a repressor of the transcription factor hepatocyte
nuclear factor 4a . J. Biol. Chem.290, 24021-24031 (2015)
Aw, W., Jia, H., Takahashi, S., Fukuda, S. and Kato, H. Chapter 3: The comprehensive understanding of anti-diabetic and anti-obesity effects of coffee intake via nutrigenomics. In: Caffeic acid: Biological properties, structure and health effects. Vaughn, L (ed) Nova Science Publishers, pp. pp. 47-62 (2015)
Jia, H., Aw, W., Saito, K., Hanate, M,m Hasebe, Y. and Kato, H. Eggshell membrane ameliorates hepatic fibrogenesis in human C3A cells
and rats through changes in PPARγ-Endothelin 1 signaling. Sci. Rep.4,7473(2014)
Jia,H., Aw, W., Hanate, M., Takahashi, S., Saito, K., Tanaka, H., Tomita,
M. and Kato, H. Multi-faceted integrated omics analysis revealed Parsley
(Petroselinum crispum) as a novel dietary intervention in dextran sodium
sulphate induced colitic mice. J. Funct. Food 11,438-448(2014)
Chang, W.-C., Jia, H., Aw, W. Saito, K., Hasegawa, S. and Kato, H. Beneficial
effects of soluble dietary Jerusalem artichoke (Helianthus tuberosus) in
the prevention of the onset of Type 2 diabetes and NAFLD in high fructose-fed
rats. Brit. J. Nutr.112, 719-717(2014)
Nekohashi, M., Ogawa, M., Ogihara, T., Nakazawa, K., Kato, H., Misaka,
T., Abe, K. and Kobayashi, S. Luteolin and quercetin affect the cholesterol
absorption mediated by epithelial cholesterol transporter Niemann–Pick
C1-like 1 in Caco-2 cells and rats. PLoS One. 9, e97901 (2014)
Fukushima, E., Monoi, N., Mikoshiba, S., Hirayama, Y., Serizawa, T., Adachi,
K., Koide, M., Ohdera, M., Murakoshi, M. and Kato, H. Protective effects
of acetaminophen on ibuprofen-induced gastric mucosal damage in rats with
associated suppression of matrix metalloproteinase. J. Pharmacol. Exp.
Ther.349,165-173 (2014)
Takahashi, S., Saito, K., Jia, H. and Kato, H. An integrated multi-omics
study revealed metabolic alterations underlying the effects of coffee consumption.
PLOS ONE, 9, e91134 (2014)
Toyoshima, Y., Tokita, R., Taguchi, Y., Akiyama-Akanishi, N., Takenaka,
A., Kato, H., Chida, K., Hakuno, F., Minami, S. and Takahashi, S.-I. Tissue-specific
effects of protein malnutrition on insulin signaling pathway and lipid
accumulation in growing rats. Endocr. J. 61,499-512 (2014)
Jia, H., Aw, W., Egashira, K., Takahashi, S., Aoyama, S., Saito, K., Kishimoto,
Y. and Kato, H. Coffee intake mitigated inflammation and obesity-induced
insulin resistance in skeletal muscle of high-fat diet-induced obese mice.
Genes Nutr.9,389 (2014)
Jia, H., Aw, W., Saito, K., Hanate, M,m Hasebe, Y. and Kato, H. Eggshell
membrane ameliorates hepatic fibrogenesis in human C3A cells and rats through
changes in PPARγ-Endothelin 1 signaling. Sci. Rep. 4, 7473 (2014)
Jia, H., Tamura, N., Aw, W., Doi, M. and Kato, H. Identification of branched
amino acids; Underlying molecular pathways using transcriptomics analysis:
Application to cirrhosis. In: Branched chain amino acids in clinical nutrition
vol. 2. Rajendram, R., Preedy, V.R. and Patel, V.B. (eds) Humana Press,
pp141-157 (2014)
小田裕昭、加藤久典、関泰一郎(編著)「健康栄養学-健康科学としての栄養生理化学- 第2版」共立出版(2014)
賈慧娟、花手愛夏、加藤久典、長谷部由紀夫 卵殻膜摂取による潰瘍性大腸炎の抑制効果Food Style 21, 18, 80-82 (2014)
加藤久典ニュートリゲノミクス 食品と栄養における網羅的解析、化学と工業、67, 122-124 (2014)
Srinivasan,V., Mohamed, M., and Kato, H. Melatonin: its microbicidal propertiesand
clinical applications. In: Melatonin and melatonergic drugs in clinical
practice. Srinivasan, V., Brzezinski, A., Oter, S. and Shillcutt, S.D.
(eds) Springer, 57-69, (2014)
加藤久典 ニュートリゲノミクスの広がりと統合ニュートリオミクス、New Diet Therapy, 29(4), 15-22 (2014)
加藤久典 第5章 タンパク質の構造と機能、第6章 酵素 「新スタンダード栄養・食物シリーズ 生化学」(大塚譲他編)東京化学同人 pp. 29-46 (2014)
加藤久典第2章6 アミノ酸摂取と遺伝子発現 「アミノ酸科学の最前線-基礎研究を活かした応用戦略―」(鳥居邦夫、門脇基二監修)シーエムシー出版 pp.94-99 (2014)
加藤久典、藤原葉子(編) 「栄養科学イラストレイテッド:分子栄養学~遺伝子の基礎からわかる」羊土社 (2014)
加藤久典 アミノ酸の機能や安全性の研究におけるオミクス 生化学, 86, 318-323 (2014)
Jia, H., Takahashi,S., Saito, K. and Kato, H. DNA microarray analysis identified
molecular pathways mediating the effect of the supplementation of branched
amino acids on CCl4-induced cirrhosis in rats. Mol. Nutr. Food Res. 57,
291-306 (2013)
Imamura, W., Yoshimura, R., Takai, M., Yamamura, J., Kanamoto, R. and Kato,
H. Adverse effects of excessive leucine intake depend on dietary protein
intake: A transcriptomic analysis to identify useful biomarkers. J. Nutr.Sci.
