Score E
Sequences producing significant alignments: (bits) Value
gb|AA402146.1|AA402146 zu55d05.r1 Soares ovary tumor NbHOT ... 260 2e-68
gb|AW673686.1|AW673686 ba56g03.y3 NIH_MGC_10 Homo sapiens c... 242 5e-63
gb|AA180513.1|AA180513 zp53f05.r1 Stratagene NT2 neuronal p... 200 2e-50
gb|AW732678.1|AW732678 bb11b02.y1 NIH_MGC_8 Homo sapiens cD... 188 1e-49
gb|AW248240.1|AW248240 2819820.5prime NIH_MGC_7 Homo sapien... 189 4e-47
gb|AW405156.1|AW405156 UI-HF-BL0-acl-f-12-0-UI.r1 NIH_MGC_3... 186 4e-46
gb|AW404509.1|AW404509 UI-HF-BL0-aby-a-08-0-UI.r1 NIH_MGC_3... 181 1e-44
gb|AI268786.1|AI268786 qo40e04.x1 NCI_CGAP_Lu5 Homo sapiens... 181 1e-44
gb|R17846.1|R17846 yg09h05.r1 Soares infant brain 1NIB Homo... 180 2e-44
gb|AA071261.1|AA071261 zm73d07.r1 Stratagene neuroepitheliu... 144 4e-44
gb|AA305221.1|AA305221 EST176233 Colon carcinoma (Caco-2) c... 175 1e-42
gb|AI912761.1|AI912761 we13d06.x1 NCI_CGAP_Lu24 Homo sapien... 170 2e-41
gb|AI379894.1|AI379894 tc64g11.x1 Soares_NhHMPu_S1 Homo sap... 169 4e-41
gb|AA216564.1|AA216564 zq94b03.r1 Stratagene NT2 neuronal p... 139 3e-39
gb|AA150608.1|AA150608 zl46f03.r1 Soares_pregnant_uterus_Nb... 162 4e-39
emb|AL121040.1|AL121040 DKFZp762O243_r1 762 (synonym: hmel2... 159 5e-38
gb|T08405.1|T08405 EST06296 Infant Brain, Bento Soares Homo... 157 2e-37
gb|AA150079.1|AA150079 zl41e05.r1 Soares_pregnant_uterus_Nb... 155 7e-37
gb|AW845225.1|AW845225 CM0-CT0013-290699-017-h06 CT0013 Hom... 153 2e-36
gb|AI422808.1|AI422808 tf22f09.x1 NCI_CGAP_Brn23 Homo sapie... 149 4e-35
gb|AW963738.1|AW963738 EST375811 MAGE resequences, MAGH Hom... 149 5e-35
gb|AA356305.1|AA356305 EST64852 Jurkat T-cells VI Homo sapi... 149 5e-35
gb|AA355941.1|AA355941 EST64416 Jurkat T-cells VI Homo sapi... 147 2e-34
gb|AW352006.1|AW352006 RC0-HT0107-150999-001-E12 HT0107 Hom... 147 2e-34
gb|W32458.1|W32458 zc67e01.r1 Soares_fetal_heart_NbHH19W Ho... 147 2e-34
gb|AA305930.1|AA305930 EST176989 Jurkat T-cells VI Homo sap... 145 6e-34
gb|AA313596.1|AA313596 EST185538 Colon carcinoma (HCC) cell... 145 8e-34
gb|R72692.1|R72692 yj93f04.r1 Soares breast 2NbHBst Homo sa... 145 8e-34
gb|AI032256.1|AI032256 or97c07.s1 NCI_CGAP_Lu5 Homo sapiens... 144 1e-33
gb|AI950375.1|AI950375 wp10e11.x1 NCI_CGAP_Kid12 Homo sapie... 143 3e-33
gb|AW406812.1|AW406812 UI-HF-BL0-acz-h-02-0-UI.r1 NIH_MGC_3... 143 4e-33
gb|AI954176.1|AI954176 wx80f10.x1 NCI_CGAP_Ov38 Homo sapien... 141 2e-32
gb|AI671999.1|AI671999 wb72c09.x1 NCI_CGAP_GC6 Homo sapiens... 141 2e-32
gb|AA306172.1|AA306172 EST177213 Jurkat T-cells VI Homo sap... 141 2e-32
