About "Interfacial Molecular Engineering Laboratory" starting from 2022/4, please visit here.
Dr. Yoshimitsu Itoh was born 1977 in Kanagawa, Japan. He received a Ph.D. degree for experimental and theoretical investigation of organo-fluorine compounds under the direction of Prof. Koichi Mikami at Tokyo Institute of Technology in 2006. Then, he started his first postdoctoral research focusing on organometallic catalysis with Prof. Eiichi Nakamura at the University of Tokyo. His second postdoctoral research was carried out in Columbia University starting from 2007 with Prof. Colin Nuckolls working on self-assembled monolayers and organic field effect transistors. In 2008, he began his academic career at the University of Tokyo as an assistant professor in Prof. Takuzo Aida’s group. He was promoted to Lecturer in 2016 and then to Associate Professor in 2019. He is now interested in modulation of chemical systems (reaction, assembly, property) using electric field for the development of novel functional materials.
Education
BS. Faculty of Engineering, Tokyo Institute of Technology (2001)
MS. Graduate School of Engineering, Tokyo Institute of Technology (2003)
Ph.D Graduate School of Engineering, Tokyo Institute of Technology (2006)
Antecedents
2001.4–2006.3: Graduate Student, Tokyo Institute of Technology (supervisor Prof. Koichi Mikami)
2005.7–2005.9: Visiting Graduate Student, University of California, Los Angels (Prof. K. N. Houk group)
2006.4–2007.8: JSPS Research Fellow, The University of Tokyo (Prof. Eiichi Nakamura group)
2007.9–2008.8: JSPS Research Fellow, Columbia University (Prof. Colin Nuckolls group)
2008.9–2016.9: Assistant Professor, The University of Tokyo
2016.10–2019.5: Lecturer, The University of Tokyo
2019.6–present: Associate Professor, The University of Tokyo
Awards
2013: Gordon Research Conference (Self-Assembly & Supramolecular Chemistry) Emerging Leaders Award.
2016: Chemical Society of Japan, Lecture Award for Young Chemist.
2017: The Young Scientists’ Prize in The Commendation for Science and Technology by the Minister of Education,
Culture, Sports, Science and Technology
2018: SPSJ Publicity Prize
2019: SPSJ Publicity Prize
2019: SPSJ Hitachi Chemical Award
Publications
Alternating Heterochiral Supramolecular Copolymerization
Michihisa Ueda, Tsubasa Aoki, Takayoshi Akiyama, Takayuki Nakamuro, Keitaro Yamashita, Haruaki Yanagisawa, Osamu Nureki, Masahide Kikkawa, Eiichi Nakamura, Takuzo Aida,* Yoshimitsu Itoh*
J. Am. Chem. Soc. 2021, 143, 5121–5126.
Bio-Adhesive Nanoporous Module : Toward Autonomous Gating
Hyuna Jo, Takashi Kitao, Ayumi Kimura, Yoshimitsu Itoh, Takuzo Aida,* Kou Okuro*
Angew. Chem. Int. Ed. 2020, 60, 8932–8937 (selected as “Cover Picture”).
Anomalously Slow Conformational Change Dynamics of Polar Groups Anchored to Hydrophobic Surfaces in Aqueous Media.
Chem. Asian. J. 2020, 15, 3321–3325.
Tengfei Fu, Hao Xing, Eric S. Silver, Yoshimitsu Itoh,* Shuo Chen, Takuya Masuda, Kohei Uosaki, Feihe Huang,* Takuzo Aida*
[DOI: 10.1002/asia.202000742]
Supramolecular Polymerization in Liquid Crystalline Media: Toward Modular Synthesis of Multifunctional Core-Shell Columnar Liquid Crystals.
J. Am. Chem. Soc. 2019, 141, 10033–10038 (selected as “Cover Picture”).
Keiichi Yano, Takahiro Hanebuchi, Xu-Jie Zhang, Yoshimitsu Itoh,* Yoshiaki Uchida, Takuro Sato, Keisuke Matsuura, Fumitaka Kagawa, Fumito Araoka, and Takuzo Aida*
Nematic-to-Columnar Mesophase Transition by In situ Supramolecular Polymerization.
Science 2019, 363, 161–165.
Keiichi Yano, Yoshimitsu Itoh,* Fumito Araoka, Go Watanabe, Takaaki Hikima, and Takuzo Aida *
[DOI: 10.1126/science.aan1019 ]
An Electrochemical Cholesteric Liquid Crystalline Device for Quick and Low-Voltage Color Modulation.