Vitaminol.59,45-55(2013)
Ono, T., Fujisaki, C., Ishihara, Y, Ikoma, K., Morishita, S., Murakoshi,
M., Sugiyama, K., Kato, H., Miyashita, K., Yoshida, K. and Nishino, H.
Potent lipolytic activity of lactoferrin in mature adipocytes. Biosci.
Biotechnol. Biochem.77, 566-571 (2013)
Jia, H., Saito, K., Aw, W., Takahashi, S., Hanate, M, and Kato, H. Transcriptional
profiling in rats and an ex vivo analysis implicate novel beneficial function
of egg shell membrane in liver fibrosis. J. Funct. Foods 5. 1611-1619 (2013)
Takahashi, S., Egashira, K., Jia, H., Saito, K., Abe, K. and Kato, H. Coffee
intake down-regulates the hepatic gene expression of peroxisome proliferator-activated
receptor gamma in C57BL/6J mice fed a high-fat diet. J. Funct. Foods, 6,
157-167 (2014)
加藤久典、青山晋也 高齢者の筋機能維持に向けた大豆成分の有効利用の基礎研究 大豆タンパク質研究、15, 85-89 (2013)
斉藤憲司、高橋祥子、加藤久典 第3章 ニュートリゲノミクスを加速するツールの開発 「ニュートリゲノミクスを基盤としたバイオマーカーの開発-未病診断とテーラーメード食品開発に向けて-」シーエムシー出版、PP39-44(2013)
大谷りら、村上哲男、加藤久典 タンパク質栄養に起因する生活習慣病発症機序 胎児期から新生児期に刻まれる栄養の記憶、化学と生物、51,785-788(2013)
Morishita, S., Ono, T., Fujisaki, C., Ishihara, Y., Murakoshi, M., Kato,
H., Hosokawa, M., Miyashita, K., Sugiyama, K. and Nishino, H. Bovine lactoferrin
reduces visceral fat and liver triglycerides in ICR mice. J. Oleo Sci.
62:97-103 (2012)
Jia, H., Takahashi, S., Saito, K. and Kato, H. DNA microarray analysis
identified molecular pathways mediating the effect of the supplementation
of branched amino acids on CCl4-induced cirrhosis in rats. Mol. Nutr. Food
Res. 57, 291-306 (2013)
Wu, T., ZhuGe, F., Sun, L., Ni, Y., Fu, O., Gao, G., Chen, J., Kato, H.
and Fu, Z. Enhanced effect of daytime restricted feeding on the circadian
rhythm of streptozotocin-induced type 2 diabetic rats. Am. J. Physiol.
Endocrinol. Metab, 302, E1027-1035 (2012)
Ha, B.G., Nagaoka, M., Yonezawa, T., Tanabe, R., Woo, J.T., Kato, H., Chung,
U.I. and Yagasaki, K. Regulatory mechanism for the stimulatory action of
genistein on glucose uptake in vitro and in vivo. J. Nutr. Biochem 23,
501-509 (2012)
Otani, L., Sugimoto, N., Kaji, M., Murai, M., Chang, S.-J., Kato, H. and
Murakami, T. Role of the renin-angiotensin-aldosterone system in the enhancement
of salt sensitivity caused by prenatal protein restriction in stroke-prone
spontaneously hypertensive rats. J. Nutr. Biochem. 23, 892-899 (2012)
加藤久典 第1章 アミノ酸の機能 「機能性アミノ酸・ペプチドの技術と市場」、シーエムシー出版、pp3-11 (2012)
勝呂栞、山岸淑恵、大谷りら、加藤久典 シスチンの生体における定量とその応用 Food Style 21, 16(7), 31-35 (2012)
佐藤隆一郎、加藤久典(編集)「食べ物と健康」(吉田勉監修)学文社 (2012)
佐藤隆一郎、加藤久典(編集)「基礎栄養学」(吉田勉監修)学文社 (2012)
Otani, L., Ogawa, S., Zhao, Z., Nakazawa, K., Umehara, S., Yoshimura, E.,
Chang, S.-J. and Kato, H. An Optimized Method for the Determination of
Free L-Cysteine in Rat Plasma by High-Performance Liquid Chromatography
Using the Derivatization Reagent 4-Aminosulfonyl-7-Fluoro-2,1,3-Benzoxadiazole.
Biosci. Biotechnol. Biochem. 75, 2119-2124 (2011)
Jia, H., Ren, H., Deng, C., Kato, H. and Endo, H. Evaluation of the antioxidant
potential of Chinese parsley (Coriandrum sativum) as compared with a synthetic
antioxidant in diet. Int. J. Food Prop. in press.
Jia, H., Ren, H., Deng, C., Kato, H. and Endo, H. Antioxidant potential
of Western parsley (Petroselinum crispum) extract and its effects on oxidative
stabilities of food during storage. J. Food Biochem. in press
Wu, T., Sun, L., ZhuGe, F, Guo, X., Zhao, Z., Tang, R., Chen, Q., Chen,
L., Kato, H. and Fu, Z. Differential roles of breakfast and supper in rats of a daily
three-meal schedule upon circadian regulation and physiology. Chronobiol.
Int. 28, 890-903
Takahashi, S., Masuda, J., Shimagami, H., Ohta, Y., Kanda, T., Saito, K.
and Kato, H. Mild caloric restriction up-regulates the expression of prohibitin:
A proteome study. Biochem. Biophys. Res. Commun. 405, 462-467
Ono, T., Morishita, S., Fujisaki, C., Ohdera, M., Murakoshi, M., Iida,
N., Kato, H., Miyashita, K., Iigo, M., Yoshida, T., Sugiyama, K. and Nishino,
H. Effects of pepsin and trypsin on the anti-adipogenic action of lactoferrin
against pre-adipocytes derived from rat mesenteric fat. Brit. J. Nutr.
