Score E
Sequences producing significant alignments: (bits) Value
pir||T20526 hypothetical protein F07A11.2 - Caenorhabditis ... 1423 0.0
pir||T21230 hypothetical protein F22B3.4 - Caenorhabditis e... 1253 0.0
gb|AAF45333.1| (AE003355) Gfat gene product [Drosophila mel... 840 0.0
emb|CAB46365.1| (Y18628) glucosamine--fructose-6-phosphate ... 839 0.0
gb|AAF56785.1| (AE003765) CG1345 gene product [Drosophila m... 830 0.0
ref|NP_038556.1| glutamine fructose-6-phosphate transaminas... 803 0.0
ref|NP_002047.1| glucosamine-fructose-6-phosphate aminotran... 799 0.0
ref|NP_038557.1| glutamine fructose-6-phosphate transaminas... 795 0.0
ref|NP_005101.1| glutamine-fructose-6-phosphate transaminas... 790 0.0
sp|P53704|GFA1_CANAL GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 701 0.0
ref|NP_012818.1| Glutamine_fructose-6-phosphate amidotransf... 690 0.0
gb|AAA34643.1| (J04719) D-fructose-6-phosphate amidotransfe... 679 0.0
sp|Q09740|GFA1_SCHPO PUTATIVE GLUCOSAMINE--FRUCTOSE-6-PHOSP... 655 0.0
pir||S54460 hypothetical protein YMR085w - yeast (Saccharom... 349 5e-95
ref|NP_013802.1| Ymr085wp 349 5e-95
sp|O66648|GLMS_AQUAE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 299 5e-80
pir||A75536 glucosamine--fructose-6-phosphate aminotransfer... 281 1e-74
sp|P44708|GLMS_HAEIN GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 271 1e-71
sp|P17169|GLMS_ECOLI GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 270 3e-71
emb|CAA25785.1| (X01631) gluS protein [Escherichia coli] 269 6e-71
gb|AAA62080.1| (L10328) glutamine amidotransferase [Escheri... 268 1e-70
emb|CAB87226.1| (AL163641) glucosamine-fructose-6-phosphate... 266 7e-70
emb|CAB83584.1| (AL162752) glucosamine--fructose-6-phosphat... 264 3e-69
sp|Q56213|GLMS_THETH GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 263 3e-69
gb|AAF40502.1| (AE002361) glucosamine--fructose-6-phosphate... 263 6e-69
pir||F75212 glucosamine--fructose-6-phosphate aminotransfer... 261 1e-68
dbj|BAA86263.1| (AB023785) ORF3 [Streptomyces griseus] 260 4e-68
sp|Q9WXZ5|GLMS_THEMA GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 257 2e-67
sp|P08633|NODM_RHILV GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 254 3e-66
sp|O86781|GLMS_STRCO GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 253 4e-66
sp|O68956|GLMS_MYCSM GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 252 6e-66
pdb|1MOS|A Chain A, Isomerase Domain Of Glucosamine 6-Phosp... 252 1e-65
sp|P40831|GLMS_MYCLE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 250 2e-65
pir||D71248 probable glutamine--fructose-6-phosphate aminot... 250 4e-65
sp|O57981|GLMS_PYRHO GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 250 4e-65
emb|CAA04007.1| (AJ000333) glmS [Mycobacterium tuberculosis] 248 2e-64
sp|O06253|GLMS_MYCTU GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 248 2e-64
sp|Q56275|GLMS_THIFE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 240 3e-62
sp|O26273|GLMS_METTH GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 239 8e-62
sp|O83833|GLMS_TREPA GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 235 1e-60
sp|O68280|GLMS_NOSS9 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 232 1e-59
sp|P72720|GLMS_SYNY3 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 224 3e-57
sp|P25195|NODM_RHIME GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 222 7e-57
pir||T17590 probable glutamine--fructose-6-phosphate transa... 221 2e-56
gb|AAF39075.1| (AE002287) glucosamine--fructose-6-phosphate... 211 2e-53
sp|O84823|GLMS_CHLTR GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 206 8e-52
sp|P94323|NODM_BRAJA GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 205 1e-51
sp|P39754|GLMS_BACSU GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMIN... 203 7e-51
pir||T11976 L-glutamine-D-fructose-6-phosphate amidotransfe... 203 7e-51
ref|NP_013801.1| Ymr084wp >gi|1078584|pir||S54459 hypotheti... 202 9e-51
Alignments
>pir||T20526 hypothetical protein F07A11.2 - Caenorhabditis elegans
emb|CAA91315.1| (Z66511) similar to glucosamine-fructose-6-phosphate
aminotransferase~cDNA EST CEMSG96F comes from this
gene~cDNA EST EMBL:D75234 comes from this gene~cDNA EST
EMBL:D74893 comes from this gene~cDNA EST EMBL:D66539
comes from this gene~cDNA EST EMBL:D68>
Length = 725
Score = 1423 bits (3642), Expect = 0.0
