Score E
Sequences producing significant alignments: (bits) Value
pir||T32987 hypothetical protein C05D2.5 - Caenorhabditis e... 1457 0.0
gb|AAF56697.1| (AE003760) Hmu gene product [Drosophila mela... 40 0.071
gb|AAF59265.1| (AE003841) CG11112 gene product [Drosophila ... 39 0.12
gb|AAC47118.1| (U42014) hemomucin [Drosophila melanogaster] 39 0.16
ref|NP_010289.1| high copy suppressor of cAMP-dependent pro... 38 0.27
pir||T29710 hypothetical protein C14E2.3 - Caenorhabditis e... 38 0.36
pir||T00037 hypothetical protein KIAA0284 - human (fragment) 38 0.36
dbj|BAA22953.2| (AB006622) KIAA0284 protein [Homo sapiens] 38 0.36
pir||F72285 transcription regulator, crp family - Thermotog... 38 0.36
gb|AAF60950.1| (AC006833) Hypothetical protein ZK616.j [Cae... 38 0.47
gb|AAF57473.1| (AE003792) CG8929 gene product [alt 1] [Dros... 38 0.47
gb|AAF58880.1| (AE003831) CG1472 gene product [Drosophila m... 38 0.47
gb|AAF32417.1| (AF069392) chemotaxis protein CheA [Vibrio p... 37 0.61
ref|NP_014213.1| predicted to encode a ubiquitin-processing... 37 0.80
dbj|BAA31635.1| (AB014560) KIAA0660 protein [Homo sapiens] 37 0.80
pir||PQ0479 pistil extensin-like protein (clone pMG14) - co... 37 0.80
pir||C41710 promastigote surface antigen-2 (clone 2.5) - Le... 37 0.80
gb|AAD55440.1|AF181655_1 (AF181655) BcDNA.LD27873 [Drosophi... 36 1.1
emb|CAB40750.1| (AL031884) /prediction=(method:""genscan"",... 36 1.1
pir||T16450 hypothetical protein F53B3.2 - Caenorhabditis e... 36 1.4
gb|AAA84401.1| (U31961) ORF1; similar to human alpha-actini... 36 1.4
gb|AAC67205.1| (AC005171) putative retroelement pol polypro... 36 1.4
gb|AAB61104.1| (AC002062) EST gb|T21469 comes from this gen... 36 1.4
gb|AAF55366.1| (AE003715) CG8953 gene product [Drosophila m... 36 1.4
pir||S27786 acidic protein - Caenorhabditis elegans (fragme... 36 1.8
sp|P34256|YKA4_CAEEL HYPOTHETICAL 82.8 KD PROTEIN B0303.4 I... 36 1.8
sp|P47321|Y075_MYCGE HYPOTHETICAL PROTEIN MG075 >gi|1361615... 36 1.8
gb|AAF60743.1| (AC006797) contains similarity to Pfam famil... 36 1.8
pir||T28155 erythrocyte membrane protein 1 - Plasmodium fal... 35 2.4
dbj|BAA20768.1| (AB002307) KIAA0309 [Homo sapiens] 35 2.4
ref|NP_006653.1| Snf2-related CBP activator protein >gi|510... 35 2.4
dbj|BAA94838.1| (AB041926) GCK family kinase MINK-2 [Homo s... 35 2.4
ref|NP_002366.1| microtubule-associated protein 4 >gi|64191... 35 2.4
ref|NP_056531.1| Misshapen/NIK-related kinase >gi|6970478|d... 35 2.4
sp|P27816|MAP4_HUMAN MICROTUBULE-ASSOCIATED PROTEIN 4 >gi|1... 35 2.4
pir||A53253 microtubule-associated protein 4 - human (fragm... 35 2.4
pir||I53035 trithorax homolog HTX - human (fragment) >gi|10... 35 3.1
