研究成果（的場章悟）

  1. 研究成果
  2. 公募研究A01 - 的場章悟

  1. 019

    Akter MS, Hada M, Shikata D, Watanabe G, Ogura A, Matoba S.

    "CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice."

    Sci Rep 2021 11: 15438.

  2. 018

    Morimoto H, Ogonuki N, Kanatsu-Shinohara M, Matoba S, Ogura A, Shinohara T.

    "Spermatogonial stem cell transplantation into nonablated mouse recipient testes."

    Stem Cell Rep 2021 16: 1832–1844.

  3. 017

    Kobayashi Y, Tomizawa SI, Ono M, Kuroha K, Minamizawa K, Natsume K, Dizdarević S, Dočkal I, Tanaka H, Kawagoe T, Seki M, Suzuki Y, Ogonuki N, Inoue K, Matoba S, Anastassiadis K, Mizuki N, Ogura A, Ohbo K.

    "Tsga8 is required for spermatid morphogenesis and male fertility in mice."

    Development 2021 148: dev196212.

  4. 016

    Ogura A, Matoba S, Inoue K.

    "Epigenetic abnormalities associated with somatic cell nuclear transfer."

    Reproduction 2021 162: F45–F58.

  5. 015

    Hasegawa A, Mochida K, Matoba S, Inoue K, Hama D, Kadota M, Hiraiwa N, Yoshiki A, Ogura A.

    "Development of assisted reproductive technologies for Mus spretus."

    Biol Reprod 2021 104: 234–243.

  6. 014

    Miura K, Matoba S, Hirose M, Ogura A.

    "Generation of chimeric mice with spermatozoa fully derived from embryonic stem cells using a triple-target CRISPR method for Nanos3."

    Biol Reprod 2021 104: 223–233.

  7. 013

    Kazuki Y, Gao FJ, Li Y, Moyer AJ, Devenney B, Hiramatsu K, Miyagawa-Tomita S, Abe S, Kazuki K, Kajitani N, Uno N, Takehara S, Takiguchi M, Yamakawa M, Hasegawa A, Shimizu R, Matsukura S, Noda N, Ogonuki N, Inoue K, Matoba S, Ogura A, Florea LD, Savonenko A, Xiao M, Wu D, Batista DA, Yang J, Qiu Z, Singh N, Richtsmeier JT, Takeuchi T, Oshimura M, Reeves RH.

    "A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21."

    Elife 2020 9: e56223.

  8. 012

    Inoue K, Ogonuki N, Kamimura S, Inoue H, Matoba S, Hirose M, Honda A, Miura K, Hada M, Hasegawa A, Watanabe N, Dodo Y, Mochida K, Ogura A.

    "Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas."

    Nat Commun 2020 11: 2150.

  9. 011

    Mizuno-Iijima S, Ayabe S, Kato K, Matoba S, Ikeda Y, Dinh TTH, Le HT, Suzuki H, Nakashima K, Hasegawa Y, Hamada Y, Tanimoto Y, Daitoku Y, Iki N, Ishida M, Ibrahim EAE, Nakashiba T, Hamada M, Murata K, Miwa Y, Okada-Iwabu M, Iwabu M, Yagami KI, Ogura A, Obata Y, Takahashi S, Mizuno S, Yoshiki A, Sugiyama F.

    "Efficient production of large deletion and gene fragment knock-in mice mediated by genome editing with Cas9-mouse Cdt1 in mouse zygotes."

    Methods 2020 in press.

  10. 010

    Kanatsu-Shinohara M, Ogonuki N, Matoba S, Ogura A, Shinohara T.

    "Autologous transplantation of spermatogonial stem cells restores fertility in congenitally infertile mice."

    Proc Natl Acad Sci U S A 2020 117: 7837–7844.

  11. 009

    Hirose M, Honda A, Fulka H, Tamura-Nakano M, Matoba S, Tomishima T, Mochida K, Hasegawa A, Nagashima K, Inoue K, Ohtsuka M, Baba T, Yanagimachi R, Ogura A.

    "Acrosin is essential for sperm penetration through the zona pellucida in hamsters."

    Proc Natl Acad Sci U S A 2020 117: 2513–2518.

  12. 008

    Matoba S, Nakamuta S, Miura K, Hirose M, Shiura H, Kohda T, Nakamuta N, Ogura A.

    "Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice."

    Proc Natl Acad Sci USA 2019 doi: 10.1073/pnas.

    プレスリリース 胎盤・胎児の発生に重要なアミノ酸トランスポーターを同定

  13. 007

    Inoue K, Matoba S, Ogura A.

    "Somatic cell nuclear transfer in mice: basic protocol and its modification for correcting X chromosome inactivation status."

    Methods Mol Biol 2018 1861: 55–65.

  14. 006

    Hirose M, Hada M, Kamimura S, Matoba S, Honda A, Motomura K, Ogonuki N, Shawki HH, Inoue K, Takahashi S, Ogura A.

    "Aberrant imprinting in mouse trophoblast stem cells established from somatic cell nuclear transfer-derived embryos."

    Epigenetics 2018 13: 693–703.

  15. 005

    Matoba S, Zhang Y.

    "Somatic cell nuclear transfer reprogramming: mechanisms and applications."(review)."

    Cell Stem Cell 2018 23: 471–485.

  16. 004

    Matoba S, Wang H, Jiang L, Lu F, Iwabuchi KA, Wu X, Inoue K, Yang L, Press W, Lee JT, Ogura A, Shen L, Zhang Y.

    "Loss of H3K27me3 imprinting in somatic cell nuclear transfer embryos disrupts post-implantation development."

    Cell Stem Cell 2018 23: 343–354.

    プレスリリース クローン胚の新たなエピゲノム異常を発見：ヒストン修飾によるゲノムインプリンティングが破綻

  17. 003

    Djekidel MN, Inoue A, Matoba S, Suzuki T, Zhang C, Lu F, Jiang L, Zhang Y.

    "Reprogramming of chromatin accessibility in somatic cell nuclear transfer is DNA replication independent."

    Cell Rep 2018 23: 1939–1947.

  18. 002

    Miura K, Matoba S, Ogonuki N, Namiki T, Ito J, Kashiwazaki N, Ogura A.

    "Application of auxin-inducible degron technology to mouse oocyte activation with PLCζ."

    J Reprod Dev 2018 64: 319–326.

  19. 001

    Watanabe S, Kanatsu-Shinohara M, Ogonuki N, Matoba S, Ogura A, Shinohara T.

    "In vivo genetic manipulation of spermatogonial stem cells and their microenvironment by adeno-associated viruses."

    Stem Cell Reports 2018 10: 1551–1564.