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査読付き論文

Jumpei Morimoto,* Yasuhiro Fukuda, and Shinsuke Sando*
"Solid-Phase Synthesis of β-Peptoids with Chiral Backbone Substituents Using Reductive Amination"
Org. Lett. 2017, 19, 5912-5915.

Ryosuke Ueki,* Saki Atsuta, Ayaka Ueki, and Shinsuke Sando*
"Nongenetic Reprogramming of the Ligand Specificity of Growth Factor Receptors by Bispecific DNA Aptamers"
J. Am. Chem. Soc. 2017, 139, 6554-6557.

Tatsuya Nishihara, Yutaka Kameyama, Hiroshi Nonaka, Yoichi Takakusagi, Fuminori Hyodo, Kazuhiro Ichikawa, and Shinsuke Sando*
"A Strategy to Design Hyperpolarized ¹³C Magnetic Resonance Probes Using [1-¹³C]α-Amino Acid as a Scaffold Structure"
Chem. Asian. J. 2017, 12, 949-953.

Hiroshi Nonaka,* Masashi Hirano, Yuki Imakura, Yoichi Takakusagi, Kazuhiro Ichikawa, and Shinsuke Sando*
"Design of a 15N Molecular Unit to Achieve Long Retention of Hyperpolarized Spin State"
Sci. Rep. 2017, 7, 40104.

Tatsuya Nishihara,# Hikari A. I. Yoshihara,# Hiroshi Nonaka, Yoichi Takakusagi, Fuminori Hyodo, Kazuhiro Ichikawa, Emine Can, Jessica A. M. Bastiaansen, Yuhei Takado, Arnaud Comment,* and Shinsuke Sando*
# These authors contributed equally to this work.
"Direct Monitoring of γ-Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized 13C-Labeled Molecular Probe"
Angew. Chem. Int. Ed. 2016, 55, 10626-10629.


Akira Tsuchiya, Siti N. Hashim, Shoko Ise, Takafumi Furuhata, Kiyohiko Kawai, Rie Wakabayashi, Masahiro Goto, Noriho Kamiya, and Shinsuke Sando*
"BODIPY-labeled Fluorescent Aptamer Sensors for Turn-on Sensing of Interferon-gamma and Adenine Compounds on Cells"
Anal. Sci. 2016, 32, 543-547.
Selected as Hot Article



Ryunosuke Hata, Hiroshi Nonaka, Yoichi Takakusagi, Kazuhiro Ichikawa, and Shinsuke Sando*
"Design of a Hyperpolarized Molecular Probe for Detection of Aminopeptidase N Activity"
Angew. Chem. Int. Ed. 2016, 55, 1765-1768.



Ryosuke Ueki, Ayaka Ueki, Naoto Kanda, and Shinsuke Sando*
"Oligonucleotide-based Mimetics of Hepatocyte Growth Factor"
Angew. Chem. Int. Ed. 2016, 55, 579-582.
Selected as Hot Paper



Hisatsugu Yamada, Tetsuro Kameda, Yu Kimura, Hirohiko Imai, Tetsuya Matsuda, Shinsuke Sando, Akio Toshimitsu, Yasuhiro Aoyama*, and Teruyuki Kondo*
"13C/15N-Enriched L-Dopa as a Triple-Resonance NMR Probe to Monitor Neurotransmitter Dopamine in the Brain and Liver Extracts of Mice"
ChemistryOpen 2016, 5, 125-128.


Siti Norulhuda Hashim, Akira Tsuchiya, Noriho Kamiya, and Shinsuke Sando*
"A Single Fluorophore-labeled Aptamer Sensor for the Detection of Interferon Gamma"
Chem. Lett., 2015, 44, 1670-1672.

Ryunosuke Hata, Hiroshi Nonaka, Yoichi Takakusagi, Kazuhiro Ichikawa, and Shinsuke Sando*
"Design of a hyperpolarized 15N NMR probe that induces a large chemical-shift change upon binding of calcium ion."
Chem. Commun. 2015, 51, 12290-12292.

Hisatsugu Yamada, Yoshinori Hasegawa, Hirohiko Imai, Yuki Takayama, Fuminori Sugihara, Tetsuya Matsuda, Hidehito Tochio, Masahiro Shirakawa, Shinsuke Sando, Yu Kimura, Akio Toshimitsu, Yasuhiro Aoyama*, and Teruyuki Kondo*
"Magnetic Resonance Imaging of Tumor with a Self-Traceable Phosphorylcholine Polymer."
J. Am. Chem. Soc. 2015, 137, 799-806.