pir||I38485 BCR11q23 - human (fragment) >gi|451555|gb|AAA18... 35 3.1
gb|AAD29829.1|AC006202_7 (AC006202) putative proline/hydrox... 35 3.1
dbj|BAA97287.1| (AB018120) retroelement pol polyprotein-lik... 35 3.1
gb|AAD28550.1|AF111943_1 (AF111943) development protein DG1... 35 3.1
ref|NP_005924.1| myeloid/lymphoid or mixed-lineage leukemia... 35 3.1
sp|O18400|PIX1_DROME PITUITARY HOMEOBOX 1 HOMOLOG (D-PTX1) ... 35 3.1
pir||I52578 ALL-1 protein - human (fragment) 35 3.1
gb|AAD51933.1|AF145285_1 (AF145285) RNA-binding protein iso... 35 3.1
sp|Q03164|HRX_HUMAN ZINC FINGER PROTEIN HRX (ALL-1) (TRITHO... 35 3.1
gb|AAC37520.1| (L22179) MLL-AF4 der(11) fusion protein [Hom... 35 3.1
gb|AAF39401.1| (AE002324) conserved hypothetical protein [C... 35 3.1
pir||A44265 trithorax homolog HTX, version 2 - human 35 3.1
pir||A44264 trithorax homolog HTX, version 1 - human (fragm... 35 3.1
Alignments
>pir||T32987 hypothetical protein C05D2.5 - Caenorhabditis elegans
gb|AAC02722.1| (AF047651) C05D2.5 gene product [Caenorhabditis elegans]
Length = 774
Score = 1457 bits (3731), Expect = 0.0
Identities = 731/774 (94%), Positives = 731/774 (94%)
Query: 1 MRSGQDSKKKTERTGRKTSIDXXXXXXXXXDETSRPSMVSLRLSKLNKYNLTRIQLQSED 60
MRSGQDSKKKTERTGRKTSID DETSRPSMVSLRLSKLNKYNLTRIQLQSED
Sbjct: 1 MRSGQDSKKKTERTGRKTSIDRRAWPRRRRDETSRPSMVSLRLSKLNKYNLTRIQLQSED 60
Query: 61 FQKRKWLCDLKMMSSEPIVANLDNSMTTEPAPAAFPPISPMSFAFMNEEERAAVKFPKVD 120
FQKRKWLCDLKMMSSEPIVANLDNSMTTEPAPAAFPPISPMSFAFMNEEERAAVKFPKVD
Sbjct: 61 FQKRKWLCDLKMMSSEPIVANLDNSMTTEPAPAAFPPISPMSFAFMNEEERAAVKFPKVD 120
Query: 121 PKPQTAKDDEPSTSQKXXXXXXXXXXXXXXXXXXPPASSSNYEPKAHIGWASFGDSCLPP 180
PKPQTAKDDEPSTSQK PPASSSNYEPKAHIGWASFGDSCLPP
Sbjct: 121 PKPQTAKDDEPSTSQKTLSVDDLLIVDDDDETDSPPASSSNYEPKAHIGWASFGDSCLPP 180
Query: 181 PPKPVKKATDPNLPRRKVYVIRSQNTDKSKSPLVVNNQQVTLEKAQNSPKNPNPVVSKPI 240
PPKPVKKATDPNLPRRKVYVIRSQNTDKSKSPLVVNNQQVTLEKAQNSPKNPNPVVSKPI
Sbjct: 181 PPKPVKKATDPNLPRRKVYVIRSQNTDKSKSPLVVNNQQVTLEKAQNSPKNPNPVVSKPI 240
Query: 241 VLTXXXXXXXXXXXXXXXXAIKIMADPTRPPDLPPQRSLISRFESNRTKRDIFRNSYDSD 300
VLT AIKIMADPTRPPDLPPQRSLISRFESNRTKRDIFRNSYDSD
Sbjct: 241 VLTDSDEDVDVVGFDEEEEAIKIMADPTRPPDLPPQRSLISRFESNRTKRDIFRNSYDSD 300
Query: 301 EEEFLRSRYQRAVTPPPILERQSGSTRESVSEPSEGKILEEDATLGSEHTERVGKRIELE 360
EEEFLRSRYQRAVTPPPILERQSGSTRESVSEPSEGKILEEDATLGSEHTERVGKRIELE
Sbjct: 301 EEEFLRSRYQRAVTPPPILERQSGSTRESVSEPSEGKILEEDATLGSEHTERVGKRIELE 360
Query: 361 EINPSQLLRTKISASAIPILPLSKSIMERKKVALEMTKNAVIRQANNFRPKAKNSTVAPK 420
EINPSQLLRTKISASAIPILPLSKSIMERKKVALEMTKNAVIRQANNFRPKAKNSTVAPK
Sbjct: 361 EINPSQLLRTKISASAIPILPLSKSIMERKKVALEMTKNAVIRQANNFRPKAKNSTVAPK 420
Query: 421 SVQIPAYNHKTPMTFYSNMAAPAFVKGVNGRCYRCAEIQKPVDMSSFRFVDDSTVIAIRA 480