Identities = 712/725 (98%), Positives = 712/725 (98%)
Query: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK 60
MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK
Sbjct: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK 60
Query: 61 AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV 120
AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV
Sbjct: 61 AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV 120
Query: 121 HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLEG 180
HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLEG
Sbjct: 121 HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLEG 180
Query: 181 AFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQTDGR 240
AFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQTDGR
Sbjct: 181 AFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQTDGR 240
Query: 241 RFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWEVEY 300
RFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWEVEY
Sbjct: 241 RFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWEVEY 300
Query: 301 FVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEMELQEI 360
FVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEMELQEI
Sbjct: 301 FVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEMELQEI 360
Query: 361 MKGSFKTYMQKEIFEQPDSVVNTMRGRVLPSGQVVLGGIKEYLPDIKRCRRLIMVACGTS 420
MKGSFKTYMQKEIFEQPDSVVNTMRGRVLPSGQVVLGGIKEYLPDIKRCRRLIMVACGTS
Sbjct: 361 MKGSFKTYMQKEIFEQPDSVVNTMRGRVLPSGQVVLGGIKEYLPDIKRCRRLIMVACGTS 420
Query: 421 YHSAIACRQIXXXXXXXXXXXXXASDFLDRETPIFRDDVCLFISQSGETADTLLALRYCK 480
YHSAIACRQI ASDFLDRETPIFRDDVCLFISQSGETADTLLALRYCK
Sbjct: 421 YHSAIACRQILEELSELPVVVELASDFLDRETPIFRDDVCLFISQSGETADTLLALRYCK 480
Query: 481 PRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLSDDRI 540
PRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLSDDRI
Sbjct: 481 PRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLSDDRI 540
Query: 541 SMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATCLEGAL 600
SMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATCLEGAL
Sbjct: 541 SMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATCLEGAL 600
Query: 601 KIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARKGAPI 660
KIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARKGAPI
Sbjct: 601 KIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARKGAPI 660
Query: 661 IIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAK 720
IIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAK
Sbjct: 661 IIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAK 720
Query: 721 SVTVE 725
SVTVE
Sbjct: 721 SVTVE 725
>pir||T21230 hypothetical protein F22B3.4 - Caenorhabditis elegans
emb|CAA92735.1| (Z68336) predicted using Genefinder~Similarity to Human
glucosamin-fructose-6-phosphate aminotransferase
(SW:GFAT_HUMAN)~cDNA EST EMBL:Z14705 comes from this
gene~cDNA EST EMBL:D32748 comes from this gene~cDNA EST
EMBL:D35477 comes from this gene~cDNA >
Length = 710
Score = 1253 bits (3206), Expect = 0.0
Identities = 627/725 (86%), Positives = 672/725 (92%), Gaps = 15/725 (2%)
Query: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK 60
MCGIFAYLNFL PKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSN+IE+PHS +ALLRK
Sbjct: 1 MCGIFAYLNFLAPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNDIENPHSKIALLRK 60
Query: 61 AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV 120
GKVSVL+D+IKE++ L+MDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSND NEFLVV
Sbjct: 61 RGKVSVLNDYIKENNEKLNMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDNNEFLVV 120
Query: 121 HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLEG 180
HNGIITNYREIKEYLEKKGHKFESETDTEVIAKL QH+HDRYPDFSFRQLVETVIQQLEG
Sbjct: 121 HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLTQHVHDRYPDFSFRQLVETVIQQLEG 180
Query: 181 AFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQTDGR 240
AFALAFKSSRFPGQLVASRRGSPLLVGIKSNS L T+HFPVS+SK GR
Sbjct: 181 AFALAFKSSRFPGQLVASRRGSPLLVGIKSNSTLHTSHFPVSYSK-------------GR 227
Query: 241 RFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWEVEY 300
FMSN+ATHLR+ETSFVETPNNILDLSIAVR+ +GSAK+ ++STT RPFDS D+EVEY
Sbjct: 228 CFMSNNATHLREETSFVETPNNILDLSIAVRNPSGSAKLPDNNSTT--RPFDSTDFEVEY 285
Query: 301 FVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEMELQEI 360
F+ASDAAAIIEHTKQVLFLEDDDVAFVEDG+LTIHRISRHAD+GEQKREV+LLE+E+QEI