105, 200-211
.
Wu, T., Ni, Y., Zhue, F., Sun, L., Xu, B., Kato, H. and Fu, Z. Significant
dissociation of expression patterns of the basic helix-loop-helix transcription
factors Dec1 and Dec2 in rat kidney. J. Exp.Biol. 214 (Pt. 8), 1257-1263
Kato, H., Takahashi, S. and Saito, K. Omics and integtrated omics for the
promotion of food and nutrition science. J. Trad. Comp. Med. 1, 25-30 (2011)
加藤久典 分子栄養学―遺伝子の働きから探る食品機能、バイオテクニシャン、19 (2)、6-14 (2011)
Dong, Y., Wu, T., Ni, Y.H., Kato, H., Fu, Z.W. Effect of fasting on the
peripheral circadian gene expression in rats. Am. J. Physiol. Regul. Integr.
Comp. Physiol.298, 635-641
Wu, T., Ni, Y., Dong, Y., Kato, H. and Fu, Z.W. Regulation of circadian
gene expression in the kidney by light and food cues in rats. Biol. Rhythm
Res. 41, 41-47
Saito, K., Ohta, Y., Sami, M., Kanda, T. and Kato, H. Effect of mild restriction
of food intake on gene expression profile in the liver of young rats: reference
data for in vivo nutrigenomics study. Brit. J. Nutr. 104, 941-950
Kamei, A., Watanabe, Y., Ishijima, T., Uehara, M., Arai, S., Kato, H.,
Nakai, Y. and Abe, K. Dietary iron deficiency induces a variety of metabolic
changes and even apoptosis in rat liver: a DNA microarray study. Physiol.
Genomics. 42,149-156
Wu, T., Ni, Y., Kato, H. and Fu, Z. Feeding-induced rapid resetting of
the hepatic circadian clock is associated with acute induction of Per2
and Dec1 transcription in rats. Chronobiol. Int. 27, 1-18.
Toyoshima, Y, Tokita, R., Ohne, Y., Hakuno, F., Noguchi, T., Minami, S.,
Kato, H. and Shin-Ichiro Takahashi, S.I. Dietary protein deprivation up-regulates
insulin signaling and inhibits gluconeogenesis in rat liver. J. Mol. Endocrinol.45,
329-340.
矢ヶ崎一三、末安俊明、河秉瑾、伊東克晃、米澤貴之、加藤久典 大豆イソフラボンによるインスリン抵抗性の克服とトランスクリプトームおよびプロテオーム解析による機能解明(第二報)、大豆たん白質研究、13,
23-29 (2010)
Abe, K., Kato, H., Yasuoka, A. and Nakai, Y. Genomics applied to nutrients
and functional foods in Japan: State of the art. In: Genomics, proteomics,
and metabolomics in nutraceuticals and functional foods. Bagchi, D., Lau,
F.C. and Bagchi, M (eds) Wiley-Blackwell, U.S.A. pp127-154
加藤久典 1.9 トランスクリプトーム解析 (第5章大豆の機能性、第1節タンパク質の機能性)「大豆のすべて」(喜多村啓介他編集)、サイエンスフォーラム、pp185-188
高橋伸一郎、竹中麻子、豊島由香、木村久美、加藤久典、福島俊明、山中大介、伯野史彦、南史朗、岩下光利 発達と成長を司るホルモン、インスリン様成長因子 日本未熟児新生児学会雑誌、22,
19-25
加藤久典 第12章 網羅的遺伝子発現解析を利用した食品の安全性評価、「食の安全科学の展開-食のリスク予測と制御に向けて」(東京大学食の安全研究センター編)、シーエムシー出版、pp98-102
Srinivasan, V., Pandi-Perumal, S.R., Spence, W., Kato, H. and Cardinali,
D.P. Melatonin in septic shock: Some recent concepts. J. Crit. Care, 25,
656.e1-656.e6
加藤久典、斉藤憲司 第6節 食品データベース(第4章 食品分野への応用)、「バイオチップ実用化ハンドブック」(金子周一、堀池靖浩編)、エヌ・ティー・エス、pp346-352
加藤久典 4章5 窒素化合物の代謝 「現代栄養学を理解するための分子生物学入門」 (加藤茂明編著)光生館 pp106-114
大谷りら、加藤久典、村上哲男 胎内の低栄養環境で生じる高血圧の発症機序 医学のあゆみ、235, pp833-837
Otani, L., Ninomiya, T., Murakami, M., Osajima, K., Kato, H. and Murakami,
T. Sardine peptide with angiotensin I converting enzyme inhibitory activity
improves glucose tolelance in stroke-prone spontaneously hypertensive rats.
Biosci. Biotechnol. Biochem. 73, 2203-2209
Wu, T., Dong, Y., Yang, Z.Q., Kato, H., Ni, Y.H., Fu, Z.W. Differential
resetting process of circadian gene expression in rat pineal glands after
the reversal of the light/dark cycle via a 24-h light or dark period transition.
Chronobiol. Int. 26, 793-807
Hirao, T., Watanabe, S., Temmei, Y., Hiramoto, M. and Kato, H. Qualitative
PCR methods for detecting major food allergens (peanut, soybean, and wheat)
by using internal transcribed spacer region. J. AOAC Int. 92, 1464-1472
加藤久典 第7章(訳)高齢者を含む成人と妊婦、授乳婦のタンパク質必要量「タンパク質・アミノ酸の必要量 WHO/FAO/UNU合同専門協議会報告」(日本アミノ酸学会翻訳小委員会)医歯薬出版 pp79-102
矢ケ崎一三、末安俊明、河秉瑾、長岡真聡、米沢貴之、 加藤久典 「大豆イソフラボンによるインスリン抵抗性の克服とトランスクリプトーム解析による機能解明」 (第一報) 大豆たん白質研究、12、pp22-26
Wu, T., Jin, Y.X., Kato, H. and Fu, Z.W. Light and food signals cooperate
to entrain the rat pineal circadian system. J. Neurosci. Res. 86, 3246-3255
Niwa, Y., Nishiyama, C., Nakano, N., Kamei, A., Kato, H., Kanada, S., Ikeda,
S., Ogawa, H. and Okumura, K. Opposite effects of PU.1 on mast cell stimulation.
