眞鍋 昇 (MANABE Noboru, Ph. D.)
Professor, Research Unit for Animal Life Sciences
Animal Resource Science Center, The University of Tokyo（3145 Ago, Ibaraki-Iwama 319-0206, Japan. Tel: +(81)-299-45-8952 (direc to Noboru MANABE), Fax: +(81)-299-45-5950, e-mail: amanabe@mail.ecc.u-tokyo.ac.jp)
【関連学会】 日本獣医学会 日本畜産学会 日本繁殖生物学会 日本農芸化学会 日本獣医解剖学会
学 術 創 成 研 究 Pacific Conference on Reproductive Biology and Environmental Sciences
動物生命科学シンポジウム 動物生命フィールド科学（サマースクール）
研究内容 研究業績 (New) 研究業績 (Old) 海外渡航歴 研究助成
生年月日：1954（昭和29）年07月02日生（午ウマ歳・蟹座）
履 歴
・ 氏名：眞鍋 昇（まなべ のぼる）
・
・所属先：東京大学 大学院農学生命科学研究科
高等動物教育研究センター・附属牧場
実験資源動物科学研究室・ 職：教授
・
・所属先住所：〒319-0206 茨城県西茨城郡岩間町安居3145
Tel: 0299-45-8952（直）/ 0299-45-2606（代）, Fax: 0299-45-5950
E-mail: amanabe@mail.ecc.u-tokyo.ac.jp・ 略歴：
生年月日：1954（昭和29）年７月２日（満50歳）
本籍地：香川県（香川県三豊郡詫間町大字詫間2168-1番地）
最終学歴：京都大学 大学院農学研究科 博士後期過程 終了
学位：京都大学 農学博士（大学院農学研究科1986年課程博士）
「脊椎動物における骨格筋線維の比較組織化学的研究」・賞罰など：1990年9月30日・欧州細胞病理学会奨励賞
「In situ PCR法による肝炎ウイルスの超高感度検出法に関する研究」
1998年3月30日・日本畜産学会学会賞
「骨格筋生理学的特性の定量組織化学および構造生物学的解析に関する研究」・ 教育歴・職歴など：
1973年３月 香川県立丸亀高等学校卒業
1978年３月 京都大学 農学部 卒業
1983年３月 京都大学大学院 農学研究科博士後期過程終了
「骨格筋生理学的特性の定量組織化学および構造生物学的解析に関する研究」
1983年４月 日本農薬株式会社 医薬・安全性研究所・研究員
「農薬の安全性評価・医薬品の探索」
1988年９月 パストゥール研究所分子細胞病理学研究部門・研究員
「C型肝炎ウイルス患者における自然治癒の分子機構」
1992年４月 京都大学 農学部・助教授
「外因性内分泌攪乱物質の哺乳類生殖系における安全性評価」
「卵胞の選択的死滅制御機構とその人為支配による潜在的卵巣卵の利用」
2004年7月 東京大学大学院 農学生命科学研究科・教授
「同上」・所属学会など：日本繁殖生物学会・理事
日本獣医学会、日本獣医解剖学会・評議員
日本畜産学会、関西畜産学会・評議員
日本薬学会、日本農芸化学会・代議員
日本解剖学会、日本組織細胞化学会、老化促進モデル動物研究会・評議員・学術雑誌等の役割
Journal of Reproduction and Development（編集副委員長）
Reproductive Biology and Endocrinology（編集委員）
Asian Ausralian Journal of Animal Science （編集委員）
FEBS letters（審査員）
Biochemica et Biophysica Acta（審査員）
European Journal of Cellular Pathology（審査員）
Life Science Journal（審査員）
Endocrine Journal（審査員）
Molecular Reproduction and Development（審査員）・ 学外委員等の役割
平成13～19年度：文部科学省科学技術政策研究所 科学技術動向研究所
科学技術専門家ネットワーク・専門調査員
平成13～16年度：日本学術振興会特別研究員等審査会等専門委員
科学研究費委員会専門委員
平成17～21年度：農林水産省交付金プロジェクト研究評価委員
特許の取得：組織の冷却保存液（宮本元, 杉本実紀, 眞鍋昇）
特許公開番号2001-277401・平成13年 9月11日
出願番号：2000-57143・平成12（2000）年3月2日
国際交流（海外渡航歴など）
1993年 H.5.7.24～5.8.9 欧州分子細胞病理学会・学術講演・
フランス（パリ）
国際生理科学会・学術講演・連合王国（グラスゴー）
1994年 H.6.11.11～6.11.19 米国肝臓病学会・学術講演・アメリカ合衆国
（シカゴ）国際研究集会派遣研究員旅費
1995年 H.7.6.10～7.6.26 欧州分子細胞病理学会・学術講演・フランス
（ストラスブール）
欧州細胞生理学会総会・招待講演・イタリア
（ローマ）
1996年 H.8.11.11～8.11.17 米国肝臓病学会・学術講演・アメリカ合衆国
（シカゴ）国際研究集会派遣研究員旅費
1997年 H.9.11.4～9.11.14 米国肝臓病学会・学術講演・アメリカ合衆国
（シカゴ）国際研究集会派遣研究員旅費
H.9.11.4-5 カルフォルニア工科大学（CALTEC）・共同研究
アメリカ合衆国（パサデナ）
H.9.12.5～9.12.15 欧州細胞病理学会シンポジウム・招待講演・
フランス（ボルドー）
1998年 H.10.12.11～10.12.23 欧州細胞病理学会シンポジウム出席・招待講演
フランス（パリ）
1999年 H.11.9.16～11.9.27 世界獣医学大会・学術講演・フランス（リヨン）
国際研究集会派遣研究員旅費
2000年 H.12.11.26～12.12.10 国際組織細胞化学会大会・招待講演・英国
（ロンドン）
2001年 H.13.1.4～13.1.17 欧州細胞病理学会シンポジウム・招待講演・
フランス（パリ）
H.13.10.25～13.10.28 環太平洋生殖生物環境科学コンファレンス・共催
韓国（清州・チョンジュ）特定領域研究A2
H.13.12.21～13.12.31 欧州細胞病理学会シンポジウム・招待講演・
フランス（グルノーブル）
2002年 H.14.6.26～14.7.11 第16回国際組織細胞学会・学術講演・連合王国
（エジンバラ）
第85回欧州家畜繁殖学会・招待講演・ハンガリー
（ブダペスト）
H.14.8.24～14.9.2 フランス共和国国立科学研究センター（CNRS）・
特別招聘講演・フランス（パリ）
H.14.9.22～14.9.28 第５回アジア太平洋州生理学会・内分泌攪乱物質
シンポジウム・招待講演・マレーシア
（クアラルンプール）
2003年 H.15.7.15～15.7.21 第36回米国生殖生物学会・学術講演・アメリカ
合衆国（シンシナティー）
2004年 H.16.4.10～16.4.15 第1回アジア太平洋生殖生物工学会・招待講演
ベトナム（ホーチミン）
H.16.6.17～16.6.24 第６回アジア太平洋生理学会・招待講演・
マレーシア（クアラルンプール）
H.16.7.17～16.8.10 第12回国際組織細胞化学会・学術講演・
アメリカ合衆国（ラホヤ）
第37回米国生殖生物学会・学術講演・カナダ
（バンクーバー）
H.16.11.10～16.11.15 海南省農業科学技術院・華南農業大学校・
招待講演および共同研究・中国（海口市・広州市）
H.16.11.17～16.12.4 第13回欧州創傷治癒学会・学術講演・スイス
（ニヨン）
第19回欧州分子細胞病理生理学会・招待講演・
フランス（パリ）
第18回国際組織化学細胞化学会・招待講演・
連合王国（ロンドン）
2005年 H.17.1.4～17.1.10 延辺大学農学院・招待講演および共同研究・中国
（延吉市）
H.17.2.1～17.2.10 カセサート大学獣医学部・招待講演および共同研
究・タイ（バンコック市）
第７回アジア太平洋生理学会・招待講演・
マレーシア（クアラルンプール）
H.17.3.9～17.3.16 第109回ユーロコンファレンス・パスツール研
究所・招待講演・フランス（パリ）
ボルドー第２大学医学部・招待講演および共同研
究・フランス（ボルドー）
H.17.5.5～17.5.8 環太平洋生殖生物環境科学コンファレンス・共催・
韓国（清州）
研究費の獲得など
文部科学省・日本学術振興会科学研究補助金
�氈F本人が代表の研究課題一般研究(C)
平成５、６年度（1993、1994年）
研究代表者：京都大学農学部・助教授・眞鍋 昇
研究課題：組織切片に含まれる細胞間マトリックスとそのmRNAの精密な定量法の開発
課題番号：05660344一般研究(C)
平成７、８年度（1995、1996年）
研究代表者：京都大学農学部・助教授・眞鍋 昇
研究課題：卵胞退行における顆粒層細胞のアポトーシスの役割とその制御機構
課題番号：07660379試験研究(B)(1)
平成７、８、９年度（1995、1996、1997年）
研究代表者：京都大学農学部・助教授・眞鍋 昇
研究課題：リサイクル・廃棄資源の飼料化による小型肉用草食家畜の活用体系の確立
課題番号：07556129基盤研究(B)(2)(一般)
平成９、10、11年度（1997、1998、1999年）
研究代表者：京都大学農学研究科・助教授・眞鍋 昇
研究課題：卵胞の選択死：顆粒層細胞にアポトーシスを誘導する新規細胞死受容体の同定と分子制御
課題番号：09460127萌芽研究
平成９、10年度（1997、1998年）
研究代表者：京都大学農学研究科・助教授・眞鍋 昇
研究課題：卵胞顆粒層細胞にのみ特異的にアポトーシスを誘導する新規な細胞死受容体の探索
課題番号：09876080基盤研究(B)(1)
平成11、12、13年度（1999、2000、2001年）
研究代表者：京都大学農学研究科・助教授・眞鍋 昇
研究課題：家畜生殖遺伝毒性評価システムの構築：構造生物学・細胞生物学的評価法の確立
課題番号：11556052萌芽研究
平成11、12年度（1999、2000年）
研究代表者：京都大学農学研究科・助教授・眞鍋 昇
研究課題：卵胞の選択的死滅を決定する新規顆粒層細胞特異的アポトーシス受容体の探索とその制御
課題番号：11876064基盤研究(B)(2)
平成12、13、14年度（2000、2001、2002年）
研究代表者：京都大学農学研究科・助教授・眞鍋 昇
研究課題：選択的卵胞閉鎖の分子制御機構の解明とその人為支配
課題番号：12460125特定領域研究(A)(2)
平成13年度（2001年）
研究代表者：京都大学農学研究科・助教授・眞鍋 昇
研究課題：内分泌攪乱物質による生殖毒性評価システムの構築：構造生物学・細胞生物学的リアルタイム評価法の確立
課題番号：13027241萌芽研究
平成13、14年度（2001、2002年）
研究代表者：京都大学農学研究科・助教授・眞鍋 昇
研究課題：卵胞の選択的死滅を決定する新規顆粒層細胞特異的アポトーシス受容体の探索とその制御
課題番号：13876066学術創成研究（2）
平成13、14、15、16，17年度（2001、2002、2003，2004，2005年）
研究代表者：京都大学農学研究科・助教授・眞鍋 昇
研究課題：哺乳類卵胞の選択的死滅制御機構とその人為支配による潜在的卵巣卵の利用（Regulation mechanism of follicular atresia in mammalian ovaries and artificial control for availableness of potential oocytes in the ovaries）
課題番号：13GS0008�：分担の課題
一般研究(B)
平成５、６、７年度（1993、1994、1995年）
研究代表者：京都大学農学部・教授・宮本 元
研究課題：家畜卵巣の灌流培養による卵細胞成熟の人為支配
課題番号：05454112試験研究(B)(1)
平成６、７、８年度（1994、1995、1996年）
研究代表者：京都大学農学部・教授・宮本 元
研究課題：核磁気共鳴装置による家畜生殖遺伝毒性の新評価法の開発
課題番号：06556048一般研究(B)
平成７、８年度（1995、1996年）
研究代表者：国立予防衛生研究所・ウイルス第二部・室長・松浦善治
研究課題：ペスティウイルス及びC型肝炎ウイルスの成熟複製機構に関する研究
課題番号：07456137基盤研究(B)(2)
平成７、８、９年度（1996、1997、1998年）
研究代表者：京都大学農学部・教授・宮本 元
研究課題：卵胞顆粒層細胞の選択死を誘導する受容体分子の検索
課題番号：08456141基盤研究(A)(1)(展開)
平成９、10、11、12年度（1997、1998、1999、2000年）
研究代表者：京都大学農学研究科・教授・宮本 元
研究課題：核磁気共鳴装置による家畜生殖遺伝毒性の構造生物学的評価法
課題番号：09356008基盤研究(B)(企画)
平成９、10、11年度（1997年）
研究代表者：京都大学農学研究科・教授・宮本 元
研究課題：生殖遺伝毒性の評価：環境汚染物質による生殖遺伝毒性の構造生物学的評価法の創出
課題番号：09596002萌芽研究
平成10、11年度（1998年）
研究代表者：京都大学農学研究科・教授・宮本 元
研究課題：耐凍蛋白遺伝子のex vivo導入による生殖器官の凍結保存
課題番号：10876058基盤研究(B)(2)
平成10、11、12年度（1998、1999、2000年）
研究代表者：東北大学加齢医学研究所・教授・福本 学
研究課題：肝移植が適応となる原発性肝癌の鑑別に多中心性肝癌の検討と移植後再発の予測を中心として
課題番号：10000000基盤研究(C)(1)
平成10年度（1998年）
研究代表者：横浜市立大学・理学部・教授・井口 泰泉
研究課題：日本の内分泌撹乱化学物質（環境ホルモン）研究のネットワーク作り
課題番号：10600001基盤研究(B)(2)
平成11、12、13年度（1999、2000、2001年）
研究代表者：京都大学農学研究科・教授・宮本 元
研究課題：生殖細胞の選択的死滅制御機構の解明とその人為的支配
課題番号：11460127基盤研究(B)(1)
平成12、13、14年度（2000、2001、2002年）
研究代表者：大阪大学医学部・助教授・黒澤 努
研究課題：ネフローゼ自然発症マウス系統の基盤を確立し、慢性腎不全の治療につなげる
課題番号：12480252萌芽研究
平成12、13年度（2000、2001年）
研究代表者：京都大学農学研究科・教授・宮本 元
