[学歴]
1965年 東京大学農学部農芸化学科卒業
1967年 東京大学大学院農学系研究科農芸化学専門課程・修士課程修了
1970年 東京大学大学院農学系研究科農芸化学専門課程・博士課程修了
[職歴]
1969年 理化学研究所研究員補
1970年 理化学研究所研究員
1979年 東京大学農学部助教授
1994年 東京大学大学院農学生命科学研究科教授
2004年 東京大学名誉教授、北里研究所・基礎研究所部長、帝京平成大学薬学部教授
（1974-1976年 米国ピッツバーグ大学化学科博士研究員）
[学位] 農学博士
[学位論文] 生理活性天然物の光学活性体に関する研究
[研究内容] 生物活性天然有機化合物の合成
・植物ホルモン、植物生長調節物質、植物保護物質などの合成
・細胞周期阻害物質や酵素阻害剤など、興味深い生命現象解明の
鍵となる物質の合成
・微生物などを用いた物質変換と合成への応用
[発表論文](2000年以降退官時まで）
・ Concise Synthesis of (+,-)-Brevioxime.
Yutaka Nishimura and Takeshi Kitahara, Heterocycles, 2000, 52, 553-556.
・ Synthesis of (+,-)-(3R*,4S*,4aR*)-4,8-Dihydroxy-3-methyl-3,4,4a,5-
tetrahydro-1H-2-benzopyran-1-one.
Kanako Uchida, Hidenori Watanabe and Takeshi Kitahara, Heterocycles,
2000, 53, 539-542.
・Total Synthesis of a Nonclassical Bioactive Acetogenin, (+)-Muconin.
Wen.-Qian Yang and Takeshi Kitahara, Tetrahedron, 2000, 56, 1451-1461.
・ Synthetic Study on Oximidines: A Concise Synthesis of (Z)-Enamides.
Kouji Kuramochi, Hidenori Watanabe and Takeshi Kitahara, Synlett, 2000,
397-399.
・Synthesis of Pironetin and Related Analogs: Studies on Structure-Activity
Relationships as Tublin Assembly Inhibitors.
Hiroyuki Watanabe, Hidenori Watanabe, Takeo Usui, Masuo Kondoh, Hiroyuki Osada
and Takeshi Kitahara, J. Antibiot., 2000, 53, 540-545.
・Regioselective Synthesis of β- and γ-Thujaplicins.
Min-Gyu Soung, Masanao Matsui and Takeshi Kitahara, Tetrahedron, 2000, 56,
7741-7745.
・ First Total Synthesis of Mueggelone.
Ken Ishigami, Hajime Motoyoshi and Takeshi Kitahara, Tetrahedron Lett., 2000, 41,
8897-8901.
・ Synthesis of (4S,6S)-4-Hydroxy-1,7-dioxaspiro[5,5]undecane, a Component of the
Olive Fruit Fly Pheromone, by Employing a Novel Asymmetric Oxy-Michael Addition.
Hidenori Watanabe, Daisuke Itoh and Takeshi Kitahara, Synthesis, 2000, 1925-1929.
・ Radicicol Binds and Inhibits Mammalian ATP Citrase Lyase.
Se Won Ki, Ken Ishigami, Takeshi Kitahara, Koji Kasahara, Minoru Yoshida and Sueharu
Horinouchi, J. Biol. Chem. 2000, 275, 39231-39236.
・Synthesis of Apicidin.
Wataru Kuriyama and Takeshi Kitahara, Heterocycles, 2001, 55, 1-4.
・Synthesis and Revision of the Relative Configuration of Fudecalone.
Hidenori Watanabe, Takahiro Yamaguchi, Takeshi Furuuchi and Takeshi Kitahara,
Tetrahedron Lett., 2001, 42, 917-919.
・ Expeditious Synthesis of Nicotianamine and 2'-Deoxymugineic Acid.
Katsuhiro Miyakoshi, Jun Oshita and Takeshi Kitahara, Tetrahedron, 2001, 57,
3355-3360.
・ A Concise Synthesis of (+)-Preussin.
Masayuki Okue, Hidenori Watanabe and Takeshi Kitahara, Tetrahedron, 2001, 57,
4107-4110.
・Analysis of the Enantiomeric Ratios of Chiral Components in Absolute Jasmine.
Shigeyuki Tamogami, Ken-ichi Awano and Takeshi Kitahara, Flavour Fragr. J. 2001,
16, 161-163.
・Novel Asymmetric Oxy-Michael Addition Reacrion of the Chiral Ketones to the Achiral
γ- or δ-Hydroxy-a,b-Unsaturated Carbonyl Compounds.
Hidenori Watanabe, Kaori Machida, Daisuke Itoh, Haruki Nagatsuka and Takeshi Kitahara,
Chirality, 2001, 13, 379-385.
・ First Total Synthesis and Determination of the Absolute Configuration of Mueggelone.
Hajime Motoyoshi, Ken Ishigami and Takeshi Kitahara, Tetrahedron, 2001, 57, 3899-
3908.