Sbjct: 286 FIASDAAAIIEHTKQVLFLEDDDVAFVEDGSLTIHRISRHADSGEQKREVQLLELEIQEI 345
Query: 361 MKGSFKTYMQKEIFEQPDSVVNTMRGRVLPSGQVVLGGIKEYLPDIKRCRRLIMVACGTS 420
MKGS+KT+MQKEIFEQP+SVVNTMRGRVLPSGQVVLGG+KEYLP IKRCRRLIMVACGTS
Sbjct: 346 MKGSYKTFMQKEIFEQPESVVNTMRGRVLPSGQVVLGGLKEYLPAIKRCRRLIMVACGTS 405
Query: 421 YHSAIACRQIXXXXXXXXXXXXXASDFLDRETPIFRDDVCLFISQSGETADTLLALRYCK 480
YHSAIACRQ+ ASDFLDRETPIFR+DVCLFISQSGETADTL+ALRYCK
Sbjct: 406 YHSAIACRQVLEELSELPVVVELASDFLDRETPIFRNDVCLFISQSGETADTLMALRYCK 465
Query: 481 PRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLSDDRI 540
PRGALTIGVTNTVGSSI RESHCGIHINAGPEIGVASTKAYTSQI+SLL+FALT+S+DRI
Sbjct: 466 PRGALTIGVTNTVGSSIGRESHCGIHINAGPEIGVASTKAYTSQIVSLLLFALTISEDRI 525
Query: 541 SMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATCLEGAL 600
S KRR EIIDALN+LP LIR+VL LD++VL IA+QIYK+KSLLIMGRGLNFATCLEGAL
Sbjct: 526 SKMKRRAEIIDALNNLPILIRDVLDLDDQVLKIAEQIYKDKSLLIMGRGLNFATCLEGAL 585
Query: 601 KIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARKGAPI 660
KIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCND VYKKSLNALQQVVARKGAPI
Sbjct: 586 KIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDHVYKKSLNALQQVVARKGAPI 645
Query: 661 IIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAK 720
IIAD +VPE DLAGMKH+LRVP+TVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAK
Sbjct: 646 IIADSSVPESDLAGMKHVLRVPRTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAK 705
Query: 721 SVTVE 725
SVTVE
Sbjct: 706 SVTVE 710
>gb|AAF45333.1| (AE003355) Gfat gene product [Drosophila melanogaster]
Length = 694
Score = 840 bits (2147), Expect = 0.0
Identities = 426/726 (58%), Positives = 535/726 (73%), Gaps = 33/726 (4%)
Query: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK 60
MCGIFAYLN+LTPK R E++D+LV GL+R+EYRGYDS G+AID + + ++ ++++
Sbjct: 1 MCGIFAYLNYLTPKSRQEVLDLLVTGLKRLEYRGYDSTGVAIDSPD-----NKNIVMVKR 55
Query: 61 AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV 120
GKV VL + I+E S + H GIAHTRWATHG P + NSHPHRS+D+N F+VV
Sbjct: 56 TGKVKVLEEAIQEHFSGREYSEPVLTHVGIAHTRWATHGVPCEKNSHPHRSDDENGFVVV 115
Query: 121 HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLEG 180
HNGIITNY ++K +L K+G++FES+TDTEV AKL H+ +P +SFR+LVE I Q+EG
Sbjct: 116 HNGIITNYNDVKTFLSKRGYEFESDTDTEVFAKLVHHLWKTHPTYSFRELVEQAILQVEG 175
Query: 181 AFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQTDGR 240
AFA+A KS FPG+ VASRR SPLLVGIK+ +RL T+H P+ + KD D+K +
Sbjct: 176 AFAIAVKSKYFPGECVASRRSSPLLVGIKTKTRLATDHIPILYGKD------DKKLCTDQ 229
Query: 241 RFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWEVEY 300
S +R E P + S+ST+ P + EVEY
Sbjct: 230 DADSGKPQDIRPHGQSRELP-----------------VLPRSESTSEFMPLEEK--EVEY 270
Query: 301 FVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEMELQEI 360
F ASDA+A+IEHT +V++LEDDDVA V DG L+IHR+ + D+ RE+ L+ME+Q+I
Sbjct: 271 FFASDASAVIEHTNRVIYLEDDDVAAVRDGTLSIHRLKKSLDD-PHAREITTLKMEIQQI 329
Query: 361 MKGSFKTYMQKEIFEQPDSVVNTMRGRVLPSGQ-VVLGGIKEYLPDIKRCRRLIMVACGT 419
MKG++ +MQKEIFEQPDSVVNTMRGRV G +VLGGIK+Y+P+IKRCRRL+++ CGT
Sbjct: 330 MKGNYDYFMQKEIFEQPDSVVNTMRGRVRFDGNAIVLGGIKDYIPEIKRCRRLMLIGCGT 389
Query: 420 SYHSAIACRQIXXXXXXXXXXXXXASDFLDRETPIFRDDVCLFISQSGETADTLLALRYC 479
SYHSA+A RQ+ ASDFLDR TPIFRDDVC FISQSGETADTL+ALRYC
Sbjct: 390 SYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVCFFISQSGETADTLMALRYC 449
Query: 480 KPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLSDDR 539
K RGAL +G+TNTVGSSICRESHCG+HINAGPEIGVASTKAYTSQ +SL+MFAL +S+DR
Sbjct: 450 KQRGALIVGITNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQFISLVMFALVMSEDR 509
Query: 540 ISMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATCLEGA 599
+S+ +RR EI+ AL+ L + IR+VLQLD KV ++AK +Y+ KSLLIMGRG NFATCLEGA
Sbjct: 510 LSLQQRRLEILQALSKLADQIRDVLQLDSKVKELAKDLYQHKSLLIMGRGYNFATCLEGA 569
Query: 600 LKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARKGAP 659
LK+KEL+YMH EGIM+GELKHGPLA+VD+ + + M+V D VY K +NALQQV +RKG P
Sbjct: 570 LKVKELTYMHSEGIMAGELKHGPLALVDDSMPVLMIVLRDPVYVKCMNALQQVTSRKGCP 629
Query: 660 IIIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLA 719
III + E +H L +P+TVDC+Q ILTVIP+QLLSYHIA L G +VD PRNLA
Sbjct: 630 IIICEEGDEETKAFSSRH-LEIPRTVDCLQGILTVIPMQLLSYHIAVLRGCDVDCPRNLA 688
Query: 720 KSVTVE 725
KSVTVE
Sbjct: 689 KSVTVE 694
>emb|CAB46365.1| (Y18628) glucosamine--fructose-6-phosphate aminotransferase
[Drosophila melanogaster]
Length = 694