研究課題：耐凍性タンパク質遺伝子等のex vivo導入による卵巣の凍結保存
課題番号：12876061特定領域研究(A)
平成14、15年度（2002、2003年）
研究代表者：京都大学農学研究科・教授・宮本 元
研究課題：内分泌攪乱物質による生殖毒性評価システムの構築：構造生物学・細胞生物学的リアルタイム評価法の確立
課題番号：13027241基盤研究(B)(2)
平成14、15年度（2002、2003年）
研究代表者：京都大学農学研究科・教授・宮本 元
研究課題：生体ＮＭＲイメージング法による生殖毒性のリアルタイム評価法の創出
課題番号：14360167萌芽研究
平成14、15年度（2002、2003年）
研究代表者：京都大学農学研究科・教授・宮本 元
研究課題：耐凍性タンパク等の遺伝子導入による卵巣凍結保存法の創出
課題番号：14656104基盤研究（Ｓ）
平成16～20年度（2004～2008年）
研究代表者：東北大学農学研究科・教授・佐藤英明
研究課題：卵子の細胞分化・死滅調節系の解明による次世代型動物発生工学技術の基盤形成
課題番号：16108003基盤研究(C)
平成17～19年度（2005～2007年）
研究代表者：京都大学農学研究科・助手・杉本実紀
研究課題：卵巣内に存在する生殖幹細胞の超低温保存法の開発
課題番号：17580254基盤研究(B)
平成17～19年度（2005～2007年）
研究代表者：東京大学農学生命科学研究科・助教授・中山裕之
研究課題：βアミロイド沈着と脳老化の比較生物学的研究
課題番号：17658129財団等からの研究補助金
住友財団環境研究助成金
平成５年度（1993～94年）
研究代表者：眞鍋 昇
研究課題：生体ＮＭＲによる環境毒物の肝毒性の高感度検出法の開発
助成番号：93-104-176稲盛財団研究助成金
平成７年度（1995年）
研究代表者：眞鍋 昇
研究課題：卵巣卵胞細胞のアポトーシスの分子細胞制御機構伊藤記念財団研究助成金
平成７年度（1995年）
研究代表者：眞鍋 昇
研究課題：卵胞顆粒層細胞のアポトーシスの役割と制御機構 (Roles and regulation mechanisms of apoptic cell death in follicular granulosa cells)
助成番号：７伊財第20号伊藤記念財団研究助成金
平成８年度（1996年）
研究代表者：眞鍋 昇
研究課題：顆粒層細胞におけるアポトーシス・シグナルの伝達制御機構（Transfer mechanisms of apoptotic signals in follicular granulosa cells）
助成番号：８伊財第20号伊藤記念財団研究助成金
平成９年度（1997年）
研究代表者：眞鍋 昇
研究課題：卵胞顆粒層細胞にアポトーシスを誘導する新規細胞死受容体（A novel receptor induces apoptotic cell death in follicular granulosa cells）
助成番号：９伊財第2１号伊藤記念財団研究助成金
平成10年度（1998年）
研究代表者：眞鍋 昇
研究課題：ブタ顆粒層細胞アポトーシスを阻止する新規阻害因子（Novel inhibiting factors of apoptosis in pig follicular granulosa cells）
助成番号：10伊財第19号武田財団研究助成金
平成11年度（1999年）
研究代表者：眞鍋 昇
研究課題：卵胞特異的に発現し卵胞選択を支配する新規細胞死受容体
助成番号：伊藤記念財団研究助成金
平成11年度（1999年）
研究代表者：眞鍋 昇
研究課題：ブタ卵胞顆粒層細胞の新規細胞死およびデコイ受容体の特性（Characteristics of a novel cell death- and a decoy-receptor on porcine follicular granulosa cells）
助成番号：11伊財第23号稲盛財団研究助成金
平成12年度（2000年）
研究代表者：眞鍋 昇
研究課題：ほ乳類卵胞の選択的死滅を制御する遺伝子の同定とその人為支配（Identification and manipulation of novel cell death receptor gene regulating selective follicular atresia in mammalian ovaries）伊藤記念財団研究助成金
平成13年度（2001年）
研究代表者：眞鍋 昇
研究課題：ブタ卵胞の選択的死滅機構の解明とその人為支配（Mechanism of porcine follicle selection and artificial control）
助成番号：13伊財第22号
PUBLICATIONS
(1998-2005)1) ARTICLES
2) REVIEWS
3) BOOKS
4) PROCEEDINGS
1) ARTICLES
1. Noboru Manabe. Histochemical and structure-biological quantification of muscle physiological properties. Animal Science and Technology, 69 (8): 815-833, 1998.
2. Yoshihiro Kimura, Noboru Manabe, Hiroko Matsushita, Chiemi Tajima, Akira Myomoto, Hajime Miyamoto. Examination of granulosa cell glycoconjugates which change during follicular atresia in the pig ovary. Journal of Reproduction and Development, 44 (1): 35-44, 1998.
3. Miki Sugimoto, Noboru Manabe, Yoshihiro Kimura, Akira Myomoto, Yuzuru Imai, Hiroko Ohno, Hajime Miyamoto. Ultrastructural changes in granulosa cells in porcine antral follicles undergoing atresia indicate apoptotic cell death. Journal of Reproduction and Development, 44 (1): 7-14, 1998.
4. Hajime Miyamoto, Miki Sugimoto, Tomohiko Okuda, Yohichi Takahagi, Noboru Manabe. Assessment of the effect of dimethyl sulfoxide on the survival of cryopreserved mouse morulae by single step exposure and rapid freezing. Theriogenology, 49 (1): 171, 1998.
5. Makoto Miyamoto, Noboru Manabe, Kozue Uchio, Keiko Kuramitsu, Kotaro Tamura, Yoshihiro Furuya, Nobuo Nagano, Hajime Miyamoto. Characteristics of lectin staining patterns assessed by a modified sensitive thermo-method in rat livers with heterologous serum-induced fibrosis. The Journal of Veterinary Medical Science, 60 (8): 953-960, 1998.
6. Mizuho Nakayama, Shotaro Nisimura, Kaoru Okano, Hisao Iwamoto, Hajime Miyamoto, Noboru Manabe. Immunohistochemical localization of basic fibroblast growth factor in the goat pituitary gland. Journal of Mammalian Ova Research, 16 (1): 53-58, 1999.
7. Yuzuru Imai, Noboru Manabe, Kozue Uchio, Akiko Kinoshita, Yoshihiro Kimura, Mizuho Nakayama, Susumu Nishihara, Satoko Wada, Miki Sugimoto, Hajime Miyamoto. Interactions of apoptosis and extracellular matrices in granulosa cells of atretic follicles in porcine ovaries. Journal of Mammalian Ova Research, 16 (1): 59-66, 1999.
8. Yoshihiro Kimura, Noboru Manabe, Susumu Nishihara, Hiroko Matsushita, Chiemi Tajima, Satoko Wada, Hajime Miyamoto. Up-regulation of the _2,6-sialyltransferase messenger ribonucleic acid increases glycoconjugates containing _2,6-linked sialic acid residues in granulosa cells during follicular atresia of porcine ovaries. Biology of Reproduction, 60 (10): 1475-1482, 1999.
9. Kozue Uchio, Noboru Manabe, Akiko Kinoshita, Kotaro Tamura, Makoto Miyamoto, Atsuo Ogura , Yoshie Yamamoto, Hajime Miyamoto. Abnormalities of extracellular matrices and transforming growth factor _1 localization in the kidney of the hereditary nephrotic mice (ICGN strain). The Journal of Veterinary Medical Science, 61 (7): 769-776, 1999.
10. Shuichi Yoshimura, Eiichi Hondo, Hiroshi Murabayashi, Nobuo Kitamura, Akio Miyamoto, Noboru Manabe, Yoshihisa Hasegawa, Junzo Yamada. Stage-specific distributions of inhibin a-subunit in bovine ovarian follicles and corresponding concentrations of various hormones in follicular fluid. Journal of Reproduction and Development, 45 (2): 213-222, 1999.
11. Miki Sugimoto, Noboru Manabe, Maki Morita, Hajime Miyamoto. Comparison of nuclear magnetic resonance microimages and histology of rat ovaries. Journal of Reproduction and Development, 46 (1): 57-63, 1999.
12. Noboru Manabe, Akira Myomoto, Chiemi Tajima, Manabu Fukumoto, Mizuho Nakayama, Kozue Uchio, Misuzu Yamaguchi, Hajime Miyamoto. Immunochemical characteristics of a novel cell death receptor and a decoy receptor on granulosa cells of porcine ovarian follicles. Cytotechnology, 33 (1): 189-201, 2000.
13. Noboru Manabe, Yasuyoshi Azuma, Miki Sugimoto, Kozue Uchio, Naoki Taketomo, Hiroshi Tsuchita, Hajime Miyamoto. Effects of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism and blood flow in dietary hypoferric anemic mice. British Journal of Nutrition, 83 (2): 197-204, 2000.
14. Miki Sugimoto, Shinnji Maeda, Noboru Manabe, Hajime Miyamoto. Development of infantile rat ovaries autotransplanted after cryopreservation by vitrification. Theriogenology, 53 (10): 1093-1103, 2000.
15. Kotaro Tamura, Noboru Manabe, Kozue Uchio, Makoto Miyamoto, Akiko Kinoshita, Atsuo Ogura, Yoshie Yamamoto, Nobuo Nagano, Yoshihiro Furuya, Hajime Miyamoto. Characteristic changes in carbohydrate profile in the kidneys of hereditary nephrotic mice (ICGN strain). The Journal of Veterinary Medical Science, 62 (3): 379-390, 2000.