Biochem. Biophys. Res. Commun. 375, 95-100
Wu, T., Jin, Y.X., Ni, Y.H., Zhang, D.P., Kato, H. and Fu, Z.W. Effects
of light cues on re-entrainment of the food-dominated peripheral clocks
in mammals. Gene, 419, 27-34
Nakai, N., Hashida, H., Kadota, K., Minami, M., Shimizu, K., Matsumoto,
I., Kato H. and Abe, K. Genes related to the ubiquitin-proteasome system
are up-regulated in the brown adipose tissue of 24 h-fasted rats. Biosci.
Biotechnol. Biochem. 72, 139-148
Hirao, T., Watanabe, S., Hiramoto, M., Taguchi, H., Temmei, Y. and Kato,
H. Qualitative and quantitative PCR methods for detecting food allergens
by using internal transcribed spacer region. J. Clin. Biochem. Nutr. 43(S1),
227-231
Kato, H. Nutrigenomics: the cutting edge and Asian perspectives. Asia Pac.
J. Clin. Nutr. 17(S1), 12-15
加藤久典、中井雄治、阿部啓子 1.ゲノミクス、プロテオミクス、メタボロミクスおよびシステムバイオロジーと、その栄養学へのアプローチ(訳)「最新栄養学 第9版」(木村修一、小林修平翻訳監修)建帛社、pp3-20
加藤久典、辻真之介 コレステロール負荷時における大豆たん白質摂取の効果のトランスクリプトーム解析、大豆たん白質研究、10, 76-82
加藤久典 第1編 第5章 抗肥満食品のマイクロアレイ解析 「抗肥満食品・素材の開発と応用展開」(大澤俊彦監修)シーエムシー出版、pp59-68
西山真, 加藤久典, 吉田稔, 山口五十麿, 宮川都吉, 小鹿一, 小梅枝正和, 日岡康恵 電子投稿審査システムの導入とその影響:日本農芸化学会の経験.
情報管理、50, 429-436
加藤久典、小林進、勝谷友宏、三谷康正 ニュートリゲノミクスの新潮流-テーラーメード栄養を身近なものに、バイオサイエンスとインダストリー、65,
19-23
加藤久典、第IV編 機能性食品とニュートリゲノミクス-3.実施例、同-5.安全性ゲノミクス「機能性食品の事典」、(荒井綜一ら編)朝倉書店、pp394-399,
pp428-430
加藤久典、林裕三、高橋迪雄、古屋茂樹、岸恭一、門脇基二 進化の観点からアミノ酸栄養を考える、日本栄養・食糧学会誌、60, 151-166
加藤久典 第5章 アミノ酸機能のニュートリゲノミクス解析 「アミノ酸の機能特性-ライフサイエンスにおける新しい波-」(日本栄養・食糧学会監修)建帛社、pp171-187
加藤久典、第7章 アミノ酸による遺伝子発現の調節 「タンパク質・アミノ酸の新栄養学」(岸恭一、木戸康博編)講談社、pp82-94
野口忠、加藤久典、大石祐一、第2章 タンパク質・アミノ酸代謝 「タンパク質・アミノ酸の科学」(日本必須アミノ酸協会編)工業調査会、pp65-115
Hirao, T., Hiramoto, M., Imai, S. and Kato, H. A novel PCR method for quantification
of buckwheat using a unique internal standard material. J. Food. Protect.
69, 2478-2486
Ohta, Y., Sami, M., Kanda, T., Saito, K., Osada, K. and Kato, H. Gene expression
analysis of the anti-obesity effect by apple polyphenols in rats fed a
high fat diet or a normal diet. J. Oleo Sci. 55, 305-314
Narasaka, S., Endo, Y., Fu, ZW., Moriyama, M., Arai, S., Abe, K. and Kato,
H. Safety evaluation of hypoallergenic wheat flour using a DNA microarray.
Biosci. Biotechnol. Biochem. 70, 1464-1470
加藤久典、辻真之介、食生活を視野に入れた大豆たん白質機能のニュートリゲノミクス解析、大豆たん白質研究、9, 102-107 (2006)
加藤久典、7.2.食品機能のDNAマイクロアレイ解析の具体例、「アンチエイジングと機能性食品」(吉川敏一、大澤俊彦編)シーエムシー出版、pp214-220
加藤久典、DNAチップを用いた食品の機能性評価、ジャパンフードサイエンス、45, 70-76
加藤久典、吉澤史昭、2.5.2.タンパク質の生合成 「栄養・食糧学データハンドブック」(日本栄養・食糧学会編)同文書院、pp87-90
Saito, K., Arai, S. and Kato, H. A nutrigenomics database - Integrated
repository for publications and associated microarray data in nutrigenomics
research. Brit. J. Nutr. 94, 493-495
Ohne, Y., Toyoshima, Y. and Kato, H. Disruption of the availability of
amino acids induces a rapid reduction of serine phosphorylation of insulin
receptor substrate-1 in vivo and in vitro. Biosci. Biotechnol. Biochem.
69, 989-998
Tachibana, N., Matsumoto, I., Fukui, K., Arai, S., Kato, H., Abe, K. and
Takamatsu, K. Intake of soy protein isolate alters hepatic gene expression
in rats. J. Agric. Food Chem. 53, 4253-4257
Hirao, T., Imai, S., Sawada, H., Shiomi, N., Hachimura, S. and Kato, H.
