Research

Original Papers, Reviews & Books



2022


Original Papers

Takahashi, K., Jia, H., Takahashi, S. and Kato, H. Comprehensive miRNA and DNA microarray analysis reveal the response of hepatic miR-203 and its target gene to protein malnutrition in rats. Genes, 13, 75 (2022)

Miyoshi, M., Saito, K., Jia, H. and Kato, H. Maternal protein restriction and post-weaning high-fat feeding alter plasma amino acid profiles and hepatic gene expression in mice offspring. Foods, 11, 753 (2022)

Yang, Y., Jia, H., Furukawa, K., Li, X., Hasebe, Y. and Kato, H. Dietary eggshell membrane powder improves survival rate and ameliorates gut dysbiosis in interleukin-10 knockout mice. Front. Nutr. in press (2022)

Takahashi, S., Saito, K., Li, X., Jia, H. and Kato, H. iTRAQ-based quantitative proteomics reveals the energy metabolism alterations induced by chlorogenic acid in HepG2 cells. Nutrients, 14, 1676 (2022)

2021

Original Papers

Miyoshi, M., Imakado, Y., Otani, L., Kaji, M., Aanzai, Y., Sugimoto, N., Murakami, T., Fukuoka, M., Hohjoh, H., Jia, H. and Kato, H. Maternal protein restriction induces renal AT2R promoter hypomethylation in salt-sensitive, hypertensive rats. Food Sci. Nutr.9, 1452-1459 (2021)

Lyu, W., Jia, H., Deng, C., Yamada, S. and Kato, H. Zeolite-containing mixture alleviates microbial dysbiosis in dextran sodium sulfate induced colitis in mice. Food Sci. Nutr. 9, 772-780 (2021)

2020

Original Papers

Furukawa, K., Igarashi, M., Jia, H., Nogawa, S., Kawafune, K., Hachiya, T., Takahashi, S., Saito, K. and Kato, H. A Genome-wide association study identifies the association between the 12q24 locus and black tea consumption in Japanese populations. Nutrients, 12, 3182 (2020)

Hamano, M., Tomonaga, S., Osaki, Y., Oda, H., Kato, H. and Furuya, S. Transcriptional activation of Chac1 and other Atf4-target genes induced by extracellular L-serine depletion is negated with glycine consumption in Hepa1-6 hepatocarcinoma cells. Nutrients.12, 3018 (2020)

Otani, L., Nishi, H., Koyama, A., Akasaka, Y., Taguchi, Y., Toyoshima, Y., Yamanaka, D., Hakuno, F., Jia, H., Takahashi, S.-I. and Kato, H. Low-arginine and low-protein diets induce hepatic lipid accumulation through different mechanisms in growing rats. Nutr. Metab.17, 60 (2020)

Toyoshima, Y., Nakamura, K., Tokita, R., Teramoto, N., Sugihara, H., Kato, H., Yamanouchi, K, and Minami, S. Disruption of insulin receptor substrate-2 impairs growth but not insulin function in rats. J. Biol. Chem. 295, 11914-11927 (2020)

Kawafune, K., Hachiya, T., Nogawa, S., Takahashi, S., Jia, H., Saito, K. and Kato, H. Strong association between the 12q24 locus and sweet taste preference in the Japanese population revealed by genome-wide meta-analysis. J. Human, Genet. 65, 939–947 (2020)

Ramli, N. S., Jia, H., Sekine, A., Lyu, W., Furukawa, K., Saito, K., Hasebe, Y. and Kato, H. Eggshell membrane powder lowers plasma triglyceride and liver total cholesterol by modulating gut microbiota and accelerating lipid metabolism in high‐fat diet‐fed mice. Food Sci. Nutr. 8, 2512-2523 (2020)

Toyoshima, Y., Yoshizawa, F., Tokita, R., Taguchi, Y., Takahashi, S.-I., Kato, H. and Minami, S. A translation repressor, 4E-BP1, regulates the triglyceride level in rat liver during protein deprivation. Am. J. Physiol. Endocrinol. Metab. 318. E636-E945 (2020))

Aw, W., Jia, H., Lyu, W., Fukuda, S., Tomita, M., Otani, L. and Kato, H. Integrated omics profiling of dextran sodium sulfate-induced colitic mice supplemented with Wolfberry (Lycium barbarum) Sci. Food,. 4, 5 (2020)

2019

Original Papers

Jia, H., Nogawa, S., Kawafune, K., Hachiya, T., Takahashi, S., Igarashi, M., Saito, K. and Kato H. GWAS of habitual coffee consumption reveals a sex difference in the genetic effect of the 12q24 locus in the Japanese population. BMC Genet., 20, 61 (2019)

Igarashi, M., Nogawa, S., Kawafune, K., Hachiya, T., Takahashi, S., Jia, H., Saito, K and Kato, H. Identification of the 12q24 locus associated with fish intake frequency by genome-wide meta-analysis in Japanese populations.Genes Nutr. 14, 21(2019)

Yagi, T., Toyoshima, Y., Tokita, R., Taguchi, Y., Okamoto, Y, Takahashi, SI, Kato, H. and Minami, S. Low-protein diet enhances adiponectin secretion in rats. Biosci. 1774-1781 (2019) Biosci.Biotechnol. Biochem.83, 1774-1781(2019)

2018

Original Papers

Miyoshi,M.,Sato,M.,Saito,K.,Otani,L.,Shirahige,k.,Miura,F.,Ito,T.,jia,H.and Kato,H.Meternal protein restriction alters the renal ptgerl DNA methylation state in SHRSP offspring.Nutrients,10, 1436(2018)

Hamano, M., Haraguchi, Y., Sayano, T., Zyano, C., Arimoto, Y., Kawano, Y., Moriyasu, K., Udono, M., Katakura, Y., Ogawa, T., Kato, H. and Furuya, S. Enhanced vulnerability to oxidative stress and induction of inflammatory gene
exprssion in 3-phosphoglycerate dehydrogenase-deficient fibroblasts. FEBS Open Bio, 914-922(2018)

2017

Original Papers

Horiucti ,M., Takeda, T., Takanashi, H., Ozaki-Masuzawa, Y., Taguchi, Y.,Toypshima, Y., Otani, L., Kato, H., Sone-Yonezawa, M.,Hakuno, F., Takahashi, S.-I. and Takenaka, A. Branched-chain amino acid supplementation restores
reduced insulinotropic activity of a low-protein diet through the vagus nerve in rats. Nutr.Metab. 14, 59 (2017)

Taguchi, Y., Tokita, R., Kato, H., Takahashi, S.-I., and Minami, S. Triglyceride synthesis in hepatocytes isolated from rats fed a low-protein diet is enhanced independently of upregulation of insulin signaling. Biochem. Biophys. Res. Commun. 490,800-805 (2017)

Lyu, W., Jia, H., Deng, C., Saito, K., Yamada, S. and Kato, H. Zeolite-containing mixture supplementation ameliorated dextran sodium sulphate-induced colitis in mice by suppressing the inflammatory bowel disease pathway and improving apoptosis in colon mucosa. Nutrients 9, 467 (2017)