16. Mizuho Nakayama, Noboru Manabe, Susumu Nishihara, Hajime Miyamoto. Species specific differences in apoptotic cell localization in granulosa and theca interna cells during follicular atresia in porcine and bovine ovaries. Journal of Reproduction and Development, 46 (1): 147-156. 2000.
17. Susumu Nishihara, Noboru Manabe, Mizuho Nakayama, Satoko Wada, Naoko Inoue, Hajime Miyamoto. Changes in cell adhesion molecules during follicular atresia in porcine ovaries. Journal of Reproduction and Development, 46 (3): 325-334. 2000.
18. Kozue Uchio, Noboru Manabe, Kotaro Tamura, Makoto Miyamoto, Misuzu Yamaguchi, Atsuo Ogura, Yoshie Yamamoto, Hajime Miyamoto. Decreased matrix metalloproteinase activity in the kidneys of hereditary nephrotic mice (ICGN strain). Nephron, 86 (2): 145-151, 2000.
19. Miki Sugimoto, Noboru Manabe, Maki Morita, Hajime Miyamoto. Comparison of nuclear magnetic resonance microimages and histology of rat ovaries. Journal of Reproduction and Devevelopment, 46 (1): 57-63, 2000.
20. Noboru Manabe, Yasuyoshi Azuma, Miki Sugimoto, Takako Tanaka, Namiko Kiso, Misuzu Yamaguchi, Kozue Uchio-Yamada, Hajime Miyamoto. A Novel in vivo 31P nuclear magnetic resonance technique for assessment of liver failure induced by chlorinated-hydrocarbon in mice. Biomedical Research, 21 (6): 317-326, 2000.
21. Tsuchita Hiroshi, Noboru Manabe, Saito Satoshi. Influence of food ingredients on iron availability. Biofactors, 12 (1): 59-64, 2000.
22. Noboru Manabe, Akiko Kinoshita, Misuzu Yamaguchi, Yoshihiro Furuya, Nobuo Nagano, Kozue Yamada-Uchio, Naotsugu Akashi, Keiko Miyamoto-Kuramitsu, Hajime Miyamoto. Changes in quantitative profile of extracellular matrix components in the kidneys of rats with adriamycin-induced nephropathy. The Journal of Veterinary Medical Science, 63 (2): 125-133. 2001.
23. Noboru Manabe, Masakazu Irie, Mitsuru Mitsumoto, Yoshihiro Furuya, Misuzu Yamaguchi, Hajime Miyamoto. Immunohistochemical quantification of fast-myosin in upper hind limb muscles of the pig. Animal Science Journal, 72 (2): 154-163, 2001.
24. Noboru Manabe, Akira Myomoto, Chiemi Tajima, Mizuho Nakayama, Misuzu Yamaguchi, Kozue Yamada-Uchio, Hajime Miyamoto. Monoclonal antibodies recognize a novel cell death receptor and a decoy receptor on granulosa cells of porcine ovarian follicles. Journal of Mammalian Ova Research, 18 (1): 20-32. 2001.
25. Mizuho Nakayama, Noboru Manabe, Kozue Yamada-Uchio, Hajime Miyamoto. Changes in localization of type I, III and IV collagens and their mRNA expression during follicular atresia in bovine and porcine ovaries. Journal of Reproduction and Development, 47 (1): 27-36, 2001.
26. Noboru Manabe, Miki Sugimoto, Yasuyoshi Azuma, Takako Tanaka, Kozue Uchio, Hajime Miyamoto. A novel in vivo NMR technique to assess halocarbon induced hepatic failure in mice. Water Science and Technology, 17 (1): 32-38, 2001.
27. Minako Kiso, Noboru Manabe, Kohji Komatsu, Noriyuki Nisioka, Nami Nakai-Sugimoto, Hajime Miyamoto. Abnormal accumulation of luteal bodies in ovaries of the senescence accelerated mouse (SAM). Journal of Reproduction and Devevelopment, 47 (3): 153-164, 2001.
28. Eiichi Hondo, Tohru Kobayashi, Tsunehiko Aita, Noboru Manabe, Nobuo Kitamura, Junzo Yamada, Yashuharu Namba, Yoshitaka Nagahama, Yasuo Kiso. Molecular cloning and expression of suppressor of potassium transport defect 3 (SKD3) in rat testis. Journal of Reproduction and Devevelopment, 47 (3): 173-180, 2001.
29. Misuzu Yamaguchi, Noboru Manabe, Kozue Uchio-Yamada, Naotsugu Akashi, Yoshie Yamamoto, Atsuo Ogura, Hajime Miyamoto. localization of proliferative and apoptotic cells in the kidneys of ICR-derived glomerulonephritis (ICGN) mice. The Journal of Veterinary Medical Science, 63 (7): 781-787, 2001.
30. Yoshinori Okamura, Akira Myomoto, Noboru Manabe, Nobuyuki Tanaka, Hitoshi Okamura, Manabu Fukumoto. Protein tyrosine kinase expression in the porcine ovary. Molecular Human Reproduction, 7 (8): 723-729, 2001.
31. Kozue Uchio-Yamada, Noboru Manabe, Misuzu Yamaguchi, Naotsugu Akashi, Yoshie Yamamoto, Atsuo Ogura, Hajime Miyamoto. Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome. The Journal of Veterinary Medical Science, 63 (11): 1171-1178, 2001.
32. Br_ssow K-P, Torner H, Kanitz W, Ratky J, Noboru Manabe, Solti L. Biotechnological aspects of embryo transfer in swine. Hungarian Journal of Animal Breeding and Nutrition, 50 (6): 481-493, 2001.
33. Uchio K, Tuchweber B, Noboru Manabe, Gabbiani G, Rosenbaum J, Desmouli_re A. Expression of cellular retinol-binding protein-1 during myofibroblastic differentiation in hepatic stellate cell and portal fibroblasts. Hepatology, 34: 40pp4-406, (2001).
34. Satoko Wada, Noboru Manabe, Naoko Inoue, Mizuho Nakayama, Toshikatsu Matsui, Hajime Miyamoto. TRAIL-decoy receptor-1 disappears in granulosa cells of atretic follicles in porcine ovaries. Journal of Reproduction and Devevelopment, 48 (2): 167-173, 2002.
35. Satoko Wada, Noboru Manabe, Naoko Inoue, Mizuho Nakayama, Toshikatsu Matsui, Hajime Miyamoto. TRADD is involved in apoptosis induction in granulosa cells during atresia in pig ovaries. Journal of Reproduction and Devevelopment, 48 (2): 175-181, 2002.
36. Hideki Tonomura, Takeshi Miyake, Yukio Taniguchi, Noboru Manabe, Hiroyuki Kose, Kozo Matsumoto, Takahisa Yamada, Yoshiyuki Sasaki. Detection of quantitative trait locus for rat model useful for genetic analysis of intramascular fat accumulation using the OLETF rat. The Journal of Veterinary Medical Science, 64 (1): 45-50, 2002.
37. Miki Sugimoto, Noboru Manabe, Maki Morita, Takako Tanaka, Reika Okamoto, Satoshi Imanishi, Hajime Miyamoto. NMR microscopic observation of mouse embryo malformations induced by maternal administration of retinoic acid. The Journal of Veterinary Medical Science, 64 (5): 427-433, 2002.
38. Satoko Wada, Noboru Manabe, Mizuho Nakayama, Naoko Inoue, Toshikatsu Matsui, Hajime Miyamoto. TRAIL-decoy receptor-1 plays inhibitory role in apoptosis of granulosa cells from pig ovarian follicules. The Journal of Veterinary Medical Science, 64 (5): 435-439, 2002.
39. Kozue Uchio, Beatriz Tuchweber, Noboru Manabe, Giulio Gabbiani, Jean Rosenbaum And Alexis Desmouliere. Cellular retinol-binding protein-1 expression and modulation during in vivo and in vitro myofibroblastic differentiation of rat hepatic stellate cells and portal fibroblasts. Laboratory Investigation, 82 (5): 619-628, 2002.
40. Chiemi Tajima, Noboru Manabe, Mizuho Nakayama, Naoko Inoue, Toshikatsu Matsui, Eiichi Hondo, Hajime Miyamoto Hajime. Monoclonal antibody recognizes follicular granulosa cell antigens in porcine ovaries. Journal of Reproduction and Devevelopment, 48: 567-572, 2002.
41. Satoshi Imanishi, Noboru Manabe, Takako Tanaka, Reika Okamoto, Maki Morita, Miki Sugimoto, Hajime Miyamoto. mRNA of GPCR5B/Raig2, a novel orphan receptor, expresses in murine placentae. Journal of Reproduction and Devevelopment, 48: 627-632, 2002.
42. Mizuho Nakayama, Noboru Manabe, Naoko Inoue, Toshikatsu Matsui, Hajime Miyamoto. Changes in the expression of tumor necrosis factor (TNF)_, TNF_ Receptor (TNFR) 2 and TNFR-associated factor 2 in granulosa cells during atresia in pig ovaries. Biology of Reproduction, 68 (2): 530-535, 2003.
43. Kohji Komatsu, Noboru Manabe, Minako Kiso, Munetake Shimabe, Hajime Miyamoto. Changes in localization of immune cells and cytokines in corpora lutea during luteolysis in murine ovaries. Journal of Experimental Zoology, 296 (1): 152-159, 2003.
44. Kohji Komatsu, Noboru Manabe, Minako Kiso, Munetake Shimabe, Hajime Miyamoto. Soluble Fas (FasB) regulates luteal cell apoptosis during luteolysis in murine ovaries. Molecular Reproduction and Development, 65: 345-352, 2003.
45. Toshikatsu Matsui, Noboru Manabe, Yasufumi Goto, Mizuho Nakayama, Naoko Inoue, Susumu Nishihara, Hajime Miyamoto. Changes in the expression and activity of caspase-9 and Apaf1 in granulosa cells during follicular atresia in pig ovaries. Reproduction, 126: 113-120, 2003.
46. Istvan Egerszegi, Falk Schneider, Jozsef R_tky, Ferenc So_s, L_szl_ Solti, Noboru Manabe, Klaus-Peter Br_ssow. Comparison of luteinizing hormone and steroid hormone secretion during the peri- and post-ovulatory periods in mangalica and landrace gilts. Journal of Reproduction and Devevelopment, 49: 291-296, 2003.
47. Naoko Inoue, Noboru Manabe, Toshikatsumatsui, Akihisa Maeda, Shynsuke Nakagawa, Satoko Wada, Hajime Miyamoto. Roles of tumor necrosis factor-related apoptosis-inducing ligand signaling pathway in granulosa cell apoptosis during atresia in pig ovaries. Journal of Reproduction and Devevelopment, 49: 313-321, 2003.
48. Satoshi Imanishi, Noboru Manabe, Hanako Nishizawa, Maki Morita, Miki Sugimoto, Mineko Iwahori, Hajime Miyamoto. Effects of oral exposure of bisphenol A on mRNA expression of nuclear receptors in murine placentae assessed by DNA microarray. Journal of Reproduction and Devevelopment, 49: 329-336, 2003.
49. Minako Kiso, Noboru Manabe, Kohji Komatsu, Munetake Shimabe, Hajime Miyamoto. Abnormal structural luteolysis in ovaries of the senescence accelerated mouse (SAM): expression of Fas Ligand/Fas-mediated apoptosis signaling molecules in luteal cells. Journal of Reproduction and Devevelopment, 49: 457-463, 2003.
50. Hanako Nishizawa, Noboru Manabe, Maki Morita, Miki Sugimoto, Satoshi Imanishi, Hajime Miyamoto. Effects of in utero exposure of bisphenol A on expression of RAR_ and RXR_ mRNAs in murine embryos. Journal of Reproduction and Devevelopment, 49: 539-545, 2003.