Hiroshi Nonaka, Qi An, Fuminori Sugihara, Tomohiro Doura, Akira Tsuchiya, Yoshichika Yoshioka, and Shinsuke Sando*
"Phenylboronic acid-based (19)F MRI probe for the detection and imaging of hydrogen peroxide utilizing its large chemical-shift change."
Anal. Sci. 2015, 31, 331-335.

Ryosuke Ueki, and Shinsuke Sando*
"A DNA aptamer to c-Met inhibits cancer cell migration."
Chem. Commun. 2014, 50, 13131-13134.

Tatsuya Nishihara, Hiroshi Nonaka, and Shinsuke Sando*
"Design of Triple-resonance NMR Reporter Assay."
Chem. Lett. 2014, 43, 1873-1875.

Tomohiro Doura, Ryunosuke Hata, Hiroshi Nonaka, Fuminori Sugihara, Yoshichika Yoshioka, and Shinsuke Sando*
"An adhesive 19F MRI chemical probe allows signal off-to-on-type molecular sensing in a biological environment."
Chem. Commun. 2013, 49, 11421-11423.

Hiroshi Nonaka, Ryunosuke Hata, Tomohiro Doura, Tatsuya Nishihara, Keiko Kumagai, Mai Akakabe, Masashi Tsuda, Kazuhiro Ichikawa, and Shinsuke Sando*
"A platform for designing hyperpolarized magnetic resonance chemical probes."
Nat. Commun. 2013, 4, Article Number: 2411, doi: 10.1038/ncomms3411.

Takeshi Tokunaga, Kohei Kuwahata, Shinsuke Sando*
"Systematic Exploration of Lipophilic Tags That Allow Efficient Anchoring of Aptamers to Live Cell Surfaces."
Chem. Lett. 2013, 42, 127-129.

Tomohiro Doura, Ryunosuke Hata, Hiroshi Nonaka, Kazuhiro Ichikawa, and Shinsuke Sando*
"Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long-Lived Hyperpolarization Unit."
Angew. Chem. Int. Ed. 2012, 51, 10114-10117.

Ryosuke Ueki, Koya Yamaguchi, Hiroshi Nonaka, and Shinsuke Sando*
"1H-NMR Probe for In Situ Monitoring of Dopamine Metabolism and Its Application to Inhibitor Screening."
J. Am. Chem. Soc. 2012, 134, 12398-12401.

Takeshi Tokunaga, Shigeyuki Namiki, Katsuhiro Yamada, Takahiro Imaishi, Hiroshi Nonaka, Kenzo Hirose, and Shinsuke Sando*
"Cell Surface-Anchored Fluorescent Aptamer Sensor Enables Imaging of Chemical Transmitter Dynamics."
J. Am. Chem. Soc. 2012, 134, 9561-9564.

Hisatsugu Yamada, Keigo Mizusawa, Ryuji Igarashi, Hidehito Tochio, Masahiro Shirakawa, Yasuhiko Tabata, Yu Kimura, Teruyuki Kondo, Yasuhiro Aoyama,* and Shinsuke Sando*
"Substrate/Product-Targeted NMR Monitoring of Pyrimidine Catabolism and Its Inhibition by a Clinical Drug."
ACS Chem. Biol. 2012, 7, 535-542.

Tatsuya Nishihara, Hiroshi Nonaka, Tatsuya Naganuma, Kazuhiro Ichikawa, Shinsuke Sando*
"Mouse Lactate Dehydrogenase X: A Promising Magnetic Resonance Reporter Protein Using Hyperpolarized Pyruvic Acid Derivative Y."
Chem. Sci. 2012, 3, 800-806.

Tomohiro Doura, Hiroshi Nonaka, Shinsuke Sando*
"Atom Arrangement Strategy for Designing Turn-On 1H Magnetic Resonance Probe: Dual Activatable Probe for Multimodal Detection of Hypochlorite."
Chem. Commun. 2012, 48, 1565-1567.

Atsushi Ogawa,* Masayoshi Hayami, Shinsuke Sando,* and Yasuhiro Aoyama
"A Concept for Selection of Codon-Suppressor tRNAs Based on Read-Through Ribosome Display in an In Vitro Compartmentalized Cell-Free Translation System."
J. Nucleic Acids 2012, Article ID 538129.

Koya Yamaguchi, Ryosuke Ueki, Hiroshi Nonaka, Fuminori Sugihara, Tetsuya Matsuda, Shinsuke Sando*
"Design of Chemical Shift-Switching 19F Magnetic Resonance Imaging Probe for Specific Detection of Human Monoamine Oxidase A"
J. Am. Chem. Soc. 2011, 133, 14208-14211.