Jia, H., Hanate, M., Aw, W., Itoh, H., Saito, K., Kobayashi, S., Hachimura, S., Fukuda, S., Tomita, M., Hasebe, Y. and Kato. H. Eggshell membrane powder ameliorates intestinal inflammation by faciliating the restitution of epithelial injury and alleviating microbial dybiosis. Sci. Rep. 7, 43993 (2017)

Sato, Y., Uchida, E., Aoki, H., Hanamura, T., Nagamine, K., Kato, H., Koizumi, T. and Ishigami, A. Acerola (Malpighia emarginata DC.) juice intake suppresses the UVB-induced skin pigmentation in SMP30/GNL knockout hairless mice PLoS One, e0170438 (2017)

Takahashi, S., Jia, H., Saito, K. and Kato, H. Comparative integrated omics approach sterically understanding hepatic metabolic dynamics in mouse model. J. Integr. OMICS 7,200 (2017)

Nakamura, K., Morishita, S., Ono, T,. Murakoshi, M., Sugiyama, K., Kato, H., Ikeda, I. and Nishino, H. Lactoferrin interacts with bile acids and increases fecal cholesterol excretion in rats. Biochem. Cell Biol. 95,142-147 (2017)

2016

Original Papers

Aoyama, S., Jia, H., Nakazawa, K., Yamamura, J., Saito, K. and Kato, H. Dietary genistein prevents denervation-induced muscle atrophy in rodents via effects on estrogen receptor-alpha J. Nutr.146, 1146-1154 (2016)

Otani, L,. Mori, T., Koyama, A,. Takahashi, S.-I., and Kato, H. Supplemental arginine above the requirement during suckling causes obesity and insulin resistance in rats. Nutr. Res. 36, 575-585 (2016)

Sayano, T., Kawano, Y., Kusada, W., Arimoto, Y., Esaki, K., Hamano, M., Udono, M., Katakura, Y., Ogawa, T., Kato, H., Hirabayashi, Y. and Furuya, S. Adaptive response to L-serine deficiency is mediated by p38 MAPK activation via deoxysphinganine in normal fibroblasts. FEBS Open Bio 6, 303-316 (2016)

Morishita, S., Kawaguchi H., Ono, T., Miura, N., Murakoshi, M., Sugiyama, K., Kato, H., Tanimoto, A. and Nishino, H. Enteric lactoferrin attenuates the development of high-fat and high-cholesterol diet-induced hypercholesterolemia and atherosclerosis in Microminipigs. Biosci. Biotechnol. Biotechem.80, 295-393(2016)


2015

Original Papers

Morishita, S., Tomita, K., Ono, T., Murakoshi, M., Saito, K., Sugiyama, K., Nishino, H. and Kato, H. Lactoferrin attenuates fatty acid-induced lipotoxicity via Akt signaling in hepatocarcinoma cells. Biochem. Cell Biol. in press (2015)

Ozaki, Y., Saito, K., Nakazawa, K,. Konishi, M., Itoh, N., Hakuno, H., Takahashi, S.-I., Kato, H. and Takenaka, A. Rapid increase of fibroblast growth factor 21 under protein malnutrition and its impact on growth and lipid metabolism. Brit. J. Nutr. in press (2015)

Li, J., Inoue, J., Choi, J.-M., Nakamura, S., Yan, Z., Fushinobu, S., Kamada, H., Kato, H., Hashidume, T., Shimizu, M. and Sato, R. Identification of the flavonoid luteolin as a repressor of the transcription factor hepatocyte nuclear factor 4a . J. Biol. Chem.290, 24021-24031 (2015)

Yoshimura, R, Takai, M., Namaki, H., Minami, K., Imamura, W., Kato, H., Kamei, Y. and Kanamoto R. Down regulation of asparagine synthetase and 3-phosphoglycerate dehydrogenase, and the up-regulation of serine dehydratase in rat liver from intake of excess amount of leucine are not related to leucine-caused amino acid imbalance. J. Nutr. Sci. Vitaminol. 61, 441-448 (2015)

Reviews & Books

Aw, W., Jia, H., Takahashi, S., Fukuda, S. and Kato, H. Chapter 3: The comprehensive understanding of anti-diabetic and anti-obesity effects of coffee intake via nutrigenomics. In: Caffeic acid: Biological properties, structure and health effects. Vaughn, L (ed) Nova Science Publishers, pp. pp. 47-62 (2015)

2014

Original Papers

Takahashi, S., Egashira, K., Jia, H., Saito, K., Abe, K. and Kato, H. Coffee intake down-regulates the hepatic gene expression of peroxisome proliferator-activated receptor gamma in C57BL/6J mice fed a high-fat diet. J. Funct. Foods, 6, 157-167 (2014)

Fukushima, E., Monoi, N., Mikoshiba, S., Hirayama, Y., Serizawa, T., Adachi, K., Koide, M., Ohdera, M., Murakoshi, M. and Kato, H. Protective effects of acetaminophen on ibuprofen-induced gastric mucosal damage in rats with associated suppression of matrix metalloproteinase. J. Pharmacol. Exp. Ther. 349, 165-173 (2014)

Takahashi, S., Saito, K., Jia, H. and Kato, H. An integrated multi-omics study revealed metabolic alterations underlying the effects of coffee consumption. PLoS One, 9, e91134 (2014)

Toyoshima, Y., Tokita, R., Taguchi, Y., Akiyama-Akanishi, N., Takenaka, A., Kato, H., Chida, K., Hakuno, F., Minami, S. and Takahashi, S.-I. Tissue-specific effects of protein malnutrition on insulin signaling pathway and lipid accumulation in growing rats. Endocr. J. 61, 499-512 (2014)

Jia, H., Aw, W., Egashira, K., Takahashi, S., Aoyama, S., Saito, K., Kishimoto, Y. and Kato, H. Coffee intake mitigated inflammation and obesity-induced insulin resistance in skeletal muscle of high-fat diet-induced obese mice. Genes Nutr. 9, 389 (2014)

Nekohashi, M., Ogawa, M., Ogihara, T., Nakazawa, K., Kato, H., Misaka, T., Abe, K. and Kobayashi, S. Luteolin and quercetin affect the cholesterol absorption mediated by epithelial cholesterol transporter Niemann–Pick C1-like 1 in Caco-2 cells and rats. PLoS One, 9, e97901 (2014)

Chang, W.-C., Jia, H., Aw, W. Saito, K., Hasegawa, S. and Kato, H. Beneficial effects of soluble dietary Jerusalem artichoke (Helianthus tuberosus) in the prevention of the onset of Type 2 diabetes and NAFLD in high fructose-fed rats. Brit. J. Nutr. 112, 709-717 (2014)

Jia,H., Aw, W., Hanate, M., Takahashi, S., Saito, K., Tanaka, H., Tomita, M. and Kato, H. Multi-faceted integrated omics analysis revealed Parsley (Petroselinum crispum) as a novel dietary intervention in dextran sodium sulphate induced colitic mice. J. Funct. Foods 11, 438-448 (2014)

Jia, H., Aw, W., Saito, K., Hanate, M,m Hasebe, Y. and Kato, H. Eggshell membrane ameliorates hepatic fibrogenesis in human C3A cells and rats through changes in PPARγ-Endothelin 1 signaling. Sci. Rep., 4, 7473 (2014)