gb|AI096507.1|AI096507 qa04c05.x1 NCI_CGAP_Brn23 Homo sapie... 129 2e-32
gb|AW505106.1|AW505106 UI-HF-BN0-als-d-05-0-UI.r1 NIH_MGC_5... 139 4e-32
gb|BE173604.1|BE173604 RC2-HT0560-290200-014-h07 HT0560 Hom... 138 1e-31
gb|AA310185.1|AA310185 EST181084 Jurkat T-cells V Homo sapi... 137 2e-31
gb|AA490696.1|AA490696 aa45c03.r1 Soares_NhHMPu_S1 Homo sap... 91 1e-30
gb|AA205640.1|AA205640 zq67g11.r1 Stratagene neuroepitheliu... 134 1e-30
gb|AA781342.1|AA781342 aj25a10.s1 Soares_testis_NHT Homo sa... 134 1e-30
gb|AA429005.1|AA429005 zv78b03.r1 Soares_total_fetus_Nb2HF8... 133 3e-30
gb|AA909637.1|AA909637 ol09f10.s1 Soares_NFL_T_GBC_S1 Homo ... 133 3e-30
gb|AI417816.1|AI417816 tg71g01.x1 Soares_NhHMPu_S1 Homo sap... 131 1e-29
gb|AA312049.1|AA312049 EST182768 Jurkat T-cells VI Homo sap... 120 1e-29
gb|AI557695.1|AI557695 pt2.1-2.F05.r tumor2 Homo sapiens cD... 130 3e-29
gb|AW630963.1|AW630963 hh90a06.y1 NCI_CGAP_GU1 Homo sapiens... 130 3e-29
gb|AA160643.1|AA160643 zq49b11.r1 Stratagene hNT neuron (#9... 129 5e-29
gb|AA312367.1|AA312367 EST183041 Jurkat T-cells VI Homo sap... 123 2e-28
gb|AA205618.1|AA205618 zq67h10.r1 Stratagene neuroepitheliu... 119 4e-26
Alignments
>gb|AA402146.1|AA402146 zu55d05.r1 Soares ovary tumor NbHOT Homo sapiens cDNA clone
IMAGE:741897 5' similar to gb:X70848 PROTEIN PHOSPHATASE
PP1-ALPHA 1 CATALYTIC SUBUNIT (HUMAN);.
Length = 656
Score = 260 bits (658), Expect = 2e-68
Identities = 116/215 (53%), Positives = 152/215 (69%)
Frame = +1
Query: 41 KSVFASQASLLEVEPPIIVCGDIHGQYSDLLRIFDKNGFPPDVNFLFLGDYVDRGRQNIE 100
+ +F SQ LLE+E P+ +CGDIHGQY DLLR+F+ GFPP+ N+LF GDYVDRG+Q++E
Sbjct: 13 REIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFPGDYVDRGKQSLE 192
Query: 101 TICLMLCFKIKYPENFFMLRGNHECPAINRVYGFYEECNRRYKSTRLWSIFQDTFNWMPL 160
TICL+L +KIKYPENFF+LRGN C +INR+YGFY+EC RRY + +LW F D FN +P+
Sbjct: 193 TICLLLAYKIKYPENFFLLRGNQXCASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPI 369
Query: 161 CGLIGSRILCMHGGLSPHXXXXXXXXXXXXXXXXXNPSIGIDLLWADPDQWVKGWQANTR 220
++ +I C HGGLSP + + DLLW+DPD+ V+GW N R
Sbjct: 370 AAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDR 549
Query: 221 GVSYVFGQDVVADVCSRLDIDLVARAHQVVQDGYE 255
GVS+ FG +VVA + D+DL+ RAHQVV+DGYE
Sbjct: 550 GVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYE 654
>gb|AW673686.1|AW673686 ba56g03.y3 NIH_MGC_10 Homo sapiens cDNA clone IMAGE:2900596 5'
similar to gb:L07395 PROTEIN PHOSPHATASE PP1-GAMMA
CATALYTIC SUBUNIT (HUMAN); gb:M27071 Mus musculus
protein phosphatase type 1 (MOUSE);.