PCR method for detecting trace amounts of buckwheat (Fagopyrum spp.) in
food. Biosci. Biotechnol. Biochem. 69, 724-731
Kato, H., Saito, K. and Kimura, T. A perspective on DNA microarray technology
in food and nutritional science. Curr. Opin. Clin. Nutr. Metab. Care, 8,
516-522
Matsuzaki, K., Kato, H., Sakai, R., Toue, S., Amao, M. and Kimura, T. Transcriptomics
and metabolomics of dietary leucine excess. J. Nutr. 135, 1571S-1575S
小田裕昭、加藤久典、関泰一郎(編著)「健康栄養学-健康科学としての栄養生理化学-」共立出版
加藤久典 5.4. 内分泌系における食情報の受容と伝達 「食品の科学」(上野川修一、田之倉優編)東京化学同人、pp134-138
加藤久典 栄養学の新しい潮流-分子栄養学からニュートリゲノミクスへ、食品と技術、404, 1-9
加藤久典 タンパク質の機能性・安全性予測のためのトランスクリプトミクス、日本食品新素材研究会誌 7, 1-7
加藤久典 食餌タンパク質の機能解析とトランスクリプトミクス、日本臨床栄養学会雑誌26, 207-211
Toyoshima, Y., Ohne, Y., Takahashi, S.-I., Noguchi, T. and Kato, H. Dietary protein deprivation decreases the serine phosphorylation of insulin receptor substrate-1 in rat skeletal muscle. J. Mol.Endocrinol. 32, 519-531
太田豊、長田恭一、船山誠、佐見学、神田智正、加藤久典、ジーンチップによる肥満誘導食摂取ラットに与えるポリフェノール素材投与効果の解析.脂質生化学研究
46, 160-163
Kato, H., Narasaka, S., Endo, Y., Abe, K. and Arai, S. DNA microarray analyses
of the effects of dietary proteins. Biofactors 21, 11-13
加藤久典 第8章タンパク質(共著、野口忠)、第14章消化・吸収 「基礎栄養学」(倉田忠男他編)東京化学同人 pp80-107, pp184-197
加藤久典 第15章 栄養と遺伝子科学(訳)「ヒューマン・ニュートリション、基礎・食事・臨床」(細谷憲政監修)医歯薬出版 pp299-309
Imae, M., Fu, ZW., Yoshida, A., Noguchi, T. and Kato, H. Nutritional and
hormonal factors control the gene expression of FoxOs, the mammalian homologues
of DAF-16. J. Mol. Endocrinol.30, 253-262
Oishi, Y., Kato, H. and Noguchi, T. Dietary protein is a potent regulator
of the hyaluronan synthase gene in rat skin. Biosci. Biotechnol. Biochem.
67, 736-742
加藤久典 15章 窒素の代謝II:分解(訳)「マッキー生化学 第3版」(市川厚監修)化学同人 pp459-484
加藤久典 3.3.3 a. 分子栄養学、3.3.3.b.2) ホルモンと栄養 「農芸化学の事典」(鈴木昭憲、荒井綜一編)朝倉書店 pp424-426,
pp429-431
Kato, H. and Kimura, T. Evaluation of the effects of the dietary intake
of proteins and amino acids by DNA microarray technology. J. Nutr. 133,
2073S-2077S
Fu,ZW., Yoneyama, M., Noguchi, T. and Kato , H. Response of the IGF system
to vitamin A depletion and repletion in rats. J. Nutr. Sci. Vitaminol.48,
453-460
Endo, Y., Fu, Z.W., Abe, K., Arai, S. and Kato, H. Dietary protein quantity
and quality affect rat hepatic gene expression. J. Nutr.132, 3632-3637
Oishi, Y., Fu, Z.W., Ohnuki, Y., Kato, H. and Noguchi, T. Molecular basis
of the alteration in skin-collagen metabolism in response to in vivo dexamethasone
treatment: Effects on syntheses of collagen type I and III, collagenase,
and TIMPs. Brit. J. Dermatol.147, 859-868
Tachibana, T., Tanaka, S., Furuse, M., Hasegawa, S., Kato, H. and Sugahara,
K. Intracerebroventricular injection of glucagon-like peptide-1 decreases
monoamine concentrations in the hypothalamus of chicks. Brit. Poultry Sci.
43, 122-126
Oishi, Y., Fu, Z.W., Ohnuki, Y., Kato, H. and Noguchi, T. Effects of protein
deprivation on a1(I) and a1(III) collagen and its degrading system in rat
skin. Biosci. Biotechnol. Biochem. 66, 117-126
Fu, Z.W., Inaba, M., Noguchi, T. and Kato, H. Molecular cloning and circadian
regulation of cryptochrome genes in the Japanese quail (Coturnix coturnix
japonica). J. Biol. Rhythms17, 14-27
加藤久典 タンパク質代謝の分子栄養学 「分子栄養学 栄養素と生活習慣病の分子生物学」(柿沼淳司編著)光生館 pp50-64
Fu, Z.W., Kato, H, Kotera, N., Noguchi, T., Sugahara, K. and Kubo, T. Regulation
of hydroxyindole-O-methyltransferase gene expression in Japanese quail
(Coturnix coturnix japonica). Biosci. Biotechnol. Biochem.65, 2504-2511
Matsukawa, T., Inoue, Y., Oishi, Y., Kato, H. and Noguchi, T. Up-regulation
of upstream stimulatory factors by protein malnutrition and its possible
role in regulation of the IGF-binding protein-1 gene. Endocrinology 142,
4643-4651
Fu, ZW., Noguchi, T. and Kato, H. Differential regulation of IGFBP-2 and
IGFBP-5 gene expression by vitamin A status in Japanese quail. Am. J. Physiol.281,
E138-E146
Fu, ZW., Kubo, T., Sugahara, K., Noguchi, T. and Kato, H. Retinoid nutritional
status differently affects the expression of quail RARb isoform transcripts
in a tissue-specific manner. J. Endocrinol. 169, 281-290
Fu, ZW., Noguchi, T. and Kato, H. Vitamin A deficiency reduces IGF-I gene
expression and increases IGF-I receptor and insulin receptor gene expression
in tissues of Japanese quail (Coturnix coturnix japonica). J. Nutr.131,
1189-1194
Fu, ZW, Kubo, T., Noguchi, T. and Kato, H. Developmental changes in the
mRNA levels of IGF-I and its related genes in the reproductive organs of
Japanese quail (Coturnix coturnix japonica) Growth Horm. IGF Res.11, 24-33
Fu, ZW, Kubo, T., Sugahara, K, Noguchi, T. and Kato, H. Cloning of cDNAs
encoding quail (Coturnix coturnix japonica) retinoic acid receptor b isoforms
and changes in their gene expression during gonadotropic growth. Biol.