Reviews & Books

Srinivasan,V., Mohamed, M., and Kato, H. Melatonin: its microbicidal propertiesand clinical applications. In: Melatonin and melatonergic drugs in clinical practice. Srinivasan, V., Brzezinski, A., Oter, S. and Shillcutt, S.D. (eds) Springer, pp57-69, (2014)

Jia, H., Tamura, N., Aw, W., Doi, M. and Kato, H. Identification of branched amino acids; Underlying molecular pathways using transcriptomics analysis: Application to cirrhosis. In: Branched chain amino acids in clinical nutrition vol. 2. Rajendram, R., Preedy, V.R. and Patel, V.B. (eds) Humana Press, pp141-157 (2014)

2013

Original Papers

Jia, H., Takahashi,S., Saito, K. and Kato, H. DNA microarray analysis identified molecular pathways mediating the effect of the supplementation of branched amino acids on CCl4-induced cirrhosis in rats. Mol. Nutr. Food Res. 57, 291-306 (2013)

Imamura, W., Yoshimura, R., Takai, M., Yamamura, J., Kanamoto, R. and Kato, H. Adverse effects of excessive leucine intake depend on dietary protein intake: A transcriptomic analysis to identify useful biomarkers. J. Nutr. Sci. Vitaminol. 59, 45-55 (2013)

Ono, T., Fujisaki, C., Ishihara, Y, Ikoma, K., Morishita, S., Murakoshi, M., Sugiyama, K., Kato, H., Miyashita, K., Yoshida, K. and Nishino, H. Potent lipolytic activity of lactoferrin in mature adipocytes. Biosci. Biotechnol. Biochem. 77, 566-571 (2013)

Jia, H., Saito, K., Aw, W., Takahashi, S., Hanate, M, and Kato, H. Transcriptional profiling in rats and an ex vivo analysis implicate novel beneficial function of egg shell membrane in liver fibrosis. J. Funct. Foods 5, 1611-1619 (2013)

2012

Original Papers

Morishita, S., Ono, T., Fujisaki, C., Ishihara, Y., Murakoshi, M., Kato, H., Hosokawa, M., Miyashita, K., Sugiyama, K. and Nishino, H. Bovine lactoferrin reduces visceral fat and liver triglycerides in ICR mice. J. Oleo Sci. (2012)

Jia, H., Takahashi, S., Saito, K. and Kato, H. DNA microarray analysis identified molecular pathways mediating the effect of the supplementation of branched amino acids on CCl4-induced cirrhosis in rats. Mol. Nutr. Food Res. 56, (2012)

Wu, T., ZhuGe, F., Sun, L., Ni, Y., Fu, O., Gao, G., Chen, J., Kato, H. and Fu, Z. Enhanced effect of daytime restricted feeding on the circadian rhythm of streptozotocin-induced type 2 diabetic rats. Am. J. Physiol. Endocrinol. Metab, 302, E1027-1035 (2012)

Ha, B.G., Nagaoka, M., Yonezawa, T., Tanabe, R., Woo, J.T., Kato, H., Chung, U.I. and Yagasaki, K. Regulatory mechanism for the stimulatory action of genistein on glucose uptake in vitro and in vivo. J. Nutr. Biochem 23, 501-509 (2012)

Otani, L., Sugimoto, N., Kaji, M., Murai, M., Chang, S.-J., Kato, H. and Murakami, T. Role of the renin-angiotensin-aldosterone system in the enhancement of salt sensitivity caused by prenatal protein restriction in stroke-prone spontaneously hypertensive rats. J. Nutr. Biochem. 23, 892-899 (2012)

2011

Original Papers

Otani, L., Ogawa, S., Zhao, Z., Nakazawa, K., Umehara, S., Yoshimura, E., Chang, S.-J. and Kato, H. An Optimized Method for the Determination of Free L-Cysteine in Rat Plasma by High-Performance Liquid Chromatography Using the Derivatization Reagent 4-Aminosulfonyl-7-Fluoro-2,1,3-Benzoxadiazole. Biosci. Biotechnol. Biochem. 75, 2119-2124 (2011)

Jia, H., Ren, H., Deng, C., Kato, H. and Endo, H. Evaluation of the antioxidant potential of Chinese parsley (Coriandrum sativum) as compared with a synthetic antioxidant in diet. Int. J. Food Prop.

Jia, H., Ren, H., Deng, C., Kato, H. and Endo, H. Antioxidant potential of Western parsley (Petroselinum crispum) extract and its effects on oxidative stabilities of food during storage. J. Food Biochem

Otani, L., Sugimoto, N., Kaji, M., Murai, M., Chang, S.-J., Kato, H. and Murakami, T. Role of the renin-angiotensin-aldosterone system in the enhancement of salt sensitivity caused by prenatal protein restriction in stroke-prone spontaneously hypertensive rats. J. Nutr. Biochem

Ha, B.G., Nagaoka, M., Yonezawa, T., Tanabe, R., Woo, J.T., Kato, H., Chung, U.I. and Yagasaki, K. Regulatory mechanism for the stimulatory action of genistein on glucose uptake in vitro and in vivo. J. Nutr. Biochem

Wu, T., Sun, L., ZhuGe, F, Guo, X., Zhao, Z., Tang, R., Chen, Q., Chen, L., Kato, H. and Fu, Z. Differential roles of breakfast and supper in rats of a daily three-meal schedule upon circadian regulation and physiology. Chronobiol. Int. 28, 890-903

Takahashi, S., Masuda, J., Shimagami, H., Ohta, Y., Kanda, T., Saito, K. and Kato, H. Mild caloric restriction up-regulates the expression of prohibitin: A proteome study. Biochem. Biophys. Res. Commun. 405, 462-467

Ono, T., Morishita, S., Fujisaki, C., Ohdera, M., Murakoshi, M., Iida, Kato, H., N., Miyashita, K., Iigo, M., Yoshida, T., Sugiyama, K. and Nishino, H. Effects of pepsin and trypsin on the anti-adipogenic action of lactoferrin against pre-adipocytes derived from rat mesenteric fat. Brit. J. Nutr. 105, 200-211

Wu, T., Ni, Y., Zhue, F., Sun, L., Xu, B., Kato, H. and Fu, Z. Significant dissociation of expression patterns of the basic helix-loop-helix transcription factors Dec1 and Dec2 in rat kidney. J. Exp. Biol. 214 (Pt. 8), 1257-1263

Reviews & Books

Kato, H., Takahashi, S. and Saito, K. Omics and integtrated omics for the promotion of food and nutrition science. J. Trad. Comp. Med. 1, 25-30 (2011)

2010

Original Papers

Dong, Y., Wu, T., Ni, Y.H., Kato, H., Fu, Z.W. Effect of fasting on the peripheral circadian gene expression in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 298, 635-641

Wu, T., Ni, Y., Dong, Y., Kato, H. and Fu, Z.W. Regulation of circadian gene expression in the kidney by light and food cues in rats. Biol. Rhythm Res.41, 41-47

Saito, K., Ohta, Y., Sami, M., Kanda, T. and Kato, H. Effect of mild restriction of food intake on gene expression profile in the liver of young rats: reference data for in vivo nutrigenomics study. Brit. J. Nutr. 104, 941-950

Kamei, A., Watanabe, Y., Ishijima, T., Uehara, M., Arai, S., Kato, H., Nakai, Y. and Abe, K. Dietary iron deficiency induces a variety of metabolic changes and even apoptosis in rat liver: a DNA microarray study. Physiol. Genomics . 42,149-156

