研究成果（宮川信一）

  1. 研究成果
  2. 計画研究A03 - 宮川信一

  1. 037

    Tanaka K, Matsumaru D, Suzuki K, Yamada G, Miyagawa S.

    "The role of p63 on embryonic genital organ outgrowth in mice."

    Dev Growth Differ 2023 in press.

  2. 036

    Horie Y, Yamagishi T, Yamamoto J, Suzuki M, Onishi Y, Chiba T, Miyagawa S, Lange A, Tyler CR, Okamura H, Iguchi T.

    "Adverse effects of thyroid-hormone-disrupting chemicals 6-propyl-2-thiouracil and tetrabromobisphenol A on Japanese medaka (Oryzias latipes)."

    Comp Biochem Physiol C Toxicol Pharmacol 2023 263: 109502.

  3. 035

    Akashi H, Kubota M, Yamamoto H, Miyaoku K, Yamagishi G, Miyagawa S.

    "Chronology of embryonic and gonadal development in the Reeves' turtle, Mauremys Reevesii."

    Sci Rep 2022 12: 11619.

  4. 034

    Yamagishi G, Park MK, Miyagawa S.

    "Evolution of g6pc1 paralogs in sarcopterygian lineages: multiple origins and functional divergence among ectotherms."

    Zool Sci 2022 39: 419–430.

  5. 033

    Myosho T, Ishibashi A, Fujimoto S, Miyagawa S, Iguchi T, Kobayashi T.

    "Pre-self-feeding medaka fry provides a suitable screening system for in vivo assessment of thyroid hormone-disrupting potential."

    Environ Sci Technol 2022 56: 6479–6490.

  6. 032

    Horie Y, Okamoto K, Yamamoto M, Takahashi C, Sato T, Miyagawa S, Okamura H, Iguchi T.

    "Effect of thyroid hormone-disrupting chemicals on swim bladder inflation and thyroid hormone-related gene expression in Japanese medaka and zebrafish."

    J Appl Toxicol 2022 42: 1385–1395.

  7. 031

    Toyota K, Watanabe H, Hirano M, Abe R, Miyakawa H, Song Y, Sato T, Miyagawa S, Tollefsen KE, Tatarazako N, Iguchi T.

    "Juvenile hormone synthesis and signaling disruption triggering male offspring induction and population decline in cladocerans: review and adverse outcome pathway development."

    Aquat Toxicol 2022 243: 106058.

  8. 030

    Kajioka S, Suzuki K, Matsushita S, Hino S, Sato T, Takada S, Isono K, Takeo T, Kajimoto M, Nakagata N, Nakao M, Suyama M, DeFalco T, Miyagawa S, Yamada G.

    "Sexual fate of murine external genitalia development: conserved transcriptional competency for male-biased genes in both sexes."

    Proc Natl Acad Sci USA 2021 118: e2024067118.

  9. 029

    Toyota K, Arai Y, Miyagawa S, Kogo Y, Takeuchi K.

    "Novel validating indices to indicate sexual differences in the horsehair crab Erimacrus isenbeckii (Brandt, 1848)."

    Aquat Anim AA2021: 1–8.

  10. 028

    Miyaoku K, Ogino Y, Lange A, Ono A, Kobayashi T, Ihara M, Tanaka H, Toyota K, Akashi H, Yamagishi G, Sato T, Tyler CR, Iguchi T, Miyagawa S.

    "Characterization of G protein-coupled estrogen receptors in Japanese medaka, Oryzias latipes."

    J Appl Toxicol 2021 41: 1390–1399.

  11. 027

    Iguchi T, Sato T, Nakajima T, Miyagawa S, Takasugi N.

    "New frontiers of developmental endocrinology opened by researchers connecting irreversible effects of sex hormones on developing organs."

    Differentiation 2021 18: 4–23.

  12. 026

    Toyota K, Masuda S, Sugita S, Miyaoku K, Yamagishi G, Akashi H, Miyagawa S.