SVQIPAYNHKTPMTFYSNMAAPAFVKGVNGRCYRCAEIQKPVDMSSFRFVDDSTVIAIRA
Sbjct: 421 SVQIPAYNHKTPMTFYSNMAAPAFVKGVNGRCYRCAEIQKPVDMSSFRFVDDSTVIAIRA 480
Query: 481 HLCDQTRVMVARTAIWNREYAKRLGDRAAGTVWQKPDEVSAQMTGFCSATVRRCIEIANM 540
HLCDQTRVMVARTAIWNREYAKRLGDRAAGTVWQKPDEVSAQMTGFCSATVRRCIEIANM
Sbjct: 481 HLCDQTRVMVARTAIWNREYAKRLGDRAAGTVWQKPDEVSAQMTGFCSATVRRCIEIANM 540
Query: 541 SIIPKCADRVGVSRNELTSLKSSFGSEKFCGQTMRAPHVLTQFYSVNQASMARNREGSDG 600
SIIPKCADRVGVSRNELTSLKSSFGSEKFCGQTMRAPHVLTQFYSVNQASMARNREGSDG
Sbjct: 541 SIIPKCADRVGVSRNELTSLKSSFGSEKFCGQTMRAPHVLTQFYSVNQASMARNREGSDG 600
Query: 601 PSSSAARPVGRPPTTQPVETAVEKKKNDEDEKRHHPLTNFTTASTSSQNLQDQPPPKNTV 660
PSSSAARPVGRPPTTQPVETAVEKKKNDEDEKRHHPLTNFTTASTSSQNLQDQPPPKNTV
Sbjct: 601 PSSSAARPVGRPPTTQPVETAVEKKKNDEDEKRHHPLTNFTTASTSSQNLQDQPPPKNTV 660
Query: 661 LRWSNITTPRILRPPTLKTPYSLPRTAVIPVMKKKQPEIEQVQPKKDTTASLVRKRGRPR 720
LRWSNITTPRILRPPTLKTPYSLPRTAVIPVMKKKQPEIEQVQPKKDTTASLVRKRGRPR
Sbjct: 661 LRWSNITTPRILRPPTLKTPYSLPRTAVIPVMKKKQPEIEQVQPKKDTTASLVRKRGRPR 720
Query: 721 KEKPLEVQSPRKGLYLRFKSCTKYIVRTPIDKSVQETVNYLLDEVDKRASTSAT 774
KEKPLEVQSPRKGLYLRFKSCTKYIVRTPIDKSVQETVNYLLDEVDKRASTSAT
Sbjct: 721 KEKPLEVQSPRKGLYLRFKSCTKYIVRTPIDKSVQETVNYLLDEVDKRASTSAT 774
>gb|AAF56697.1| (AE003760) Hmu gene product [Drosophila melanogaster]
Length = 579
Score = 40.2 bits (92), Expect = 0.071
Identities = 33/135 (24%), Positives = 49/135 (35%), Gaps = 9/135 (6%)
Query: 601 PSSSAARPVGRPPTTQPVETAVEKKKNDEDEKRHHPLTNFTTASTSSQNLQDQPPPKNTV 660
PS + +P P TT P T + P T TT +T+ + K T
Sbjct: 436 PSKATPKPKAAPSTTTPKPTTTTTTTTPK------PTTKTTTTTTTPKPTTTTTTKKPTT 489
Query: 661 LRWSNITTPR--ILRPPTLKTPYSLPRTAVIPVMKKKQPEIEQVQPKKDTTASLVRKRGR 718
+ TTP+ +PPT K + T P +P K V ++
Sbjct: 490 TTTTTTTTPKPTTTKPPTAKPSTTTTTTTTPKPTTTTTPTTPTPEPSKPKVKRTVPEKPA 549
Query: 719 PRKEK-PLEVQSPRK 732
P +E P + Q P+K
Sbjct: 550 PVEEDIPSDTQPPKK 564
Score = 35.6 bits (80), Expect = 1.8
Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 14/126 (11%)
Query: 601 PSSSAARPVGRPPTTQPVETAVEKKKNDEDEKRHHPLTNFTTASTSSQNLQDQPPPKNTV 660
P+++ +P T T K K+ P T TT +T+ + +PP
Sbjct: 454 PTTTTTTTTPKPTTKTTTTTTTPKPTTTTTTKK--PTTTTTTTTTTPKPTTTKPPTAKPS 511
Query: 661 LRWSNITTPRILRPPTLKTPYSLPRTAVIPVMKKKQPE----IEQ-----VQPKKDTTAS 711
+ TTP +P T TP + P +K+ PE +E+ QP K
Sbjct: 512 TTTTTTTTP---KPTTTTTPTTPTPEPSKPKVKRTVPEKPAPVEEDIPSDTQPPKKEKLK 568
Query: 712 LVRKRG 717
++ K+G
Sbjct: 569 VINKQG 574
>gb|AAF59265.1| (AE003841) CG11112 gene product [Drosophila melanogaster]
Length = 159
Score = 39.5 bits (90), Expect = 0.12
Identities = 36/140 (25%), Positives = 58/140 (40%), Gaps = 19/140 (13%)
Query: 603 SSAARPVGRPPTTQPVETAVEKKKNDEDEKRH--HPLTNFTTASTSSQNLQDQPPPKNTV 660
SSA P P +P + +K EDEKR + L + T + + N
