Study on DNA sequencing devices for microRNA
DNA sequencing analysis is expected to be applied for precise detection of microRNA as a biomarker of disieses such as cancer. In this study, DNA sequencing devices will be developed combining semiconductor technology and electrochemical detection methodology.Nucleic acid probes are immobilized on the surface of electrochemical electrodes and signals of single-base extensions are detected electrochemically for microRNA analysis. This method would be suitable for a simple and miniaturized testing system in clinical diagnostics.
|Affiliation||The Institute of Biomaterials and Biongineering,
Tokyo Medical and Dental University
|Address||2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062 Japan|