Wu, T., Ni, Y., Kato, H. and Fu, Z. Feeding-induced rapid resetting of the hepatic circadian clock is associated with acute induction of Per2 and Dec1 transcription in rats. Chronobiol. Int., 27, 1-18

Toyoshima, Y, Tokita, R., Ohne, Y., Hakuno, F., Noguchi, T., Minami, S., Kato, H. and Shin-Ichiro Takahashi, S.I. Dietary Protein Deprivation Up-Regulates Insulin Signaling and inhibits Gluconeogenesis in Rat Liver. J. Mol. Endocrinol. 45, 329-340

Reviews & Books

Abe, K., Kato, H., Yasuoka, A. and Nakai, Y. Genomics applied to nutrients and functional foods in Japan: State of the art. In: Genomics, proteomics, and metabolomics in nutraceuticals and functional foods. Bagchi, D., Lau, F.C. and Bagchi, M (Eds.) Wiley-Blackwell, U.S.A., pp127-145

Kato, H. 1. 9, Transcriptome analyses, Section., 5-1 Functionality of Soy Protein, "All About Soy". (Japanese) Kitamura, K. and others (Eds.) Science Forum, Tokyo. pp185-188

Takahashi, S., Takenaka, A., Toyoshima, Y., Kimura, K., Kato, H. Hukushima,T. Yamanaka, D., Hakuno, H., Minami, S and Iwashita, M. Insulin-like growth factors: Hormones that control development and growth. (Japanese) Journal of Japan Society for Premature and Newborn Medicine, 22, 19-25

Kato, H. Chapter12, Evaluation of the safety of food based on comprehensive gene expression analyses., The development of food society Science ~Toward Risk assessment and Control~, (Japanese) The Univercity of Tokyo, Research Center for Food Safety. (Eds.) CMC Publishing,Tokyo, pp98-102

Srinivasan, V., Pandi-Perumal, S.R., Spence, W., Kato, H. and Cardinali, D.P. Melatonin in septic shock: Some recent concepts. J. Crit. Care, 25, 656.e1-656.e6

Kato, H. and Saito, K. 6-1 Food database, Application to food. "The handbook for pratical use of biochiop" (Japanese) Kaneko, S and Horiike, Y. (Eds.) NTS Inc, Tokyo. pp346-352

Kato,H. Chapter4-5, Metabolism of Nitrogen Compounds., Introduction to Molecular Biology - For the Understanding of Current Nutrition - (Japanese) Koseikan Co.,Ltd. pp106-114

Otani,L., Kato,H. and Murakami,T. Fetal programming of hypertension., Jounal of Clinical and Experimental Medicine 235, (Japanese) Ishiyaku Publishers Inc, Tokyo. pp833-837

2009

Original Papers

Otani, L., Ninomiya, T., Murakami, M., Osajima, K., Kato, H. and Murakami, T. Sardine peptide with angiotensin I converting enzyme inhibitory activity improves glucose tolelance in stroke-prone spontaneously hypertensive rats. Biosci. Biotechnol. Biochem.73, 2203-2209 (2009)

Wu, T., Dong, Y., Yang, Z.Q., Kato, H., Ni, Y.H., and Fu, Z.W. Differential resetting process of circadian gene expression in rat pineal glands after the reversal of the light/dark cycle via a 24-h light or dark period transition. Chronobiol. Int. 26, 793-807 (2009)

Hirao, T., Watanabe, S., Temmei, Y., Hiramoto, M. and Kato, H. Qualitative PCR methods for detecting major food allergens (peanut, soybean, and wheat) by using internal transcribed spacer region. J. AOAC Int.92, 1464-1472 (2009)

Reviews & Books

Kato, H. Chapter7 (Translation) Protein requirements of adults, including elderly, and women during prognancy and loctation. Protein and Amino Acid Requirements in Human Nutrition Report of a Joint WHO/FAO/UNU Expert Consultation Technical Report Series.The Japanese Society for Amino Acid Sciences. Ishiyaku Publishers,Inc.Tokyo, pp79-102 (2009)

2008

Original Papers

Wu, T., Jin, Y.X., Kato, H. and Fu, Z.W. Light and food signals cooperate to entrain the rat pineal circadian system. J. Neurosci. Res. 86, 3246-3255 (2008)

Niwa, Y., Nishiyama, C., Nakano, N., Kamei, A., Kato, H., Kanada, S., Ikeda, S., Ogawa, H. and Okumura, K. Opposite effects of PU.1 on mast cell stimulation. Biochem. Biophys. Res. Commun.375, 95-100 (2008)

Wu, T., Jin, Y.X., Ni, Y.H., Zhang, D.P., Kato, H. and Fu, Z.W. Effects of light cues on re-entrainment of the food-dominated peripheral clocks in mammals. Gene, 419, 27-34 (2008)

Nakai, N., Hashida, H., Kadota, K., Minami, M., Shimizu, K., Matsumoto, I., Kato H. and Abe, K. Genes related to the ubiquitin-proteasome system are up-regulated in the brown adipose tissue of 24 h-fasted rats. Biosci. Biotechnol. Biochem. 72, 139-148 (2008)

Reviews & Books

Hirao, T., Watanabe, S., Hiramoto, M., Taguchi, H., Temmei, Y. and Kato, H. Qualitative and quantitative PCR methods for detecting food allergens by using internal transcribed spacer region. J. Clin. Biochem. Nutr. 43(S1), 227-231 (2008)

Kato, H. Nutrigenomics: the cutting edge and Asian perspectives. Asia Pac. J. Clin. Nutr. 17(S1), 12-15 (2008)

2007

Reviews & Books

Kato, H. Nakai,Y. and Abe,K. (Translation) Genomics,poteomics,metabolomics and systems biology approaches to nutrition. Present Knowledge in Nutrition, 9th Edition. Kimura,S.and Kobayashi,S. (Eds. ), Kenpakusya, Tokyo. pp3-20 (2007)

Kato, H. and Tuji,S. Transcriptome analysis of the effect of soy protein intake in cholesterol-loaded rats.(Japanese) - Soy Protein Research.10, 76-82 (2007)

Kato, H. Part5, Chapter1, DNA microarray analysis of anti-obesty food factors In: Development of anti ‐ obesity functional food materials and application for practical use : establishment and application of biomarkers for metabolic syndrome research (Japanese) , Osawa,T. (Ed.), CMC Publishing,Tokyo, pp59-68, (2007)

Nishiyama,M. Kato, H. Yoshida,N. Yamaguchi, I. Miyakawa,T. Ojika,M. Kobae, and M. Hioka,Y. Implementation of online manuscript submission and review system and its impact : Experience of the Japan Society for Bioscience, (Japanese) Biotechnology and Agrochemistry. 50, 429-436 (2007)

Kato, H. Kobayashi, S, Katsuya, T. and Mitani,Y. New trends in nutrigenomics-Towards practice of tailor-made nutrition. (Japanese) Bioscience & Industry.65.19-23 (2007)

Kato, H. Part IV, Functional food and nutrigenomics -3. Examples, ibid -5, Safety genomics. In:The Encyclopedia of Functional Food. (Japanese) (Arai,S. and others. Eds.) , Asakura Publishing, Tokyo, pp394-399, pp428-430 (2007)