Reprod. 64, 231-241
加藤久典 分子生物学的手法 「動物栄養試験法」(石橋晃監修) pp380-394
Tachibana, T., Uchimura, D., Kato, H., Kubo, T. and Sugahara, K. Extracellular
norepinephrine in the medial hypothalamus increases during feeding in chicks:
A microdialysis study. Comp. Biochem. Physiol. 127A, 331-338
Imae, M., Inoue, Y., Fu, ZW., Kato, H. and Noguchi, T. Gene expression
of the three members of hepatocyte nuclear factor-3 is differentially regulated
by nutritional and hormonal factors. J. Endocrinol.167, R1-R5
Fu, ZW., Kato, H. Sugahara, K and Kubo, T. Retinoic acid accelerates the
development of reproductive organs and egg production in Japanese quail
(Coturnix coturnix japonica). Biol. Reprod. 63, 1795-1800
Kato, H., Okubo, Y., Matsumura, Y., Roberts, C.T., Jr., Sugahara, K. and
LeRoith, D. The tyrosine kinase activity of the chicken insulin receptor
is similar to that of the human insulin receptor. Biosci. Biotechnol. Biochem.64,
903-906
加藤久典 初代培養肝細胞「タンパク質代謝研究法」(野口忠、舩引龍平、門脇基二編著)学会出版センター pp115-128
加藤久典 内分泌調節機能 「食品機能研究法」(篠原和毅、鈴木建夫、上野川修一編)、光琳 pp103-105
Sugahara, K., Shimoyama, Y., Kato, H. and Kubo, T. Feeding a lysine-free
diet decreases food intake without changes in hypothalamic monoamine concentrations
in growing chickens. Anim. Sci. Technol. (Jpn.)70, 484-489
Fu, ZW., Kato, H., Kotera, N., Sugahara, K. and Kubo, T. Regulation of
the expression of serotonine N-acetyltransferase gene in Japanese quail
(Coturnix japonica): (II) Effect of vitamin A deficiency. J. Pineal Res.27,
34-41
Kato, H., Fu, ZW., Kotera, N., Sugahara, K. and Kubo, T. Regulation of
the expression of serotonine N-acetyltransferase gene in Japanese quail
(Coturnix japonica): (I) Rhythmic pattern and effect of light. J. Pineal
Res.27, 24-33
Tsuchiya, T., Nagao, Y., Ozawa, A., Matsumoto, M., Sugahara, K., Kubo,
T. and Kato, H. Decrease of the obese gene expression in bovine subcutaneous
adipose tissue by fasting. Biosci.Biotechnol. Biochem. 62, 2068-2069
Fu, ZW., Kato, H., Sugahara, K. and Kubo, T. Circadian rhythm of pineal
melatonin contents in silky chicks. Jpn. Poult. Sci. 35, 55-59
Fu, ZW., Kato, H., Sugahara, K. and Kubo, T. Vitamin A deficiency reduces
the responsiveness of pineal gland to light in Japanese quail (Coturnix
japonica). Comp. Biochem. Physiol. 119A, 593-598
傅正偉、近藤康、岩崎信久、加藤久典、菅原邦生、久保辰雄 ニワトリヒナ松果体中メラトニンの抽出法と高速液体クロマトグラフィーによる定量法、日本畜産学会報、68,
1154-1160
Shim, S., Fu, ZW., Kato, H. and Tanaka, H. Diurnal changes in the enzyme
activity and the messenger RNA level of pineal serotonin N-acetyltransferase
in normal and hereditary microphthalmic rats. Biosci. Biotechnol. Biochem.
61, 2113-2115.
Fu, ZW., Kubo, T. and Kato, H. Analyses of serotonin N-acetyltransferase
mRNA content in rat pineal grand and testis by an improved assay system
- Micro lysate assay. Anim. Sci. Technol.(Jpn.)68, 893-896
Fu, ZW., Ohara, S., Kato, H., Sugahara, K. and Kubo, T. Retinoic acid accelerates
the testicular maturation in Japanese quail. Anim. Sci. Technol (Jpn) 68,
420-422
Najjar, S.M., Blakesley, V.A., Li Calzy, S., Kato, H., LeRoith, D. and
Choice, C.V. Differential phosphorylation of pp120 by insulin and insulin-like
growth factor-1 receptors: Role for the C-terminal domain of the b-subunit.