Length = 587
Score = 242 bits (611), Expect = 5e-63
Identities = 108/195 (55%), Positives = 139/195 (70%)
Frame = +1
Query: 66 QYSDLLRIFDKNGFPPDVNFLFLGDYVDRGRQNIETICLMLCFKIKYPENFFMLRGNHEC 125
QY DLLR+F+ GFPP+ N+LFLGDYVDRG+Q++ETICL+L +KIKYPENFF+LRGNHEC
Sbjct: 1 QYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHEC 180
Query: 126 PAINRVYGFYEECNRRYKSTRLWSIFQDTFNWMPLCGLIGSRILCMHGGLSPHXXXXXXX 185
+INR+YGFY+EC RRY + +LW F D FN +P+ ++ +I C HGGLSP
Sbjct: 181 ASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQI 357
Query: 186 XXXXXXXXXXNPSIGIDLLWADPDQWVKGWQANTRGVSYVFGQDVVADVCSRLDIDLVAR 245
+ + DLLW+DPD+ V GW N RGVS+ FG +VVA + D+DL+ R
Sbjct: 358 RRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKYHHKHDVDLICR 537
Query: 246 AHQVVQDGYEFFASK 260
AHQVV+DGYEFFA +
Sbjct: 538 AHQVVEDGYEFFAKR 582
>gb|AA180513.1|AA180513 zp53f05.r1 Stratagene NT2 neuronal precursor 937230 Homo sapiens
cDNA clone IMAGE:613185 5' similar to gb:L07395 PROTEIN
PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT (HUMAN);.
Length = 469
Score = 200 bits (504), Expect = 2e-50
Identities = 86/157 (54%), Positives = 112/157 (70%)
Frame = +2
Query: 52 EVEPPIIVCGDIHGQYSDLLRIFDKNGFPPDVNFLFLGDYVDRGRQNIETICLMLCFKIK 111
E+E P+ +CGDIHGQY DLLR+F+ GFPP+ N+LFLGDYVDRG+Q++ETICL+L +KIK
Sbjct: 2 ELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIK 181
Query: 112 YPENFFMLRGNHECPAINRVYGFYEECNRRYKSTRLWSIFQDTFNWMPLCGLIGSRILCM 171
YPENFF+LRGNHEC +INR+YGFY+EC RRY + +LW F D FN +P+ ++ +I C
Sbjct: 182 YPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCC 358
Query: 172 HGGLSPHXXXXXXXXXXXXXXXXXNPSIGIDLLWADP 208
HGGLSP + + DLLW+ P
Sbjct: 359 HGGLSPDLQSMEQIRRIMRPTDVPDQGLPCDLLWSXP 469
>gb|AW732678.1|AW732678 bb11b02.y1 NIH_MGC_8 Homo sapiens cDNA clone IMAGE:2959083 5'
similar to gb:X70848 PROTEIN PHOSPHATASE PP1-ALPHA 1
CATALYTIC SUBUNIT (HUMAN); gb:M27071 Mus musculus
protein phosphatase type 1 (MOUSE);.
Length = 616
Score = 188 bits (473), Expect(2) = 1e-49
Identities = 78/125 (62%), Positives = 102/125 (81%)
Frame = +1
Query: 53 VEPPIIVCGDIHGQYSDLLRIFDKNGFPPDVNFLFLGDYVDRGRQNIETICLMLCFKIKY 112
+E P+ +CGDIHGQY DLLR+F+ GFPP+ N+LFLGDYVDRG+Q++ETICL+L +KIKY
Sbjct: 172 LEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKY 351
Query: 113 PENFFMLRGNHECPAINRVYGFYEECNRRYKSTRLWSIFQDTFNWMPLCGLIGSRILCMH 172
PENFF+LRGNH+C +INR+YGFY+EC RRY + +LW F D FN +P+ ++ +I C H
Sbjct: 352 PENFFLLRGNHKCASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCH 528
Query: 173 GGLSP 177
G LSP
Sbjct: 529 GCLSP 543
Score = 31.3 bits (69), Expect(2) = 1e-49
Identities = 15/48 (31%), Positives = 27/48 (56%)
Frame = +3
Query: 5 MDVDNLMSRLLNVGMSGGRLTTSVNEQELQTCCAVAKSVFASQASLLE 52
+++D+++ RLL V S + E E++ C ++ +F SQ LLE
Sbjct: 27 LNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLE 170
>gb|AW248240.1|AW248240 2819820.5prime NIH_MGC_7 Homo sapiens cDNA clone IMAGE:2819820 5'.