    "Estrogen receptor 1 (ESR1) agonist induces ovarian differentiation and aberrant Müllerian duct development in Chinese soft-shelled turtle, Pelodiscus sinensis."

    Zool Stud 2020 59: 54.

  13. 025

    Parsons A, Lange A, Kudoh T, Hutchinson T, Miyagawa S, Iguchi T, Tyler CR.

    "Expression dynamics of genes in the hypothalamic-pituitary-thyroid (HPT) cascade and their responses to 3,5,3’-tri-iodothyronine highlights potential vulnerability to thyroid-disrupting chemicals in zebrafish (Danio rerio) embryo-larvae."

    Aquat Toxicol 2020 225: 105547.

  14. 024

    Terauchi KJ, Miyagawa S, Iguchi T, Sato T.

    "Hedgehog signaling regulates the basement membrane remodeling during folliculogenesis in the neonatal mouse ovary."

    Cell Tissue Res 2020 381: 555–567.

  15. 023

    Lange A, Paris J, Gharbi K, Cezard T, Miyagawa S, Iguchi T, Studholme D, Tyler CR.

    "A newly developed genetic sex marker and its application to understanding chemically induced feminisation in roach (Rutilus rutilus)."

    Mol Ecol Resour 2020 20: 1007–1022.

  16. 022

    Kajioka D, Suzuki K, Nakada S, Matsushita S, Miyagawa S, Takeo T, Nakagata N, Yamada G.

    "Bmp4 is an essential growth factor for the initiation of genital tubercle (GT) outgrowth."

    Congenit Anom (Kyoto) 2020 60: 15–21.

  17. 021

    Hyuga T, Alcantara M, Kajioka D, Haraguchi R, Suzuki K, Miyagawa S, Kojima Y, Hayashi Y, Yamada G.

    "Hedgehog signaling for urogenital organogenesis and prostate cancer: an implication for the epithelial-mesenchyme interaction (EMI)."

    Int J Mol Sci 2019 21: 58.

  18. 020

    Hyuga T, Suzuki K, Acebedo AR, Hashimoto D, Kajimoto M, Miyagawa S, Enmi J, Yoshioka Y, Yamada G.

    "Regulatory roles of epithelial-mesenchymal interaction (EMI) during early and androgen dependent external genitalia development."

    Differentiation 2019 110: 29–35.

  19. 019

    Hirano Y, Suzuki K, Iguchi T, Yamada G, Miyagawa S.

    "The role of Fgf signaling on epithelial cell differentiation in mouse vagina."

    In Vivo 2019 33: 1499–1505.

  20. 018

    Oikawa S, Kobayashi S, Miyagawa S, Iguchi T, Sato T.

    "Diethylstilbestrol alters the expression of activins in the neonatal mouse ovary in vitro."

    In Vivo 2019 33: 1095–1102.

  21. 017

    Saeki H, Miyagawa S, Hirano Y, Kajimoto M, Yamada G.

    "Altered expression of sex hormone receptor genes in mouse external genitalia by hormonal modulations."

    J Wakayama Med Soc 2019 70: 2.

  22. 016

    荻野由紀子・宮川信一.

    「魚類と特性を活かした遺伝子研究」

    『遺伝子医学』 2019 9: 160–166.

  23. 015

    宮川信一.

    「温度で決まる動物のオスとメスの研究」

    『理大科学フォーラム』 2019 36: 36–41.

  24. 014

    Parsons A, Lange A, Hutchinson TH, Miyagawa S, Iguchi T, Kudoh T, Tyler CR.

    "Molecular mechanisms and tissue targets of brominated flame retardants, BDE-47 and TBBPA, in embryo-larval life stages of zebrafish (Danio rerio)."

    Aquat Toxicol 2019 209: 99–112.

  25. 013

    Acebedo AR, Suzuki K, Hino S, Alcantara, MC, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein, RS, Yamada G.

    "Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice."

    Commun Biol 2019 8: 95.

  26. 012

    Kajioka D, Suzuki K, Nakada S, Matsushita S, Miyagawa S, Takeo T, Nakagata N, Yamada G.