Biochemistry 36, 6827-6834
加藤久典、傅正偉 遺伝子レベルでの栄養研究-多様なmRNA種をつくる遺伝子について、日本栄養・食糧学会誌、50, 377-379
加藤久典 IGF-Iの作用発現機構に関する分子生物学的研究、日本農芸化学会誌 71, 1141-1146
Matsumura, Y., Domeki, M., Sugahara, K., Kubo, T., Roberts, C.T., Jr., LeRoith, D. and Kato, H. Nutritional regulation of insulin-like growth factor-I receptor mRNA levels in growing chickens. Biosci. Biotechnol. Biochem. 60, 979-982
Kato, H., Noguchi, T. and LeRoith, D. Nutritional regulation of gene expression of IGFs and their related proteins. In: Gene expression and nutrition: From cells to whole body. Muramatsu, T. (ed) Research Signpost, India, pp25-43
Stannard, B., Blakesley, V.A., Kato, H., Roberts, C.T., Jr. and LeRoith,
D. Single tyrosine substitution in the insulin-like growth factor I receptor
inhibits ligand-induced receptor autophosphorylation and internalization,
but not mitogenesis. Endocrinology 136, 4918-4924
Surmacz, E., Sell, C., Swantek, J., Kato, H., Roberts, C.T., Jr., LeRoith,
D. and Baserga, R. Dissociation of mitogenesis and transforming activity
by C-terminal truncation of the insulin-like growth factor-I receptor.
Exp. Cell. Res.218, 370-380
Blakesley, V.A., Kato, H., Roberts, C.T., Jr. and LeRoith, D. Mutation
of a conserved amino acid residue (tryptophan 1173) in the tyrosine kinase
domain of the IGF-I receptor abolishes autophosphorylation but does not
eliminate biologic function. J. Biol. Chem. 270, 2764-2769
Mastick, C.C., Kato, H., Roberts, C.T., Jr., LeRoith, D. and Saltiel, A.R.
Insulin and insulin-like growth factor-I receptors similarly stimulate
deoxyribonucleic acid synthesis despite differences in cellular protein
tyrosine phosphorylation. Endocrinology 135, 214-222
Faria, T.N., Blakesley, V.A., Kato, H., Stannard, B., LeRoith, D. and Roberts,
C.T.,Jr. Role of the carboxyl-terminal domains of the insulin and insulin-like
growth factor I receptor function. J. Biol. Chem. 269, 13922-13928
Kato, H., Faria, T.N., Stannard, B., Roberts, C.T.,Jr. and LeRoith, D.
Essential role of tyrosine residues 1131, 1135 and 1136 of the insulin-like
growth factor-I (IGF-I) receptor in IGF-I action. Mol. Endocrinol. 8, 40-50
Kato,H., Faria, T.N., Blakesley, V., Roberts, C.T., Jr. and LeRoith, D. Pathological alterations in various components of the insulin-like growth factor signalling system. In: Molecular basis of endocrine diseases (Series: Frontiers in endocrinology 7) Isidori, A., New, M.I., Sesma, C.P.(eds) Ares-Serono Symposia Publications, Rome, pp105-118
Takenaka, A., Hirosawa, M., Mori, M., Yamada, S., Miura, Y., Kato, H.,
Takahashi, S.I. and Noguchi, T. Effect of protein nutrition on the messenger
RNA content of insulin-like growth factor binding protein-1 in liver and
kidney of rats. Brit. J. Nutr.69, 73-82
Kato, H., Faria, T.N., Stannard, B., Levy-Toledano, R., Taylor, S.-I.,
Roberts, C.T., Jr. and LeRoith, D. Paradoxical biological effects of overexpressed
insulin-like growth factor-I receptors in Chinese hamster ovary cells.
J. Cell. Physiol. 156, 145-152
Kato, H., Faria, T.N., Stannard, B., Roberts, C.T., Jr. and LeRoith, D.
Role of tyrosine kinase activity in signal transduction by the insulin-like
growth factor-I (IGF-I) receptor. Characterization of kinase-deficient
IGF-I receptors and the action of IGF-I mimetic antibody (aIR-3). J. Biol.
Chem.268, 2655-2661
LeRoith, D., Werner, H., Faria, T.N., Kato, H., Adamo, M. and Roberts,
C.T., Jr. Insulin-like growth factor receptors - Implications for nervous
system function. In: Role of insulin-like growth factors in the nervous
systems.Raizada, M.K. and LeRoith, D. (eds.) New York Academy of Science,
New York, pp23-32
LeRoith, D., Adamo, M., Kato, H. and Roberts, C.T., Jr. Divergence of insulin
and insulin-like growth factor-I signalling pathways. In: Lessons from
Laron syndrome. Laron, Z. and Parks, J.S.(eds.) Karger, Basel, pp346-358
Miura, Y., Higashi, Y., Kato, H., Takahashi, S.-I. and Noguchi, T. Effects
of dexamethasone on the production of insulin-like growth factor-I and
insulin-like growth factor binding proteins in primary cultures of rat
hepatocytes. Biosci. Biotechnol. Biochem. 56, 1396-1400
Miura, Y., Kato, H. and Noguchi, T. Effect of dietary proteins on insulin-like
growth factor-I (IGF-I) messenger ribonucleic acid content in rat liver.
Brit. J. Nutr. 67, 257-265
LeRoith, D., McGuiness, M., Shemer, J., Stannard, B., Lanau, F., Faria, T.N., Kato, H., Werner, H., Adamo, M. and Roberts, C.T.,Jr. Insulin-like growth factors. Biosignals 1, 173-181
Takenaka, A., Miura, Y., Mori, M., Hirosawa, M., Kato, H. and Noguchi,
T. Distribution of messenger RNAs of insulin-like growth factor (IGF)-binding
proteins-1 and -3 between parenchymal and nonparencymal cells in rat liver.