J. Vis. Exp. 2019, 144, e59244.
Shoichi Tokunaga, Mengyan Zeng, Yoshimitsu Itoh,* Fumito Araoka, and Takuzo Aida*
Columnar Liquid Crystalline Assembly of a U-Shaped Molecular Scaffold Stabilized by Covalent or Noncovalent Incorporation of Aromatic Molecules
J. Polym. Sci. A, Polym. Chem. 2019, 57, 342–351.
Yoshiki Shibuya, Yoshimitsu Itoh,* and Takuzo Aida*
A Redox-Responsive Chiral Dopant for Quick Electrochemical Color Modulation of Cholesteric Liquid Crystal
J. Am. Chem. Soc. 2018, 140, 10946–10949 (selected as “Cover Picture”).
Shoichi Tokunaga, Yoshimitsu Itoh,* Hiroyuki Tanaka, Fumito Araoka, and Takuzo Aida*
Enhancement of Superconducting Transition Temperature in FeSe Electric-Double-Layer Transistor with Multivalent
Ionic Liquids
Phys. Rev. Mater. 2018, 2, 031801.
Tomoki Miyakawa, Junichi Shiogai,* Sunao Shimizu, Michio Matsumoto, Yukihiro Ito, Takayuki Harada, Kohei Fujiwara, Tsutomu Nojima, Yoshimitsu Itoh, Takuzo Aida, Yoshihiro Iwasa, and Atsushi Tsukazaki
[DOI: 10.1103/PhysRevMaterials.2.031801 ]
Exceptionally High Electric Double Layer Capacitances of Oligomeric Ionic Liquids
Michio Matsumoto, Sunao Shimizu, Rina Sotoike, Masayoshi Watanabe, Yoshihiro Iwasa,* Yoshimitsu Itoh, and Takuzo Aida*
J. Am. Chem. Soc. 2017, 139, 8784-8787.
Water dynamics: Gliding and trudging
Yoshimitsu Itoh* and Takuzo Aida*
Nature Chem. 2017, 9, 934-936.
Energetics of Baird aromaticity supported by inversion of photoexcited chiral [4n]annulene derivatives
Michihisa Ueda, Kjell Jorner, Young Mo Sung, Tadashi Mori, Qi Xiao, Dongho Kim,* Henrik Ottosson,* Takuzo Aida,* and Yoshimitsu Itoh*
Nature Commun. 2017, 8, 346.
[DOI: 10.1038/s41467-017-00382-1 ]
Jumping Crystals of Pyrene Tweezers: Crystal-to-Crystal Transition Involving π/π-to-CH/π Assembly Mode Switching
Yoshiki Shibuya, Yoshimitsu Itoh,* and Takuzo Aida*
Chem. Asian J. 2017, 12, 811-815.
[DOI: 10.1002/asia.201700083 ]
Electrophoretic Deposition for Cholesteric Liquid-Crystalline Devices with Memory and Modulation of Reflection Colors.
Shoichi Tokunaga, Yoshimitsu Itoh,* Yuya Yaguchi, Hiroyuki Tanaka, Fumito Araoka, Hideo Takezoe, Takuzo Aida*
Adv. Mater. 2016, 28, 4077–4083.
[DOI: 10.1002/adma.201600258 ]
Subnanoscale Hydrophobic Modulation of Salt Bridges in Aqueous Media
S. Chen, Y. Itoh,* T. Masuda, S. Shimizu, J. Zhao, J. Ma, S. Nakamura, K. Okuro, H. Noguchi, K. Uosaki, T. Aida*
Science 2015, 348, 555–559.
[DOI: 10.1126/science.aaa7532 ]
A Rational Strategy for the Realization of Chain-Growth Supramolecular Polymerization
J. Kang, D. Miyajima,* T. Mori, Y. Inoue, Y. Itoh, T. Aida*
Science 2015, 347, 646–651.
[DOI: 10.1126/science.aaa4249 ]
C5-Symmetric Chiral Corannulenes: Desymmetrization of Bowl Inversion Equilibrium via “Intramolecular” Hydrogen-Bonding Network
Jiheong Kang, Daigo Miyajima,* Yoshimitsu Itoh, Tadashi Mori, Hiroki Tanaka, Masahito Yamauchi, Yoshihisa Inoue, Soichiro Harada, and Takuzo Aida*
J. Am. Chem. Soc. 2014, 136, 10640–10644.
Homochiral supramolecular polymerization of bowl-shaped chiral macrocycles in solution
K. Sato, Y. Itoh,* T. Aida*
Chem. Sci. 2014, 5, 136–140.
Theoretical Study on the Regioselectivity of Baeyer–Villiger Reaction of α-Me-, -F-, -CF3-Cyclohexanones
Y.Itoh, M. M. Yamanaka, K. Mikami*
J.Org. Chem. 2013, 78, 146–153.
