
E-mail: 116301-at-ib.k.u-tokyo.ac.jp
(メールを送る際は、"-at-"を@に変えて下さい。)
出身大学: 東京理科大学 薬学部
The Department of Medicinal and Life Science,
Faculty of Pharmaceutical Sciences,
Tokyo University of Science
学士研究題名:
Glucose類似体を用いたhSGLT1の輸送特性の検討
修士研究題名:海馬新生ニューロンの前シナプス終末特異的な神経伝達阻害モデルマウスを用いた
記憶研究
博士研究題名:
成体海馬新生ニューロンの前シナプス終末特異的な神経伝達阻害の神経新生と
記憶への影響
興味分野・対象:
I am interested in brain function, particularly in memory function. In the memory function, I would like to know the role of adult generated neurons in the hippocampus.
● The role of adult generated neurons in memory function:
Adult neurogenesis in the hippocampus is involved in many kinds of memory function such as pattern separation. How do newborn neurons affect memory process or any kinds of memory function?
● Connection:
Cell assembly, functional network, interaction between neurons and other cells (for example, interneurons, mossy cells, astrocytes, and microglias in the hippocampus)
● Memory dynamics:
the time-dependent change of region, networks, or cells preserving memory information post learning
I have also interest in neurological disorders with cognitive dysfunction such as Alzheimer’s disease.
研究手技:
Behavioral experiments, Retrovirus labeling, Immunohistochemistry
研究業績:
○Asai H, Abe Y, McHugh TJ, Hisatsune T,
"The effect of attenuated neurotransmitter release in hippocampal adult born neurons on hippocampal neurogenesis, microstructure and function" The 38th Annual Meeting of the Japan Neuroscience society, Poster No. 2P024, Kobe, July 2015
○Asai H, McHugh TJ, Hisatsune T
"The effect of attenuating neurotransmitter release in hippocampal newborn neurons on memory tasks"
The 44th Annual Meeting of the Society for Neuroscience, Poster No. SS49 359.07, Washington, DC America, Nov. 2014
○Asai H, McHugh TJ, Hisatsune T
"The impact of transgenic blockade of neurotransmitter release in newborn neurons on hippocampal dependent memory"
The 37th Annual Meeting of the Japan Neuroscience society, Poster No. P3-093, Yokohama, Sept. 2014
○Asai H, McHugh TJ, Abe Y, Kaneko J, Imayoshi I, Kageyama R, Hisatsune T
"Affected memory function in transgenic mice with the attenuated presynaptic neurotransmission of hippocampal adult-born neurons"
The 36th Annual Meeting of the Japan Neuroscience society, Poster No. P2-1-99, Kyoto, June 2013
コメント:
I would like to research overseas someday.