Macrophages '94

Feb. 10 and 11, 1994 Juzen Auditorium, Kanazawa

Univ Sch of Medicine, Kanazawa, Conference

Chairman: Kouji Matsushima (Kanazawa Univ)

 

Signal Processing Mechanism

1.   Role of proteasemes in antigen processing, Keiji

Tanaka (Tokushima Univ)

2.   In vivo activation of Langerhans cells, Setsuya

  Aiba (Tohoku Univ)

3.   The role of the MAP kinase cascade in signal transduction pathways, Eisuke Nishida (Kyoto

  Univ)

4.   Intracellular molecular events regulating IL-8 gene expression, Naofumi Mukaida, Shu-ichi Okamoto, Yuji Ishikawa, Kouji Matsushima

  (Kanazawa Univ)

5.   Ceramide as a second messenger in TNF and IL-1 receptor signalling, Stefan Schutz, Katja Wiegmann, Thomas Machleidt, Martin Kronke

  (Technical Univ. Munich)

6.   Activated platelets induce superoxide anion release by monocytes and neutrophils through P-selectin (CD62), Tsutomu Tsuji, Kisaburo Nagata, Junzo Koike, Tatsuro Irimura (Tokyo Univ)

Pathophysiology of Nitric Oxide

1. The high output nitric oxide pathway: Biological

  role and regulation, Qiao-wen Xie,

   Carl Nathan (Cornell Univ)

 2. Role of NO in endotoxin shock and intervention

   by NO antagonists, imidazolineozxyl N-oxide

   derivatives, Hiroshi Maeda (Kumamoto Univ)

 3. NO and carcinogenesis, Hiroyasu Esumi

   (National Cancer Center Research Center)

In vivo Roles of Cytokines

1.   A novel host defense cytokine: Interleukin-13, A. Minty, P.Liauzun, N.Vita, A.Doyle, L. Montaner, S.Gordon, D.Caput, P.Ferrara (Sanofi Elf Bio Recherches and Oxford Univ)

2.   Pathophysiological roles of IL-8 in acute inflammation, A.Harada, N.Sekido, N.Mukaida, K.Matsushima (Kanazawa Univ)

3.   Establishiment of the role of IL-6 and TNFa using gene knock-out mice, H.Bluthmann, A. Althage, G.Kohler, M.Kopf, W.Lesslauer, J.Rothe (F. Hoffmann-La Roche, Univ Zurich,

  Max-Planck-Insitute)

4.   Functional analysis of IL-6 signal transducer,

gp130 and NF-IL6 by gene targetting, Nobuaki

Yoshida (Osaka Medical Center Maternal and

Child Health)