Columnarly Assembled Liquid Crystalline Peptidic Macrocycles Unidirectionally Orientable over a Large Area by Electric Field.
K. Sato, Y. Itoh,* T. Aida* J. Am. Chem. Soc. 2011, 133, 13767–13769.
Simple Formation of C60 and C60-Ferrocene Conjugated Monolayers Anchored onto Silicon Oxide with Five Carboxylic Acids and Their Transistor Applications.
Y. Itoh,* B. Kim, R. I. Gearba, N. J. Tremblay, R. Pindak, Y. Matsuo, E. Nakamura, C. Nuckolls
Chem. Mater. 2011, 23, 970–975.
Highly enantioselective synthesis of α-(perfluoroalkyl)amines via hydrogenation of enamide precursors in the presence of chiraphos-rhodium catalyst.
K. Mikami,* T. Murase, L. Zhai, Y. Itoh, S. Ito
Tetrahedron Asymmetry 2010, 21, 1158–1161.
Activation of C-F Bonds in Preference to C-I Bonds: Difluoromethylation of Lithium Enolates with Trifluoromethyl Iodide
K. Mikami,* Y. Tomita, Y. Itoh
Angew. Chem. Int. Ed. 2010, 49, 3819–3822.
Photovoltaic Universal Joints: Ball-and-Socket Interfaces in Molecular Photovoltaic Cells
N. J. Tremblay, A. A. Gorodetsky, M. P. Cox, T. Schiros, B. Kim, R. Steiner, Z. Bullard, A. Sattler, W.–Y. So, Y. Itoh, M. F. Toney, H. Ogasawara, A. P. Ramirez, I. Kymissis,* M. L. Steigerwald, C. Nuckolls*
ChemPhysChem 2010, 11, 799–803.
Sequential Perfluoroalkylation and Asymmetric Reduction of Nitriles Triggered with Perfluoroalkyl Titanates:
Catalytic Asymmetric Synthesis of Perfluoroalkyl Amines.
K. Mikami,* T. Murase, L. Zhai, S. Kawauchi, Y. Itoh, S. Ito.
Tetrahedron Lett. 2010, 51, 1371–1373.
Efficient Formation of Ring Structures Utilizing Multisite Activation by Indium Catalysis
. Y.Itoh, H. Tsuji, K. Yamagata, K. Endo, I. Tanaka, M. Nakamura, E. Nakamura*
J. Am. Chem. Soc. 2008, 130, 17161–17167.
Dialkylzinc-accelerated α-Trifluoromethylation of Carbonyl Compounds Catalyzed by Late-transition-metal Complexes
Y. Tomita, Y. Itoh, K. Mikami*
Chem. Lett. 2008, 37, 1080–1081.
Modular Synthesis of Benzo[b]phosphole Derivatives via BuLi-Mediated Cyclization of (o-Alkynylphenyl)phosphin
H. Tsuji,* K. Sato, L. Ilies, Y. Itoh, Y. Sato, E. Nakamura*
Org. Lett. 2008, 10, 2263–2265.
Zncate-Type Enolate for Radical α-Trifluoromethylation
Y. Tomita, Y. Ichikawa, Y. Itoh, K. Kawada, K. Mikami*
Tetrahedron Lett. 2007, 48, 8922–8925.
Indium-Catalyzed Cycloisomerization of ω-Alkynyl-β-ketoesters into Six- to Fifteen-Membered Rings
H. Tsuji, K. Yamagata, Y. Itoh, K. Endo, M. Nakamura, E. Nakamura*
Angew. Chem. Int. Ed. 2007, 46, 8060–8062.
Tandem Reductive Perfluoroalkylation of Esters with Perfluoroalkyl Titanate-Type Reagents
K. Mikami,* T. Murase, Y. Itoh
J. Am. Chem. Soc. 2007, 129, 11686–11687.
Catalytic Asymmetric Synthesis and Anticancer Effects of the Novel Non-Calcemic Analog of Vitamin D, 2α-Fluoro-19-nor-22-oxa-1α,25-dihydroxyvitamin D3 in Metastatic Lung Carcinoma
K. Nakagawa, T. Okano, K. Ozono, S. Kato, N. Kubodera, S. Ohba, Y. Itoh, K. Mikami*
J. Fluorine Chem. 2007, 128, 654–667.
Trifluoromethylation of Metal Enolates and Theoretical Guideline
K. Mikami,* Y. Itoh
In Current Fluoroorganic Chemistry. New Synthetic Directions, Technologies, Materials and Biological Applications; V. A. Soloshonok, K. Mikami, T. Yamazaki, J. T. Welch, J. Honec, Eds.; American Chemical Society: Washington, DC, 2007; p 2–24.