51. Kozue Uchio-Yamada, Noboru Manabe, Misuzu Yamaguchi-Yamada, Yasufumi Goto, Yoshie Yamamoto, Atsuo Ogura, Hajime Miyamoto. Changes in the localization of type I, III and IV collagen mRNAs in the kidneys of hereditary nephritic (ICGN) mice with renal fibrosis. The Journal of Veterinary Medical Science, 66: 123-128, 2004.
52. Ysufumi Goto, Noboru Manabe, Kozue Uchio, Misuzu Yamaguchi-Yamada, Naoko Inoue, Yoshie Yamamoto, Atsuo Ogura, Nobuo Nagano, Hajime Miyamoto. Myofibroblastic differentiation in tubulointerstitial cells is provoked by augmented cytoplasmic Smad4 protein in hereditary nephrotic ICGN mice with chronic renal fibrosis. Cell and Tissue Research, 315: 209-221, 2004.
53. Misuzu Yamaguchi-Yamada, Noboru Manabe, Kozue Uchio-Yamada, Naotsugu Akashi, Yasufumi Gotoh, Youhei Miyamoto, Masaya Nagao, Yoshie Yamamoto, Atsuo Ogura, Hajime Miyamoto. Anemia with chronic renal disorder and disrupted metabolism of erythropoietin in ICR-derived glomerulonephritis (ICGN) mice. The Journal of Veterinary Medical Science, 66: 423-431, 2004.
54. Misuzu Yamaguchi-Yamada, Noboru Manabe, Yshufumi Goto, Sayuri Anann, Keiko Miyamoto, Youhei Miyamoto, Masaya Nagao, Yoshie Yamamoto, Atsuo Ogura. Improvement of anemia associated with chronic renal failure by recombinant human erythropoietin treatment in ICR-derived glomerulonephritis (ICGN) mice. The Journal of Veterinary Medical Science, 66: 883-886, 2004.
55. Karin Wollenhaupt, Harald Welter, Ralf Einspanier, Noboru Manabe, Klaus-Peter Br_ssow. Expression of epidermal growth factor receptor (EGF-R)-, vascular endothelial growth factor receptor (VEGF-R) and fibroblast growth factor receptor (FGF-R) systems in porcine oviduct and endometrium during the time of implantation. Journal of Reproduction and Devevelopment, 50: 269-278, 2004.
56. Beum-Soo An, Kyung-Chul Choi, Eui-Ju Hong, Yong-Woo Jung, Noboru Manabe, Eui-Bae Jeung. differential transcriptional and translational regulations of calbindin-D9k by steroid hormones and their receptors in the uterus of immature mice. Journal of Reproduction and Devevelopment, 50: 445-453, 2004.
57. Yasufumi Goto, Fuko Matsuda, Toshikatsu Matsui, Akihisa Maeda, Naoko Inoue, Noboru Manabe. The porcine (Sus scrofa) cellular Flice-like inhibitory protein (cFLIP): molecular cloning and comparison with the human and murine cFLIP. Journal of Reproduction and Devevelopment, 50: 549-555, 2004.
58. Noboru Manabe, Yasufumi Goto, Fuko Matsuda-Minehata, Naoko Inoue, Akihisa Maeda, Miki Sugimoto, Kazuhiro Sakamaki, Tkashi Miyano. Regulation mechanism of selective atresia in porcine follicles: regulation of granulosa cell apoptosis during atresia. Journal of Reproduction and Devevelopment, 50: 493-514, 2004.
59. Kozue Uchio-Yamada, Noboru Manabe, Yasufumi Goto, Sayuri Anann, Yoshie Yamamoto, Kaoru Takano, Atsuo Ogura, Junichiro Matsuda. Decreased expression of matrix metalloproteinases and tissue inhibitors of metalloproteinase in the kidneys of hereditary nephrotic (ICGN) mice. The Journal of Veterinary Medical Science, 67: 35-41, 2005.
60. Noriko Kagawa, Yohichiro Sakurai, Takashi Miyano, Noboru Manabe. Effects of long-term grafting on follicular growth in porcine ovarian cortical grafts xenoplanted to severe combined immunodeficient (SCID) mice. Journal of Reproduction and Devevelopment, 51: 77-85, 2005.
61. Jozsef R_tky, Helmut Torner, Istvan Egerszegi, Falk Schneider, Peter Sarl_s, Noboru Manabe, Klaus-Peter Br_ssow. Ovarian activity and oocyte development during follicular development in pigs at different reproductive phases estimated by the repeated endoscopic method. Journal of Reproduction and Devevelopment, 51: 109-115, 2005.
62. Eui-Ju Hong, Youn-Kyu Ji, Kyung-Chul Choi, Noboru Manabe, Eui-Bae Jeung. Conflict of estrogenic activity by various phthalates between in vitro and in vivo models related to the expression of Calbindin-D9k. Journal of Reproduction and Devevelopment, 51: 253-263, 2005.
63. Yohei Miyamoto, Keiko Kuramitsu-Miyamoto, Ema iwanaga, Kozue uchio-yamada, Misuzu Yamaguchi-Yamada, Atsuo Ogura, Noboru Manabe. Effect of human erythropoietin (hEPO) treatment on anemia in ICR-derived glomerulaonephrosis (ICGN) mice. Experimental Animal 54: 181-184, 2005.
64. Yuko Kawamoto, Wakoto Matsuyama, Masahiro Morikawa, Maki Morita, Miki Sugimoto, Noboru Manabe, Shinsuke Morisawa. Disposition of bisphenol A in pregnant mice and fetuses after a single and repeated oral administration. Toxicological and Environmental Chemistry 87: 199-213, 2005.
65. Karin Wollenhaupt, Harald Welter, Ralf Einspanier, Noboru Manabe, Klaus-Peter Br_ssow. Expression of epidermal growth factor receptor (EGF-R), vascular endothelial growth factor receptor (VEGF-R) and fibroblast growth factor receptor (FGF-R) systems in porcine oviduct and endometrium during the time of implantation. Journal of Reproduction and Devevelopment, 51: **-**, 2005 (in press).
66. Hanako Nishizawa, Maki Morita, Miki Sugimoto, Satoshi Imanishi, Noboru Manabe. Effects of in utero exposure to bisphenol A on mRNA expression of arylhydrocarbon and retinoid receptors in murine embryos. Journal of Reproduction and Devevelopment, 51: **-**, 2005 (in press).
67. Fuko Matsuda-Minehata, Yasufumi Goto, Naoko Inoue, Noboru Manabe. Changes in expression of anti-apoptotic protein, cFLIP, in granulosa cells during follicular atresia in porcine ovaries. Molecular Reproduction and Development, 67: **-**, 2005 (in press).
68. Noriko Kagawa, Takashi Miyano, Noboru Manabe. Growth and maturation of porcine follicles and oocytes following xenotransplantation of ovarian tissues and in vitro maturation culture. Theriogenology, 67: **-**, 2005 (in press).
69. Misuzu Yamaguchi-Yamada, Noboru Manabe, Minako Kiso, Yasufumi Goto, Toshiharu Mori, Chinatsu Sakata, Sayuri Anan, Masaya Nagao, Yoshie Yamamoto, Atsuo Ogura. Dysfunction of erythropoietin-producing interstitial cells in the kidneys of ICR-derived glomerulonephritis (ICGN) mice. The Journal of Veterinary Medical Science, 67: **-**, 2005 (in press).
70. Hanako Nishizawa, Satoshi Imanishi, Noboru Manabe. Effects of exposure in utero to bisphenol A on the expression of arylhydrocarbon receptor, related factors and xenobiotic metabolizing enzymes in murine embryos. Journal of Reproduction and Devevelopment, 51: **-**, 2005 (in press).
2) REVIEWS1. Noboru Manabe, Hajime Miyamoto. Endocrine-disrupting environmental contaminants in animal products. Clinical Endocrinology, 46 (5): 555-562, 1998.
2. Ogura Atsuo, Mie Yamaguchi, Hisako Fujimura, Kotaro Tamura, Noboru Manabe. ICGN mouse as novel animal model for familial nephrosis. Pathology and Clinical Medicine, 16 (6): 729-736, 1998.
3. Noboru Manabe, Kozue Uchio, Miki Sugimoto, Hajime Miyamoto. Selection of oocytes in mammalian ovaries. Tissue Culture Engineering, 25 (1): 4-8, 1999.
4. Noboru Manabe, Kozue Uchio, Hajime Miyamoto. Endocrine-disrupting contaminants in animal products. Obstetrics and Gynaecology, 66 (2): 254-265, 1999.
5. Noboru Manabe, Miki Sugimoto. Structure biological approach for evaluation of malformation in mammalian embryos. Journal of Clinical and Experimental Medicine. 190 (7): 744-745, 1999.
6. Mizuho Nakayama, Shotaro Nisimura, Kaoru Okano, Hisao Iwamoto, Kozue Uchio, Noboru Manabe, Hajime Miyamoto. Immunohistochemical study of luteinizing hormone secretory cell and basic fibroblast growth factor in the goat pituitary gland. Japanese Journal of Embryo Transfer, 21 (1): 7-15, 1999.
7. Noboru Manabe, Miki Sugimoto, Maki Morita, Takako Tanaka, Misuzu Yamaguchi, Hajime Miyamoto. In vivo noninvasive nuclear magnetic resonance technique for assessment of teratogenicity induced by environmental pollutants. Environment Measurement and Chemical Analysis, 27 (1): 60-66, 2000.
8. Noboru Manabe, Miki Sugimoto, Maki Morita, Takako Tanaka, Misuzu Yamaguchi, Hajime Miyamoto. A novel in vivo 31P-nuclear magnetic resonance technique for assessment of teratogenicity induced by environmental endocrine disrupters in mice. Japanese Journal of Clinical Medicine, 58 (1): 108-111, 2000.
9. Miki Sugimoto, Noboru Manabe, and Hajime Miyamoto. Cryopreservation of mammarian ovarian tisssue. Tissue Culture Engineering, 26 (1): 48-51, 2000.
10. Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Future functional-morphological studies in embryology. Journal of Reproduction and Development, 46 (1): 71-77, 2000.
11. Tomiharu Mannda, Yoshiharu Mizokawa, Kouhichiro kaya, Masayuki Kitagawa, Atsushi Suzuki, Hideo Yano, Noboru Manabe, Tohru Matsui, Sennei Yamada and Yoshiyuki Sasaki. Course and prospect of animal science research in 21st century. Animal Science Journal, 71: 459-469, 2000.
12. Noboru Manabe, Miki Sugimoto, Mizuho Nakayama, Naoko Inoue, Minako Kiso, Misuzu Yamaguchi, Takako Tanaka, Kozue Yamada-Uchio, Hajime Miyamoto. Physiological roles of apoptosis in granulosa cells of atretic follicles in porcine ovaries. Japanese Journal of Embryo Transfer, 23 (1): 1-10, 2001.
13. Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Update on cryopreservation of mammalian ovaries. Obstetrics and Gynecology, 68 (2): 207-212, 2001.
14. Naoko Inoue, Akihiro Kiya, Noboru Manabe, Hajime Miyamotyo, Katsuhiro Fukuta. Elongation of cell cycle of early stage tetraploid murine embryos induced by cytochalasin B. Japanese Journal of Embryo Transfer, 23 (2): 44-51, 2001.
15. Noboru Manabe, Mizuho Nakayama, Misuzu Yamaguchi, Minako Kiso, Takako Tanaka, Naoko Inoue, Kozue Yamada-Uchio, Miki Sugimoto, Hajime Miyamoto. A novel cell death receptor and a decoy receptor on follicular granulose cells of porcine ovaries. Japanese Journal of Embryo Transfer, 23 (2): 52-60, 2001.
16. Yousuke Umezu, Hideki Tonomura, Takeshi Miyake, Yukio Taniguchi, Noboru Manabe, Takahisa Yamada, Yoshiyuki Sasaki. Detection of rat model useful for genetic analysis of intramascular fat accumulation. Journal of Animal Genetics, 29 (1): 3-10, 2001.