Sbjct: 13 SSAPEPEPEPSHAKPNTYSNKKANTKEDEKRQFLNTLVKLCKSETEKGFVNPKQTISNIN 72
Query: 661 LRWSNITTPRILRPPTLKTPYSLPRTAVIPVMKKKQPEIEQVQPKKDTTASLVRKRGRPR 720
+NI+ P I PP + V+ K + E+ + Q K A ++++R +
Sbjct: 73 TITNNISMPEIQLPP------------ITVVIVKDEKELAKYQEKSKNGAIIIKRRSNAK 120
Query: 721 KE-KPLEVQSPRKGLYLRFK 739
++ KP +PR GL R K
Sbjct: 121 EDTKP----APRTGLQERTK 136
>gb|AAC47118.1| (U42014) hemomucin [Drosophila melanogaster]
Length = 582
Score = 39.1 bits (89), Expect = 0.16
Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 18/132 (13%)
Query: 601 PSSSAARPVGRPPTTQPVETAVEKKKNDEDEKRHHPLTNFTTASTSSQNLQDQPPPKNTV 660
P+++ +P T T K K+ P T TT +T+ + +PP
Sbjct: 454 PTTTTTTTTPKPTTKTTTTTTTPKPTTTTTTKK--PTTTTTTTTTTPKPTTTKPP----T 507
Query: 661 LRWSNITTPRILRPPTLKTPYSLPRTAVIPVMKKKQPEIEQVQPKKDTTASLVRKRGRPR 720
+ S TTP PT T P T P + +P++++ P+K
Sbjct: 508 AKPSTTTTPTTTPKPTTTT---TPTTPTTPTPEPSKPKVKRTVPEKPAPV---------E 555
Query: 721 KEKPLEVQSPRK 732
+E P + Q P+K
Sbjct: 556 EEIPSDTQPPKK 567
>ref|NP_010289.1| high copy suppressor of cAMP-dependent protein kinase A
temperature-sensitive mutations; Sok1p
sp|P40317|SOK1_YEAST SOK1 PROTEIN
pir||S50987 SOK1 protein - yeast (Saccharomyces cerevisiae)
emb|CAA88066.1| (Z48008) Sok1p [Saccharomyces cerevisiae]
Length = 901
Score = 38.3 bits (87), Expect = 0.27
Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 20/135 (14%)
Query: 575 RAPHVLTQFYSVNQASMARNRE--GSDGPSSSAARPVGRPPT---TQPVETAVEKKKNDE 629
R+ V+T S+N ++ A N + G+ SS P+ R T T +T K +D
Sbjct: 106 RSSGVITPSMSLNASTNATNNDSSGNSANSSDLKIPIDRDNTIFKTFDTKTGQFLKNDDN 165
Query: 630 DEKRHHPLTNFTTASTSSQNLQDQPPPKNTVLRWSNITTPRILRPPTLKTPYSLPRTAVI 689
+E+ N D PPKN ++NI P PP+ K P S +
Sbjct: 166 EEEIRR------------NNKVDSIPPKNI---YTNINNPSPSPPPSSKQPPSASAPQLP 210
Query: 690 PVMKKKQPEIEQVQP 704
P + + + Q QP
Sbjct: 211 PATEPHKEQAAQQQP 225
>pir||T29710 hypothetical protein C14E2.3 - Caenorhabditis elegans
gb|AAA85748.1| (U46671) weak similarity to S. cerevisiae verprolin (SP:P37370)
[Caenorhabditis elegans]
Length = 205
Score = 37.9 bits (86), Expect = 0.36
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 11/116 (9%)
Query: 181 PPKPVKKATDPNLPRRKVY------VIRSQNTDKSKSPLVVNNQQVTLEKAQNSP---KN 231
PP P+K+A+ PNLP+ +++ VI Q S P + + + NS +
Sbjct: 53 PPPPIKEASCPNLPQIRIHDPLVFSVISEQTEQASTFPTDIPAAETAPSQKLNSECGIEK 112
Query: 232 PNPVVSKPIVLTXXXXXXXXXXXXXXXXAI--KIMADPTRPPDLPPQRSLISRFES 285
P V+ P+ + ++ + PT PP P L++R +S
Sbjct: 113 KQPTVTAPVTIDSSSTAEQEPPQKTQSTSVLPNVSPFPTPPPVPPKPTHLMARMDS 168
>pir||T00037 hypothetical protein KIAA0284 - human (fragment)
Length = 1323
Score = 37.9 bits (86), Expect = 0.36
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 9/91 (9%)
Query: 556 ELTSLKSSFGSEKFCGQTMRAPH-VLTQFYSVNQASMARNREGSDGPSSSAARPVGR--- 611