Length = 459
Score = 189 bits (475), Expect = 4e-47
Identities = 82/150 (54%), Positives = 106/150 (70%)
Frame = +3
Query: 78 GFPPDVNFLFLGDYVDRGRQNIETICLMLCFKIKYPENFFMLRGNHECPAINRVYGFYEE 137
GFPP+ N+LFLGDYVDRG+Q++ETICL+L +KIKYPENFF+LRGNHEC +INR+YGFY+E
Sbjct: 9 GFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDE 188
Query: 138 CNRRYKSTRLWSIFQDTFNWMPLCGLIGSRILCMHGGLSPHXXXXXXXXXXXXXXXXXNP 197
C RRY + +LW F D FN +P+ ++ +I C HGGLSP +
Sbjct: 189 CKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQ 365
Query: 198 SIGIDLLWADPDQWVKGWQANTRGVSYVFG 227
+ DLLW+DPD+ V+GW N RGVS+ FG
Sbjct: 366 GLLCDLLWSDPDKDVQGWGENDRGVSFTFG 455
>gb|AW405156.1|AW405156 UI-HF-BL0-acl-f-12-0-UI.r1 NIH_MGC_37 Homo sapiens cDNA clone
IMAGE:3059494 5'.
Length = 510
Score = 186 bits (467), Expect = 4e-46
Identities = 80/138 (57%), Positives = 108/138 (77%)
Frame = +2
Query: 5 MDVDNLMSRLLNVGMSGGRLTTSVNEQELQTCCAVAKSVFASQASLLEVEPPIIVCGDIH 64
+++D+++ RLL V S + E E++ C ++ +F SQ LLE+E P+ +CGDIH
Sbjct: 89 LNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIH 268
Query: 65 GQYSDLLRIFDKNGFPPDVNFLFLGDYVDRGRQNIETICLMLCFKIKYPENFFMLRGNHE 124
GQY DLLR+F+ GFPP+ N+LFLGDYVDRG+Q++ETICL+L +KIKYPENFF+LRGNHE
Sbjct: 269 GQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHE 448
Query: 125 CPAINRVYGFYEECNRRY 142
C +INR+YGFY+EC RRY
Sbjct: 449 CASINRIYGFYDECKRRY 502
>gb|AW404509.1|AW404509 UI-HF-BL0-aby-a-08-0-UI.r1 NIH_MGC_37 Homo sapiens cDNA clone
IMAGE:3058071 5'.
Length = 419
Score = 181 bits (454), Expect = 1e-44
Identities = 79/132 (59%), Positives = 102/132 (76%)
Frame = +1
Query: 11 MSRLLNVGMSGGRLTTSVNEQELQTCCAVAKSVFASQASLLEVEPPIIVCGDIHGQYSDL 70
+ RLL V S + E E++ C ++ +F SQ LLE+E P+ +CGDIHGQY DL
Sbjct: 13 IGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDL 192
Query: 71 LRIFDKNGFPPDVNFLFLGDYVDRGRQNIETICLMLCFKIKYPENFFMLRGNHECPAINR 130
LR+F+ GFPP+ N+LFLGDYVDRG+Q++ETICL+L +KIKYPENFF+LRGNHEC +INR
Sbjct: 193 LRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINR 372
Query: 131 VYGFYEECNRRY 142
+YGFY+EC RRY
Sbjct: 373 IYGFYDECKRRY 408
>gb|AI268786.1|AI268786 qo40e04.x1 NCI_CGAP_Lu5 Homo sapiens cDNA clone IMAGE:1911006 3'
similar to gb:X70848 PROTEIN PHOSPHATASE PP1-ALPHA 1
CATALYTIC SUBUNIT (HUMAN);.