17. Noboru Manabe, Miki Sugimoto, Hajime Miyamoto. In vivo noninvasive nuclear magnetic resonance (NMR) technique for assessment of teratogenicity induced by chemicals. (Review) Chemical Engineering, 47 (2), 110-114, 2002.
18. Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Cryopreservation techniques for ovarian tissues. (Review) Hormone Frontier in Gynecology, 9: 135-140, 2002.
19. Noboru Manabe. Molecular mechanism of follicle selection in mammalian ovaries. (Review) Journal of Laboratory Animals (Kansai), 23 (1): 71-78, 2002.
20. Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Cryopreservation of ovarian tissue. (Review) Igakuno Ayumi, 204 (13): 921-925, 2003.
3) BOOKS
1. Noboru Manabe, Akira Myomoto, Yoshihiro Kimura, Yuzuru Imai, Miki Sugimoto, Kazuhiro Sakamaki, Yoshinori Okamura, Manabu Fukumoto, Hajime Miyamoto. Regulatory mechanisms of granulosa cell apoptosis in porcine ovarian follicle atresia. In: Reproductive Biology Update: Novel tools for assessment of environmental toxicity, Miyamoto H, Manabe N eds, Shokado Publisher Co, Kyoto, Japan, pp23-35 (total page 498), 1998.
2. Noboru Manabe, Tomohiko Okuda, Hiroaki Takakuwa, Miki Sugimoto, Hajime Miyamoto. Retinoids induce malformations related to cell death in mouse embryos. In: Reproductive Biology Update: Novel tools for assessment of environmental toxicity, Miyamoto H, Manabe N eds, Shokado Publisher Co, Kyoto, Japan, pp365-374 (total page 498), 1998.
3. Noboru Manabe, Yasuyoshi Azuma, Makoto Miyamoto, Keiko Kuramitsu, Yoshihiro Furuya, Nobuo Nagano and Hajime Miyamoto. Quantitative physiology estimated by histochemical and structure-biological measurement. In: Reproductive Biology Update: Novel tools for assessment of environmental toxicity, Miyamoto H, Manabe N eds, Shokado Publisher Co, Kyoto, Japan, pp469-481 (total page 498), 1998.
4. Noboru Manabe, Yoshihiro Kimura, Akira Myomoto, Hiroko Matsushita, Chiemi Tajima, Miki Sugimoto and Hajime Miyamoto. Role of granulosa cell apoptosis in ovarian follicle atresia. In: Reproductive Biology Update: Novel tools for assessment of environmental toxicity, Miyamoto H, Manabe N eds, Shokado Publisher Co, Kyoto, Japan, pp97-111 (total page 498), 1998.
5. Okamura Yshinori, Akira Myomoto, Xianlong Gao, Noboru Manabe, Nobuyuki Tanaka, Kouhei Matuura, Hitoshi Okamura, Hiroshi Hiai, Manabu Fukumoto. The role of protein tyrosine kinase in ovarian folliclogenesis. In: Reproductive Biology Update: Novel tools for assessment of environmental toxicity, Miyamoto H, Manabe N eds, Shokado Publisher Co, Kyoto, Japan, pp37-42 (total page 498), 1998.
6. Yoshihiro Kimura, Noboru Manabe, Hiroko Matushita, Yuzuru Imai, Miki Sugimoto and Hajime Miyamoto. Granulosa cell glycoconjugates found in atretic follicles of the pig ovary. In: Reproductive Biology Update: Novel tools for assessment of environmental toxicity, Miyamoto H, Manabe N eds, Shokado Publisher Co, Kyoto, Japan, pp59-66 (total page 498), 1998.
7. Myomoto Akira, Yoshinori Okamura, Xianlong Gao, Noboru Manabe, Hajime Miyamoto, Hiroshi Hiai, Manabu Fukumoto. Ovarian follicular atresia and development: Tyrosin kinase (TK) activity in relation to regulation of granulosa cell apoptosis. In: Reproductive Biology Update: Novel tools for assessment of environmental toxicity, Miyamoto H, Manabe N eds, Shokado Publisher Co, Kyoto, Japan, pp67-72 (total page 498), 1998.
8. Maki Morita, Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. The morphology of mammalian oviductal epithelium and its functional relevance. In: Reproductive Biology Update: Novel tools for assessment of environmental toxicity, Miyamoto H, Manabe N eds, Shokado Publisher Co, Kyoto, Japan, pp337-343 (total page 498), 1998.
9. Miki Sugimoto, Tadashi Kabasawa, Shinji Maeda, Noboru Manabe, Hajime Miyamoto. Organ cryopreservation of mammalian ovarian tissue as a means for preservation of female germ cells and ovarian endocrine function. In: Reproductive Biology Update: Novel tools for assessment of environmental toxicity, Miyamoto H, Manabe N eds, Shokado Publisher Co, Kyoto, Japan, pp439-448 (total page 498), 1998.
10. Makoto Miyamoto, Noboru Manabe, Keiko Kuramitsu, Yukinobu Kuribayashi, Kotaro Tamura, Yoshihiro Furuya, Nobuo Nagano, Manabu Fukumoto and Hajime Miyamoto. Lectin histochemistry in fibrotic liver disease. In: Reproductive Biology Update: Novel tools for assessment of environmental toxicity, Miyamoto H, Manabe N eds, Shokado Publisher Co, Kyoto, Japan, pp483-490 (total page 498), 1998.
11. Noboru Manabe, Yoshihiro Kimura, Kozue Uchio, Chiemi Tajima, Hiroko Matsushita, Mizuho Nakayama, Miki Sugimoto, Hajime Miyamoto. Regulatory mechanisms of granulosa cell apoptosis in ovarian follicle atresia: Role of granulosa cell apoptosis in porcine ovarian follicle atresia. In: Animal Cell Technology. Iikura K, Nagao M, Masuda S, Sasaki R eds, Kluwer Academic Pub, Dordrecht, The Nederlands, pp343-347 (total page 452), 1999.
12. Noboru Manabe. Reproductive organs and germinal cell differentiation. In: Reproductive Biology in Mammals. Takahashi M eds, Gakusoshya Pub. Co, Tokyo, Japan, pp86-91, 1999.
13. Noboru Manabe. Female reproductive organs. In: Veterinary Histology. Japanese Society of Veterinary Anatomists eds, Gakusoshya Pub. Co, Tokyo, Japan, pp281-306, 1999.
14. Noboru Manabe, Mizuho Nakayama, Misuzu Yamaguchi. Methods for in vitro studies of ovarian follicular cells. In: Methods for Reproductive Physiology. Sato E eds, Yokenndo Pub. Co, Tokyo, Japan, pp124-130, total page 406, 2000.
15. Noboru Manabe. Female reproductive organs. In: Veterinary Histology 2nd edition. Japanese Society of Veterinary Anatomists eds, Gakusoshya Pub. Co, Tokyo, Japan, pp280-305, total page 448, 2001.
16. Noboru Manabe, Miki Sugimoto, Mizuho Nakayama, Naoko Inoue, Toshikatsu Matsui, Misuzu Yamaguchi, Kozue Yamada-Uchio, Hajime Miyamoto. Histological and biochemical profiles of granulosa cell apoptosis in follicular atresia of porcine ovaries. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 61-72, 2001.
17. Noboru Manabe, Akira Myomoto, Chiemi Tajima, Mizuho Nakayama, Misuzu Yamaguchi, Naoko Inoue, Toshikatsu Matsui, Kozue Yamada-Uchio, Hajime Miyamoto. Cell death receptor dependent regulation of granulosa cell apoptosis in porcine ovarian follicle atresia. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 81-90, 2001.
18. Mizuho Nakayama, Noboru Manabe, Susumu Nishihara, Satoko Wada, Naoko Inoue, Toshikatsu Matsui, Hajime Miyamoto. Histochemical studies for comparison of regulatory mechanisms of follicular development in mammalian ovaries. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 91-98, 2001.
19. Minako Kiso, Kohji Komatsu, Noboru Manabe, Noriyuki Nisioka, Nami Nakai-Sugimoto, Hajime Miyamoto. An animal models for luteolysis: Abnormal accumulation of luteal bodies in ovaries of the senescence accelerated mouse (SAM). In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 121-124, 2001.
20. Maki Morita, Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Functions of mammalian oviducts and their relevance to morphology. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 127-131, 2001.
21. Noboru Manabe, Tomohiko Okuda, Miki Sugimoto, Takako Tanaka, Reika Okamoto, Minako Kiso, Kohji Komatsu, Misuzu Yamaguchi, Kozue Yamada-Uchio, Hajime Miyamoto. Teratosis induced by retinoids relates to apoptotic cell death in mouse embryos. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 167-176, 2001.
22. Miki Sugimoto, Noboru Manabe, Maki Morita, Takako Tanaka, Reika Okamoto, Hajime Miyamoto. Utilization of NMR microscopy in developmental toxicology: Assessment of mouse embryo malformations induced by maternal administration of retinoic acid. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 177-181, 2001.
23. Takako Tanaka, Noboru Manabe, Reika Okamoto, Miki Sugimoto, Hajime Miyamoto. Effects of endocrine disrupters on the expression of nuclear receptors in murine embryos. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 183-188, 2001.
24. Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Basic aspects of organ cryopreservation and application for preservation of mammalian ovarian tissue. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 341-346, 2001.
25. Kozue Yamada-Uchio, Noboru Manabe, Misuzu Yamaguchi, Kotaro Tamura, Naotsugu Akashi, Yasufumi Goto, Yoshie Yamamoto, Atsuo Ogura, Hajime Miyamoto. Abnormalities of extracellular matrix metabolisms in the kidney of ICGN mice, a strain of mice with hereditary nephrotic syndrome. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 361-372, 2001.
26. Misuzu Yamaguchi, Noboru Manabe, Kozue Yamada-Uchio, Naotsugu Akashi, Yasufumi Goto, Masaya Nagao, Yoshie Yamamoto, Atsuo Ogura, Hajime Miyamoto. Renal anemia in ICR-derived glomerulonephritis (ICGN) mice. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 373-377, 2001.
27. Noboru Manabe, Kozue Yamada-Uchio, Misuzu Yamaguchi, Kohji Komatsu, Nobuo Nagano, Yasuyoshi Furuya, Hajime Miyamoto. Quantitative estimation of physiological properties by histochemical techniques. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 397-404, 2001.
28. Noboru Manabe, Yasuyoshi Azuma, Miki Sugimoto, Misuzu Yamaguchi, Kozue Yamada-Uchio, Kohji Komatsu, Minako Kiso, Takako Tanaka, Hajime Miyamoto. In vivo 31P-nuclear magnetic resonance technique for estimation of liver energy metabolism in mice. In: Reproductive Biotechnology: Reproductive biotechnology update and its related physiology, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 424), 405-413, 2001.
29. Noboru Manabe, Naoko Inoue, Toshikatsu Matsui, Shinsuke Nakagawa, Akihisa Maeda, Takashi Miyano, Kazuhiro Sakamaki, Miki Sugimoto, Hajime Miyamoto. Regulatory mechanisms of follicle selection in mammalian ovaries. In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 117-132, 2003.
30. Noboru Manabe, Satoko Wada, Naoko Inoue, Toshikatu Matsui, Shinsuke Nakagawa, Akihisa Maeda, Hajime Miyamoto. Tumor necrosis factor-related apoptosis-inducing ligand and its receptors play crucial roles in apoptosis of granulosa cells during follicular atresia in pig ovaries. In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 133-142, 2003.
31. Mizuho Nakayama, Noboru Manabe, Naoko Inoue, Toshikatsu Matsui, Shinsuke Nakagawa, Akihisa Maeda, Hajime Miyamoto. Tumor necrosis factor-_ acts as a survival factor in granulosa cells during follicular selection in porcine ovaries. In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 143-149, 2003.