・ Simple Synthesis of (+,-)-Epibatidine.
Balaram Roy, Hidenori Watanabe and Takeshi Kitahara, Heterocycles, 2001, 55, 861-
871.
・ Total Synthesis of (+,-)-Cocculolidine.
Tsuneomi Kawasaki, Naoko Onoda, Hidenori Watanabe and Takeshi Kitahara,
Tetrahedron Lett., 2001, 42, 8003-8006.
・ Development of an Efficient GLC System with a Mixed Chiral Stationary Phase and Its
Application to the Separation of Optical Isomers.
Shigeyuki Tamogami, Ken-ichi Awano Masayasu Amaike and Takeshi Kitahara,
Flavour Fragr. J., 2001, 16, 349-352.
・Synthesis and Biological Evaluation of Analogs of the Tetrahydropyran Acetogenin,
Muconin.
Wen.-Qian Yang, Ken Ishigami and Takeshi Kitahara, Proc. Japan Acad., Ser. B, 2001,
77, 157-160.
・A Synthesis of FR901464.
Masato Horigome, Hajime Motoyoshi, Hidenori Watanabe and Takeshi Kitahara,
Tetrahedron Lett., 2001, 42, 8207-8210.
・Radicicol Binding to Swo1/Hsp90 and Inhibition of Growth of Specific Temperature-
sensitive Cell Cycle Mutants of Fission Yeast.
Se Won Ki, Koji Kasahara, Ho Jeong Kwon, Ken Ishigami , Takeshi Kitahara, Teruhiko
Beppu, Minoru Yoshida and Sueharu Horinouchi, Biosci. Biotechnol. Biochem, 2001,
65, 2528-2534.
・Synthesis of Brevicompanines, Plant Growth Regulators.
Koji Matsumura and Takeshi Kitahara, Heterocycles, 2001, 54, 727-733.
・Synthesis of the Proposed Structure and Revision of Stereochemistry of Kaitocephalin.
Masayuki Okue, Hiroyuki Kobayashi, Kazuo Shin-ya, Kazuo Furihata, Yoichi Hayakawa,
Haruo Seto, Hidenori Watanabe and Takeshi Kitahara, Tetrahedron Lett., 2002, 43,
857-860.
・ The First Synthesis of Kaitocephalin Based on the Structure Revision.
Hidenori Watanabe, Masayuki Okue, Hiroyuki Kobayashi and Takeshi Kitahara,
Tetrahedron Lett., 2002, 43, 861-864.
・A Facile Synthetic Method for Indolic Enamides.
Kouji Kuramochi, Yuko Osada and Takeshi Kitahara, Chem. Lett., 2002, 128-129.
・Short-step Syntheses of All Stereoisomers of Preussin and Their Bioactivities.
Masayuki Okue, Hidenori Watanabe, Koji Kasahara, Minoru Yoshida, Sueharu Horinouchi
and Takeshi Kitahara, Biosci. Biotechnol. Biochem., 2002, 66, 1093-1096.
・ Synthesis of (R)- and (S)-Muscone.
Satoko Fujimoto, Keisuke Yoshikawa, Masamichi Itoh and Takeshi Kitahara,
Biosci. Biotechnol. Biochem., 2002, 66, 1389-1392.
・Formation of Fragrance Materials from Odourless Glycosidically-bound Volatiles by
Skin Microflora (Part 1).
Takeshi Ikemoto, Bun-Ichi Okabe, Kunio Mimura and Takeshi Kitahara, Flavour Fragr. J.,
2002, 17, 452-455.
・Synthesis of the Glycosidic Precursor of Isomeric Marmelo Lactones, Volatile
Components of the Quince Fruit, Cydonia oblonga.
Hiroki Shimizu and Takeshi Kitahara, Biosci. Biotechnol. Biochem., 2002, 66, 743-748.
・ Total Synthesis of (-)-Halicholactone.
Taichi Takahashi, Hidenori Watanabe and Takeshi Kitahara, Heterocycles, 2002, 58,
99-104.
・ Enantioselective Synthesis of (-)-N-Boc-7-azabicyclo[2.2.1]heptan-2-one and
(+)-N-Boc-4-amino-2-cyclohexen-1-one: Formal Total Synthesis of Both Enantiomers
of Epibatidine.
Toru Tachihara, Hiroyuki Watanabe and Takeshi Kitahara, Heterocycles, 2002, 57,
781-785.
・ Absolute Configuration of Migrastatin, a Novel 14-Membered Ring Macrolide.
Hikaru Nakamura, Yoshikazu Takahashi, Hiroshi Naganawa, Koichi Nakae, Masaya Imoto,
Motoo Shiro, Koji Matsumura, Hidenori Watanabe and Takeshi Kitahara, J. Antibiot.,
2002, 55, 442-444.
・ Formation of Fragrant Materials from Odourless Glycosidically-bound Volatiles on Skin
Microflora (Part 2).
