Okamoto lab is looking for international graduate students!
- Master + PhD course: Department of Chemistry and Biotechnology **link**
- PhD course only: Department of Advanced Interdisciplinary Studies **link**
Knowledge and skills in synthetic chemistry are required. Okamoto strongly advises you to read his papers before contacting him by email.

'Biomolecular design': Borderless research between organic synthesis and life science
How are our bodies created from atoms and molecules? We systematically investigate how the atoms and building blocks of biopolymers (nucleic acids and proteins) participate in biological phenomena, introducing synthetic chemistry-based ideas into biological and genetic studies. Research in our group is concerned with diverse aspects of the design and function of biopolymers on an atomic scale. The focus is on the design, synthesis and physical properties of new, man-made biopolymers with various functions. Also included is the design of unprecedented organic chemical systems for recognizing, transforming and visualizing a single component or atom in biopolymers of interest. These researches are the fundamental studies reflecting the essence of life science on an atomic scale and the material-developing studies to get useful functional materials for the latest studies on life sciences and medical technologies. The lab employs a multidisciplinary approach involving organic synthesis, photophysical chemistry, state-of-the-art spectroscopy, and biological assays to address new approaches to the interface between synthetic chemistry and life science. Current projects include:

1. Visualizing the variable behavior of nucleic acid molecules in living cells
2. Catching the key of gene expression by developing target-specific chemical reactions
3. Creating new cellular function control system by synthesizing superbiopolymers containing unnatural nucleotides and amino acids
4. Designing stimuli-responsive chemical tools simply and precisely controlling biopolymers and living cells without denaturation and cytotoxicity

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Bioorganic Chemistry, Organic Synthesis, Photochemistry and Photobiology, Nucleic Acid Chemistry, Protein Engineering, In-Cell Organic Chemistry, Live Cell Imaging, Epigenetics, Hydrogel, Synthetic Biology, Design of Stimuli-sensitive Molecules, Cell Engineering