32. Naoko Inoue, Noboru Manabe, Toshikatsu Matsui, Shinsuke Nakagawa, Akihisa Maeda, Hajime Miyamoto. Roles of Fas-ligand and TRAIL systems in granulosa cell apoptosis during follicular atresia in porcine ovaries. In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 151-156, 2003.
33. Toshikatu Matsui, Noboru Manabe, Yasufumi Goto, Naoko Inoue, Shinsuke Nakagawa, Akihisa Maeda, Susumu Nishihara, Hajime Miyamoto. Role of the mitochondria-dependent pathway in granulosa cell apoptosis during follicular atresia in pig ovaries. In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 157-163, 2003.
34. Misuzu Yamaguchi-Yamada, Noboru Manabe, Kozue Uchio-Yamada, Naotsugu Akashi, Yasufumi Gotoh, Masaya Nagao, Yoshie Yamamoto, Atsuo Ogura, Hajime Miyamoto. Anemia associated with renal failure in the ICR-derived glomerulonephritis (ICGN) mice. In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 281-285, 2003.
35. Minako Kiso, Noboru Manabe, Kohji Komatsu, Munetake Shimabe And Hajime Miyamoto. Abnormal structural luteolysis in ovaries of the senescence accelerated mouse (SAM): expression of Fas mediated apoptosis signal in luteal bodies. In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 287-294, 2003.
36. Noboru Manabe, Kozue Yamada-Uchio, Misuzu Yamada-Yamaguchi, Yasufumi Gotoh, Toshiharu Mori, Chinatsu Sakata,Yoshihiro Furuya, Hajime Miyamoto. Histochemical technique quantitatively estimates the physiological and pathological properties. In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 303-309, 2003.
37. Maki Morita, Miki Sugimoto, Takako Tanaka, Satoshi Imanishi, Hanako Nishizawa, Kei-Ichi Sezaki, Mineko Iwahori, Noboru Manabe, Hajime Miyamoto. Morphological alterations in mammalian reproductive organ induced by exposure to diethylstilbestrol (DES). In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 319-323, 2003.
38. Miki Sugimoto, Noboru Manabe, Maki Morita, Kei-Ichi Sezaki, Takako Tanaka, Satoshi Imanishi, Hanako Nishizawa, Mineko Iwahori, Hajime Miyamoto. Utilization of magnetic resonance microscope for studies in reproductive toxicology. In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 325-330, 2003.
39. Noboru Manabe, Yasuyoshi Azuma, Miki Sugimoto, Kei-Ichi Sezaki, Mineko Iwahori, Satoshi Imanishi, Hanako Nishizawa, Takako Tanaka, Maki Morita, Hajime Miyamoto. In vivo and real time estimation of energy metabolism by 31p-nuclear magnetic resonance. In: Animal Frontier Science, Sato E, Miyamoto H, Manabe N eds, Hokuto Pub. Co, Kyoto, (total page: 363), 339-347, 2003.
40. Noboru Manabe, Naoko Inoue, Takashi Miyano, Kazuhiro Sakamaki, Miki Sugimoto, Hajime Miyamoto. Chapter 21. Ovarian follicle selection in mammalian ovaries: Regulatory mechanisms of granulosa cell apoptosis during follicular atresia. pp369-385. In: The Ovary, 2nd edition, Leung PK, Adashi E eds, Academic Press/Elsevier Science, Amsterdam, The Nederland, (ISBN: 0-12-444562-4), pp369-385 (total page 664), 2003.
41. Noboru Manabe. Female reproductive organs. In: Veterinary Histology 3rd edition. Japanese Society of Veterinary Anatomists eds, Gakusoshya Pub. Co, Tokyo, Japan, pp185-196, total page 315, 2003.
42. Noboru Manabe. The Ovary. In: Biology of Reproduction 2nd edition, Sato E eds, Asakura Pub. Co, Tokyo, Japan, pp185-196, total page 315, 2003.
43. Noboru Manabe, Minako Kiso, Munetake Shimabe, Nami Nakai-Sugimoto, Hajime Miyamoto. Abnormal accumulation of corpora lutea in ovaries of the senescence accelerated mouse prone (SAMP). The Senescence-Accelerated Mouse (SAM): An Animal Model of Senescence, Yasuyuki Nomura, Toshio Takeda, Yasunobu Okuma eds, Elsevier Science Publishers B.V., Amsterdam, The Nederland, pp179-185, total page 448, 2004.
44. Munetake Shimabe, Minako Kiso, Kohji Komatsu, Noboru Manabe, Hajime Miyamoto. Expression of matrix metalloproteinase (MMP) and tissue inhibitor of MMP in ovaries of senescence accelerated mice. The Senescence-Accelerated Mouse (SAM): An Animal Model of Senescence, Yasuyuki Nomura, Toshio Takeda, Yasunobu Okuma eds, Elsevier Science Publishers B.V., Amsterdam, The Nederland, pp229-232, total page 448, 2004.
45. Minako Kiso, Munetake Shimabe, Kohji Komatsu, Noboru Manabe, Hajime Miyamoto. Expression of prolactin receptor mRNA in ovaries of senescence accelerated mice. The Senescence-Accelerated Mouse (SAM): An Animal Model of Senescence, Yasuyuki Nomura, Toshio Takeda, Yasunobu Okuma eds, Elsevier Science Publishers B.V., Amsterdam, The Nederland, pp233-236, total page 448, 2004.
4) PROSEEDINGS
1. Maki Morita, Miki Sugimoto, Nami Sugimoto, Noboru Manabe, Hajime Miyamoto. Ampulla and isthmus of mouse oviduct show characteristic morphological changes during the estrous cycle. In: Gametes: Development and Function, Lauria A, Gandolfi F, Enne G, Gianaroli L eds, Serono Symposia, Tabloid S.R.L., Rome, Italy, pp582, (1998).
2. Miki Sugimoto, Sinji Maeda, Noboru Mnabe, Hajime Miyamoto. Development and function of infantile rat ovaries cryopreserved by vitrification. Biology of Reproduction, 568: 180, (1998).
3. Hajime Miyamoto, Miki Sugimoto, Tomohiko Okuda, Yohichi Takahagi, Noboru Manabe. Assessment of the effect of dimethyl sulfoxide on the survival of cryopreserved mouse morulae by single step exposure and rapid freezing. Theriogenology, 49 (1): 171, (1998).
4. Maki Morita, Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Changes on morphological properties in mouse oviduct ampulla. Biology of Reproduction, 60: 144, (1999).
5. Yoshihiro Kimura, Mizuho Nakayama, Noboru Manabe, Hajime Miyamoto Glycobiological characteristics in granulosa cells during follicular atresia in the porcine ovary. Biology of Reproduction, 60: 221, (1999).
6. Noboru Manabe, Miki Sugimoto, Yasuyoshi Azuma, Takako Tanaka, Minako Kiso, Kozue Uchio, Hajime Miyamoto. A novel in vivo NMR technique to assess halocarbon induced hepatic failure in mice. In: Proceedings of the 3rd International Water Association Conference on Hazard Assessment and Control of Environmental Contaminants (EcoHazard 99), Matsui S eds, IWA Conference Committee, Kyoto, Japan, pp401-407, (1999).
7. Noboru Manabe, Chiemi Tajima, Miszuho Nakayama, Hajime Miyamoto. Immunochemical characteristics of a novel cell death receptor and a decoy receptor on granulosa cells of porcine ovarian follicles. In: Proceedings of the 15th International Symposium on Morphological Sciences, Japanese Society of Histochemistry and Cytochemistry, Kyoto, Japan, pp172, (2000).
8. Miszuho Nakayama, Kozue Yamada-Uchio, Noboru Manabe, Hajime Miyamoto. Localization of type I, III and IV collagens and their mRNA in porcine and bovine ovarian follicles. In: Proceedings of the 15th International Symposium on Morphological Sciences, Japanese Society of Histochemistry and Cytochemistry, Kyoto, Japan, pp173, (2000).
9. Maki Morita, Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Immunochemical characteristics of a novel cell death receptor and a decoy receptor on granulosa cells of porcine ovarian follicles. In: Proceedings of the 15th International Symposium on Morphological Sciences, Japanese Society of Histochemistry and Cytochemistry, Kyoto, Japan, pp174, (2000).
10. Miki Sugimoto, Maki Morita, Noboru Manabe, Hajime Miyamoto. NMR microscopic assessment of malformations in murine embryos induced by maternal administration of retinoic acid. In: Proceedings of the 15th International Symposium on Morphological Sciences, Japanese Society of Histochemistry and Cytochemistry, Kyoto, Japan, pp283 (2000).
11. Maki Morita, Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Morphological features of goat ampulla oviduct. In: Proceedings of 14th International Congress on Animal Reproduction, Stockholm, Sweden, pp150, (2000).
12. Maki Morita, Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. The conditions of oviduct secretion from mouse ampulla. Theriogenology, 53 (1): 171, (2000).
13. Mizuho Nakayama, Noboru Manabe, Susumu Nishihara, Hajime Miyamoto. Species-specific differentiation in apoptosis in granulosa cells during follicular atresia in sows and cows. Journal of Reproduction and Fertility 26: 20-21, (2000).
14. Noboru Manabe, Chiemi Tajima, Mizuho Nakayama, Minako Kiso, Kozue Uchio, Miki Sugimoto, Hajime Miyamoto. A novel cell death receptor and a decoy receptor on granulosa cells of porcine ovarian follicles. In: Proceedings of the Joint Meeting of the 2nd Sendai Symposium on Follicular Development and Atresia in Mammals and the 5th Asian Symposium on Animal Biotechnology, Sendai, Japan, pp16-27, (2000).
15. Noboru Manabe, Mizuho Nakayama, Naoko Inoue, Toshikatu Matsui, Akira Myoumoto, Chiemi Tajima, Takashi Miyano, Kazuhiro Sakamaki, Miki Sugimoto, Hajime Miyamoto. Molecular regulatory mechanisms of granulosa cell apoptosis during follicular atresia in porcine ovaries. In: Proceedings of The 1st Asian-Pacific Conference on Reproductive Biology and Environmental Sciences, Cheongju, Korea, pp49-53, (2001).
16. Miki Sugimoto, Noboru Manabe, Maki Morita, Takako Tanaka, Reika Okamoto Satoshi Imanishi, Hajime Miyamoto. Utilization of magnetic resonance microscopy in reproductive toxicology. In: Proceedings of The 1st Asian-Pacific Conference on Reproductive Biology and Environmental Sciences, Cheongju, Korea, pp185-190, (2001).
17. Maki Morita, Miki Sugimoto, Takako Tanaka, Reika Okamoto, Satoshi Imanishi, Noboru Manabe, Hajime Miyamoto. Diethylstilbestrol (DES) induces morphological alterations in offspring. In: Proceedings of The 1st Asian-Pacific Conference on Reproductive Biology and Environmental Sciences, Cheongju, Korea, pp195-199, (2001).
18. Takako Tanaka, Noboru Manabe, Reika Okamoto, Maki Morita, Miki Sugimoto, Hajime Miyamoto. Effects of endocrine disruptors on the expression of nuclear receptors in murine embryos. In: Proceedings of The 1st Asian-Pacific Conference on Reproductive Biology and Environmental Sciences, Cheongju, Korea, pp208-212, (2001).
19. Minako Kiso, Kohji Komatsu, Munetake Shimabe, Noboru Manabe, Noriyuki Nishioka, Nami Nakai-Sugimoto, Hajime Miyamoto. An animal model of luteolysis: abnormal accumula-tion of luteal bodies in ovaries of the senescence accelerated mouse (SAM). In: Proceedings of The 1st Asian-Pacific Conference on Reproductive Biology and Environmental Sciences, Cheongju, Korea, pp213-218, (2001).