Score = 839 bits (2145), Expect = 0.0
Identities = 426/726 (58%), Positives = 535/726 (73%), Gaps = 33/726 (4%)
Query: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK 60
MCGIFAYLN+LTPK R E++D+LV GL+R+EYRGYDS G+AID + + ++ ++++
Sbjct: 1 MCGIFAYLNYLTPKSRQEVLDLLVTGLKRLEYRGYDSTGVAIDSPD-----NKNIVMVKR 55
Query: 61 AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV 120
GKV VL + I+E S + H GIAHTRWATHG P + NSHPHRS+D+N F+VV
Sbjct: 56 TGKVKVLEEAIQEHFSGREYSEPVLTHVGIAHTRWATHGVPCEKNSHPHRSDDENGFVVV 115
Query: 121 HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLEG 180
HNGIITNY ++K +L K+G++FES+TDTEV AKL H+ +P +SFR+LVE I Q+EG
Sbjct: 116 HNGIITNYNDVKTFLSKRGYEFESDTDTEVFAKLVHHLWKTHPTYSFRELVEQAILQVEG 175
Query: 181 AFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQTDGR 240
AFA+A KS FPG+ VASRR SPLLVGIK+ +RL T+H P+ + KD D+K +
Sbjct: 176 AFAIAVKSKYFPGECVASRRSSPLLVGIKTKTRLATDHIPILYGKD------DKKLCTDQ 229
Query: 241 RFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWEVEY 300
S +R E P + S+ST+ P + EVEY
Sbjct: 230 DADSGKPQDIRPHGQSRELP-----------------VLPRSESTSEFMPLEEK--EVEY 270
Query: 301 FVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEMELQEI 360
F ASDA+A+IEHT +V++LEDDDVA V DG L+IHR+ + D+ RE+ L+ME+Q+I
Sbjct: 271 FFASDASAVIEHTNRVIYLEDDDVAAVRDGTLSIHRLKKSLDD-PHAREITTLKMEIQQI 329
Query: 361 MKGSFKTYMQKEIFEQPDSVVNTMRGRVLPSGQ-VVLGGIKEYLPDIKRCRRLIMVACGT 419
MKG++ +MQKEIFEQPDSVVNTMRGRV G +VLGGIK+Y+P+IKRCRRL+++ CGT
Sbjct: 330 MKGNYDYFMQKEIFEQPDSVVNTMRGRVRFDGNAIVLGGIKDYIPEIKRCRRLMLIGCGT 389
Query: 420 SYHSAIACRQIXXXXXXXXXXXXXASDFLDRETPIFRDDVCLFISQSGETADTLLALRYC 479
SYHSA+A RQ+ ASDFLDR TPIFRDDVC FISQSGETADTL+ALRYC
Sbjct: 390 SYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVCFFISQSGETADTLMALRYC 449
Query: 480 KPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLSDDR 539
K RGAL +G+TNTVGSSICRESHCG+HINAGPEIGVASTKAYTSQ +SL+MFAL +S+DR
Sbjct: 450 KQRGALIVGITNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQFISLVMFALVMSEDR 509
Query: 540 ISMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATCLEGA 599
+S+ +RR EI+ AL+ L + IR+VLQLD KV ++AK +Y+ KSLLIMGRG NFATCLEGA
Sbjct: 510 LSLQQRRLEILQALSKLADQIRDVLQLDSKVKELAKDLYQHKSLLIMGRGYNFATCLEGA 569
Query: 600 LKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARKGAP 659
LK+KEL+YMH EGIM+GELKHGPLA+VD+ + + M+V D VY K +NALQQV +RKG P
Sbjct: 570 LKVKELTYMHSEGIMAGELKHGPLALVDDSMPVLMIVLRDPVYVKWMNALQQVTSRKGCP 629
Query: 660 IIIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLA 719
III + E +H L +P+TVDC+Q ILTVIP+QLLSYHIA L G +VD PRNLA
Sbjct: 630 IIICEEGDEETKAFSSRH-LEIPRTVDCLQGILTVIPMQLLSYHIAVLRGCDVDCPRNLA 688
Query: 720 KSVTVE 725
KSVTVE
Sbjct: 689 KSVTVE 694
>gb|AAF56785.1| (AE003765) CG1345 gene product [Drosophila melanogaster]
Length = 683
Score = 830 bits (2122), Expect = 0.0
Identities = 426/730 (58%), Positives = 537/730 (73%), Gaps = 52/730 (7%)
Query: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK 60
MCGIFAYLN+LTPK R E++D+L+QGL+R+EYRGYDS GIAID N E+ S+ L+++
Sbjct: 1 MCGIFAYLNYLTPKSRQEVLDLLLQGLKRLEYRGYDSTGIAIDALNSGEA--QSIMLVKR 58
Query: 61 AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV 120
GKV VL D + E D + + H GIAHTRWATHG P +VNSHP RS++ N F+VV
Sbjct: 59 TGKVKVLEDAVAEVCRGQDYSLPIDTHIGIAHTRWATHGVPSEVNSHPQRSDEDNSFVVV 118
Query: 121 HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLEG 180
HNGIITNY+++K LEK+G+ FES+TDTEVIAKL H+ ++P ++F +LVE IQQLEG
Sbjct: 119 HNGIITNYKDVKTLLEKRGYVFESDTDTEVIAKLVHHLWQQHPGYTFGELVEQAIQQLEG 178
Query: 181 AFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQTDGR 240
AFA+AFKS FPG+ VASRRGSPLLVGIK+ ++L T+H P+ ++K
Sbjct: 179 AFAIAFKSKHFPGECVASRRGSPLLVGIKAKTKLATDHIPILYAKA-------------- 224
Query: 241 RFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWEVEY 300
H H + + + + D +P + EVEY
Sbjct: 225 -----HRPHGQPQQQAYQL-------------------LPPGDCNAEFQPLERK--EVEY 258
Query: 301 FVASDAAAIIEHTKQVLFLEDDDVAFVE-DGALTIHRISRHADNGEQKREVKLLEMELQE 359
F ASDA+A+IEHT +V++LEDDDVA V+ DG L+IHR+++ +D+ RE+ L+ME+Q+
Sbjct: 259 FFASDASAVIEHTNRVIYLEDDDVAAVKSDGTLSIHRLNKSSDD-PHAREIITLKMEIQQ 317
Query: 360 IMKGSFKTYMQKEIFEQPDSVVNTMRGRVLPSGQ-VVLGGIKEYLPDIKRCRRLIMVACG 418
IMKG++ +M KEIFEQP+SVVNTMRGR+ Q VVLGGIKEY+P+IKRCRRL+++ACG
Sbjct: 318 IMKGNYDYFMLKEIFEQPESVVNTMRGRMRFDTQTVVLGGIKEYIPEIKRCRRLMLIACG 377
Query: 419 TSYHSAIACRQIXXXXXXXXXXXXXASDFLDRETPIFRDDVCLFISQSGETADTLLALRY 478