Koya Yamaguchi, Ryosuke Ueki, Hisatsugu Yamada, Yasuhiro Aoyama, Hiroshi Nonaka, Shinsuke Sando*
"In situ analysis of [8-13C-7-15N]-double-labelled theophylline by triple resonance NMR technique"
Anal. Methods 2011, 3, 1664-1666.

Shinsuke Sando*
"Design of Functional Nucleic Acid Systems for Biomolecular Analysis"
Bull. Chem. Soc. Jpn. 2011, 84, 133-140.
Award Account for The Chemical Society of Japan Award for Young Chemists

Tomohiro Doura, An Qi, Fuminori Sugihara, Tetsuya Matsuda, Shinsuke Sando*
"p-Aminophenyl Alkyl Ether-based 19F MRI Probe for Specific Detection and Imaging of Hypochlorite Ion"
Chem. Lett. 2011, 12, 1357-1359.

Tomohiro Tsuji, Katsuya Gonda, Yasuhiro Aoyama,* Takeshi Tokunaga, and Shinsuke Sando*
"Inhibitor-Substituted BODIPY as a Turn-on Fluorescence Probe for Enzymes"
Chem. Lett. 2011, 40, 1275-1277.

Keigo Mizusawa, Ryuji Igarashi, Kosei Uehira, Yoshimasa Takafuji, Yasuhiko Tabata, Hidehito Tochio, Masahiro Shirakawa,* Shinsuke Sando,* Yasuhiro Aoyama*
"Turn-On Detection of Targeted Biochemical Reactions by Triple Resonance NMR Analysis Using Isotope-labeled Probe"
Chem. Lett. 2010, 39, 926-928.
Selected as Editor's Choice
Chika Furutani, Kazuki Shinomiya, Yasuhiro Aoyama,* Katsuhiro Yamada, and Shinsuke Sando*
"Modular Blue Fluorescent RNA Sensors for Label-Free Detection of Target Molecules"
Mol. Biosystems 2010, 6, 1569-1571.
Selected in Emerging Investigators Issue

Hiroki Masu, Atsushi Narita, Takeshi Tokunaga, Masayoshi Ohashi, Yasuhiro Aoyama,* and Shinsuke Sando*
"An activatable siRNA probe: trigger-RNA-dependent activation of RNAi function"
Angew. Chem. Int. Ed. 2009, 48, 9481-9483.
Selected as Hot Paper

Keigo Mizusawa, Kenji Abe, Shinsuke Sando,* and Yasuhiro Aoyama*
"Synthesis of Puromycin Derivatives with Backbone-Elongated Substrates and Associated Translation Inhibitory Activities"
Shinsuke Sando,* Atsushi Narita, Masayoshi Hayami and Yasuhiro Aoyama*
"Transcription Monitoring Using Fused RNA with a Dye-Binding Light-Up Aptamer as a Tag: A Blue Fluorescent RNA"
Chem. Commun. 2008, 3858-3860.
Selected as Hot Article and Inside Cover

Shinsuke Sando,* Hiroki Masu, Chika Furutani and Yasuhiro Aoyama*
"Enzymatic N-methylaminoacylation of tRNA using chemically misacylated AMP as a substrate"
Org. Biomol. Chem. 2008, 6, 2666-2668.

Shinsuke Sando,* Atsushi Narita, Masayoshi Hayami, and Yasuhiro Aoyama*
"Tuning the Hoechst Dye into Color-changing Fluorescent pH Indicator in an Acidic Range"
Chem. Lett. 2008, 37, 246-247.
Shinsuke Sando,* Atsushi Narita, Yasuhiro Aoyama*
"Light-Up Hoechst-DNA Aptamer Pair: Generation of an Aptamer-Selective Fluorophore from a Conventional DNA-Staining Dye"
ChemBioChem 2007, 8, 1795-1803.

Shinsuke Sando,* Kenji Abe, Nobuhiko Sato, Toshihiro Shibata, Keigo Mizusawa, and Yasuhiro Aoyama*
"Unexpected Preference of the E. coli Translation System for Ester-Bond During Incorporation of Backbone-Elongated Substrates"
J. Am. Chem. Soc. 2007, 129, 6180-6186.

Atsushi Narita, Kazumasa Ogawa, Shinsuke Sando,* Yasuhiro Aoyama*
"Cis-regulatory hairpin-shaped mRNA encoding a reporter protein: catalytic sensing of nucleic acid sequence at single nucleotide resolution"
Nature Protocols 2007, 2, 1105-1116.

Shinsuke Sando,* Atsushi Ogawa, Teruyuki Nishi, Masayoshi Hayami, Yasuhiro Aoyama*
"In Vitro Selection of RNA Aptamer Against Escherichia Coli Release Factor 1"
Bioorg. Med. Chem. Lett. 2007, 17, 1216-1220.