20. Misuzu Yamaguchi, Noboru Manabe, Kozue Uchio-Yamada, Naotsugu Akashi, Yasufumi Gotoh, Youhei Miyamoto, Masaya Nagao, Yoshie Yamamoto, Atsuo Ogura, Hajime Miyamoto. Disrupted erythropoietin (EPO) metabolism in the kidneys of hereditary nephrotic (ICGN) mice. In: Proceedings of The 1st Asian-Pacific Conference on Reproductive Biology and Environmental Sciences, Cheongju, Korea, pp227-231, (2001).
21. Mizuho Nakayama, Noboru Manabe, Naoko Inoue, Toshikatsu Matsui, Hajime Miyamoto. Histochemical studies for comparison of regulatory mechanisms of follicular development in mammalian ovaries. In: Proceedings of The 1st Asian-Pacific Conference on Reproductive Biology and Environmental Sciences, Cheongju, Korea, pp243-247, (2001).
22. Maki Morita, Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Changes in morphology of mouse oviduct ampulla during early pregnancy. Biology of Reproduction, 64: 325, (2001).
23. Maki Morita, Miki Sugimoto, Takako Tanaka, Reika Okamoto, Noboru Manabe, Hajime Miyamoto. Morphological abnormalities of mouse female reproductive organ exposed to diethylstilbestrol in utero. Reproduction, 27: 21, (2001).
24. Noboru Manabe, Miki Sugimoto, Satoshi Imanishi, Hanako Nishizawa, Takako Tanaka, Maki Morita, Hajime Miyamoto. A novel in vivo nuclear magnetic resonance (NMR) technique to assess the toxicity of environmental pollutants. In: Proceedings of the 5th Scientific Congress of the Federation of Asian and Oceanian Physiological Societies (FAOPS), Kuala Lumpur, Malaysia, pp77-79, (2002).
25. Kazuhiro Sakamaki, Katsuya Kominami, Shin-Ichi Sakata, Noboru Manabe, Sin Yonehara. Apoptotic signaling machinery in the reproductive organs. In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp15-19, (2002).
26. Naoko Inoue, Toshikatsu Matsui, Shinsuke Nakagawa, Akihisa Maeda, Hajime Miyamoto, Noboru Manabe. Regulation mechanism of Fas ligand and Fas during follicle atresia in porcine ovary. In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp109-111, (2002).
27. Toshikatsu Matsui, Naoko Inoue, Yasufumi Goto, Shinsuke Nakagawa, Akihisa Maeda, Hajime Miyamoto, Noboru Manabe. Physiological cell death : mitochondrion dependent signaling system that regulate apoptosis in granulosa cells of pig ovaries. In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp112-113, (2002).
28. Noriko Kagawa, Hiroko Ishii, Masako Kadota, Hajime Miyamoto, Takashi Miyano, Noboru Manabe. Swine follicular development and atresia in ovarian tissues xenoplantated in the kidneys of SCID mice. In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp114-115, (2002).
29. Minako Kiso, Kohji Komatsu, Munetake Shimabe, Hajime Miyamoto, Noboru Manabe. An animal model of luteolysis: abnormal accumula-tion of luteal bodies in ovaries of the senescence accelerated mouse (SAM). In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp116-119, (2002).
30. Kohji Komatsu, Minako Kiso, Munetake Shimabe, Hajime Miyamoto, Noboru Manabe. The cytokines regulate the FasL/Fas system in the corpora lutea of the mouse. In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp120-121, (2002).
31. Misuzu Yamaguchi-Yamada, Noboru Manabe, Kozue Uchio-Yamada, Yasufumi Goto, Masaya Nagao, Yoshie Yamamoto, Ats, Hajime Miyamoto. Renal anemia and disrupted regulation of erythropoietin (EPO) in hereditary nephrotic (ICGN) mice. In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp147-150, (2002).
32. Miki Sugimoto, Noboru Manabe, Maki Morita, Kei-Ichi Sezaki, Takako Tanaka, Satoshi Imanishi, Mineko Iwahori, Hajime Miyamoto. Assessment of physiological and pathological status of male reproductive organs in mice by nuclear magnetic resonance techniques. In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp212-214, (2002).
33. Maki Morita, Miki Sugimoto, Takako Tanaka, Satoshi Imanishi, Hanako Nishizawa, Keiichi Sezaki, Mineko Iwahori, Noboru Manabe, Hajime Miyamoto. In utero exposure to diethylstilbestrol (DES) induces morphological alterations on mice reproductive tracts. In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp215-218, (2002).
34. Satoshi Imanishi, Noboru Manabe, Takako Tanaka, Reika Okamoto, Maki Morita, Miki Sugimoto, Hajime Miyamoto. Transition of mRNA expression of GPRC5b/Raig2, a novel orphan receptor, in murine placentae. In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp219-220, (2002).
35. Hanako Nishizawa, Satoshi Imanishi, Reika Okamoto, Takako Tanaka, Maki Morita, Miki Sugimoto, Noboru Manabe, Hajime Miyamoto. Transition of mRNA expression of retinoid X receptor _ in murine fetus. In: Proceedings of The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp221-222, (2002).
36. Noboru Manabe, Yuka Akiyama, Miki Sugimoto, Minako Kiso. Kohji Komatsu, Munetake Shimabe, Hajime Miyamoto. A morphometric analysis of testicular function in senescence accelerated mice. In: Proceedings of 27th Annual Meeting of the American Society of Andrology, Seattle, Washington, USA, pp49, (2002).
37. Satoshi Imanishi, Noboru Manabe, Miki Sugimoto, Hajime Miyamoto. Changes in mRNA expression of GPRC5B/Raig2, a novel orphan receptor, in mouse placenta during late gestation. Biology of Reproduction, 67: 154, (2003).
38. Miki Sugimoto, Noboru Manabe, Maki Morita, Kei-Ichi Sezaki, Takako Tanaka, Satoshi Imanishi, Hanako Nishizawa, Mineko Iwahori, Hajime Miyamoto. NMR spectroscopic assessment of effects of estrogenic compounds on male reproductive organs in mice. Biology of Reproduction, 67: 186, (2003).
39. Noboru Manabe, Naoko Inoue, Chiemi Tajima, Toshikatsu Matsui, Shinsuke Nakagawa, Akihisa Maeda, Hajime Miyamoto. Monoclonal antibodis recognize novel cell death receptors of granulosa cells in pig ovaries. Biology of Reproduction, 67: 234, (2003).
40. Naoko Inoue, Noboru Manabe, Toshikatsu Matsui, Shinsuke Nakagawa, Akihisa Maeda, Hajime Miyamoto. Changes in expression of Fas-dependent apoptotic signaling molecules in granulosa cells during folliclar atresia in pig ovaries. Biology of Reproduction, 67: 235, (2003).
41. Noboru Manabe, Minako Kiso, Munetake Shimabe, Nami Nakai-Sugimoto Hajime Miyamoto. Abnormal accumulation of corpora lutea in ovaries of the senescence accelerated mouse prone (SAMP). In: Proceedings of the 2nd International Conference on Senescence: The SAM model. The Council for SAM Research, Sapporo, Japan, pp58, (2003).
42. Munetake Shimabe, Minako Kiso, Kohji Komatsu, Noboru Manabe, Hajime Miyamoto. Expression of matrix metalloproteinase (MMP) and tissue inhibitor of MMP in ovaries of senescence accelerated mice. In: Proceedings of the 2nd International Conference on Senescence: The SAM model. The Council for SAM Research, Sapporo, Japan, pp66, (2003).
43. Minako Kiso, Munetake Shimabe, Kohji Komatsu, Noboru Manabe, Hajime Miyamoto. Expression of prolactin receptor mRNA in ovaries of senescence accelerated mice. In: Proceedings of the 2nd International Conference on Senescence: The SAM model. The Council for SAM Research, Sapporo, Japan, pp67, (2003).
44. Mizuho Nakayama, Noboru Manabe, Naoko Inoue, Toshikatus Matui, Hajime Miyamoto. The expression and localization of tumor necrosis factor (TNF) _, TNF_ receptor (TNFR) 2 and TNFR-associated factor 2 during follicular atresia in pig ovaries. Theriogenology, 59 (1): 411, (2003).
45. Naoko Inoue, Mizuho Nakayama, Toshikatsu Matsui, Akihisa Maeda, Hajime Miyamoto, Noboru Manabe. Roles of death receptors during follicular atresia in porcine ovaries. In: Proceedings of the 5th World Conference of the International Association of Private Assisted Reproductive Technology Clinics and Laboratories (APART), Tokyo, Japan, pp263, (2003).
46. Noriko Kagawa, Yoichiro Sakurai, Takashi Miyano, Hajime Miyamoto, Noboru Manabe. Follicular development in porcine ovarian tissues following xenografting into the kidneys of severe combined immunodeficient (SCID) mice. In: Proceedings of the 5th World Conference of the International Association of Private Assisted Reproductive Technology Clinics and Laboratories (APART), Tokyo, Japan, pp264, (2003).
47. Noboru Manabe, Naoko Inoue, Yasufumi Goto, Fuko Matsuda, Akihisa Maeda, Sayuri Anan, Miki Sugimoto. Follicle selection in porcine ovaries: regulation of granulosa cell apoptosis during atresia. In: Proceedings of the 1st Conference of Asian Reproductive Biotechnology (ARB). The Committee of the ARB, pp17-21, (2004).
48. Noboru Manabe, Yasufumi Goto, Hanako Nishizawa, Satoshi Imanishi, Sayuri Anan, Miki Sugimoto. Novel real-time and supersensitive techniques to assess the reproductive toxicity of environmental pollutants: in vitro fluorescence resonance energy transfer (FRET) technique and in vivo functional nuclear magnetic resonance (NMR) imaging technique. In: Proceedings of the 6th Congress of the Federation of Asian and Oceanian Physiological Societies (FAOPS) and 19th Scientific Meeting of the Malaysian society of pharmacology and physiology (MSPP), Kuala Lumpur, Malaysia, pp45-48 (total page 366), 2004.
49. Noboru Manabe, Kohji Komatsu, Minako Kiso, Yasufumi Goto, Sayuri Anan, Miki Sugimoto, Hajime Miyamoto. Luteal cell apoptosis is regulated by soluble fas during luteolysis in the mouse. Journal of Histochemistry and Cytochemistry, 52 (1): 30-31, (2004).
50. Chinatsu Sakata, Kozue Uchio-Yamada, Misuzu Yamaguchi-Yamada, Yasufumi Goto, Toshiharu Mori, Sayuri Anan, Atsuo Ogura, Yoshie Yamamoto, Noboru Manabe. Abnormal laminin expression in glomeruli of ICR-derived glomerulonephritis (ICGN) mice. Journal of Histochemistry and Cytochemistry, 52 (1): 34-35, (2004).
51. Misuzu Yamaguchi-Yamada, Yasufumi Goto, Chinatsu Sakata, Toshiharu Mori, Sayuri Anan, Yoshie Yamamoto, Atsuo Ogura, Noboru Manabe. Pathogenic mechanism of renal anemia in hereditary nephrotic ICGN mice. Journal of Histochemistry and Cytochemistry, 52 (1): 36-37, (2004).
52. Yasufumi Goto, Kozue Uchio, Misuzu Yamaguchi-Yamada, Naoko Inoue, Chinatsu Sakata, Toshiharu Mori, Sayuri Anan, Noboru Manabe. Increased Smad4 accelerates TGF-beta1 signaling and is involved in myofibroblastic differentiation in tubulointerstitial cells in kidneys of ICGN mice. Journal of Histochemistry and Cytochemistry, 52 (1): 42-43, (2004).
53. Hanako Nishizawa, Noboru Manabe, Satoshi Imanishi, Miki Sugimoto. Effects of in utero exposure to bisphenol a on mRNA expression of arylhydrocarbon and retinoid receptors in murine embryos. Biology of Reproduction, 68: 114, (2004).
54. Miki Sugimoto, Naoko Inoue, Maki Morita, Hajime Miyamoto, Noboru Manabe. Expression of decoy receptor-3 in porcine ovarian follicles. Biology of Reproduction, 68: 138, (2004).