TSYHSA+A RQ+ ASDFLDR TPIFRDDVC FISQSGETADTL+ALRY
Sbjct: 378 TSYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVCFFISQSGETADTLMALRY 437
Query: 479 CKPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLSDD 538
CK RGAL +GVTNTVGSSICRESHCG+HINAGPEIGVASTKAYTSQ +SL+MFAL +S+D
Sbjct: 438 CKQRGALIVGVTNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQFISLVMFALVMSED 497
Query: 539 RISMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATCLEG 598
R+S+ +RR EIID L+ L E IR VL+L+ +V +AK++Y+ KSLLIMGRG NFATCLEG
Sbjct: 498 RLSLQQRRLEIIDGLSQLDEHIRTVLKLNSQVQQLAKELYEHKSLLIMGRGFNFATCLEG 557
Query: 599 ALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARKGA 658
ALK+KEL+YMH EGI++GELKHGPLA+VD+ + + M+V D VY K +NALQQV +RKG
Sbjct: 558 ALKVKELTYMHSEGILAGELKHGPLALVDKEMPVLMIVLRDPVYTKCMNALQQVTSRKGR 617
Query: 659 PIIIADCTVPEGDLAGMK---HILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRP 715
PI+I + EGD M L++P+TVDC+Q +LTVIPLQLLSYHIA L G +VD P
Sbjct: 618 PILICE----EGDNETMSFSTRSLQIPRTVDCLQGVLTVIPLQLLSYHIAVLRGCDVDCP 673
Query: 716 RNLAKSVTVE 725
RNLAKSVTVE
Sbjct: 674 RNLAKSVTVE 683
>ref|NP_038556.1| glutamine fructose-6-phosphate transaminase 1
sp|P47856|GFA1_MOUSE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1
(HEXOSEPHOSPHATE AMINOTRANSFERASE 1)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE 1) (GFAT 1)
(GFAT1)
pir||I53743 glutamine:fructose-6-phosphate amidotransferase - mouse
gb|AAC27348.1| (U00932) glutamine:fructose-6-phosphate amidotransferase [Mus
musculus]
Length = 681
Score = 803 bits (2051), Expect = 0.0
Identities = 406/730 (55%), Positives = 530/730 (71%), Gaps = 54/730 (7%)
Query: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEI--ESPHSSVALL 58
MCGIFAYLN+ P+ R EI++ L++GLQR+EYRGYDSAG+ +DG N+ E+ + L+
Sbjct: 1 MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGLDGGNDKDWEANACKIQLI 60
Query: 59 RKAGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFL 118
+K GKV L + + + D+D+D+E+++H GIAHTRWATHG P VNSHP RS+ NEF+
Sbjct: 61 KKKGKVKALDEEVHKQQ-DMDLDIEFDVHLGIAHTRWATHGEPNPVNSHPQRSDKNNEFI 119
Query: 119 VVHNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYP--DFSFRQLVETVIQ 176
V+HNGIITNY+++K++LE KG+ FESETDTE IAKL ++++D + D SF LVE VIQ
Sbjct: 120 VIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNWESQDVSFTTLVERVIQ 179
Query: 177 QLEGAFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQ 236
QLEGAFAL FKS FPGQ V +RRGSPLL+G++S +L T+H P+ + + G +K+
Sbjct: 180 QLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILY------RTGKDKK 233
Query: 237 TDGRRFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDW 296
GS + DSTT + P +
Sbjct: 234 --------------------------------------GSCGLSRVDSTTCLFPVEEK-- 253
Query: 297 EVEYFVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEME 356
VEY+ ASDA+A+IEHT +V+FLEDDDVA V DG L+IHRI R A + R V+ L+ME
Sbjct: 254 AVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTAGD-HPGRAVQTLQME 312
Query: 357 LQEIMKGSFKTYMQKEIFEQPDSVVNTMRGRV-LPSGQVVLGGIKEYLPDIKRCRRLIMV 415
LQ+IMKG+F ++MQKEIFEQP+SVVNTMRGRV V LGG+K+++ +I+RCRRLI++
Sbjct: 313 LQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILI 372
Query: 416 ACGTSYHSAIACRQIXXXXXXXXXXXXXASDFLDRETPIFRDDVCLFISQSGETADTLLA 475
ACGTSYH+ +A RQ+ ASDFLDR TP+FRDDVC FISQSGETADTL+
Sbjct: 373 ACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMG 432
Query: 476 LRYCKPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTL 535
LRYCK RGALT+G+TNTVGSSI RE+ CG+HINAGPEIGVASTKAYTSQ +SL+MFAL +
Sbjct: 433 LRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMM 492
Query: 536 SDDRISMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATC 595
DDRISM +RR+EI+ L LP+LI+EVL +D+++ +A ++Y +KS+LIMGRG ++ATC
Sbjct: 493 CDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATC 552
Query: 596 LEGALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVAR 655
LEGALKIKE++YMH EGI++GELKHGPLA+VD+ + + M++ D Y K NALQQVVAR
Sbjct: 553 LEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVAR 612
Query: 656 KGAPIIIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRP 715
+G P++I D E + K ++VP +VDC+Q IL+VIPLQLL++H+A L G +VD P
Sbjct: 613 QGRPVVICDKEDTE-TIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFP 671
Query: 716 RNLAKSVTVE 725
RNLAKSVTVE
Sbjct: 672 RNLAKSVTVE 681
>ref|NP_002047.1| glucosamine-fructose-6-phosphate aminotransferase;
glutamine-fructose-6-phosphate transaminase 1