Kato, H. Hayashi,Y. Takahashi,M. Furuya,S. Kishi,K. and Kadowaki,M. Amino Acid Nutrition from the Viewpoint of Evolution. (Japanese) Nippon Eiyo Syokuryo Gakkaishi. 60.151-166 (2007)

Kato, H. Chapter5; Nutrigenomics analysis of the functionality of amino acids.In:Functionality of amino acids : new research waves in life sciences. (Japanese), Japanese Society of Nutrition and Food Science., (Ed.), Kenpakusya, Tokyo. pp171-187 (2007)

Kato, H. Chapter79; Regulation of gene expression by amino acids. In:Nutrition of Proteins and Amino Acids. (Japanese) , Kishi,K. and Kido,Y. (Eds.), Kodansha, Tokyo. pp82-94 (2007)

Noguchi,T. Kato, H. Ooishi,Y. Chapter2; Metabolism of protein and amino acids In:Science of Proteins and Amino Acids. (Japanese) , The Research Committee of Essential Amino Acids. (Ed.), Kogyo Chosakai Publishing,Tokyo. pp65-115, (2007)

2006

Original Papers

Hirao, T., Hiramoto, M., Imai, S. and Kato, H. A novel PCR method for quantification of buckwheat using a unique internal standard material. J. Food. Protect.69, 2478-2486 (2006)

Ohta, Y., Sami, M., Kanda, T., Saito, K., Osada, K. and Kato, H. Gene expression analysis of the anti-obesity effect by apple polyphenols in rats fed a high fat diet or a normal diet. J. Oleo Sci. 55, 305-314 (2006)

Narasaka, S., Endo, Y., Fu, ZW., Moriyama, M., Arai, S., Abe, K. and Kato, H. Safety evaluation of hypoallergenic wheat flour using a DNA microarray. Biosci. Biotechnol. Biochem.70, 1464-1470 (2006)

Reviews & Books

Kato, H. and Tsuji,S. Nutrigenomics study of soy protein function in light of dietary life. (Japanese) Soy Protein Research. 9, 102-107 (2006)

Kato, H. 7.2.Examples of DNA microarray analyses of food functionality. In:Anti-aging and functional foods ; why is it a biomarker now? (Japanese), Yoshikawa,T. and Oosawa,T. (Ed.), CMC Publishing, Tokyo. pp214-220 (2006)

Kato, H. Evaluation of food functionality using DNA chips. (Japanese) JPAPAN FOOD SCIENCE.45, 70-76 (2006)

Kato, H. and Yoshizawa,F. 2.5.2.Protein biosynthesis. In:Handbook of data for nutrition and food science (Japanese) , Japanese Society of Nutrition and Food Science. (Ed.), DOBUNSHOIN, Tokyo. pp87-90 (2006)

2005

Original Papers

Saito, K., Arai, S. and Kato, H. A nutrigenomics database - Integrated repository for publications and associated microarray data in nutrigenomics research. Brit. J. Nutr.94, 493-495 (2005)

Ohne, Y., Toyoshima, Y. and Kato, H. Disruption of the availability of amino acids induces a rapid reduction of serine phosphorylation of insulin receptor substrate-1 in vivo and in vitro. Biosci. Biotechnol. Biochem. 69, 989-998 (2005)

Tachibana, N., Matsumoto, I., Fukui, K., Arai, S., Kato, H., Abe, K. and Takamatsu, K. Intake of soy protein isolate alters hepatic gene expression in rats. J. Agric. Food Chem. 53, 4253-4257 (2005)

Hirao, T., Imai, S., Sawada, H., Shiomi, N., Hachimura, S. and Kato, H. PCR method for detecting trace amounts of buckwheat (Fagopyrum spp.) in food. Biosci. Biotechnol. Biochem.69, 724-731 (2005)

Reviews & Books

Kato, H., Saito, K. and Kimura, T. A perspective on DNA microarray technology in food and nutritional science. Curr. Opin. Clin. Nutr. Metab. Care, 8, 516-522 (2005)

Matsuzaki, K., Kato, H., Sakai, R., Toue, S., Amao, M. and Kimura, T. Transcriptomics and metabolomics of dietary leucine excess. J. Nutr. 135, 1571S-1575S (2005)

Oda,H. Kato, and H. Seki,T. (Ed.), In: Health Nutrition - Nutritional Physiological Chemistry as Health Science. KYORITSU SHUPPAN, Tokyo. (2005)

Kato, H.5.4. Reception and transduction of dietary signals in the endocrine system. In:Food Science. Kaminogawa,S. and Tanokura,M. (Ed.), Tokyo Kagaku Dojin, Tokyo. pp134-138 (2005)

Kato, H. A new tide in nutritional science: From molecular nutrition to nutrigenomics. Shokuhin to Gijutsu. 404, 1-9 (2005)

Kato, H. Transcriptomics for the estimation of the functionality and safety of proteins. Journal of Japanese Council for Advanced Food Ingredients Research. 7, 1-7 (2005)

Kato, H. Functional analysis of food proteins and transcriptomics. Journal of Japanese Society of Clinical Nutrition 26, 207-211 (2005)

2004

Original Papers

Toyoshima, Y., Ohne, Y., Takahashi, S.-I., Noguchi, T. and Kato, H. Dietary protein deprivation decreases the serine phosphorylation of insulin receptor substrate-1 in rat skeletal muscle. J. Mol. Endocrinol.32, 519-531 (2004)

Reviews & Books

Oota,Y., Osada,K., Funayama,M., Sami.M., Kanda,T. and Kato, H. Effect of the administration of polyphenols on rats fed a high fat diet using GeneChip. (Japanese),Proceedings of Japanese Conference on the Biochemistry of Lipids .46, 160-163 (2004)

Kato, H., Narasaka, S., Endo, Y., Abe, K. and Arai, S. DNA microarray analyses of the effects of dietary proteins. (Japanese) Biofactors 21, 11-13 (2004)

Kato, H. Chapter8. Protein. (Collaborator; Noguchi,T.) Chapter14. Digestion and absorption. In:Basic Nutrition. (Japanese), Kurata,T. and others. (Ed.) Tokyo Kagaku Dojin, Tokyo. pp80-107, pp184-197 (2004)

Kato, H. Chapter15; Nutrition & genetic science (Translator) Human nutrition and dietetics. Hosoya,N. (Ed.) Ishiyaku Publishers, Tokyo. pp299-309 (2004)

2003

Original Papers

Imae, M., Fu, ZW., Yoshida, A., Noguchi, T. and Kato, H. Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16. J. Mol. Endocrinol.30, 253-262 (2003)

Oishi, Y., Kato, H. and Noguchi, T. Dietary protein is a potent regulator of the hyaluronan synthase gene in rat skin. Biosci. Biotechnol. Biochem.67, 736-742 (2003)

Reviews & Books

Kato, H. Chapter15. Nitrogen metabolism II: Degradation. (Translator) Biochemistry; the molecular basis of life; The 3rd Edition ( Ichikawa,A. Ed.) Kagakudojin, pp459-484 (2003)

Kato, H. 3.3.3 a. Molecular Nutrition., 3.3.3.b.2) Hormone and nutrition. In: The Encyclopedia of Agrochemistry. (Japanese) , Suzuki,A. and Arai,S. (Eds.), Asakura Publishing, Tokyo. C. pp424-426, pp429-431 (2003)