55. Noriko Kagawa, Yoichiro Sakurai, Takashi Miyano, Noboru Manabe. Follicular development in porcine ovarian tissue following xenografting into the kidney of immunodeficient-SCID mouse. Biology of Reproduction, 68: 194, (2004).
56. Noboru Manabe, Toshikatsu Matsui, Yasufumi Goto, Fuko Matsuda, Naoko Inoue, Akihisa Maeda, Yuan Cheng, Sayuri Anan. Granulosa cell in porcine ovarian follicle is type II, mitochondrion-dependent, apoptotic cell. Biology of Reproduction, 68: 198, (2004).
57. Fuko Matsuda, Yasufumi Goto, Toshikatsu Matsui, Naoko Inoue, Sayuri Anan, Yuan Cheng, Kazuhiko Imakawa, Noboru Manabe. Anti-apoptotic protein, FLIP, is expressed in granulosa cells of porcine ovarian follicles. Biology of Reproduction, 68: 200, (2004).
58. Minako Kiso, Noboru Manabe, Munetake Shimabe, Yasufumi Goto, Sayuri Anan, Yuan Cheng, Hajime Miyamoto. Incompetence of luteolysis in ovaries of SAM mouse: abnormality in Fas ligand/Fas-mediated apoptosis signaling molecules in luteal cells. Biology of Reproduction, 68: 201, (2004).
59. Naoko Inoue, Mizuho Nakayama, Fuko Matuda, Yasufumi Goto, Akihisa Maeda, Yuan Cheng, Sayuri Anan, Noboru Manabe. Changes in mRNA expression of TNF and receptor family in granulosa cells during folliclar atresia in pig ovaries. Biology of Reproduction, 68: 276, (2004).
60. Yasufumi Goto, Sayuri Anan, Kozue Uchio-Yamada, Misuzu Yamaguchi-Yamada, Noboru Manabe. Augmented cytoplasmic Smad4 accelerates TGF beta1 signaling and promotes myofibroblastic differentiation in fibrogenic cells of ICGN-mice with renal fibrosis. Anatomical Science International, 79: 247, (2004).
61. Chinatsu Sakata, Kozue Uchio-Yamada, Misuzu Yamaguchi-Yamada, Yasufumi Goto, Sayuri Anan, Atsuo Ogura, Yoshie Yamamoto, Noboru Manabe. Immature glomerular basement membrane component laminin beta1 (Lb1) expression in ICR-derived glomerulonephritis (ICGN) mice. Anatomical Science International, 79: 248, (2004).
62. Noboru Manabe, Toshikatsu Matsui, Yasufumi Goto, Fuko Matsuda, Naoko Inoue, Akihisa Maeda, Yuan Cheng, Sayuri Anan. Type II, mitochondrion-dependent apoptosis occurs in granulosa cells during follicular atresia in porcine ovaries. Anatomical Science International, 79: 253, (2004).
63. Hanako Nishizawa, Satoshi Imanishi, Miki Sugimoto, Noboru Manabe. Effects of in utero exposure to bisphenol A on mRNA expression of arylhydrocarbon and retinoid receptors in murinre embryos. Anatomical Science International, 79: 254, (2004).
64. Miki Sugimoto, Maki Morita, Kei-Ichi Sezaki, Satoshi Imanishi, Hanako Nishizawa, Hajime Miyamoto, Noboru Manabe. Examination of murine male reproductive organs using magnetic resonance (NMR) techniques: an application to assessment of effects of estrogen. Anatomical Science International, 79: 255, (2004).
65. Noriko Kagawa, Yoichiro Sakurai, Takashi Miyano, Noboru Manabe. Follicular development in porcine ovarian tissue following xenografting into the kidney of SCID mice. Anatomical Science International, 79: 257, (2004).
66. Maki Morita, Miki Sugimoto, Satoshi Imanishi, Hanako Nishizawa, Hajime Miyamoto, Noboru Manabe. In utero exposure to diethylstilbestrol (DES) induces alterations in juvenile mouse uteri. Anatomical Science International, 79: 259, (2004).
67. Fuko Matsuda, Yasufumi Goto, Naoko Inoue, Toshikatsu Matsui, Sayuri Anan, Yuan Cheng, Kazuhiko Imakawa, Noboru Manabe. Identification of porcine cFLIP and its expression in ovarian granulosa cells. Anatomical Science International, 79: 264, (2004).
68. Naoko Inoue, Fuko Matsuda, Yasufumi Goto, Sayuri Anan, Yuan Cheng, Kazuhiro Sakamaki, Noboru Manabe. Porcine caspase-8 and FADD (Fas-associated death domain) can induce apoptosis in human cells. Anatomical Science International, 79: 265, (2004).
69. Tomohiro Yonezawa, Kazutaka Mogi, Junyou Li, Ryuji Sako, Toru Sawasaki, Noboru Manabe, Masatoshi Suzuki, Keitaro Yamanouchi, Masugi Nishihara. Changes in pulsatile pattern of growth hormone secretion and insulin-like growth factor levels during estrous cycle in shiba goats. In: Proceedings of the 3rd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp77-78, (2004).
70. Noboru Manabe, Toshikatsu Matsui, Yasufumi Goto, Naoko Inoue, Fuko Matsuda, Akihisa Maeda, Yuan Cheng, Sayuri Anann. Granulosa cell in porcine ovarian follicle is mitochondrion dependent type ii apoptotic cell. In: Proceedings of the 3rd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp79-80, (2004).
71. Fuko Matsuda, Yasufumi Goto, Toshikatsu Matsui, Naoko Inoue, Yuan Cheng, Sayuri Anann, Noboru Manabe. Cellular FLIPs (intracellular anti-apoptotic proteins) are expressed in follicular granulosa cells of porcine ovaries. In: Proceedings of the 3rd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp81-82, (2004).
72. Naoko Inoue, Mizuho Nakayama, Fuko Matuda, Yasufumi Goto, Akihisa Maeda, Yuan Cheng, Sayuri Anan, Noboru Manabe. Changes in expression of TNF and receptor family mRNAs in porcine granulosa cells during folliclar atresia. In: Proceedings of the 3rd Pacific Conference on Reproductive Biology and Environmental Sciences, Kyoto, Japan, pp83-84, (2004).
『秘蔵宝鑰』
淳和天皇の天長年間(824～834)、法相(ほっそう)・三論・華厳(けごん)・律・天台・真言の6宗に、各宗派の教義をしるして提出せよという勅命がくだった。真言宗では、空海みずからが『秘密曼荼羅十住心論』(十住心論)をあらわし、830年に提出したが、これは引用も多く、10巻にのぼる大部のものとなった。そこで空海は、『十住心論』の内容を抄出した『秘蔵宝鑰(ひぞうほうやく)』3巻を執筆。緻密な文体で、教義の趣旨を簡潔にあらわした。人間の心が浅薄な状態からしだいに高まり、密教の究極の智恵に達するまでを段階的にしめしたものだが、それは同時に、当時の社会思想や先行宗派に深浅の段階をつける試みでもあった。すなわち1～3は外道(1=欲望人、2=儒教、3=道教)、4～5は小乗(4=声聞、5=縁覚)、6～7は権大乗(6=法相、7=三論)、8～9は実大乗(8=天台、9=華厳)をあらわし、これら「顕教」に対する密教の優位性を説くのである。 我、今、詔を蒙(こうむ)つて十住を撰す 頓(とみ)に三妄を越えて心真に入らしめん 霧を_(かか)げて光を見るに無尽の宝あり 自他受用(じたじゅゆう) 日に弥(いよいよ)、新なり _祖(ばっそ)して伽梵(がぼん)を求む 幾郵(いくうまや)してか本床に到る 如来(にょらい)明らかにこれを説きたまへり 十種にして金場(こんじょう)に入る 已(すで)に住心の数(しゅ)を聴きつ 請ふ彼の名相を開け 心の名は後に明らかに列ぬ 諷読(ふどく)して迷方を悟れ［現代語訳］ わたくしは、今、淳和帝のご命令を受けて、「十住心」についての著作を書いた すみやかに、あらゆる迷いを克服して真実の心の世界に人びとをして入らしめたいと思う次第である 迷いの霧をのぞいて日の光を見ると、そこには無尽の宝がある 自分も他の者も共にこれを用いて、日々に新しく、尽きることがない 心を発(おこ)して仏を求めようとするが 本来のさとりの世界に達するのはどれだけ経(た)ってのことだろうか 如来はこのことを明らかにお説きになられた 心の世界を十種に分け、その階梯を経て永遠のさとりの世界に入ることができる すでに住心の数は聞くことができた 願わくはその名称と内容について開示されたい 心の名称はすぐあとで明らかに列挙する これをよく読んで、行方の迷いをさとっていただきたい
第一異生羝羊心(いしょうていようしん)凡夫狂酔して 吾が非を悟らず。 但し婬食(いんじき)を念ずること 彼の羝羊の如し。［現代語訳］ 無知な者は迷って、わが迷いをさとっていない。雄羊のように、ただ性と食とのことを思いつづけるだけである。
第二愚童持斎心
外の因縁に由(よ)つて 忽(たちま)ちに節食(せつじき)を思ふ。 施心萌動(ほうどう)して 穀の縁に遇ふが如し。［現代語訳］ 他の縁によって、たちまちに節食を思う。他の者に与える心が芽ばえるのは、穀物が播(ま)かれて発芽するようなものである。
外道天に生じて 暫(しばら)く蘇息を得(う)。 彼の嬰児と 犢子(とくし)との母に随ふが如し。［現代語訳］ 天上の世界に生まれて、しばらく復活することができる。それはおさな児や子牛が母にしたがうようなもので、一時の安らぎにすぎない。
ただ法有を解(げ)して 我人皆遮す。 羊車の三蔵 ことごとくこの句に摂す。［現代語訳］ ただ物のみが実在することを知って、個体存在の実在を否定する。教えを聞いてさとる者の説は、すべてこのようなものである。
第五抜業因種心(ばつごういんじゅしん)身を十二に修して 無明、種を抜く。 業生、已(すで)に除いて 無言に果を得。［現代語訳］ 一切は因縁よりなることを体得して、無知のもとをとりのぞく。このようにして迷いの世界を除いて、ただひとり、さとりの世界を得る。
無縁に悲を起して 大悲初めて発(おこ)る。 幻影に心を観じて 唯識、境を遮す。［現代語訳］ 一切衆生に対して計らいない愛の心を起こすことによって、大なる慈愛がはじめて生ずる。すべての物を幻影と観じて、ただ心のはたらきのみが実在であるとする。
第七覚心不生心(かくしんふしょうしん)八不(はっぷ)に戯(け)を絶ち 一念に空(くう)を観(み)れば、 心原空寂にして 無相安楽なり。［現代語訳］ あらゆる現象の実在を否定することによって実在に対する迷妄を断ち切り、ひたすら空を観ずれば、心は静まって何らの相(すがた)なく安楽である。
一如本浄にして 境智倶(とも)に融す。 この心性を知るを 号して遮那(しゃな)といふ。［現代語訳］ 現象はわけへだてなく清浄であって、認識における主観も客観もともに合一している。そのような心の本性を知るものを称して、仏(報身としての大日如来)というのである。
第九極無自性心(ごくむじしょうしん)水は自性なし 風に遇ふてすなはち波たつ。 法界は極にあらず 警を蒙(こうむ)つて忽(たちま)ちに進む。［現代語訳］ 水にはそれ自体の定まった性(しょう)はない。風にあって波が立つだけである。さとりの世界はこの段階が究極ではないという戒めによって、さらに進む。
第十秘密荘厳心(ひみつしょうごんしん)顕薬塵(ちり)を払ひ 真言、庫(くら)を開く。 秘宝忽ちに陳じて 万徳(まんどく)すなはち証す。［現代語訳］ 密教以外の一般仏教は塵を払うだけで、真言密教は庫の扉を開く。そこで庫の中の宝はたちまちに現われて、あらゆる価値が実現されるのである。
2005.7.2
Home