sp|Q06210|GFA1_HUMAN GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1
(HEXOSEPHOSPHATE AMINOTRANSFERASE 1)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE 1) (GFAT 1)
(GFAT1)
pir||A45055 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) - human
gb|AAA58502.1| (M90516) glutamine:fructose-6-phosphate amidotransferase [Homo
sapiens]
Length = 681
Score = 799 bits (2040), Expect = 0.0
Identities = 405/730 (55%), Positives = 527/730 (71%), Gaps = 54/730 (7%)
Query: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEI--ESPHSSVALL 58
MCGIFAYLN+ P+ R EI++ L++GLQR+EYRGYDSAG+ DG N+ E+ L+
Sbjct: 1 MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKTQLI 60
Query: 59 RKAGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFL 118
+K GKV L + + + D+D+D+E+++H GIAHTRWATHG P VNSHP RS+ NEF+
Sbjct: 61 KKKGKVKALDEEVHKQQ-DMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFI 119
Query: 119 VVHNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYP--DFSFRQLVETVIQ 176
V+HNGIITNY+++K++LE KG+ FESETDTE IAKL ++++D D SF LVE VIQ
Sbjct: 120 VIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQ 179
Query: 177 QLEGAFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQ 236
QLEGAFAL FKS FPGQ V +RRGSPLL+G++S +L T+H P+ + + G +K+
Sbjct: 180 QLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILY------RTGKDKK 233
Query: 237 TDGRRFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDW 296
GS + DSTT + P +
Sbjct: 234 --------------------------------------GSCNLSRVDSTTCLFPVEEK-- 253
Query: 297 EVEYFVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEME 356
VEY+ ASDA+A+IEHT +V+FLEDDDVA V DG L+IHRI R A + R V+ L+ME
Sbjct: 254 AVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTAGD-HPGRAVQTLQME 312
Query: 357 LQEIMKGSFKTYMQKEIFEQPDSVVNTMRGRV-LPSGQVVLGGIKEYLPDIKRCRRLIMV 415
LQ+IMKG+F ++MQKEIFEQP+SVVNTMRGRV V LGG+K+++ +I+RCRRLI++
Sbjct: 313 LQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILI 372
Query: 416 ACGTSYHSAIACRQIXXXXXXXXXXXXXASDFLDRETPIFRDDVCLFISQSGETADTLLA 475
ACGTSYH+ +A RQ+ ASDFLDR TP+FRDDVC F+SQSGETADTL+
Sbjct: 373 ACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFLSQSGETADTLMG 432
Query: 476 LRYCKPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTL 535
LRYCK RGALT+G+TNTVGSSI RE+ CG+HINAGPEIGVASTKAYTSQ +SL+MFAL +
Sbjct: 433 LRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMM 492
Query: 536 SDDRISMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATC 595
DDRISM +RR+EI+ L LP+LI+EVL +D+++ +A ++Y +KS+LIMGRG ++ATC
Sbjct: 493 CDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATC 552
Query: 596 LEGALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVAR 655
LEGALKIKE++YMH EGI++GELKHGPLA+VD+ + + M++ D Y K NALQQVVAR
Sbjct: 553 LEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVAR 612
Query: 656 KGAPIIIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRP 715
+G P++I D E + K ++VP +VDC+Q IL+VIPLQLL++H+A L G +VD P
Sbjct: 613 QGRPVVICDKEDTE-TIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFP 671
Query: 716 RNLAKSVTVE 725
RNLAKSVTVE
Sbjct: 672 RNLAKSVTVE 681
>ref|NP_038557.1| glutamine fructose-6-phosphate transaminase 2
sp|Q9Z2Z9|GFA2_MOUSE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2
(HEXOSEPHOSPHATE AMINOTRANSFERASE 2)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE 2) (GFAT 2)
(GFAT2)
dbj|BAA74729.1| (AB016780) Glutamine:fructose-6-phosphate amidotransferase 2 [Mus
musculus]
Length = 682
Score = 795 bits (2030), Expect = 0.0
Identities = 410/729 (56%), Positives = 524/729 (71%), Gaps = 51/729 (6%)
Query: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSN-EIESPHSSVALLR 59
MCGIFAY+N+ PK R EI + L++GLQR+EYRGYDSAG+AIDG+N E++ H + L++
Sbjct: 1 MCGIFAYMNYRVPKTRKEIFETLIRGLQRLEYRGYDSAGVAIDGNNHEVKERH--IHLVK 58
Query: 60 KAGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLV 119
K GKV L + + + S +D+ +E+ H GIAHTRWATHG P VNSHP RS+ NEF+V
Sbjct: 59 KRGKVKALDEELYKQDS-MDLKVEFETHFGIAHTRWATHGVPNAVNSHPQRSDKDNEFVV 117
Query: 120 VHNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYP--DFSFRQLVETVIQQ 177
+HNGIITNY++++++LE KG++FESETDTE IAKL +++ D D +F LVE VIQQ
Sbjct: 118 IHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQ 177
Query: 178 LEGAFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQT 237
LEGAFAL FKS +PG+ VA+RRGSPLL+G++S +L T PV +
Sbjct: 178 LEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYP------------- 224