Kato, H. and Kimura, T. Evaluation of the effects of the dietary intake of proteins and amino acids by DNA microarray technology. J. Nutr. 133, 2073S-2077S (2003)

2002

Original Papers

Fu,ZW., Yoneyama, M., Noguchi, T. and Kato , H. Response of the IGF system to vitamin A depletion and repletion in rats. J. Nutr. Sci. Vitaminol.48, 453-460 (2002)

Endo, Y., Fu, Z.W., Abe, K., Arai, S. and Kato, H. Dietary protein quantity and quality affect rat hepatic gene expression. J. Nutr.132, 3632-3637 (2002)

Oishi, Y., Fu, Z.W., Ohnuki, Y., Kato, H. and Noguchi, T. Molecular basis of the alteration in skin-collagen metabolism in response to in vivo dexamethasone treatment: Effects on syntheses of collagen type I and III, collagenase, and TIMPs. Brit. J. Dermatol.147, 859-868 (2002)

Tachibana, T., Tanaka, S., Furuse, M., Hasegawa, S., Kato, H. and Sugahara, K. Intracerebroventricular injection of glucagon-like peptide-1 decreases monoamine concentrations in the hypothalamus of chicks. Brit. Poultry Sci.43, 122-126 (2002)

Oishi, Y., Fu, Z.W., Ohnuki, Y., Kato, H. and Noguchi, T. Effects of protein deprivation on a1(I) and a1(III) collagen and its degrading system in rat skin. Biosci. Biotechnol. Biochem.66, 117-126 (2002)

Fu, Z.W., Inaba, M., Noguchi, T. and Kato, H. Molecular cloning and circadian regulation of cryptochrome genes in the Japanese quail (Coturnix coturnix japonica). J. Biol. Rhythms17, 14-27 (2002)

Reviews & Books

Kato, H. Molecular nutrition of protein metabolism. In:Molecular Nutrition: Molecular Biology of Nutrients and Life Style-Related Diseases. Kakinuma,A. (Ed.) Koseikan, Tokyo. pp50-64 (2002)

2001

Original Papers

Fu, Z.W., Kato, H, Kotera, N., Noguchi, T., Sugahara, K. and Kubo, T. Regulation of hydroxyindole-O-methyltransferase gene expression in Japanese quail (Coturnix coturnix japonica). Biosci. Biotechnol. Biochem.65, 2504-2511 (2001)

Matsukawa, T., Inoue, Y., Oishi, Y., Kato, H. and Noguchi, T. Up-regulation of upstream stimulatory factors by protein malnutrition and its possible role in regulation of the IGF-binding protein-1 gene. Endocrinology, 142, 4643-4651 (2001)

Fu, ZW., Noguchi, T. and Kato, H. Differential regulation of IGFBP-2 and IGFBP-5 gene expression by vitamin A status in Japanese quail. Am. J. Physiol.281, E138-E146 (2001)

Fu, ZW., Kubo, T., Sugahara, K., Noguchi, T. and Kato, H. Retinoid nutritional status differently affects the expression of quail RARb isoform transcripts in a tissue-specific manner. J. Endocrinol.169, 281-290 (2001)

Fu, ZW., Noguchi, T. and Kato, H. Vitamin A deficiency reduces IGF-I gene expression and increases IGF-I receptor and insulin receptor gene expression in tissues of Japanese quail (Coturnix coturnix japonica). J. Nutr.131, 1189-1194 (2001)

Fu, ZW, Kubo, T., Noguchi, T. and Kato, H. Developmental changes in the mRNA levels of IGF-I and its related genes in the reproductive organs of Japanese quail (Coturnix coturnix japonica) Growth Horm. IGF Res.11, 24-33 (2001)

Fu, ZW, Kubo, T., Sugahara, K, Noguchi, T. and Kato, H. Cloning of cDNAs encoding quail (Coturnix coturnix japonica) retinoic acid receptor b isoforms and changes in their gene expression during gonadotropic growth. Biol. Reprod.64, 231-241 (2001)

Reviews & Books

Kato, H. Methods of molecular biology. In:Experimental Techniques for Animal Nutrition. Ishibashi.T, (Super Visor), pp380-394 (2001)

2000

Original Papers

Tachibana, T., Uchimura, D., Kato, H., Kubo, T. and Sugahara, K. Extracellular norepinephrine in the medial hypothalamus increases during feeding in chicks: A microdialysis study. Comp. Biochem. Physiol.127A, 331-338 (2000)

Imae, M., Inoue, Y., Fu, ZW., Kato, H. and Noguchi, T. Gene expression of the three members of hepatocyte nuclear factor-3 is differentially regulated by nutritional and hormonal factors. J. Endocrinol.167, R1-R5 (2000)

Fu, ZW., Kato, H. Sugahara, K and Kubo, T. Retinoic acid accelerates the development of reproductive organs and egg production in Japanese quail (Coturnix coturnix japonica). Biol. Reprod.63, 1795-1800 (2000)

Kato, H., Okubo, Y., Matsumura, Y., Roberts, C.T., Jr., Sugahara, K. and LeRoith, D. The tyrosine kinase activity of the chicken insulin receptor is similar to that of the human insulin receptor. Biosci. Biotechnol. Biochem.64, 903-906 (2000)

Reviews & Books

Kato, H. Primary cultured hepatocytes. In:Experimental Methods for the Studies of Protein Metabolism. (Japanese) , Noguchi,T., Hunabiki,R. and Kadowaki, M. (Eds.) Japan Scientific Societies Press pp115-128 (2000)

Kato, H. Endocrine regulation. In:Experimental Methods for Food Functionality. (Japanese) , Shinohara,K., Suzuki,T. and Kaminogawa,K. (Eds.) KORIN PUBLISHING, Tokyo. pp103-105 (2000)

1999

Original Papers

Sugahara, K., Shimoyama, Y., Kato, H. and Kubo, T. Feeding a lysine-free diet decreases food intake without changes in hypothalamic monoamine concentrations in growing chickens. Anim. Sci. Technol. (Jpn.) 70, 484-489 (1999)

Fu, ZW., Kato, H., Kotera, N., Sugahara, K. and Kubo, T. Regulation of the expression of serotonine N-acetyltransferase gene in Japanese quail (Coturnix japonica): (II) Effect of vitamin A deficiency. J. Pineal Res.27, 34-41 (1999)

Kato, H., Fu, ZW., Kotera, N., Sugahara, K. and Kubo, T. Regulation of the expression of serotonine N-acetyltransferase gene in Japanese quail (Coturnix japonica): (I) Rhythmic pattern and effect of light. J. Pineal Res.27, 24-33 (1999)

1998

Original Papers

Tsuchiya, T., Nagao, Y., Ozawa, A., Matsumoto, M., Sugahara, K., Kubo, T. and Kato, H. Decrease of the obese gene expression in bovine subcutaneous adipose tissue by fasting. Biosci. Biotechnol. Biochem.62, 2068-2069 (1998)

Fu, ZW., Kato, H., Sugahara, K. and Kubo, T. Circadian rhythm of pineal melatonin contents in silky chicks. Jpn. Poult. Sci. 35, 55-59 (1998)