E L +S +E G T R P L+ V+ AS R G GPS + +P+
Sbjct: 869 EARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKE 928
Query: 612 ----PPTTQ-PVETAVEKKKNDEDEKRHHPL 637
PP Q P TA+ + E++HHPL
Sbjct: 929 MSPSPPAAQDPGGTALVSAREQSSERQHHPL 959
>dbj|BAA22953.2| (AB006622) KIAA0284 protein [Homo sapiens]
Length = 1498
Score = 37.9 bits (86), Expect = 0.36
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 9/91 (9%)
Query: 556 ELTSLKSSFGSEKFCGQTMRAPH-VLTQFYSVNQASMARNREGSDGPSSSAARPVGR--- 611
E L +S +E G T R P L+ V+ AS R G GPS + +P+
Sbjct: 869 EARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKE 928
Query: 612 ----PPTTQ-PVETAVEKKKNDEDEKRHHPL 637
PP Q P TA+ + E++HHPL
Sbjct: 929 MSPSPPAAQDPGGTALVSAREQSSERQHHPL 959
>pir||F72285 transcription regulator, crp family - Thermotoga maritima (strain
MSB8)
gb|AAD36246.1|AE001774_3 (AE001774) transcriptional regulator, crp family [Thermotoga
maritima]
Length = 201
Score = 37.9 bits (86), Expect = 0.36
Identities = 19/71 (26%), Positives = 36/71 (49%)
Query: 322 QSGSTRESVSEPSEGKILEEDATLGSEHTERVGKRIELEEINPSQLLRTKISASAIPILP 381
+ G + +P E ++ + TL +EH GK +E++EI P Q++ + S+ P P
Sbjct: 16 RKGEIVKHQDDPIEDVLILLEGTLKTEHVSENGKTLEIDEIKPVQIIASGFIFSSEPRFP 75
Query: 382 LSKSIMERKKV 392
++ E K+
Sbjct: 76 VNVVAGENSKI 86
>gb|AAF60950.1| (AC006833) Hypothetical protein ZK616.j [Caenorhabditis elegans]
Length = 491
Score = 37.5 bits (85), Expect = 0.47
Identities = 31/111 (27%), Positives = 48/111 (42%), Gaps = 21/111 (18%)
Query: 641 TTASTSSQNLQDQPPPKNTVLRWSNITTPRILRPPTLKTPYSLPRTAVIPVMKKKQPE-- 698
TT+ ++SQ +D PPPKN TP P KTP +P + K+PE
Sbjct: 353 TTSDSNSQVSEDIPPPKN-----KESGTP----PLKEKTPEPIPEEPKKVEEEVKKPEVP 403
Query: 699 ----------IEQVQPKKDTTASLVRKRGRPRKEKPLEVQSPRKGLYLRFK 739
+++ PK + V+ P+ E PLEV+ +K + + K
Sbjct: 404 KNEEPKMEEPVKEEAPKVEEKKEEVKMVEDPKVESPLEVKKMKKRIQINVK 454
Database: nr
Posted date: Jul 9, 2000 11:06 PM
Number of letters in database: 162,524,432
Number of sequences in database: 517,904
Lambda K H
0.313 0.128 0.364
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 237566437
Number of Sequences: 517904
Number of extensions: 9957570
Number of successful extensions: 27779
Number of sequences better than 10.0: 102
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 106
Number of HSP's that attempted gapping in prelim test: 27545
Number of HSP's gapped (non-prelim): 323
length of query: 774
length of database: 162,524,432
effective HSP length: 63
effective length of query: 711
effective length of database: 129,896,480
effective search space: 92356397280
effective search space used: 92356397280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (21.9 bits)
S2: 74 (33.2 bits)