Query: 238 DGRRFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWE 297
T +E NI +M+ DS+T + D
Sbjct: 225 ----------------TCNIENVKNIC-----------KTRMKRLDSSTCLHAVG--DKA 255
Query: 298 VEYFVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEMEL 357
VE+F ASDA+AIIEHT +V+FLEDDD+A V DG L+IHR+ R A + + R ++ L+MEL
Sbjct: 256 VEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSATD-DPSRAIQTLQMEL 314
Query: 358 QEIMKGSFKTYMQKEIFEQPDSVVNTMRGRV-LPSGQVVLGGIKEYLPDIKRCRRLIMVA 416
Q+IMKG+F +MQKEIFEQP+SV NTMRGRV + V+LGG+K++L +I+RCRRLI++
Sbjct: 315 QQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIG 374
Query: 417 CGTSYHSAIACRQIXXXXXXXXXXXXXASDFLDRETPIFRDDVCLFISQSGETADTLLAL 476
CGTSYH+A+A RQ+ ASDFLDR TP+FRDDVC FISQSGETADTLLAL
Sbjct: 375 CGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLAL 434
Query: 477 RYCKPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLS 536
RYCK RGALT+G+TNTVGSSI RE+ CG+HINAGPEIGVASTKAYTSQ +SL+MF L +S
Sbjct: 435 RYCKDRGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMS 494
Query: 537 DDRISMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATCL 596
+DRIS+ RR+EII L LPELI+EVL LDEK+ D+A ++Y ++SLL+MGRG N+ATCL
Sbjct: 495 EDRISLQNRRQEIIRGLRSLPELIKEVLSLDEKIHDLALELYTQRSLLVMGRGYNYATCL 554
Query: 597 EGALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARK 656
EGALKIKE++YMH EGI++GELKHGPLA+VD+ + + MV+ D + K NALQQV AR+
Sbjct: 555 EGALKIKEITYMHSEGILAGELKHGPLALVDKQMPVIMVIMKDPCFAKCQNALQQVTARQ 614
Query: 657 GAPIIIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRPR 716
G PII+ E K I +P TVDC+Q IL+VIPLQLLS+H+A L G +VD PR
Sbjct: 615 GRPIILCSKDDTESSKFAYKTI-ELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPR 673
Query: 717 NLAKSVTVE 725
NLAKSVTVE
Sbjct: 674 NLAKSVTVE 682
>ref|NP_005101.1| glutamine-fructose-6-phosphate transaminase 2
sp|O94808|GFA2_HUMAN GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2
(HEXOSEPHOSPHATE AMINOTRANSFERASE 2)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE 2) (GFAT 2)
(GFAT2)
dbj|BAA74731.1| (AB016789) Glutamine:fructose-6-phosphate amidotransferase [Homo
sapiens]
Length = 682
Score = 790 bits (2017), Expect = 0.0
Identities = 406/729 (55%), Positives = 523/729 (71%), Gaps = 51/729 (6%)
Query: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSN-EIESPHSSVALLR 59
MCGIFAY+N+ P+ R EI + L++GLQR+EYRGYDSAG+AIDG+N E++ H + L++
Sbjct: 1 MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNHEVKERH--IQLVK 58
Query: 60 KAGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLV 119
K GKV L + + + S +D+ +E+ H GIAHTRWATHG P VNSHP RS+ NEF+V
Sbjct: 59 KRGKVKALDEELYKQDS-MDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVV 117
Query: 120 VHNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYP--DFSFRQLVETVIQQ 177
+HNGIITNY++++++LE KG++FESETDTE IAKL +++ D D +F LVE VIQQ
Sbjct: 118 IHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQ 177
Query: 178 LEGAFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQT 237
LEGAFAL FKS +PG+ VA+RRGSPLL+G++S +L T P+ +
Sbjct: 178 LEGAFALVFKSVHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPILY-------------- 223
Query: 238 DGRRFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWE 297
T +E NI +M+ DS+ + D
Sbjct: 224 ---------------RTCTLENVKNIC-----------KTRMKRLDSSACLHAVG--DKA 255
Query: 298 VEYFVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEMEL 357
VE+F ASDA+AIIEHT +V+FLEDDD+A V DG L+IHR+ R A + + R ++ L+MEL
Sbjct: 256 VEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSASD-DPSRAIQTLQMEL 314
Query: 358 QEIMKGSFKTYMQKEIFEQPDSVVNTMRGRV-LPSGQVVLGGIKEYLPDIKRCRRLIMVA 416
Q+IMKG+F +MQKEIFEQP+SV NTMRGRV + V+LGG+K++L +I+RCRRLI++
Sbjct: 315 QQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIG 374
Query: 417 CGTSYHSAIACRQIXXXXXXXXXXXXXASDFLDRETPIFRDDVCLFISQSGETADTLLAL 476
CGTSYH+A+A RQ+ ASDFLDR TP+FRDDVC FISQSGETADTLLAL
Sbjct: 375 CGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLAL 434
Query: 477 RYCKPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLS 536
RYCK RGALT+GVTNTVGSSI RE+ CG+HINAGPEIGVASTKAYTSQ +SL+MF L +S
Sbjct: 435 RYCKDRGALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMS 494
Query: 537 DDRISMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATCL 596
+DRIS+ RR+EII L LPELI+EVL L+EK+ D+A ++Y ++SLL+MGRG N+ATCL
Sbjct: 495 EDRISLQNRRQEIIRGLRSLPELIKEVLSLEEKIHDLALELYTQRSLLVMGRGYNYATCL 554