    "Bmp4 is an essential growth factor for the initiation of genital tubercle (GT) outgrowth."

    Congenit Anom (Kyoto) 2020 60: 15–21.

  27. 011

    Kojima Y, Koguchi T, Mizuno K, Sato Y, Hoshi S, Hata J, Nishio H, Hashimoto D, Matsushita S, Suzuki K, Miyagawa S, Hui CC, Tanikawa C, Murakami Y, Yamada G, Hayashi Y, Matsuda K.

    "Single nucleotide polymorphisms of HAAO and IRX 6 genes as risk factors for hypospadias."

    J Urol 2019 201: 386–392.

  28. 010

    Miyagawa S, Yatsu R, Iguchi T.

    "Environmental control on sex differentiation in reptiles."

    In: Reproductive and Developmental Strategies: The Continuity of Life 2018 pp. 367–390.

  29. 009

    Ogino Y, Tohyama S, Kohno S, Toyota K, Yamada G, Yatsu R, Kobayashi T, Tatarazako N, Sato T, Matsubara H, Lange A, Tyler CR, Katsu Y, Iguchi T, Miyagawa S.

    "Functional distinctions associated with the diversity of sex steroid hormone receptors ESR and AR."

    J Steroid Biochem Mol Biol 2018 184: 38–46.

  30. 008

    Matsushita S, Suzuki K, Murashima A, Kajioka D, Acebedo AR, Miyagawa S, Haraguchi R, Ogino Y, Yamada G.

    "Regulation of masculinization: androgen signalling for external genitalia development."

    Nat Rev Urol 2018 15: 358–368.

  31. 007

    Fujimoto N, Kitamura S, Uramaru N, Miyagawa S, Iguchi T.

    "Identification of hepatic thyroid hormone-responsive genes in neonatal rats: potential targets for thyroid hormone-disrupting chemicals."

    Toxicol Lett 2018 286: 48–53.

  32. 006

    Kohno S, Katsu Y, Cipoletti N, Wang LC, Jorgenson ZG, Miyagawa S, Schoenfuss HL.

    "Divergent responsiveness of two isoforms of the estrogen receptor to mixtures of contaminants of emerging concern in four vertebrates."

    J Appl Toxicol 2018 38: 705–713.

  33. 005

    Miyakawa H, Watanabe M, Araki M, Ogino Y, Miyagawa S, Iguchi T.

    "Juvenile hormone-independent function of Krüppel homolog 1 in early development of water flea Daphnia pulex."

    Insect Biochem Mol Biol 2017 93: 12–18.

  34. 004

    Tohyama S, Ogino Y, Lange A, Myosho T, Kobayashi T, Hirano Y, Yamada G, Sato T, Tatarazako N, Tyler CR, Iguchi T, Miyagawa S.

    "Establishment of estrogen receptor 1 (ESR1)-knockout medaka: ESR1 is dispensable for sexual development and reproduction in medaka, Oryzias latipes."

    Dev Growth Diff 2017 59: 552–561.

  35. 003

    Matsubara K, Nakamura N, Sanoh S, Ohta S, Kitamura S, Uramaru N, Miyagawa S, Iguchi T, Fujimoto N.

    "Altered expression of Olr59, Ethe1, and Slc10a2 genes in the liver of F344 rats by neonatal thyroid hormone disruption."

    J Appl Toxicol 2017 37:1030–1035.

  36. 002

    Lange A, Corcorana J, Miyagawa S, Iguchi T, Winter MJ, Tyler CR.

    "Development of a common carp (Cyprinus carpio) pregnane X receptor (cPXR) transactivation reporter assay and its activation by azole fungicides and pharmaceutical chemicals."

    Toxicol In Vitro 2017 41: 114–122.

  37. 001

    井口泰泉・佐藤友美・遠山早紀・荻野由紀子・宮川信一.

    「内分泌かく乱物質問題の現状と環境依存性性分化」

    『腎泌尿器学会誌』 2018 26: 7–9.