Fu, ZW., Kato, H., Sugahara, K. and Kubo, T. Vitamin A deficiency reduces the responsiveness of pineal gland to light in Japanese quail (Coturnix japonica). Comp. Biochem. Physiol. 119A, 593-598 (1998)

1997

Original Papers

Fu, ZW., Kondo,Y., Iwasaki,N., Kato, H., Sugahara,K., and Kubo,T. Extraction of Melatonin from Chick Pineal and Its Quantification by High-Performance Liquid Chromatography, ( Japanese) The Japanese journal of zootechnical science. 68, 1154-1160 (1997)

Shim, S., Fu, ZW., Kato, H. and Tanaka, H. Diurnal changes in the enzyme activity and the messenger RNA level of pineal serotonin N-acetyltransferase in normal and hereditary microphthalmic rats. Biosci. Biotechnol. Biochem. 61, 2113-2115. (1997)

Fu, ZW., Kubo, T. and Kato, H. Analyses of serotonin N-acetyltransferase mRNA content in rat pineal grand and testis by an improved assay system - Micro lysate assay. Anim. Sci. Technol. (Jpn.) 68, 893-896 (1997)

Fu, ZW., Ohara, S., Kato, H., Sugahara, K. and Kubo, T. Retinoic acid accelerates the testicular maturation in Japanese quail. Anim. Sci. Technol (Jpn) , 68, 420-422 (1997)

Najjar, S.M., Blakesley, V.A., Li Calzy, S., Kato, H., LeRoith, D. and Choice, C.V. Differential phosphorylation of pp120 by insulin and insulin-like growth factor-1 receptors: Role for the C-terminal domain of the b-subunit. Biochemistry, 36, 6827-6834 (1997)

Reviews & Books

Kato, H. and Fu, ZW. Studies in Molecular Nutrition. Genes Which Yield Multiple mRNA Species. (Japanese) Nippon Eiyo Shokuryo Gakkaishi,50, 377-379 (1997)

Kato, H. Studies on Molecular on Molecular Biology of IGF-I Action. (Japanese) Journal of the Agricultural Chemical Society of Japan. 71, 1141-1146 (1997)

1996

Original Papers

Matsumura, Y., Domeki, M., Sugahara, K., Kubo, T., Roberts, C.T., Jr., LeRoith, D. and Kato, H. Nutritional regulation of insulin-like growth factor-I receptor mRNA levels in growing chickens. Biosci. Biotechnol. Biochem.60, 979-982 (1996)

Reviews & Books

Kato, H., Noguchi, T. and LeRoith, D. Nutritional regulation of gene expression of IGFs and their related proteins. In: Gene expression and nutrition: From cells to whole body. Muramatsu, T. (Ed.) Research Signpost, India, pp25-43 (1996)

1995

Original Papers

Stannard, B., Blakesley, V.A., Kato, H., Roberts, C.T., Jr. and LeRoith, D. Single tyrosine substitution in the insulin-like growth factor I receptor inhibits ligand-induced receptor autophosphorylation and internalization, but not mitogenesis. Endocrinology, 136, 4918-4924 (1995)

Surmacz, E., Sell, C., Swantek, J., Kato, H., Roberts, C.T., Jr., LeRoith, D. and Baserga, R. Dissociation of mitogenesis and transforming activity by C-terminal truncation of the insulin-like growth factor-I receptor. Exp. Cell. Res. 218, 370-380 (1995)

Blakesley, V.A., Kato, H., Roberts, C.T., Jr. and LeRoith, D. Mutation of a conserved amino acid residue (tryptophan 1173) in the tyrosine kinase domain of the IGF-I receptor abolishes autophosphorylation but does not eliminate biologic function. J. Biol. Chem. 270, 2764-2769 (1995)

1994

Original Papers

Mastick, C.C., Kato, H., Roberts, C.T., Jr., LeRoith, D. and Saltiel, A.R. Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation. Endocrinology, 135, 214-222 (1994)

Faria, T.N., Blakesley, V.A., Kato, H., Stannard, B., LeRoith, D. and Roberts, C.T.,Jr. Role of the carboxyl-terminal domains of the insulin and insulin-like growth factor I receptor function. J. Biol. Chem. 269, 13922-13928 (1994)

Kato, H., Faria, T.N., Stannard, B., Roberts, C.T.,Jr. and LeRoith, D. Essential role of tyrosine residues 1131, 1135 and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action. Mol. Endocrinol. 8, 40-50 (1994)

Reviews & Books

Kato,H., Faria, T.N., Blakesley, V., Roberts, C.T., Jr. and LeRoith, D. Pathological alterations in various components of the insulin-like growth factor signalling system. In: Molecular basis of endocrine diseases (Series: Frontiers in endocrinology 7) Isidori, A., New, M.I., Sesma, C.P.(Eds) Ares-Serono Symposia Publications, Rome, pp105-118 (1994)

1993

Original Papers

Takenaka, A., Hirosawa, M., Mori, M., Yamada, S., Miura, Y., Kato, H., Takahashi, S.I. and Noguchi, T. Effect of protein nutrition on the messenger RNA content of insulin-like growth factor binding protein-1 in liver and kidney of rats. Brit. J. Nutr. 69, 73-82 (1993)

Kato, H., Faria, T.N., Stannard, B., Levy-Toledano, R., Taylor, S.-I., Roberts, C.T., Jr. and LeRoith, D. Paradoxical biological effects of overexpressed insulin-like growth factor-I receptors in Chinese hamster ovary cells. J. Cell. Physiol. 156, 145-152 (1993)

Kato, H., Faria, T.N., Stannard, B., Roberts, C.T., Jr. and LeRoith, D. Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of IGF-I mimetic antibody (aIR-3). J. Biol. Chem. 268, 2655-2661 (1993)

Reviews & Books

LeRoith, D., Werner, H., Faria, T.N., Kato, H., Adamo, M. and Roberts, C.T., Jr. Insulin-like growth factor receptors - Implications for nervous system function. In: Role of insulin-like growth factors in the nervous systems. Raizada, M.K. and LeRoith, D. (Eds.) New York Academy of Science, New York, pp23-32 (1993)

LeRoith, D., Adamo, M., Kato, H. and Roberts, C.T., Jr. Divergence of insulin and insulin-like growth factor-I signalling pathways. In: Lessons from Laron syndrome. Laron, Z. and Parks, J.S. (Eds.) Karger, Basel, pp346-358 (1993)

1992

Original Papers

Miura, Y., Higashi, Y., Kato, H., Takahashi, S.-I. and Noguchi, T. Effects of dexamethasone on the production of insulin-like growth factor-I and insulin-like growth factor binding proteins in primary cultures of rat hepatocytes. Biosci. Biotechnol. Biochem. 56, 1396-1400 (1992)

Miura, Y., Kato, H. and Noguchi, T. Effect of dietary proteins on insulin-like growth factor-I (IGF-I) messenger ribonucleic acid content in rat liver. Brit. J. Nutr. 67, 257-265 (1992)

Reviews & Books

LeRoith, D., McGuiness, M., Shemer, J., Stannard, B., Lanau, F., Faria, T.N., Kato, H., Werner, H., Adamo, M. and Roberts, C.T.,Jr. Insulin-like growth factors. Biosignals, 1, 173-181 (1992)