Query: 597 EGALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARK 656
EGALKIKE++YMH EGI++GELKHGPLA++D+ + + MV+ D + K NALQQV AR+
Sbjct: 555 EGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFAKCQNALQQVTARQ 614
Query: 657 GAPIIIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRPR 716
G PII+ E K I +P TVDC+Q IL+VIPLQLLS+H+A L G +VD PR
Sbjct: 615 GRPIILCSKDDTESSKFAYKTI-ELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPR 673
Query: 717 NLAKSVTVE 725
NLAKSVTVE
Sbjct: 674 NLAKSVTVE 682
>sp|P53704|GFA1_CANAL GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
pir||JC6012 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) - yeast (Candida albicans)
emb|CAA64380.1| (X94753) glucosamine--fructose-6-phosphate aminotransferase
(isomerizing) [Candida albicans]
Length = 713
Score = 701 bits (1789), Expect = 0.0
Identities = 376/746 (50%), Positives = 498/746 (66%), Gaps = 54/746 (7%)
Query: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDG------SNEIESPHSS 54
MCGIF Y+NFL K R EI+D L++GLQR+EYRGYDSAGIA+DG SN E S
Sbjct: 1 MCGIFGYVNFLVDKSRGEIIDNLIEGLQRLEYRGYDSAGIAVDGKLTKDPSNGDEEYMDS 60
Query: 55 VALLRKAGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDK 114
+ +++ GKV VL I + +D ++ H GIAHTRWATHG P+ N HPH+S+ K
Sbjct: 61 I-IVKTTGKVKVLKQKIIDDQ--IDRSAIFDNHVGIAHTRWATHGQPKTENCHPHKSDPK 117
Query: 115 NEFLVVHNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDR------YPDFSFR 168
EF+VVHNGIITNY +++YL KGH FESETDTE IAKL +H +D +PD +
Sbjct: 118 GEFIVVHNGIITNYAALRKYLLSKGHVFESETDTECIAKLFKHFYDLNVKAGVFPDLN-- 175
Query: 169 QLVETVIQQLEGAFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAG 228
+L + V+ +LEG++ L KS +PG++ +R+GSPLLVG+K++ +L+ + V F
Sbjct: 176 ELTKQVLHELEGSYGLLVKSYHYPGEVCGTRKGSPLLVGVKTDKKLKVDFVDVEFEAQ-- 233
Query: 229 WKWGDEKQTDGRRFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAV 288
+ + + N AT E F+ + G + S S
Sbjct: 234 ----QQHRPQQPQINHNGATSAA-ELGFIPV-------------APGEQNLRTSQS---- 271
Query: 289 RPFDSDD---WEVEYFVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGE 345
R F S+D VE+F++SD A++++HTK+VLFLEDDD+A + DG L IHR S +
Sbjct: 272 RAFLSEDDLPMPVEFFLSSDPASVVQHTKKVLFLEDDDIAHIYDGELRIHRASTKSAGES 331
Query: 346 QKREVKLLEMELQEIMKGSFKTYMQKEIFEQPDSVVNTMRGRV-LPSGQVVLGGIKEYLP 404
R ++ LEMEL EIMKG +K +MQKEIFEQPDS NTMRGR+ + V LGG+K +L
Sbjct: 332 TVRPIQTLEMELNEIMKGPYKHFMQKEIFEQPDSAFNTMRGRIDFENCVVTLGGLKSWLS 391
Query: 405 DIKRCRRLIMVACGTSYHSAIACRQIXXXXXXXXXXXXXASDFLDRETPIFRDDVCLFIS 464
I+RCRR+IM+ACGTSYHS +A R I ASDFLDR +P+FRDD C+F+S
Sbjct: 392 TIRRCRRIIMIACGTSYHSCLATRSIFEELTEIPVSVELASDFLDRRSPVFRDDTCVFVS 451
Query: 465 QSGETADTLLALRYCKPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQ 524
QSGETAD++LAL+YC RGALT+G+ N+VGSS+ R++HCG+HINAGPEIGVASTKAYTSQ
Sbjct: 452 QSGETADSILALQYCLERGALTVGIVNSVGSSMSRQTHCGVHINAGPEIGVASTKAYTSQ 511
Query: 525 ILSLLMFALTLSDDRISMAKRREEIIDALNDLPELIREVLQLDEKVLDIA-KQIYKEKSL 583
++L+MFAL+LS+D IS R EEII L +PE I++VL+L+ K+ D+ + +KSL
Sbjct: 512 YIALVMFALSLSNDSISRKGRHEEIIKGLQKIPEQIKQVLKLENKIKDLCNSSLNDQKSL 571
Query: 584 LIMGRGLNFATCLEGALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYK 643
L++GRG FAT LEGALKIKE+SYMH EG+++GELKHG LA+VDE L I D ++
Sbjct: 572 LLLGRGYQFATALEGALKIKEISYMHSEGVLAGELKHGILALVDEDLPIIAFATRDSLFP 631
Query: 644 KSLNALQQVVARKGAPIIIADCTVPEGDLA----GMKHILRVPKTVDCVQNILTVIPLQL 699
K ++A++QV AR G PI+I + EGD + L VP+TVDC+Q +L VIPLQL
Sbjct: 632 KVMSAIEQVTARDGRPIVICN----EGDAIISNDKVHTTLEVPETVDCLQGLLNVIPLQL 687
Query: 700 LSYHIAELNGANVDRPRNLAKSVTVE 725
+SY +A G +VD PRNLAKSVTVE
Sbjct: 688 ISYWLAVNRGIDVDFPRNLAKSVTVE 713
Database: nr
Posted date: Jul 9, 2000 11:06 PM
Number of letters in database: 162,524,432
Number of sequences in database: 517,904
Lambda K H
0.320 0.136 0.391
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 214034356
Number of Sequences: 517904
Number of extensions: 8714863
Number of successful extensions: 21905
Number of sequences better than 10.0: 198
Number of HSP's better than 10.0 without gapping: 130
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 21259
Number of HSP's gapped (non-prelim): 270
length of query: 725
length of database: 162,524,432
effective HSP length: 59
effective length of query: 666
effective length of database: 131,968,096
effective search space: 87890751936
effective search space used: 87890751936
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 74 (33.2 bits)