Length = 421
Score = 181 bits (454), Expect = 1e-44
Identities = 78/137 (56%), Positives = 106/137 (76%)
Frame = +1
Query: 5 MDVDNLMSRLLNVGMSGGRLTTSVNEQELQTCCAVAKSVFASQASLLEVEPPIIVCGDIH 64
+++D+++ RLL V S + E E++ C ++ +F SQ LLE+E P+ +CGDIH
Sbjct: 10 LNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIH 189
Query: 65 GQYSDLLRIFDKNGFPPDVNFLFLGDYVDRGRQNIETICLMLCFKIKYPENFFMLRGNHE 124
GQY DLLR+F+ GFPP+ N+LFLGDYVDRG+Q++ETICL+L +KIKYPENFF+LRGNHE
Sbjct: 190 GQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHE 369
Query: 125 CPAINRVYGFYEECNRR 141
C +INR+YGFY+EC R
Sbjct: 370 CASINRIYGFYDECKSR 420
>gb|R17846.1|R17846 yg09h05.r1 Soares infant brain 1NIB Homo sapiens cDNA clone
IMAGE:31988 5' similar to gb:X70848 PROTEIN PHOSPHATASE
PP1-ALPHA 1 CATALYTIC SUBUNIT (HUMAN);.
Length = 463
Score = 180 bits (452), Expect = 2e-44
Identities = 77/128 (60%), Positives = 101/128 (78%)
Frame = +2
Query: 28 VNEQELQTCCAVAKSVFASQASLLEVEPPIIVCGDIHGQYSDLLRIFDKNGFPPDVNFLF 87
+ E E++ C ++ +F SQ LLE+E P+ +CGDIHGQY DLLR+F+ GFPP+ N+LF
Sbjct: 35 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 214
Query: 88 LGDYVDRGRQNIETICLMLCFKIKYPENFFMLRGNHECPAINRVYGFYEECNRRYKSTRL 147
LGDYVDRG+Q++ETICL+L +KIKYPENFF+LRGN C +INR+YGFY+EC RRY + +L
Sbjct: 215 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNQSCASINRIYGFYDECKRRY-NIKL 391
Query: 148 WSIFQDTF 155
W F D F
Sbjct: 392 WKTFTDCF 415
>gb|AA071261.1|AA071261 zm73d07.r1 Stratagene neuroepithelium (#937231) Homo sapiens cDNA
clone IMAGE:531277 5' similar to gb:X70848 PROTEIN
PHOSPHATASE PP1-ALPHA 1 CATALYTIC SUBUNIT (HUMAN);.
Length = 474
Score = 144 bits (359), Expect(2) = 4e-44
Identities = 61/97 (62%), Positives = 80/97 (81%)
Frame = +3
Query: 28 VNEQELQTCCAVAKSVFASQASLLEVEPPIIVCGDIHGQYSDLLRIFDKNGFPPDVNFLF 87
+ E E++ C ++ +F SQ LLE+E P+ +CGDIHGQY DLLR+F+ GFPP+ N+LF
Sbjct: 39 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 218
Query: 88 LGDYVDRGRQNIETICLMLCFKIKYPENFFMLRGNHE 124
LGDYVDRG+Q++ETICL+L +KIKYPENFF+LRGNHE
Sbjct: 219 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHE 329
Score = 57.0 bits (135), Expect(2) = 4e-44
Identities = 22/47 (46%), Positives = 32/47 (67%)
Frame = +1
Query: 121 GNHECPAINRVYGFYEECNRRYKSTRLWSIFQDTFNWMPLCGLIGSR 167
G +C +INR+YGFY+EC RRY + +LW F D FN +P+ ++ R
Sbjct: 319 GTTKCASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDER 456
Database: GenBank Human EST entries
Posted date: Jul 9, 2000 8:11 PM
Number of letters in database: 800,131,619
Number of sequences in database: 2,121,173
Lambda K H
0.325 0.140 0.451
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 339884924
Number of Sequences: 2121173
Number of extensions: 4845011
Number of successful extensions: 25010
Number of sequences better than 10.0: 594
Number of HSP's better than 10.0 without gapping: 568
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 24284
Number of HSP's gapped (non-prelim): 621
length of query: 305
length of database: 266,710,539
effective HSP length: 49
effective length of query: 256
effective length of database: 162,773,062
effective search space: 41669903872
effective search space used: 41669903872
frameshift window, decay const: 50, 0.1
T: 13
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.6 bits)
S2: 71 (32.1 bits)