1991

Original Papers

Takenaka, A., Miura, Y., Mori, M., Hirosawa, M., Kato, H. and Noguchi, T. Distribution of messenger RNAs of insulin-like growth factor (IGF)-binding proteins-1 and -3 between parenchymal and nonparencymal cells in rat liver. Agric. Biol. Chem. 55, 1191-1193 (1991)

Umezawa, T., Kajikawa, M., Ohsawa, Y., Miura, Y., Kato,H. and Noguchi, T. Effect of protein deprivation on insulin-like growth factor-binding proteins in rats. Brit. J. Nutr. 66, 105-116 (1991)

Reviews & Books

Kato, H., Umezawa, T., Miura, Y. and Noguchi, T. The effect of quantity and nutritional quality of dietary proteins on plasma concentration of insulin-like growth factor binding proteins (IGFBP) and the saturability of IGFBP with endogenous IGF-I. Adv Exp Med Biol. 293, 171-178 (1991)

1990

Original Papers

Takahashi, S., Kajikawa, M., Umezawa, T., Takahashi, S.-I., Kato, H., Miura, Y., Nam, T.J., Noguchi, T. and Naito, H. Effect of dietary proteins on the plasma immunoreactive insulin and insulin-like growth factor-I/somatomedin C concentration in the rat. Brit. J. Nutr.63, 521-534 (1990)

Nam, T.J., Noguchi, T., Funabiki, R., Kato, H., Miura, Y. and Naito, H. Correlation between the urinary excretion of acid soluble peptides, fractional synthesis rate of whole body proteins, and plasma insulin-like growth factor-I/somatomedin C concentration in the rat. Brit. J. Nutr.63, 515-520 (1990)

Kato, H., Takenaka, A., Miura, Y., Nishiyama, M. and Noguchi, T. Evidence of introduction by molecular cloning of artificial inverted sequence at the 5' terminus of the sense strand of rat insulin-like growth factor-I cDNA. Agric. Biol. Chem. 54, 2225-2230 (1990)

Kato, H., Okoshi, A., Miura, Y. and Noguchi, T. A new cDNA clone relating to larger molecular species of rat insulin-like growth factor-I mRNA. Agric. Biol. Chem. 54, 1599-1601 (1990)

1989

Original Papers

Takahashi, S.-I., Ohishi, Y., Kato, H., Noguchi, T., Naito, H. and Aoyagi, T. The effects of bestatin, a microbial aminopeptidase inhibitor, on epidermal growth factor- induced DNA synthesis and cell division in primary cultured hepatocytes of rats. Exp. Cell Res. 183, 399-412 (1989)

Takenaka, A., Tayama, T., Takahashi, S.-I., Kato, H., Noguchi, T. and Naito, H. Microinjection of endogenous proteins into primary cultures of rat hepatocytes and the degradation of the injected proteins. Int. J. Biochem. Cell Biol. 21, 497-508 (1989)

Kato, H., Takahashi, S.-I., Takenaka, A., Funabiki, R., Noguchi, T. and Naito, H. Degradation of endogenous proteins and internalized asialofetuin in primary cultured hepatocytes of rats. Int. J. Biochem.Cell Biol. 21, 483-495 (1989)

Reviews & Books

Kato, H., Miura, Y., Okoshi, A., Umezawa, T., Takahashi, S.-I. and Noguchi, T. Dietary and hormonal factors affecting the mRNA level of IGF-I in rat liver in vivo and in primary cultures of rat hepatocytes. In: Molecular and cellular biology of insulin-like growth factors and their receptors. LeRoith, D. and Raizada, M. (Eds.) Plenum, New York, pp125-128 (1989)

Noguchi, T., Tayama, T., Takenaka, A., Takahashi, S.-I., Kato,H. and Naito, H. Microinjection of endogenous and exogenous proteins into primary cultured hepatocytes and degradation of the injected proteins. In: Intracellular proteolysis: Mechanism and regulations. Katunuma, N. and Kominami, E (Eds.) Japan Scientific Societies Press, Tokyo, pp485-487 (1989)

Kato, H., Takahashi, S.-I., Funabiki, R., Noguchi, T. and Naito, H. Mechanism and rate of degradation of short- and long-lived proteins in primary cultured rat hepatocytes. In: Intracellular proteolysis: Mechanism and regulations. Katunuma, N. and Kominami, E (Eds.)

1988

Original Papers

Takahashi, S.-I., Kato, H., Seki, T.-I., Takahashi, A., Noguchi, T. and Naito, H. Intermediate peptides of insulin degradation in liver and cultured hepatocytes of rats. Int. J. Biochem. Cell Biol.20, 1369-1380 (1988)

Noguchi, T., Nam, T.J., Kato, H. and Naito, H. Further studies on the nutritional factors affecting the urinary excretion of acid-soluble peptides in rats. Brit. J. Nutr. 60, 321-337 (1988)

1987

Original Papers

Takahashi, S.-I., Kato, H., Takahashi, A., Noguchi, T. and Naito, H. Mode of action of bestatin and leupeptin to induce the accumulation of acid soluble peptides in rat liver in vivo and the properties of the accumulated peptides. The important role of bestatin- and leupeptin- sensitive proteases in the protein degradation pathway in vivo. Int. J. Biochem. Cell Biol.19, 401-412 (1987)

Reviews & Books

Kato, H. Insulin-like growth factor and protein metabolism. Journal of the Agricultural Chemical Society of Japan (Japanese) 16, 1305-1308 (1987)

1985

Original Papers

Takahashi, S.-I., Kato, H., Seki, T.-I., Noguchi, T., Naito, H., Aoyagi, T. and Umezawa, H. Bestatin, a microbial aminopeptidase inhibitor inhibits DNA synthesis induced by insulin or epidermal growth factor in primary cultured rat hepatocytes. J. Antibiot.38, 1767-1773 (1985)

Congresses

2010

Japan-New Zealand Joint Workshop on “Functional Food”(12th, Oct)

12th Japanese-Swiss Meeting on Biotechnology and Bioprocess Development(10th-12th, Oct)

The Meeting of the Kansai Branch of Japan Society for Bioscience, Biotechnology and Agrochemistry, Kansai(2nd, Oct)

The 4th Annual Meeting of the Japanese Society for Amino Acid Sciences (16th-17th, Sep)

The 5th Assembly, Research Association for the Functional Nucleic Acid and Nucleoprotein (6th, Aug)

The 64th Annual Meeting of Japanese Society of Nutrition and Food Science(21st-23rd, May)

The annual Meeting of Japan Society for Bioscience, Biotechnology and Agrochemistry 2010(27th-30th, Mar)

2009

The annual meeting of Japan Ayuruveda(12th, Dec)

The 32nd Annual Meeting of the Molecular Biology Society of Japan (9th-12th, Dec)

The 3rd Food Pharmacy Symposium (12th, Nov)

19th International Congress of Nutrition (4th-9th, Oct)

The 3rd Annual Meeting of the Japanese Society for Amino Acid Sciences (29th-30th, Sep)

The 84th Meeting of the Kanto Branch of Japanese Society of Nutrition and Food Science, Kanto (19th, Sep)

The 4th Assembly, Research Association for the Functional Nucleic Acid and Nucleoprotein (31th, Jul)
Nutrigenomics Database