NanoBio First - Funding Program for World-Leading Innovative R&D on Science and Technology_[Development of Innovative Diagnostic and Therapeutic Systems Based on Nanobiotechnology] NanoBio First Japanese

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Article FY 2011

1. *T. Goda, Y. Miyahara, Thermo-responsive molecular switches for ATP using hairpin DNA aptamers, Biosens Bioelectron, 26, 3949-3952, 2011
2. *F. Pittella, M. Zhang, Y. Lee, H. Kim, T. Tockary, K. Osada, T. Ishii, K. Miyata, N. Nishiyama, K. Kataoka, Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity, Biomaterials, 32 (11) 3106-3114, 2011
3. *Y. Anraku, A. Kishimura, A. Kobayashi, M. Oba, K. Kataoka, Size-controlled long-circulating PICsome as ruler to measure critical cut-off disposition size into normal and tumor tissues, Chem. Commun, 47 (21) 6054-6056, 2011
4. *T. Nomoto, Y. Matsumoto, K. Miyata, M. Oba, S. Fukushima, N. Nishiyama, T. Yamasoba, K. Kataoka, In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning microscopy, J Control Release, 151 (2) 104-109, 2011
5.  *J.A. Autio, J. Kershaw, S. Shibata, T. Obata, I. Kanno, I. Aoki, High b-value diffusion-weighted fMRI in a rat forepaw electrostimulation model at 7 T, Neuroimage, 57 (1) 140-148, 2011
6. *T. Lai, K. Kataoka, G.S. Kwon, Pluronic-based cationic block copolymer for forming pDNA polyplexes with enhanced cellular uptake and improved transfection efficiency, Biomaterials, 32 (20) 4594-4603, 2011
7. *Y. Inaba, T. Moriyama, S. Yoshizawa, S. Umemura, Ultrasonic coagulation of large tissue region by generating multiple cavitation clouds in direction perpendicular to ultrasound propagation, Jpn J Appl Phys, 50, 07HF13, 2011
8.  *K. Kawabata, T. Maruoka, R. Asami, S. Umemura, Phase change nanodroplet (PCND) and microbubble generated from PCND as sources of chemically active cavitation, Jpn J Appl Phys, 50, 07HE06, 2011
9. *R. Bakalova, Z. Zhelev, D. Kokuryo, L. Spasov, I. Aoki, T. Saga, Chemical nature and structure of organic coating of quantum dots is crucial for their application in imaging diagnostics, Int J Nanomed, 6, 1719-1732, 2011
10. *R.J. Christie, K. Miyata, Y. Matsumoto, T. Nomoto, D. Menasco, T.C. Lai, M. Pennisi, K. Osada, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka, Effect of polymer structure on micelles formed between siRNA and cationic block copolymer Comprising thiols and amidines, Biomacromolecules, 12 (9) 3174-3185, 2011
11. *H. Uchida, K. Miyata, M. Oba, T. Ishii, T. Suma, K. Itaka, N. Nishiyama, K. Kataoka, Odd-even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles, J Am Chem Soc, 133 (39) 15524-15532, 2011
12. *Y. Saito, Y. Hashimoto, J. Kuroda, M. Yasunaga, Y. Koga, A .Takahashi, Y. Matsumura, The inhibition of pancreatic cancer invasion-metastasis cascade in both cellular signal and blood coagulation cascade of tissue factor by its neutralisation antibody, Eur J Cancer, 47, 2230-2239, 2011
13. *松本有, 野本貴大, 藤加珠子, 片岡一則, 生体内リアルタイム共焦点顕微鏡, Drug Delivery System, 26 (5) 535-539, 2011
14.  *M. Yasunaga, S. Manabe, D. Tarin, Y. Matsumura, Cancer-stroma targeting therapy by cytotoxic immunoconjugate bound to the collagen 4 network in the tumor tissue, Bioconjugate Chem, 22, 1776-1783, 2011
15. *K. Odaka, I. Aoki, J. Moriya, K. Tateno, H. Tadokoro, J. Kershaw, T. Minamino, T. Irie, T. Fukumura, I. Komuro, T. Saga, In vivo tracking of transplanted mononuclear cells using manganese-enhanced magnetic resonance imaging (MEMRI), PLoS One, 6 (10) e25487, 2011