Agric. Biol. Chem. 55, 1191-1193
Umezawa, T., Kajikawa, M., Ohsawa, Y., Miura, Y., Kato,H. and Noguchi,
T. Effect of protein deprivation on insulin-like growth factor-binding
proteins in rats. Brit. J. Nutr. 66, 105-116
Kato, H., Umezawa, T., Miura, Y. and Noguchi, T. The effect of quantity and nutritional quality of dietary proteins on plasma concentration of insulin-like growth factor binding proteins (IGFBP) and the saturability of IGFBP with endogenous IGF-I. Adv Exp Med Biol. 293, 171-178
Takahashi, S., Kajikawa, M., Umezawa, T., Takahashi, S.-I., Kato, H., Miura,
Y., Nam, T.J., Noguchi, T. and Naito, H. Effect of dietary proteins on
the plasma immunoreactive insulin and insulin-like growth factor-I/somatomedin
C concentration in the rat. Brit. J. Nutr. 63, 521-534
Nam, T.J., Noguchi, T., Funabiki, R., Kato, H., Miura, Y. and Naito, H.
Correlation between the urinary excretion of acid soluble peptides, fractional
synthesis rate of whole body proteins, and plasma insulin-like growth factor-I/somatomedin
C concentration in the rat. Brit. J. Nutr. 63, 515-520
Kato, H., Takenaka, A., Miura, Y., Nishiyama, M. and Noguchi, T. Evidence
of introduction by molecular cloning of artificial inverted sequence at
the 5' terminus of the sense strand of rat insulin-like growth factor-I
cDNA. Agric. Biol. Chem. 54, 2225-2230
Kato, H., Okoshi, A., Miura, Y. and Noguchi, T. A new cDNA clone relating
to larger molecular species of rat insulin-like growth factor-I mRNA. Agric.
Biol. Chem. 54, 1599-1601
Takahashi, S.-I., Ohishi, Y., Kato, H., Noguchi, T., Naito, H. and Aoyagi,
T. The effects of bestatin, a microbial aminopeptidase inhibitor, on epidermal
growth factor- induced DNA synthesis and cell division in primary cultured
hepatocytes of rats. Exp. Cell Res. 183, 399-412
Takenaka, A., Tayama, T., Takahashi, S.-I., Kato, H., Noguchi, T. and Naito,
H. Microinjection of endogenous proteins into primary cultures of rat hepatocytes
and the degradation of the injected proteins. Int. J. Biochem. Cell Biol.
21, 497-508
Kato, H., Takahashi, S.-I., Takenaka, A., Funabiki, R., Noguchi, T. and
Naito, H. Degradation of endogenous proteins and internalized asialofetuin
in primary cultured hepatocytes of rats. Int. J.Biochem.Cell Biol. 21,
483-495
Kato, H., Miura, Y., Okoshi, A., Umezawa, T., Takahashi, S.-I. and Noguchi,
T. Dietary and hormonal factors affecting the mRNA level of IGF-I in rat
liver in vivo and in primary cultures of rat hepatocytes. In: Molecular
and cellular biology of insulin-like growth factors and their receptors.
LeRoith, D. and Raizada, M. (eds.) Plenum, New York, pp125-128
Noguchi, T., Tayama, T., Takenaka, A., Takahashi, S.-I., Kato,H. and Naito,
H. Microinjection of endogenous and exogenous proteins into primary cultured
hepatocytes and degradation of the injected proteins. In: Intracellular
proteolysis: Mechanism and regulations. Katunuma, N. and Kominami, E (eds.)
Japan Scientific Societies Press, Tokyo, pp485-487
Kato, H., Takahashi, S.-I., Funabiki, R., Noguchi, T. and Naito, H. Mechanism
and rate of degradation of short- and long-lived proteins in primary cultured
rat hepatocytes. In: Intracellular proteolysis: Mechanism and regulations.
Katunuma, N. and Kominami, E (eds.)
Takahashi, S.-I., Kato, H., Seki, T.-I., Takahashi, A., Noguchi, T. and
Naito, H. Intermediate peptides of insulin degradation in liver and cultured
hepatocytes of rats. Int. J. Biochem. Cell Biol. 20, 1369-1380
Noguchi, T., Nam, T.J., Kato, H. and Naito, H. Further studies on the nutritional
factors affecting the urinary excretion of acid-soluble peptides in rats.
Brit. J. Nutr. 60, 321-337
Takahashi, S.-I., Kato, H., Takahashi, A., Noguchi, T. and Naito, H. Mode of action of bestatin and leupeptin to induce the accumulation of acid soluble peptides in rat liver in vivo and the properties of the accumulated peptides. The important role of bestatin- and leupeptin- sensitive proteases in the protein degradation pathway in vivo. Int. J. Biochem. Cell Biol. 19, 401-412
加藤久典 インスリン様成長因子とタンパク質代謝 日本農芸化学会誌 16, 1305-1308
Takahashi, S.-I., Kato, H., Seki, T.-I., Noguchi, T., Naito, H., Aoyagi, T. and Umezawa, H. Bestatin, a microbial aminopeptidase inhibitor inhibits DNA synthesis induced by insulin or epidermal growth factor in primary cultured rat hepatocytes. J. Antibiot. 38, 1767-1773 (1985)
Japan-New Zealand Joint Workshop on “Functional Food”(2010/10/12)
12th Japanese-Swiss Meeting on Biotechnology and Bioprocess Development(2010/10/10-12)
日本農芸化学会関西支部シンポジウム(2010/10/2)
日本アミノ酸学会第4回学術大会(2010/9/16-17)
核酸・核 タンパク機能性研究会 第5回学術集会(2010/8/6)
第64回日本栄養・食糧学会大会(2010/5/21-23)
日本農芸化学会2010年度大会(2010/3/27-30)
日本アーユルヴェーダ学会総会(2009/12/12)
第32回日本分子生物学会年会(2009/12/9-12)
第3回食品薬学シンポジウム(2009/11/12)
19th International Congress of Nutrition (2009/10/4-9)
日本アミノ酸学会 第3回学術大会(2009/09/29-30)
第84回日本栄養・食糧学会関東支部会(2009/09/19)
核酸・核タンパク機能性研究会 第4回学術集会(2009/07/31)