Radical Trifluoromethylation of Ketone Silyl Enol Ethers by Activation with Dialkylzinc
K. Mikami,* Y. Tomita, Y. Ichikawa, K. Amikura, Y. Itoh
Org. Lett. 2006, 8, 4671–4673.
Experimental and Theoretical Studies on Radical Trifluoromethylation of Titanium Ate and Lithium Enolates
Y. Itoh, K. N. Houk, K. Mikami*
J. Org. Chem. 2006, 71, 8918–8925.
Radical Trifluoromethylation of Ketone Li Enolates
Y. Itoh, K. Mikami*
Tetrahedron 2006, 62, 7199–7203.
Nanoflow Microreactor for Dramatic Increase not only in Reactivity but also in Selectivity: Baeyer-Villiger Oxidation by Aqueous Hydrogen Peroxide using Lowest Concentration of a Fluorous Lanthanide Catalyst
K. Mikami,* M. Yamanaka, Md. N. Islam, T. Tonoi, Y. Itoh, M. Shinoda, K. Kudo
J. Fluorine Chem. 2006, 127, 592–596.
Radical Trifluoromethylation of Ti Ate Enolate: Possible Intervention of Transformation of Ti(IV) to Ti(III) for Radical Termination
Y. Itoh, K. Mikami*
J. Fluorine Chem. 2006, 127, 539–544.
Metal Enolates of α-CF3 Ketones: Theoretical Guideline, Direct Generation, and Synthetic Use
K. Mikami,* Y. Itoh
Chem. Rec. 2006, 6, 1–11.
Facile Radical Trifluoromethylation of Lithium Enolates
Y. Itoh, K. Mikami*
Org. Lett. 2005, 7, 4883–4885.
Radical Trifluoromethylation of Titanium Ate Enolate
Y. Itoh, K. Mikami*
Org. Lett. 2005, 7, 649–651.
Fluorinated Synthon: Asymmetric Catalytic Reactions
K. Mikami,* Y. Itoh, M. Yamanaka
In Fluorine-Containing Synthons; V. A. Soloshonok Ed.; American Chemical Society: Washington, DC, 2005; p 356–367.
Direct Generation of Ti-Enolate of α-CF3 Ketone: Theoretical Study and High-Yielding and Diastereoselective Aldol Reaction
Y. Itoh, M. Yamanaka, K. Mikami*
J. Am. Chem. Soc. 2004, 126, 13174–13175.
Hybrid Reagent of Ammonium Hydrogen Fluoride and Scandium Triflate: Highly Efficient Catalyst for Ring-Opening Fluorination of 2,3-Epoxyalcohols
Y. Itoh, S. Jang, S. Ohba, K. Mikami*
Chem. Lett. 2004, 33, 776–777.
Nanoflow System for Perfect Regiocontrol in the Baeyer-Villiger Oxidation by Aqueous Hydrogen Peroxide using Lowest Concentration of a Fluorous Lanthanide Catalyst
K. Mikami,* Md. N. Islam, M. Yamanaka, Y. Itoh, M. Shinoda, K. Kudo
Tetrahedron Lett. 2004, 45, 3681–3683.
Fluorinated Carbonyl and Olefinic Compounds: Basic Character and Asymmetric Catalytic Reactions
K. Mikami,* Y. Itoh, M. Yamanaka
Chem. Rev. 2004, 104, 1–16.
Dipole Interaction-Controlled Stereoselectivity in Aldol Reaction of α-CF3 Enolate with Fluoral.
Y. Itoh, M. Yamanaka, K. Mikami*
Org. Lett. 2003, 5, 4807–4809.
Complete Reversal in Regioselectivity in the Baeyer-Villiger Reaction of an α-CF3-Ketone and Theoretical Rationale for Axial Orientation of Sterically Demanding CF3 group at the Transition State
Y. Itoh, M. Yamanaka, K. Mikami*
Org. Lett. 2003, 5, 4803–4806.
Organic Fluorine Compounds with Full of Character: Their (Catalytic) Asymmetric Synthesis (2).
K. Mikami,* Y. Itoh, M. Yamanaka
Fine Chemical 2003, 32 (2), 11–20.
Organic Fluorine Compounds with Full of Character: Their (Catalytic) Asymmetric Synthesis (1).
K. Mikami,* Y. Itoh, M. Yamanaka
Fine Chemical 2003, 32 (1), 35–50.
Dr. Yoshimitsu ITOH
Associate Professor Chemistry and Biotechnology, School of Engineering
The University of Tokyo
itoh＠macro.t.u-tokyo.ac.jp