16. *S. Uchida, K. Itaka, Q. Chen, K. Osada, K. Miyata, T. Ishii, M. Harada-Shiba, K. Kataoka, Combination of chondroitin sulfate and polyplex micelles from poly (ethylene glycol)-poly{N’-[N-(2-aminoethyl)-2-aminoethyl] aspartamide} block copolymer for prolonged in vivo gene transfection with reduced toxicity, J Control Release, 155 (2) 296-302, 2011
17. *Y. Yamamoto, Y. Yoshioka, K. Minoura, RU. Takahashi, F. Takeshita, T. Taya, R. Horii, Y. Fukuoka, T. Kato, N. Kosaka, T. Ochiya, An integrative genomic analysis revealed the relevance of microRNA and gene expression for drug-resistance in human breast cancer cells, Mol Cancer, 10 (135), 2011
18. *H. Lu, W. Syu, N. Nishiyama, K. Kataoka, P. Lai, Dendrimer phthalocyanine- encapsulated polymeric micelle-mediated photochemical internalization extends the efficacy of photodynamic therapy and overcome the drug-resistance in vivo, J Control Release, 155 (3) 458-464, 2011
19. *S. Herlambang, M. Kumagai, S. Horie, S. Fukushima, M. Oba, T. Nomoto, K. Miyazaki, Y. Morimoto, N. Nishiyama, K. Kataoka, Disulfide crosslinked polyion complex micelles encapsulating dendrimer phthalocyanine directed to improved efficiency of photodynamic therapy, J Control Release, 155 (3) 449-457, 2011
20. *M. Haneoka, Y. Shirasaki, H. Sugino, T. Aoki, T. Arakawa, K. Ozaki, D. H. Yoon, N. Ishii, R. Iizuka,  S. Shoji, T. Funatsu, Microfluidic active sorting of DNA molecules labeled with single quantum dots using flow switching by a hydrogel sol-gel transition, Sensor Actuat B-Chem, 159, 314-320, 2011
21.  *J. Zhang, K. Okabe, T. Tani, T. Funatsu, Dynamic association-dissociation and harboring of endogenous mRNAs in stress granules, J Cell Sci, 124, 4087-4095, 2011
22. *S. Choi, J. Lee, K. Igawa, S. Suzuki, M. Mochizuki, R. Nishimura, U. Chung, N. Sasaki, Effect of trehalose coating on basic fibroblast growth factor release from tailor-made bone implants, J Vet Med Sci, 73 (12) 1547-52, 2011
23.  *A. Iriyama, T. Usui, Y. Yanagi, S. Amano, M. Oba, K. Miyata, N. Nishiyama, K. Kataoka, Gene transfer using micellar nanovectors inhibits corneal neovascularization in vivo, Cornea, 30 (12) 1423-1427, 2011
24.  *A. Iriyama, M. Oba, T. Ishii, N. Nishiyama, K. Kataoka, Y. Tamaki, Y. Yanagi, Gene transfer using micellar nanovectors inhibits choroidal neovascularization in vivo, PLoS One, 6 (12) e28560, 2011
25. *F. M. Mickler, Y. Vachutinsky, M. Oba, K. Miyata, N. Nishiyama, K. Kataoka, C. Brachle, N. Ruthardt, Effect of integrin targeting and PEG shielding on polyplex micelle internalization studied by live-cell imaging, J Control Release, 156 (3) 364-373, 2011
26.  *K. Osada, T. Shiotani, T. A. Tockary, D. Kobayashi, H. Oshima, S. Ikeda, R. J. Christie, K. Itaka,  K. Kataoka, Enhanced gene expression promoted by the quantized folding of pDNA within polyplex micelles, Biomaterials, 33 (1) 325-332, 2012
27. *H. Cabral, Y. Matsumoto, K. Mizuno, Q. Chen, M. Murakami, M. Kimura, Y. Terada, M. R. Kano, K. Miyazono, M. Uesaka, N. Nishiyama, K. Kataoka, Accumulation of sub-100nm polymeric micelles in poorly permeable tumours depends on size, Nat Nanotechnol, 6 (12) 815-823, 2011

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- Development of Innovative Diagnostic and Therapeutic Systems Based on Nanobiotechnology

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