Takeshi Ikemoto, Kunio Mimura and Takeshi Kitahara, Flavour Fragr. J., 2003, 18,
45-47.
・ Synthesis and Odor Evaluation of Stereoisomers of Imine Derivatives in Roasted
Spotted Shrimp.
Toru Tachihara, Susumu Ishizaki, Yoshiko Kurobayashi, Hiroshi Tamura, Youichi Ikemoto,
Atsushi Onuma and Takeshi Kitahara, Helv. Chimica. Acta, 2003, 86, 274-279.
・ Total Synthesis of (+)-Epiepoformin, (+)-Epiepoxydon and (+)-Bromoxone Employing a Useful
Chiral Building Block, Ethyl (1R,2S)-5,5-Ethylenedioxy-2-hydroxycyclohexanecarboxylate.
Toru Tachihara and Takeshi Kitahara, Tetrahedron, 2003, 59, 1773-1780.
・ Synthesis and Odour Evaluation of Stereoisomers of N-Alkyl-pyrrolidine Derivatives,
Characteristic Roast Odour of Seafood.
Toru Tachihara, Susumu Ishizaki, Yoshiko Kurobayashi, Hiroshi Tamura, Youichi Ikemoto,
Atsushi Onuma and Takeshi Kitahara, Flavout. Fragr J., 2003, 18, 305-308.
・Synthetic Study on Indolic Enamides.
Kouji Kuramochi, Yuko Osada and Takeshi Kitahara, Tetrahedron, 2003, 59, 9447-9454.
・ Synthesis and Determination of the Absolute Configuration of Fudecalone
Hidenori Watanabe, Takahiro Yamaguchi, Takeshi Furuuchi, Masaru Kido, Masahiko Bando
and Takeshi Kitahara, ARKIVOC, 2003, 8, 267-282.
・Synthesis of Both Enantiomers of Brevioxime and Determination of Its Absolute Configuration.
Yutaka Nishimura, Ken Ishigami and Takeshi Kitahara, Heterocycles, 2003, 61, 481-491.
・Synthesis of the Racemate and Both Enantiomers of Massoilactone.
Masashi Ishikawa, Masayasu Amaike, Masamichi Itoh,, Yasuhiro Warita and Takeshi Kitahara,
Biosci. Biotechnol. Biochem., 2003, 67, 2210-2214.
・ Enantioselective Total Synthesis of Cineromycin B.
Tatsuhisa Takahashi, Hidenori Watanabe and Takeshi Kitahara, Tetrahedron Lett., 2003,
44, 9219-9222.
・ Determination of the Absolute Configuration of Hydroxynicotianamine, a Hypotensive
Component in Buckwheat.
Keisuke Yoshikawa, Hidenori Watanabe, Yasuo Aoyagi and Takeshi Kitahara, Heterocycles,
2003, 61, 481-491.
・ Analysis of Enantiomeric Ratios of Aroma Components in Several Flowers Using
"CHIRAMIX" Column.
Shigeyuki Tamogami, Ken-ichi Awano, Masayasu Amaike, Yoshikazu Takagi and
Takeshi Kitahara, Flavour Fragr. J., 2004, 19, 1-5.
・ ''Aqua-Space'', a New Headspace Method for Isolation of Natural Floral Aromas Using
Humidified Air as Carrier Gas.
Masashi Ishikawa, Toshio Honda, Yoshiko Kurobayashi, Akira Fujita and Takeshi Kitahara,
Biosci. Biotechnol. Biochem., 2004, 68, 454-457.
・Synthesis of All Stereoisomers of the Norchrysanthemic Acid Methyl Ester.
Kazuya Ujihara, Noritada Matsuo and Takeshi Kitahara, Synth. Commun., 2004,
34, 1001-1010.
・ Synthesis of Microcarpalide, a Microfilament Disrupting Agent.
Ken Ishigami and Takeshi Kitahara, Heterocycles, 2004, 63, 785-790.
・ Short Step Synthesis of Chenodiol from Stigmasterol.
Toru Uekawa, Ken Ishigami and Takeshi Kitahara, Biosci. Biotechnol. Biochem., 2004,
68, 1332-1337.
・Synthesis and odour evaluation of stereoisomers of N-alkyl-pyrrolidine derivatives,
characteristic roast odour of seafood.
T. Tachihara, S. Ishizaki, Y. Kurobayashi, H. Tamura, Y. Ikemoto, A. Onuma and
T. Kitahara, Flavour Fragr. J., 2004, 18, 305-308.
・ Biotransformation of a-Isomethylionone to 1-(2,6,6-Trimethyl-2-cyclohexen-
1-yl)propan-2-one.
S. Ishizaki, M. Itoh, T. Komai, T. Honda and T. Kitahara, Biosci. Biotechnol. Biochem.,
2004, 68, 2178-2182.
・ Analysis of Ambergris Tincture.
K. Awano, S. Ishizaki, O. Takazawa and T. Kitahara, Flavour Fragr. J., 2005, 20, 18-21.